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Pitt ID: DLC7

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Employment (2)

University of Pittsburgh: Pittsburgh, PA, US

Employment
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University of Pittsburgh

Columbia University Medical Center: New York, NY, US

1993-12 to 1998-11 | Post Doctoral Associate (Genetics & Development)
Employment
Source: Self-asserted source
Deborah Chapman

Education and qualifications (2)

Columbia University Medical Center: New York, NY, US

1988-08 to 1993-11 | PhD (Genetics & Development)
Education
Source: Self-asserted source
Deborah Chapman

Wesleyan University: Middletown, CT, US

1984-08 to 1988-05 | BA (Molecular Biology & Biochemistry)
Education
Source: Self-asserted source
Deborah Chapman

Works (32)

Ectopic expression of T in the paraxial mesoderm disrupts somite maturation in the mouse

Developmental Biology
2022-05 | Journal article
DOI: 10.1016/j.ydbio.2022.02.010
Contributors: Gregory P. Campbell; Deborah R. Farkas; Deborah L. Chapman
Source: check_circle
Crossref

Functionally distinct roles for T and Tbx6 during mouse development

Biology Open
2020-08-15 | Journal article
DOI: 10.1242/bio.054692
Contributors: Amy K. Wehn; Deborah R. Farkas; Carly E. Sedlock; Dibya Subedi; Deborah L. Chapman
Source: check_circle
Crossref

Impaired intermediate formation in mouse embryos expressing reduced levels of Tbx6

genesis
2019-03 | Journal article
DOI: 10.1002/dvg.23270
Contributors: Deborah L. Chapman
Source: check_circle
Crossref

TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling

Nature
2016-10 | Journal article
DOI: 10.1038/nature20095
Part of ISSN: 0028-0836
Contributors: Hai-Qiang Dai; Bang-An Wang; Lu Yang; Jia-Jia Chen; Guo-Chun Zhu; Mei-Ling Sun; Hao Ge; Rui Wang; Deborah L. Chapman; Fuchou Tang et al.
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Autosomal dominant spondylocostal dysostosis is caused by mutation in TBX6.

Human molecular genetics
2013-04 | Journal article
DOI: 10.1093/hmg/ddt012
PMID: 23335591
Contributors: Sparrow DB; McInerney-Leo A; Gucev ZS; Gardiner B; Marshall M; Leo PJ; Chapman DL; Tasic V; Shishko A; Brown MA et al.
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program.

Nature communications
2011-07 | Journal article
DOI: 10.1038/ncomms1381
PMID: 21750544
PMC: PMC3622708
Contributors: Chalamalasetty RB; Dunty WC; Biris KK; Ajima R; Iacovino M; Beisaw A; Feigenbaum L; Chapman DL; Yoon JK; Kyba M et al.
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Tbx18 and Tbx15 null-like phenotypes in mouse embryos expressing Tbx6 in somitic and lateral plate mesoderm

Developmental Biology
2010-11 | Journal article
DOI: 10.1016/j.ydbio.2010.09.001
Part of ISSN: 0012-1606
Contributors: Amy K. Wehn; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Kinked tailmutation results in notochord defects in heterozygotes and distal visceral endoderm defects in homozygotes

Developmental Dynamics
2009 | Journal article
DOI: 10.1002/dvdy.22141
Part of ISSN: 1058-8388
Contributors: Deborah R. Farkas; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Generation of transgenic mice expressing Cre recombinase under the control of theDll1mesoderm enhancer element

genesis
2009-05 | Journal article
DOI: 10.1002/dvg.20503
Part of ISSN: 1526-954X
Contributors: Amy K. Wehn; Phillip H. Gallo; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis.

Development (Cambridge, England)
2008-08 | Journal article
DOI: 10.1242/dev.019877
PMID: 18579680
Contributors: Oginuma M; Niwa Y; Chapman DL; Saga Y
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Role of T and Tbx6 in mesodermal patterning

Developmental Biology
2008-07 | Journal article
DOI: 10.1016/j.ydbio.2008.05.511
Part of ISSN: 0012-1606
Contributors: Amy K. Wehn; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Paraxial mesoderm signals are required for intermediate mesoderm formation in the mouse

Developmental Biology
2006-07 | Journal article
DOI: 10.1016/j.ydbio.2006.04.206
Part of ISSN: 0012-1606
Contributors: Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Dll1 is a downstream target of Tbx6 in the paraxial mesoderm

genesis
2005 | Journal article
DOI: 10.1002/gene.20140
Part of ISSN: 1526-954X
Contributors: Phillip H. White; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Regulation ofTbx6 expression by Notch signaling

genesis
2005 | Journal article
DOI: 10.1002/gene.20124
Part of ISSN: 1526-954X
Contributors: Phillip H. White; Deborah R. Farkas; Deborah L. Chapman
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

THE NEURAL TUBE PATTERNS VESSELS DEVELOPMENTALLY USING THE VEGF SIGNALING PATHWAY

Cardiovascular Pathology
2004-05 | Journal article
DOI: 10.1016/j.carpath.2004.03.193
Part of ISSN: 1054-8807
Contributors: Kelly A Hogan; Carrie A Ambler; Deborah L Chapman; Victoria L Bautch
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

The neural tube patterns vessels developmentally using the VEGF signaling pathway.

Development (Cambridge, England)
2004-04 | Journal article
DOI: 10.1242/dev.01039
PMID: 14998923
Contributors: Hogan KA; Ambler CA; Chapman DL; Bautch VL
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Critical role for Tbx6 in mesoderm specification in the mouse embryo

Mechanisms of Development
2003-07 | Journal article
DOI: 10.1016/s0925-4773(03)00066-2
Part of ISSN: 0925-4773
Contributors: Deborah L Chapman; Amalene Cooper-Morgan; Zachary Harrelson; Virginia E Papaioannou
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Defective somite patterning in mouse embryos with reduced levels of Tbx6.

Development (Cambridge, England)
2003-04 | Journal article
DOI: 10.1242/dev.00367
PMID: 12620991
Contributors: White PH; Farkas DR; McFadden EE; Chapman DL
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.

The Journal of biological chemistry
2002-12 | Journal article
DOI: 10.1074/jbc.m206858200
PMID: 12376544
Contributors: Maeda T; Chapman DL; Stewart AF
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6

Nature
1998-02 | Journal article
DOI: 10.1038/35624
Part of ISSN: 0028-0836
Contributors: Deborah L. Chapman; Virginia E. Papaioannou
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.

Genes & development
1997-05 | Journal article
DOI: 10.1101/gad.11.10.1226
PMID: 9171368
Contributors: Ludwig T; Chapman DL; Papaioannou VE; Efstratiadis A
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Tbx6,a Mouse T-Box Gene Implicated in Paraxial Mesoderm Formation at Gastrulation

Developmental Biology
1996 | Journal article
DOI: 10.1006/dbio.1996.0326
Part of ISSN: 0012-1606
Contributors: Deborah L. Chapman; Irina Agulnik; Sarah Hancock; Lee M. Silver; Virginia E. Papaioannou
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Evolution of mouse T-box genes by tandem duplication and cluster dispersion.

Genetics
1996-09 | Journal article
PMID: 8878690
PMC: PMC1207498
Contributors: Agulnik SI; Garvey N; Hancock S; Ruvinsky I; Chapman DL; Agulnik I; Bollag R; Papaioannou V; Silver LM
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.

Developmental dynamics : an official publication of the American Association of Anatomists
1996-08 | Journal article
DOI: 10.1002/(sici)1097-0177(199608)206:4<379::aid-aja4>3.0.co;2-f
PMID: 8853987
Contributors: Chapman DL; Garvey N; Hancock S; Alexiou M; Agulnik SI; Gibson-Brown JJ; Cebra-Thomas J; Bollag RJ; Silver LM; Papaioannou VE
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity.

Mechanisms of development
1996-05 | Journal article
DOI: 10.1016/0925-4773(96)00514-x
PMID: 8798150
Contributors: Gibson-Brown JJ; Agulnik SI; Chapman DL; Alexiou M; Garvey N; Silver LM; Papaioannou VE
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Programmed cell death in the absence of c-Fos and c-Jun.

Development (Cambridge, England)
1996-01 | Journal article
PMID: 8565820
Contributors: Roffler-Tarlov S; Brown JJ; Tarlov E; Stolarov J; Chapman DL; Alexiou M; Papaioannou VE
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.

Nature genetics
1995-10 | Journal article
DOI: 10.1038/ng1095-155
PMID: 7550343
Contributors: Zeitlin S; Liu JP; Chapman DL; Papaioannou VE; Efstratiadis A
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Expression and Function of Protein Kinases During Mammalian Gametogenesis

Advances in Developmental Biochemistry
1994 | Other
DOI: 10.1016/s1064-2722(08)60005-5
Part of ISBN: 9781559388658
Part of ISSN: 1064-2722
Contributors: Deborah L. Chapman; Debra J. Wolgemuth
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Regulation of M-Phase Promoting Factor Activity during Development of Mouse Male Germ Cells

Developmental Biology
1994-10 | Journal article
DOI: 10.1006/dbio.1994.1270
Part of ISSN: 0012-1606
Contributors: Deborah L. Chapman; Debra J. Wolgemuth
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search

Expression of proliferating cell nuclear antigen in the mouse germ line and surrounding somatic cells suggests both proliferation-dependent and -independent modes of function.

The International journal of developmental biology
1994-09 | Journal article
PMID: 7848832
Contributors: Chapman DL; Wolgemuth DJ
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Isolation of the murine cyclin B2 cDNA and characterization of the lineage and temporal specificity of expression of the B1 and B2 cyclins during oogenesis, spermatogenesis and early embryogenesis.

Development (Cambridge, England)
1993-05 | Journal article
PMID: 8375336
Contributors: Chapman DL; Wolgemuth DJ
Source: Self-asserted source
Deborah Chapman via Europe PubMed Central

Identification of a mouse B-type cyclin which exhibits developmentally regulated expression in the germ line

Molecular Reproduction and Development
1992-11 | Journal article
DOI: 10.1002/mrd.1080330305
Part of ISSN: 1040-452X
Contributors: Deborah L. Chapman; Debra J. Wolgemuth
Source: Self-asserted source
Deborah Chapman via Crossref Metadata Search
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