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Scopus Author ID: 6701709097

Keywords

Ageing Lifespan Metabolism Mitochondria Caloric restriction Frailty

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United Kingdom

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Funding (13)

Developing an evolutionary model for metabolic syndrome: understanding energy sparing adaptations in geothermal populations of stickleback

2022-02-01 to 2026-01-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9849375
GRANT_NUMBER: BB/W002515/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

Does the parasitic worm product ES-62 resolve aberrant chronic inflammation by sensing and normalising the gut microbiome and intestinal integrity?

2021-05-09 to 2024-05-08 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9472332
GRANT_NUMBER: BB/V001027/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

How does the immunomodulatory parasitic worm product ES-62 rewire bone marrow cells to increase healthspan and lifespan in obesity-accelerated ageing?

2021-05-09 to 2024-05-08 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.9727214
GRANT_NUMBER: MR/V000683/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

Australia Partnering Award: Collaborating to better understand metabolism and ageing across model organisms

2020-06-30 to 2023-06-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9054827
GRANT_NUMBER: BB/T018607/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

RNA Polymerase III in healthy ageing: consolidating the mechanisms of longevity from worms and flies to mice

2019-09-30 to 2023-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.8470135
GRANT_NUMBER: BB/S014330/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

Mechanisms of insulin resistance in South Asians (MIRSA): the roles of skeletal muscle microvasculature and mitochondrial metabolism

2019-07-31 to 2023-01-31 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.8673792
GRANT_NUMBER: MR/R023247/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

Why do fish fail at high temperatures?

2018-02-05 to 2021-08-03 | Grant
Natural Environment Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.6945561
GRANT_NUMBER: NE/R001510/1
Source: Self-asserted source
Colin Selman via DimensionsWizard

Gene editing for therapeutic sulphide elevation to reverse accelerated ageing in vivo

2017-10-30 to 2021-10-29 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.7156336
GRANT_NUMBER: 1952199
Source: Self-asserted source
Colin Selman via DimensionsWizard

Can studying the mechanism of action of the parasitic worm-derived immunomodulator ES-62, inform on how to slow ageing and improve healthspan?

Source: Self-asserted source
Colin Selman via DimensionsWizard

Androgens: unlocking the key drivers of male health and wellbeing

Source: Self-asserted source
Colin Selman via DimensionsWizard

Dissecting the mechanisms underlying lifespan extension in insulin signalling mutant mice

Source: Self-asserted source
Colin Selman via DimensionsWizard

Effect of Inorganic Nitrite on Cardiac and Skeletal Muscle: Physiology, Pharmacology and Therapeutic Potential

Source: Self-asserted source
Colin Selman via DimensionsWizard

Dissecting the mechanisms underlying lifespan extension in insulin signalling mutant mice

Source: Self-asserted source
Colin Selman via DimensionsWizard

Works (50 of 112)

Items per page:
Page 1 of 3

Parallel adaptation to geothermally-warmed habitats due to common structural variation and functional developmental pathways

2025-02-20 | Preprint
DOI: 10.1101/2025.02.17.638600
Contributors: Matthew K. Brachmann; Ana P. B. Costa; Shaun Robertson; Kate Donoghue; Natalie Pilakouta; Mark Whitehead; Xuan Liu; Bjarni Kristjansson; Skuli Skulason; Colin Selman et al.
Source: check_circle
Crossref

Overlooked histories in ageing research: Pioneering women at the foundation of our field

Aging Cell
2024-12 | Journal article
DOI: 10.1111/acel.14432
Contributors: Marina Ezcurra; Colin Selman; Jennifer Tullet; Nathan Woodling
Source: check_circle
Crossref

The dietary exposome: a brief history of diet, longevity, and age-related health in rodents

Clinical Science
2024-11-06 | Journal article
DOI: 10.1042/CS20241248
Contributors: Colin Selman
Source: check_circle
Crossref

Timing of TORC1 inhibition dictates Pol III involvement inCaenorhabditis eleganslongevity

Life Science Alliance
2024-07 | Journal article
DOI: 10.26508/lsa.202402735
Contributors: Yasir Malik; Isabel Goncalves Silva; Rene Rivera Diazgranados; Colin Selman; Nazif Alic; Jennifer MA Tullet
Source: check_circle
Crossref

Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan

Aging Cell
2024-05 | Journal article
DOI: 10.1111/acel.14141
Contributors: Gillian Borland; Stephen E. Wilkie; Jackie Thomson; Zhe Wang; Jennifer M. A. Tullet; Nazif Alic; Colin Selman
Source: check_circle
Crossref

Can exercise prevent the age‐related decline in adaptive homeostasis? Evidence across organisms and tissues

The Journal of Physiology
2023-06 | Journal article
DOI: 10.1113/JP284583
Contributors: Karyn L. Hamilton; Colin Selman
Source: check_circle
Crossref

Mendelian randomization analyses implicate biogenesis of translation machinery in human aging

Genome Research
2022-02 | Journal article
DOI: 10.1101/gr.275636.121
Contributors: Sara Javidnia; Stephen Cranwell; Stefanie H. Mueller; Colin Selman; Jennifer M.A. Tullet; Karoline Kuchenbaecker; Nazif Alic
Source: check_circle
Crossref

Hydrogen sulfide in ageing, longevity and disease.

The Biochemical journal
2021-10 | Journal article
DOI: 10.1042/bcj20210517
PMID: 34613340
Contributors: Wilkie SE; Borland G; Carter RN; Morton NM; Selman C
Source: Self-asserted source
Colin Selman via Europe PubMed Central
grade
Preferred source (of 2)‎

Corrigendum: RNA Polymerase III, Ageing and Longevity.

Frontiers in genetics
2021-09 | Journal article
DOI: 10.3389/fgene.2021.758135
PMID: 34539762
PMC: PMC8444630
Contributors: Kulaberoglu Y; Malik Y; Borland G; Selman C; Alic N; Tullet JMA
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Growth acceleration results in faster telomere shortening later in life.

Proceedings. Biological sciences
2021-08 | Journal article
DOI: 10.1098/rspb.2021.1118
PMID: 34375555
Contributors: Salmón P; Millet C; Selman C; Monaghan P
Source: Self-asserted source
Colin Selman via Europe PubMed Central
grade
Preferred source (of 2)‎

RNA Polymerase III, Ageing and Longevity.

Frontiers in genetics
2021-07 | Journal article
DOI: 10.3389/fgene.2021.705122
PMID: 34295356
PMC: PMC8290157
Contributors: Kulaberoglu Y; Malik Y; Borland G; Selman C; Alic N; Tullet JMA
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice.

Molecular and cellular endocrinology
2021-07 | Journal article
DOI: 10.1016/j.mce.2021.111376
PMID: 34246728
PMC: PMC8417819
Contributors: Mulvey L; Wilkie SE; Borland G; Griffiths K; Sinclair A; McGuinness D; Watson DG; Selman C
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Metabolic rate through the life-course: From the organism to the organelle.

Experimental gerontology
2020-08 | Journal article
DOI: 10.1016/j.exger.2020.111059
PMID: 32853835
Contributors: Seo AY; Speakman JR; Selman C
Source: Self-asserted source
Colin Selman via Europe PubMed Central

The hepatic compensatory response to elevated systemic sulfide promotes diabetes

2020-04 | Preprint
DOI: 10.1101/2020.04.27.064287
PPR: PPR156257
Contributors: Carter RN; Gibbins MT; Barrios-Llerena ME; Wilkie SE; Freddolino PL; Libiad M; Vitvitsky V; Emerson B; Bihan TL; Brice M et al.
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Photoperiodic regulation in a wild-derived mouse strain.

The Journal of experimental biology
2020-03 | Journal article
DOI: 10.1242/jeb.217687
PMID: 32098881
Contributors: Sáenz de Miera C; Beymer M; Routledge K; Król E; Selman C; Hazlerigg DG; Simonneaux V
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice.

GeroScience
2020-03 | Journal article
DOI: 10.1007/s11357-020-00168-2
PMID: 32162209
PMC: PMC7205779
Contributors: Wilkie SE; Mulvey L; Sands WA; Marcu DE; Carter RN; Morton NM; Hine C; Mitchell JR; Selman C
Source: Self-asserted source
Colin Selman via Europe PubMed Central
grade
Preferred source (of 2)‎

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.

PLoS pathogens
2020-03 | Journal article
DOI: 10.1371/journal.ppat.1008391
PMID: 32163524
PMC: PMC7108737
Contributors: Crowe J; Lumb FE; Doonan J; Broussard M; Tarafdar A; Pineda MA; Landabaso C; Mulvey L; Hoskisson PA; Babayan SA et al.
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Measurement of mitochondrial respiration in permeabilized fish gills.

The Journal of experimental biology
2020-02 | Journal article
DOI: 10.1242/jeb.216762
PMID: 31974221
PMC: PMC7044462
Contributors: Dawson NJ; Millet C; Selman C; Metcalfe NB
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model.

Molecular and biochemical parasitology
2019-10 | Journal article
DOI: 10.1016/j.molbiopara.2019.111232
PMID: 31634505
Contributors: Lumb FE; Crowe J; Doonan J; Suckling CJ; Selman C; Harnett MM; Harnett W
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Dietary restriction in ILSXISS mice is associated with widespread changes in splicing regulatory factor expression levels.

Experimental gerontology
2019-09 | Journal article
DOI: 10.1016/j.exger.2019.110736
PMID: 31521722
Contributors: Lee BP; Mulvey L; Barr G; Garratt J; Goodman E; Selman C; Harries LW
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Allostatic load and ageing: linking the microbiome and nutrition with age-related health.

Biochemical Society transactions
2019-08 | Journal article
DOI: 10.1042/bst20190110
PMID: 31416886
Contributors: Shiels PG; Buchanan S; Selman C; Stenvinkel P
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Differences in mitochondrial efficiency explain individual variation in growth performance.

Proceedings. Biological sciences
2019-08 | Journal article
DOI: 10.1098/rspb.2019.1466
PMID: 31431161
PMC: PMC6732382
Contributors: Salin K; Villasevil EM; Anderson GJ; Lamarre SG; Melanson CA; McCarthy I; Selman C; Metcalfe NB
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Progressing the care, husbandry and management of ageing mice used in scientific studies.

Laboratory animals
2019-08 | Journal article
DOI: 10.1177/0023677219865291
PMID: 31403890
PMC: PMC7301645
Contributors: Wilkinson MJ; Selman C; McLaughlin L; Horan L; Hamilton L; Gilbert C; Chadwick C; Flynn JN
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Parasitic worm-derived ES-62 promotes health- and life-span in high calorie diet-fed mice

2019-04 | Preprint
DOI: 10.1101/622753
PPR: PPR77567
Contributors: Crowe J; Lumb FE; Doonan J; Broussard M; Tarafdar A; Pineda MA; Landabaso C; Mulvey L; Hoskisson PA; Babayan SA et al.
Source: Self-asserted source
Colin Selman via Europe PubMed Central

Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity.

Molecular metabolism
2018-11-28 | Journal article
DOI: 10.1016/j.molmet.2018.11.010
PMID: 30553769
PMC: PMC6358539
Source: Self-asserted source
Colin Selman
grade
Preferred source (of 2)‎

Putting a strain on diversity.

The EMBO journal
2018-11-02 | Journal article
DOI: 10.15252/embj.2018100862
PMID: 30389663
Source: Self-asserted source
Colin Selman
grade
Preferred source (of 2)‎

The RCR and ATP/O Indices Can Give Contradictory Messages about Mitochondrial Efficiency.

Integrative and comparative biology
2018-09-01 | Journal article
DOI: 10.1093/icb/icy085
PMID: 29982616
Source: Self-asserted source
Colin Selman

Extracellular Vesicles, Ageing, and Therapeutic Interventions.

Cells
2018-08-18 | Journal article
DOI: 10.3390/cells7080110
PMID: 30126173
PMC: PMC6115766
Source: Self-asserted source
Colin Selman

Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost.

Functional ecology
2018-05-29 | Journal article
DOI: 10.1111/1365-2435.13125
PMID: 30333678
PMC: PMC6175143
Source: Self-asserted source
Colin Selman

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice.

Aging
2018-05-01 | Journal article
DOI: 10.18632/aging.101446
PMID: 29779018
PMC: PMC5990393
Source: Self-asserted source
Colin Selman

Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection.

Scientific reports
2018-02-28 | Journal article
DOI: 10.1038/s41598-018-22083-5
PMID: 29491449
PMC: PMC5830876
Source: Self-asserted source
Colin Selman

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

Cell Metabolism
2017 | Journal article
DOI: 10.1016/j.cmet.2017.05.003
EID:

2-s2.0-85020235166
Contributors: Hine, C.; Kim, H.-J.; Zhu, Y.; Harputlugil, E.; Longchamp, A.; Matos, M.S.; Ramadoss, P.; Bauerle, K.; Brace, L.; Asara, J.M. et al.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Physiology: An atypical switch for metabolism and ageing

Nature
2017 | Journal article
DOI: 10.1038/nature21500
EID:

2-s2.0-85014683443
Contributors: Selman, C.; Withers, D.J.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Proteostasis and ageing: Insights from long-lived mutant mice

Journal of Physiology
2017 | Journal article
DOI: 10.1113/JP274334
EID:

2-s2.0-85026665099
Contributors: Sands, W.A.; Page, M.M.; Selman, C.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier
grade
Preferred source (of 2)‎

Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice

Molecular and Cellular Endocrinology
2016 | Journal article
DOI: 10.1016/j.mce.2016.09.001
EID:

2-s2.0-84992724445
Contributors: Mulvey, L.; Sands, W.A.; Salin, K.; Carr, A.E.; Selman, C.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

Oncotarget
2016 | Journal article
DOI: 10.18632/oncotarget.8729
EID:

2-s2.0-84971505754
Contributors: Selman, C.; Sinclair, A.; Pedroni, S.M.A.; Irvine, E.E.; Michie, A.M.; Withers, D.J.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity

Journal of Experimental Biology
2016 | Journal article
DOI: 10.1242/jeb.133025
EID:

2-s2.0-84983001429
Contributors: Salin, K.; Auer, S.K.; Anderson, G.J.; Selman, C.; Metcalfe, N.B.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Interventions for age-related diseases: Shifting the paradigm

Mechanisms of Ageing and Development
2016 | Journal article
DOI: 10.1016/j.mad.2016.09.009
EID:

2-s2.0-84999035290
Contributors: Figueira, I.; Fernandes, A.; Mladenovic Djordjevic, A.; Lopez-Contreras, A.; Henriques, C.M.; Selman, C.; Ferreiro, E.; Gonos, E.S.; Trejo, J.L.; Misra, J. et al.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Marker-dependent associations among oxidative stress, growth and survival during early life in a wild mammal

Proceedings of the Royal Society B: Biological Sciences
2016 | Journal article
DOI: 10.1098/rspb.2016.1407
EID:

2-s2.0-84991710679
Contributors: Christensen, L.L.; Selman, C.; Blount, J.D.; Pilkington, J.G.; Watt, K.A.; Pemberton, J.M.; Reid, J.M.; Nussey, D.H.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios

Physiological Reports
2016 | Journal article
DOI: 10.14814/phy2.13007
EID:

2-s2.0-84994213326
Contributors: Salin, K.; Villasevil, E.M.; Auer, S.K.; Anderson, G.J.; Selman, C.; Metcalfe, N.B.; Chinopoulos, C.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial leak respiration

Physiological and Biochemical Zoology
2016 | Journal article
DOI: 10.1086/688769
EID:

2-s2.0-84994291705
Contributors: Salin, K.; Auer, S.K.; Rudolf, A.M.; Anderson, G.J.; Selman, C.; Metcalfe, N.B.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Aging in the wild: Insights from free-living and non-model organisms

Experimental Gerontology
2015 | Journal article
DOI: 10.1016/j.exger.2015.09.015
EID:

2-s2.0-84946557713
Contributors: Fletcher, Q.E.; Selman, C.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo

Biology Letters
2015 | Journal article
DOI: 10.1098/rsbl.2015.0538
EID:

2-s2.0-84946195476
Contributors: Salin, K.; Auer, S.K.; Rudolf, A.M.; Anderson, G.J.; Cairns, A.G.; Mullen, W.; Hartley, R.C.; Selman, C.; Metcalfe, N.B.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Longevity and skeletal muscle mass: The role of IGF signalling, the sirtuins, dietary restriction and protein intake

Aging Cell
2015 | Journal article
DOI: 10.1111/acel.12342
EID:

2-s2.0-84958060584
Contributors: Sharples, A.P.; Hughes, D.C.; Deane, C.S.; Saini, A.; Selman, C.; Stewart, C.E.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Oxidative stress and life histories: Unresolved issues and current needs

Ecology and Evolution
2015 | Journal article
DOI: 10.1002/ece3.1790
EID:

2-s2.0-84956818306
Contributors: Speakman, J.R.; Blount, J.D.; Bronikowski, A.M.; Buffenstein, R.; Isaksson, C.; Kirkwood, T.B.L.; Monaghan, P.; Ozanne, S.E.; Beaulieu, M.; Briga, M. et al.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Plasma markers of oxidative stress are uncorrelated in a wild mammal

Ecology and Evolution
2015 | Journal article
DOI: 10.1002/ece3.1771
EID:

2-s2.0-84946478454
Contributors: Christensen, L.L.; Selman, C.; Blount, J.D.; Pilkington, J.G.; Watt, K.A.; Pemberton, J.M.; Reid, J.M.; Nussey, D.H.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance

Proceedings of the Royal Society B: Biological Sciences
2015 | Journal article
DOI: 10.1098/rspb.2015.1028
EID:

2-s2.0-84937918061
Contributors: Salin, K.; Auer, S.K.; Rey, B.; Selman, C.; Metcalfe, N.B.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

Aging Cell
2014 | Journal article
DOI: 10.1111/acel.12241
EID:

2-s2.0-84925235777
Contributors: Jové, M.; Naudí, A.; Ramírez-Núñez, O.; Portero-Otín, M.; Selman, C.; Withers, D.J.; Pamplona, R.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Dietary restriction and the pursuit of effective mimetics

Proceedings of the Nutrition Society
2014 | Journal article
DOI: 10.1017/S0029665113003832
EID:

2-s2.0-84898454337
Contributors: Selman, C.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier

Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice

Obesity
2014 | Journal article
DOI: 10.1002/oby.20418
EID:

2-s2.0-84895802588
Contributors: Zhang, L.-N.; Sinclair, R.; Selman, C.; Mitchell, S.; Morgan, D.; Clapham, J.C.; Speakman, J.R.
Source: Self-asserted source
Colin Selman via Scopus - Elsevier
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