K Löbmann (0000-0002-8710-6347)

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Biography

Korbinian Löbmann received his PhD degree from the University of Otago, Dunedin, New Zealand in 2013. His thesis with the title ‘Co-amorphous drug formulations’ was put on the Health Sciences Divisional List of Exceptional PhD theses based on the research content, originality, quality of expression, and accuracy of presentation. After his PhD he was appointed as Assistant Professor at the Department of Pharmacy, University of Copenhagen, Denmark and obtained a position as Associate Professor in April 2017. In 2019, he co-founded the company Zerion Pharma as a spinout from the University of Copenhagen, where he is since working was Chief Scientific Officer. His research interests are in formulation and physical characterization of solid drug delivery systems and in particular the development of oral drug delivery systems for poorly water soluble drugs.

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Zerion Pharma A/S: Birkeroed, DK

2019-01-01 to present | Chief Scientific Officer

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K Löbmann

https://orcid.org/0000-0002-8710-6347

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Biography

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Employment (3)

Zerion Pharma A/S: Birkeroed, DK

University of Copenhagen: Copenhagen, DK

University of Copenhagen: Copenhagen, DK

Education and qualifications (3)

University of Otago: Dunedin, NZ

Ludwig-Maximilians-Universitat Munchen: Munchen, Bayern, DE

University of Otago: Dunedin, NZ

Professional activities (1)

European Federation for Pharmaceutical Sciences (EUFEPS): Stockholm, SE

Works (50 of 114)

Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

Mechanisms of Drug Solubility Enhancement Induced by β-Lactoglobulin-Based Amorphous Solid Dispersions

Protein Based Amorphous Solid Dispersion: a Case Study Investigating Different Whey Proteins at High Drug Loading

A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms

Microwave-Induced in Situ Drug Amorphization Using a Mixture of Polyethylene Glycol and Polyvinylpyrrolidone

The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization

The Influence of Drug–Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

Studying the Impact of the Temperature and Sorbed Water during Microwave-Induced In Situ Amorphization: A Case Study of Celecoxib and Polyvinylpyrrolidone

Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies

Deliquescence Behavior of Deep Eutectic Solvents

Constraints on CaCO<inf>3</inf> precipitation in superabsorbent polymer by aerobic bacteria

Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

The influence of drug and polymer particle size on the in situ amorphization using microwave irradiation

The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib

Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions

Hot Melt Coating of Amorphous Carvedilol

Influence of the Polymer Glass Transition Temperature and Molecular Weight on Drug Amorphization Kinetics Using Ball Milling

Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization

Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

Dipeptides as co-formers in co-amorphous systems

Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency

Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions

Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity

Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

Whey proteins as stabilizers in amorphous solid dispersions

Direct Measurement of Amorphous Solubility

In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium

Co-former selection for co-amorphous drug-amino acid formulations

Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study

In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

Special issue on “Formulation strategies and manufacturing technologies to enhance non-invasive drug delivery”

Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions

Aspartame as a co-former in co-amorphous systems

Organic acids as co-formers for co-amorphous systems – Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

The Role of Glass Transition Temperatures in Coamorphous Drug–Amino Acid Formulations

A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica

Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase

Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l-Arginine

Peer review (7 reviews for 1 publication/grant)