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Employment (2)

Taipei Medical University Hospital: Taipei, TW

2022-07 to present | Assistant Professor (Department of Physiology, School of Medicine)
Employment
Source: Self-asserted source
Yuh-Charn Lin

Academia Sinica: Taipei, TW

2018-08 to 2022-07 | Research Scholar (Institute of Biomedical Science)
Employment
Source: Self-asserted source
Yuh-Charn Lin

Works (28)

Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury

Journal of Microbiology, Immunology and Infection
2024-07 | Journal article | Author
DOI: 10.1016/j.jmii.2024.07.006
Part of ISSN: 1684-1182
Contributors: KUO-HUA Lee; Yuh-Charn Lin; Ming-Tsun Tsai; Cheng-Fen Tu; Shuo-Ming Ou; Huan-Yuan Chen; Fu-An Li; Wei-Cheng Tseng; Yao-Ping Lin; Ruey-Bing Yang et al.
Source: Self-asserted source
Yuh-Charn Lin

SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation

Cardiovascular Research
2024-06-13 | Journal article
DOI: 10.1093/cvr/cvae132
Part of ISSN: 0008-6363
Part of ISSN: 1755-3245
Contributors: Yuh-Charn Lin; Ya-Jen Chang; Shiang-Shin Gau; Chun-Min Lo; Ruey-Bing Yang
Source: Self-asserted source
Yuh-Charn Lin

The biology of SCUBE

Journal of Biomedical Science
2023-05-26 | Journal article
DOI: 10.1186/s12929-023-00925-3
Part of ISSN: 1423-0127
Contributors: Yuh-Charn Lin; Binay K. Sahoo; Shiang-Shin Gau; Ruey-Bing Yang
Source: Self-asserted source
Yuh-Charn Lin

Mechanostimulation-induced integrin αvβ6 and latency associated peptide coupling activates TGF-β and regulates cancer metastasis and stemness

Nano Today
2023-05-19 | Journal article
Contributors: Yuh-Charn Lin
Source: Self-asserted source
Yuh-Charn Lin

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

Haematologica
2022-08-25 | Journal article
DOI: 10.3324/haematol.2022.281151
Part of ISSN: 1592-8721
Part of ISSN: 0390-6078
Contributors: Yuh-Charn Lin
Source: Self-asserted source
Yuh-Charn Lin
grade
Preferred source (of 2)‎

Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

Developmental Cell
2022-06 | Journal article
DOI: 10.1016/j.devcel.2022.06.005
Part of ISSN: 1534-5807
Source: Self-asserted source
Yuh-Charn Lin

Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes

Circulation Research
2022-06-24 | Journal article
DOI: 10.1161/circresaha.121.320301
Part of ISSN: 0009-7330
Part of ISSN: 1524-4571
Source: Self-asserted source
Yuh-Charn Lin

Zebrafish Scube1 and Scube2 cooperate in promoting Vegfa signalling during embryonic vascularization.

Cardiovascular research
2022-03-01 | Journal article
DOI: 10.1093/cvr/cvab125
PMID: 33788916
Source: Self-asserted source
Yuh-Charn Lin

Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats.

Nature biomedical engineering
2021-11-22 | Journal article
DOI: 10.1038/s41551-021-00812-y
PMID: 34811487
Source: Self-asserted source
Yuh-Charn Lin

SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.

American journal of human genetics
2020-12-11 | Journal article
DOI: 10.1016/j.ajhg.2020.11.015
PMID: 33308444
PMC: PMC7820739
Source: Self-asserted source
Yuh-Charn Lin

Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition.

Experimental cell research
2018-07-05 | Journal article
DOI: 10.1016/j.yexcr.2018.07.008
PMID: 29981340
Source: Self-asserted source
Yuh-Charn Lin

PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis.

Nature cell biology
2018-03-28 | Journal article
DOI: 10.1038/s41556-018-0062-y
PMID: 29593326
Source: Self-asserted source
Yuh-Charn Lin

Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis.

Arteriosclerosis, thrombosis, and vascular biology
2018-03-15 | Journal article
DOI: 10.1161/atvbaha.117.310506
PMID: 29545238
Source: Self-asserted source
Yuh-Charn Lin

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation.

Breast cancer research : BCR
2017-10-05 | Journal article
DOI: 10.1186/s13058-017-0904-8
PMID: 28982386
PMC: PMC5629780
Source: Self-asserted source
Yuh-Charn Lin

Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.

Arteriosclerosis, thrombosis, and vascular biology
2016-11-10 | Journal article
DOI: 10.1161/atvbaha.116.308546
PMID: 27834687
Source: Self-asserted source
Yuh-Charn Lin

Disruption of Scube2 Impairs Endochondral Bone Formation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2015-07-01 | Journal article
DOI: 10.1002/jbmr.2451
PMID: 25639508
Source: Self-asserted source
Yuh-Charn Lin

Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures.

The EMBO journal
2014-12-01 | Journal article
DOI: 10.15252/embj.201489652
PMID: 25452496
PMC: PMC4339118
Source: Self-asserted source
Yuh-Charn Lin

Inhibition of the plasma SCUBE1, a novel platelet adhesive protein, protects mice against thrombosis.

Arteriosclerosis, thrombosis, and vascular biology
2014-05-15 | Journal article
DOI: 10.1161/atvbaha.114.303779
PMID: 24833801
Source: Self-asserted source
Yuh-Charn Lin

Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition.

Journal of cell science
2013-11-08 | Journal article
DOI: 10.1242/jcs.132779
PMID: 24213532
Source: Self-asserted source
Yuh-Charn Lin

Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2.

The Journal of biological chemistry
2011-06-07 | Journal article
DOI: 10.1074/jbc.m111.244418
PMID: 21652720
PMC: PMC3143662
Source: Self-asserted source
Yuh-Charn Lin

Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans.

The Biochemical journal
2009-07-29 | Journal article
DOI: 10.1042/bj20090341
PMID: 19480626
Source: Self-asserted source
Yuh-Charn Lin

SCUBE2 suppresses breast tumor cell proliferation and confers a favorable prognosis in invasive breast cancer.

Cancer research
2009-04-01 | Journal article
DOI: 10.1158/0008-5472.can-08-3615
PMID: 19369267
Source: Self-asserted source
Yuh-Charn Lin

Evaluation of antioxidant activity of aqueous extract of some selected nutraceutical herbs

Food Chemistry
2007 | Journal article
DOI: 10.1016/j.foodchem.2007.02.004
Part of ISSN: 0308-8146
Source: Self-asserted source
Yuh-Charn Lin

Molecular action mechanism against apoptosis by aqueous extract from guava budding leaves elucidated with human umbilical vein endothelial cell (HUVEC) model.

Journal of agricultural and food chemistry
2007-09-26 | Journal article
DOI: 10.1021/jf071858b
PMID: 17894456
Source: Self-asserted source
Yuh-Charn Lin

Low-density lipoprotein, collagen, and thrombin models reveal that Rosemarinus officinalis L. exhibits potent antiglycative effects.

Journal of agricultural and food chemistry
2007-03-27 | Journal article
DOI: 10.1021/jf0631833
PMID: 17385882
Source: Self-asserted source
Yuh-Charn Lin

Preventive effects of guava (Psidium guajava L.) leaves and its active compounds against α-dicarbonyl compounds-induced blood coagulation

Food Chemistry
2007-01 | Journal article
DOI: 10.1016/j.foodchem.2006.08.022
Part of ISSN: 0308-8146
Source: Self-asserted source
Yuh-Charn Lin

Kinetic analysis on the sensitivity of glucose- or glyoxal-induced LDL glycation to the inhibitory effect of Psidium guajava extract in a physiomimic system.

Bio Systems
2006-04-28 | Journal article
DOI: 10.1016/j.biosystems.2006.04.004
PMID: 16806668
Source: Self-asserted source
Yuh-Charn Lin

Inhibitory effect of some selected nutraceutic herbs on LDL glycation induced by glucose and glyoxal.

Journal of ethnopharmacology
2005-09-12 | Journal article
DOI: 10.1016/j.jep.2005.06.044
PMID: 16162395
Source: Self-asserted source
Yuh-Charn Lin
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