Personal information

No personal information available

Activities

Collapse all

Works (5)

Discovery of 3-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin derivatives as SARS-CoV-2 main protease inhibitors through virtual screening and biological evaluation

Bioorganic & Medicinal Chemistry Letters
2024-01 | Journal article
DOI: 10.1016/j.bmcl.2023.129547
Contributors: Xiaodong Dou; Qi Sun; Yameng Liu; Yangbin Lu; Caifang Zhang; Guofeng Xu; Yue Xu; Tongyu Huo; Xinyi Zhao; Lingyu Su et al.
Source: check_circle
Crossref

Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins

Nature Communications
2023-08-25 | Journal article
DOI: 10.1038/s41467-023-41018-x
Contributors: Wenzhe Liu; Limin Chen; Dongbao Yin; Zhiheng Yang; Jianfei Feng; Qi Sun; Luhua Lai; Xuefeng Guo
Source: check_circle
Crossref

Discovery of novel SARS-CoV-2 3CL protease covalent inhibitors using deep learning-based screen

European Journal of Medicinal Chemistry
2022-12 | Journal article
DOI: 10.1016/j.ejmech.2022.114803
Contributors: Liying Wang; Zhongtian Yu; Shiwei Wang; Zheng Guo; Qi Sun; Luhua Lai
Source: check_circle
Crossref

Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease

Signal Transduction and Targeted Therapy
2021-05-29 | Journal article
DOI: 10.1038/s41392-021-00628-x
Contributors: Qi Sun; Fei Ye; Hao Liang; Hongbo Liu; Chunmei Li; Roujian Lu; Baoying Huang; Li Zhao; Wenjie Tan; Luhua Lai
Source: check_circle
Crossref

A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2

2020-08-28 | Preprint
DOI: 10.1101/2020.08.28.271569
Contributors: Shiwei Wang; Qi Sun; Youjun Xu; Jianfeng Pei; Luhua Lai
Source: check_circle
Crossref

Peer review (3 reviews for 1 publication/grant)

Review activity for Journal of medicinal chemistry. (3)
How many people are using ORCID?