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Neurodegenerative diseases, Molecular imaging, PET/CT, Drug Discovery, Molecular Pharmacology, Alzheimer's disease, Parkinson‘s disease, Huntington's Disease, Mitochondria, ROS, Electron Transport Pathway, PTP

Activities

Employment (2)

Lanzhou University: Lanzhou, Gansu , CN

2017-07-01 to present | Lecturer (School of Pharmcy)
Employment
Source: Self-asserted source
Yan Liu

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital: Charlestown, MA, US

2020-01-01 to 2023-06-30 | Research Fellow (Radioloy)
Employment
Source: Self-asserted source
Yan Liu

Education and qualifications (2)

Lanzhou University: Lanzhou, Gansu, CN

2011-09-01 to 2017-06-30 | Ph.D (College of Chemistry and Chemical Engineering)
Education
Source: Self-asserted source
Yan Liu

Central South University: Changsha, Hunan, CN

2007-09-01 to 2011-06-30 | Bachelor (School of Pharmcy)
Education
Source: Self-asserted source
Yan Liu

Works (25)

Development and Characterization of a Novel Carbon-11 Labeled Positron Emission Tomography Radiotracer for Neuroimaging of Sirtuin 1 with Benzoxazine-Based Compounds

Drug Design, Development and Therapy
2024-03 | Journal article
Contributors: Yanli Wang; Yan Liu; Yongle Wang; Ping Bai; Madelyn Rose Hallisey; Breanna Varela; Anne Siewko; Changning Wang; Yulong Xu
Source: check_circle
Crossref

Synthesis and Characterization of a New Carbon-11 Labeled Positron Emission Tomography Radiotracer for Orexin 2 Receptors Neuroimaging

Drug Design, Development and Therapy
2024-01 | Journal article
Contributors: Yanli Wang; Yongle Wang; Yan Liu; Hua Cheng; Tewodros Mulugeta Dagnew; Yulong Xu; Changning Wang
Source: check_circle
Crossref

Apply Anticoagulants after Discharge not Benefit to the Incidence of Symptomatic Thrombus in High‐Altitude Areas: A Retrospective Study

Orthopaedic Surgery
2023-10-12 | Journal article | Author
Part of ISSN: 1757-7861
Contributors: xiangji dang; Zhilong Liu; Xiaoyun Sheng; Yan Liu
Source: Self-asserted source
Yan Liu via Crossref Metadata Search
grade
Preferred source (of 2)‎

Foramen lacerum impingement of trigeminal nerve root as a rodent model for trigeminal neuralgia

JCI Insight
2023-06-08 | Journal article | Author
Part of ISSN: 2379-3708
Contributors: Weihua Ding; Liuyue Yang; Qian Chen; Kun Hu; Yan Liu; Eric Bao; Changning Wang; Jianren Mao; Shiqian Shen
Source: Self-asserted source
Yan Liu via Crossref Metadata Search
grade
Preferred source (of 2)‎

Rose essential oil diminishes dopaminergic neuron degenerations and reduces α‐synuclein aggregation in <scp> <i>Caenorhabditis elegans</i> </scp> models of Parkinson's disease

Phytotherapy Research
2023-03-15 | Journal article | Author
Part of ISSN: 0951-418X
Part of ISSN: 1099-1573
Contributors: Muhammad Fahim; Yan Liu; Ningbo Wang; Longhe Zhao; Yangtao Zhou; Hui Yang; Hongyu Li
Source: Self-asserted source
Yan Liu

Medial Patellofemoral Ligament Reconstruction is Preferred to Repair or Reefing for First-Time Patellar Dislocation: A Systematic Review and Meta-analysis

Indian Journal of Orthopaedics
2023-02 | Journal article
Part of ISSN: 0019-5413
Part of ISSN: 1998-3727
Contributors: Jin Jiang; Zhi Yi; Junmin Li; Yan Liu; Yayi Xia; Meng Wu
Source: Self-asserted source
Yan Liu

Noninvasive Positron Emission Tomography Imaging of SIRT1 in a Model of Early-Stage Alcoholic Liver Disease

Molecular Pharmaceutics
2023-02-24 | Journal article
Part of ISSN: 1543-8384
Part of ISSN: 1543-8392
Contributors: Yan Liu; Zude Chen; Yanli Wang; Madelyn Rose Hallisey; Breanna Lizeth Varela; Anne Siewko; Darcy Tocci; Changning Wang; Yulong Xu
Source: Self-asserted source
Yan Liu

A positron emission tomography imaging probe selectively targeting the BD1 bromodomain and extra-terminal domain

Chemical Communications
2022 | Journal article
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Contributors: Ping Bai; Liu Yan; Frederick A. Bagdasarian; Moses Q. Wilks; Hsiao-Ying Wey; Changning Wang
Source: Self-asserted source
Yan Liu

Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson’s disease

NeuroToxicology
2022-12 | Journal article
Part of ISSN: 0161-813X
Contributors: Fahim Muhammad; Yan Liu; Ningbo Wang; Longhe Zhao; Yangtao Zhou; Hui Yang; Hongyu Li
Source: Self-asserted source
Yan Liu

Black mulberry (Morus nigra) fruit extract alleviated AD-Like symptoms induced by toxic Aβ protein in transgenic Caenorhabditis elegans via insulin DAF-16 signaling pathway

Food Research International
2022-10 | Journal article | Author
Part of ISSN: 0963-9969
Contributors: Enhui Wang; Ningbo Wang; Yue Zou; Muhammad Fahim; Yongtao Zhou; Hui Yang; Yan Liu; Hongyu Li
Source: Self-asserted source
Yan Liu

Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease

Acta Pharmaceutica Sinica B
2022-10 | Journal article
Part of ISSN: 2211-3835
Contributors: Ping Bai; Prasenjit Mondal; Frederick Bagdasarian; Nisha Rani; Yan Liu; Ashley Gomm; Darcy R. Tocci; Se Hoon Choi; Hsiao-Ying Wey; Rudolph E. Tanzi et al.
Source: Self-asserted source
Yan Liu

Synthesis and characterization of a new Positron emission tomography probe for orexin 2 receptors neuroimaging

Bioorganic Chemistry
2022-06 | Journal article | Author
Part of ISSN: 0045-2068
Contributors: Ping Bai; Yan Liu; Yulong Xu; Robin Striar; Gengyang Yuan; Sepideh Afshar; Amelia G. Langan; Anna K. Rattray; Changning Wang
Source: Self-asserted source
Yan Liu

Preliminary studies of an imidazole-based alcohol derivative for imaging of Heme oxygenase 1

Bioorganic &amp; Medicinal Chemistry Letters
2022-05 | Journal article
Part of ISSN: 0960-894X
Contributors: Yulong Xu; Yan Liu; Robin Striar; Amelia Langan; Anna Kate Rattray; Sepideh Afshar; Changning Wang
Source: Self-asserted source
Yan Liu

Antioxidative role of Traditional Chinese Medicine in Parkinson's disease

Journal of Ethnopharmacology
2022-03 | Journal article
Part of ISSN: 0378-8741
Contributors: Fahim Muhammad; Yan Liu; Yongtao Zhou; Hui Yang; Hongyu Li
Source: Self-asserted source
Yan Liu

Anti-α-synuclein Toxicity and Anti-neurodegenerative Role of Chrysin in Transgenic <i>Caenorhabditis elegans</i> Models of Parkinson’s Disease

ACS Chemical Neuroscience
2022-02-16 | Journal article
Part of ISSN: 1948-7193
Part of ISSN: 1948-7193
Contributors: Muhammad Fahim; Yan Liu; Ningbo Wang; Longhe Zhao; Yongtao Zhou; Hui Yang; Hongyu Li
Source: Self-asserted source
Yan Liu
grade
Preferred source (of 2)‎

Novel Positron Emission Tomography Radiotracers for Imaging Mitochondrial Complex I

ACS Chemical Neuroscience
2021-12-15 | Journal article
Part of ISSN: 1948-7193
Part of ISSN: 1948-7193
Contributors: Yulong Xu; Yiming Xu; Savannah Biby; Ping Bai; Yan Liu; Can Zhang; Changning Wang; Shijun Zhang
Source: Self-asserted source
Yan Liu

Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by Brain Imaging with Positron Emission Tomography

Journal of Medicinal Chemistry
2021-10-28 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Yu Lan; Ping Bai; Yan Liu; Sepideh Afshar; Robin Striar; Anna Kathryn Rattray; Tyler Nicholas Meyer; Amelia G. Langan; Alisa M. Posner; Shiqian Shen et al.
Source: Self-asserted source
Yan Liu

Design, Synthesis, and Evaluation of Thienodiazepine Derivatives as Positron Emission Tomography Imaging Probes for Bromodomain and Extra-Terminal Domain Family Proteins

Journal of Medicinal Chemistry
2021-10-14 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Ping Bai; Yu Lan; Debasis Patnaik; Hao Wang; Yan Liu; Zude Chen; Gengyang Yuan; Sepideh Afshar; Robin Striar; Julia S. Zagaroli et al.
Source: Self-asserted source
Yan Liu

Synthesis and Characterization of a Positron Emission Tomography Imaging Probe Selectively Targeting the Second Bromodomain of Bromodomain Protein BRD4

Bioconjugate Chemistry
2021-08-18 | Journal article
Part of ISSN: 1043-1802
Part of ISSN: 1520-4812
Contributors: Ping Bai; Yu Lan; Hao Wang; Yan Liu; Robin Striar; Gengyang Yuan; Sepideh Afshar; Julia S. Zagaroli; Darcy R. Tocci; Amelia G. Langan et al.
Source: Self-asserted source
Yan Liu

Gastrodia elata powder capsule enhances anti-epileptic effect of carbamazepine by decreasing P-gp expression

Tropical Journal of Pharmaceutical Research
2021-06-24 | Journal article
Part of ISSN: 1596-9827
Part of ISSN: 1596-5996
Contributors: Xiangji Dang; Pei Zhao; Yan Liu; Long Qin; Haisheng Jiao
Source: Self-asserted source
Yan Liu

Protective effect of Terminalia chebula Retz. extract against Aβ aggregation and Aβ-induced toxicity in Caenorhabditis elegans

Journal of Ethnopharmacology
2021-03 | Journal article
Part of ISSN: 0378-8741
Contributors: longhe zhao; Ziyun Duan; Yu Wang; meizhu wang; Yan Liu; Xin Wang; Hongyu Li
Source: Self-asserted source
Yan Liu

Discovery of carbon-11 labeled sulfonamide derivative: A PET tracer for imaging brain NLRP3 inflammasome

Bioorganic &amp; Medicinal Chemistry Letters
2021-02 | Journal article
Part of ISSN: 0960-894X
Contributors: Yulong Xu; Yiming Xu; Hallie Blevins; Yu Lan; Yan Liu; Gengyang Yuan; Robin Striar; Julia S. Zagaroli; Darcy Tocci ; Amelia G. Langan et al.
Source: Self-asserted source
Yan Liu

Discovery of a Positron Emission Tomography Radiotracer Selectively Targeting the BD1 Bromodomains of BET Proteins

ACS Medicinal Chemistry Letters
2021-02-11 | Journal article
Part of ISSN: 1948-5875
Part of ISSN: 1948-5875
Contributors: Ping Bai; Xiaoxia Lu; Yan Liu; Yu Lan; Hao Wang; STEPHANIE FIEDLER; Robin Striar; Changning Wang
Source: Self-asserted source
Yan Liu

Kushui Rose (R.SetatexR.Rugosa) decoction exerts antitumor effects in C. elegans by downregulating Ras/MAPK pathway and resisting oxidative stress

International Journal of Molecular Medicine
2018-06-21 | Journal article
Part of ISSN: 1107-3756
Part of ISSN: 1791-244X
Contributors: Yan Liu; Dejuan Zhi; Xin Wang; Dongqing Fei; Zhanxin Zhang; Zhengrong Wu; Yang Li; Peng Chen; Hongyu Li
Source: Self-asserted source
Yan Liu

Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by opening mitochondrial permeability transition pore via regulating cyclophilin D

Scientific Reports
2016-12-16 | Journal article
Part of ISSN: 2045-2322
Contributors: Yan Liu; Dejuan Zhi; Menghui Li; Dongling Liu; Xin Wang; Zhengrong Wu; Zhanxin Zhang; Dongqing Fei; Yang Li; Hongmei Zhu et al.
Source: Self-asserted source
Yan Liu

Peer review (6 reviews for 2 publications/grants)

Review activity for Biomedicine & pharmacotherapy. (5)
Review activity for International journal of obesity. (1)