Bhaja Krushna Padhi (0000-0002-8705-9173)

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Biography

Bhaja K Padhi, Ph.D., DABT, is a Biologist at the Hazard Identification Division in Environmental Health Science and Research Bureau, Health Canada, Ottawa, Canada. As a Diplomate of the American Board of Toxicology since 2014, Dr. Padhi's expertise in the field is apparent from his original research published in various journals, including Nature, Regulatory Toxicology and Pharmacology, Neurotoxicology, Toxicology Letters, and Analytical Biochemistry. During his research career, Dr. Padhi worked at various science institutions in Canada, India, and the USA and used different in vitro and in vivo model systems (e.g., neuronal cells, rats, and zebrafish) and methods (e.g., genomics, molecular biology, and bioinformatics) for genetics, genomics and toxicological research. He conducted post-doctoral research at Ottawa Health Research Institute, University of Ottawa, Ottawa. He secured a "Certificate in Bioinformatics" accredited by the University of British Columbia, Vancouver, and worked as a Visiting Scientist at Johns Hopkins University, Baltimore, Maryland, USA. Padhi is a member of various professional societies, including the Society of Toxicology, USA, the International Neurotoxicology Association, the Netherlands, and a research manuscript reviewer of several international journals. As a member of the Discovery Grant's Evaluation Group for Genes, Cells, and Molecules (2023-2026) within the Natural Sciences and Engineering Research Council of Canada (NSERC), he reviews research proposals of scientists across Canada for funding decisions. Dr. Padhi is a planning and steering committee member (2016- present) of the Health Canada Science Forum (HCSF), an annual event showcasing Health Canada's science. He has been instrumental in organizing and chairing scientific sessions, reviewing research abstracts and co-chairing the poster competition award sub-committee. His leadership in these roles has influenced HCSF's impact on the Health Canada community.

https://profils-profiles.science.gc.ca/en/profile/bhaja-k-padhi-phd-dabt

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Health Canada: Ottawa, ON, CA

2004-10-01 to present | Research Biologist (Environmental Health Science and Research Bureau)

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Bhaja Krushna Padhi

https://orcid.org/0000-0002-8705-9173

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Biography

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Employment (1)

Health Canada: Ottawa, ON, CA

Education and qualifications (1)

Ottawa Hospital Research Institute: Ottawa, ON, CA

Professional activities (4)

Society of Toxicology: Reston, VA, US

Natural Sciences and Engineering Research Council: Ottawa, Please Select..., CA

American College of Toxicology: Reston, VA, US

American Board of Toxicology, Inc.: Raleigh, NC, US

Works (27)

Developing messenger RNA biomarkers: A workflow to characterise and identify transcript target sequences unaffected by alternative splicing for reproducible gene transcript quantification by reverse transcriptase quantitative polymerase chain reaction

A bioinformatics framework for targeted gene expression assay design: Application to in vitro developmental neurotoxicity screening in a rat model

Characterization of the rat Acetylcholinesterase readthrough (AChE-R) splice variant: Implications for toxicological studies

A bioinformatics workflow for the evaluation of RT-qPCR primer specificity: Application for the assessment of gene expression data reliability in toxicological studies

A PCR-based quantitative assay for the evaluation of mRNA integrity in rat samples

Characterization of the pro-inflammatory potencies of purified Jatropha phorbol esters by a gene expression-based in vitro bioassay

A PCR-based approach to assess genomic DNA contamination in RNA: Application to rat RNA samples

Cyclooxygenase 1 mRNA expression is undetectable in Madin Darby Canine Kidney cells

Development of a sensitive in vitro assay to quantify the biological activity of pro-inflammatory phorbol esters in Jatropha oil

Perinatal methylmercury exposure perturbs the expression of Plp1 and Cnp splice variants in cerebellum of rat pups

Expression pattern of an evolutionarily conserved splice variant in the ratTacc2gene

Perturbation of Myelin basic protein (Mbp) splice variant expression in developing rat cerebellum following perinatal exposure to methylmercury

Loss of fish actinotrichia proteins and the fin-to-limb transition

Gene expression profiling in rat cerebellum following in utero and lactational exposure to mixtures of methylmercury, polychlorinated biphenyls and organochlorine pesticides

Genetic variation in ecoraces of tropical tasar silkworm, Antheraea mylitta D. using RFLF technique

Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblast differentiation and function

Independent expansion of the keratin gene family in teleostean fish and mammals: An insight from phylogenetic analysis and radiation hybrid mapping of keratin genes in zebrafish

Screen for genes differentially expressed during regeneration of the zebrafish caudal fin

Co-amplification of dhfr and a homologue of hmsh3 in a Chinese hamster methotrexate-resistant cell line correlates with resistance to a range of chemotherapeutic drugs

Characterization of MboI satellites in Cirrhina mrigala and Clarias batrachus (Pisces)

Inadvertent hybridization in a carp hatchery as detected by nuclear DNA RFLP

Inadvertent hybridization in a carp hatchery as detected by nuclear DNA RFLP

Fishery genetics: An emerging discipline

Xanthine dehydrogenase isozymes in twenty species of teleostean fishes: Tissue distribution and possible taxonomic significance

LACTATE DEHYDROGENASE IN THE GRASS CARP CTENOPIIARYNGODON IDELLA (PISCES)

Lactate dehydrogenase isozymes in fifty-two species of teleostean fishes: Taxonomic significance of Ldh-C gene expression

MULTIPLE XANTHINE DEHYDROGENASE ISOZYMES IN THE EXOTIC CARP CTENOPHARYNGODON IDELLA (CYPRIMDAE: PISCES)

Peer review (20 reviews for 6 publications/grants)