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Works (43)

Chronic intermittent hypoxia modulates corneal fibrotic markers and inflammatory cytokine expression in a sex-dependent manner

Experimental Eye Research
2025-06 | Journal article
DOI: 10.1016/j.exer.2025.110358
Contributors: Jessica L. Bradshaw; Brenda Vasini; Steve Mabry; Brenna S. Hefley; E. Nicole Wilson; Jennifer J. Gardner; Rebecca L. Cunningham; Dimitrios Karamichos
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Fabrication of a 3D Corneal Model Using Collagen Bioink and Human Corneal Stromal Cells

Journal of Functional Biomaterials
2025-03-28 | Journal article
DOI: 10.3390/jfb16040118
Contributors: Alexander J. Choi; Brenna S. Hefley; Hannah A. Strobel; Sarah M. Moss; James B. Hoying; Sarah E. Nicholas; Shadi Moshayedi; Jayoung Kim; Dimitrios Karamichos
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Corneal epithelial-stromal constructs to study differences associated with diabetes mellitus

Experimental Eye Research
2024-11 | Journal article
DOI: 10.1016/j.exer.2024.110100
Contributors: Brenna S. Hefley; Tina B. McKay; Audrey E.K. Hutcheon; Joseph B. Ciolino; Dimitrios Karamichos
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Decreased Circulating Gonadotropin-Releasing Hormone Associated with Keratoconus

Cells
2024-10-15 | Journal article
DOI: 10.3390/cells13201704
Contributors: Paulina Escandon; Alexander J. Choi; Steve Mabry; Sarah E. Nicholas; Rebecca L. Cunningham; Liam Redden; David A. Murphy; Kamran M. Riaz; Tina B. McKay; Dimitrios Karamichos
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Amelioration of Fibrosis via S1P Inhibition Is Regulated by Inactivation of TGF-β and SPL Pathways in the Human Cornea

International Journal of Molecular Sciences
2024-06-14 | Journal article
DOI: 10.3390/ijms25126560
Contributors: Sarah E. Nicholas; Sandip K. Basu; Nawajes Mandal; Dimitrios Karamichos
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Effects of hypoxia in the diabetic corneal stroma microenvironment

Experimental Eye Research
2024-03 | Journal article
DOI: 10.1016/j.exer.2024.109790
Contributors: Purnima Sharma; Jian-Xing Ma; Dimitrios Karamichos
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Prospective Observational Study Evaluating Systemic Hormones and Corneal Crosslinking Effects in Keratoconus

Ophthalmology Science
2024-03 | Journal article
DOI: 10.1016/j.xops.2023.100364
Contributors: Lyly Van; Sashia Bennett; Sarah E. Nicholas; Jesper Hjortdal; Tina B. McKay; Dimitrios Karamichos
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Cell sheet-based approach to study the diabetic corneal stroma

Experimental Eye Research
2023-12 | Journal article
DOI: 10.1016/j.exer.2023.109717
Contributors: Shrestha Priyadarsini; Tina B. McKay; Paulina Escandon; Sarah E. Nicholas; Jian-Xing Ma; Dimitrios Karamichos
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Exosomes and their miRNA/protein profile in keratoconus-derived corneal stromal cells

Experimental Eye Research
2023-11 | Journal article
DOI: 10.1016/j.exer.2023.109642
Contributors: Rachel Hadvina; Mariam Lotfy Khaled; Theresa Akoto; Wenbo Zhi; Dimitrios Karamichos; Yutao Liu
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Selective Modulation of the Keratoconic Stromal Microenvironment by FSH and LH

The American Journal of Pathology
2023-11 | Journal article
DOI: 10.1016/j.ajpath.2023.02.002
Contributors: Paulina Escandon; Sarah E. Nicholas; Brenda Vasini; Rebecca L. Cunningham; David A. Murphy; Kamran M. Riaz; Dimitrios Karamichos
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Quercetin and Related Analogs as Therapeutics to Promote Tissue Repair

Bioengineering
2023-09-25 | Journal article
DOI: 10.3390/bioengineering10101127
Contributors: Tina B. McKay; Kyle A. Emmitte; Carrie German; Dimitrios Karamichos
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Potentiation of Sphingolipids and TGF-β in the human corneal stroma reveals intricate signaling pathway crosstalks

Experimental Eye Research
2023-06 | Journal article
DOI: 10.1016/j.exer.2023.109487
Contributors: Sarah E. Nicholas; Alexander J. Choi; Thi N. Lam; Sandip K. Basu; Nawajes Mandal; Dimitrios Karamichos
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Collagen Crosslinking for Keratoconus: Cellular Signaling Mechanisms

Biomolecules
2023-04-20 | Journal article
DOI: 10.3390/biom13040696
Contributors: Dimitrios Karamichos; Sarah E. Nicholas; Asher Khan; Kamran M. Riaz
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Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus—A Transcriptomic Profiling Study

International Journal of Molecular Sciences
2023-04-18 | Journal article
DOI: 10.3390/ijms24087437
Contributors: Theresa Akoto; Jingwen Cai; Sarah Nicholas; Hayden McCord; Amy J. Estes; Hongyan Xu; Dimitrios Karamichos; Yutao Liu
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Peroxisome proliferator-activated receptor-α (PPARα) regulates wound healing and mitochondrial metabolism in the cornea

Proceedings of the National Academy of Sciences
2023-03-28 | Journal article
DOI: 10.1073/pnas.2217576120
Contributors: Wentao Liang; Li Huang; Amy Whelchel; Tian Yuan; Xiang Ma; Rui Cheng; Yusuke Takahashi; Dimitrios Karamichos; Jian-Xing Ma
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Salivary Exosomes in Health and Disease: Future Prospects in the Eye

International Journal of Molecular Sciences
2023-03-28 | Journal article
DOI: 10.3390/ijms24076363
Contributors: Angela Liu; Brenna Hefley; Paulina Escandon; Sarah E. Nicholas; Dimitrios Karamichos
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Prolactin-Induced Protein facilitates corneal wound healing

Experimental Eye Research
2022-12 | Journal article
DOI: 10.1016/j.exer.2022.109300
Contributors: Wentao Liang; Jian-Xing Ma; Lyly Van; Brenda Vasini; Dimitrios Karamichos
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Revealing the presence of tear extracellular vesicles in Keratoconus

Experimental Eye Research
2022-11 | Journal article
DOI: 10.1016/j.exer.2022.109242
Contributors: Brenna S. Hefley; Clayton Deighan; Brenda Vasini; Asher Khan; Jesper Hjortdal; Kamran M. Riaz; Yutao Liu; Dimitrios Karamichos
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Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes

Analytical Cellular Pathology
2022-10-26 | Journal article
DOI: 10.1155/2022/6718566
Contributors: Pawan Shrestha; Amy E. Whelchel; Sarah E. Nicholas; Wentao Liang; Jian-Xing Ma; Dimitrios Karamichos; Mahmood Rasool
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Quercetin Decreases Corneal Haze In Vivo and Influences Gene Expression of TGF-Beta Mediators In Vitro

Metabolites
2022-07-07 | Journal article
DOI: 10.3390/metabo12070626
Contributors: Tina B. McKay; Pouriska B. Kivanany; Sarah E. Nicholas; Okhil K. Nag; Michael H. Elliott; W. Matthew Petroll; Dimitrios Karamichos
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Anterior pituitary, sex hormones, and keratoconus: Beyond traditional targets

Progress in Retinal and Eye Research
2022-05 | Journal article
DOI: 10.1016/j.preteyeres.2021.101016
Contributors: Dimitrios Karamichos; Paulina Escandon; Brenda Vasini; Sarah E. Nicholas; Lyly Van; Deanna H. Dang; Rebecca L. Cunningham; Kamran M. Riaz
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Unravelling Novel Roles of Salivary Exosomes in the Regulation of Human Corneal Stromal Cell Migration and Wound Healing

International Journal of Molecular Sciences
2022-04 | Journal article | Author
DOI: 10.3390/ijms23084330
Contributors: Paulina Escandon; Angela Liu; Sarah E. Nicholas; Asher Khan; Kamran M. Riaz; dimitrios karamichos
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Multidisciplinary Digital Publishing Institute
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Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets

Drugs
2022-02 | Journal article
DOI: 10.1007/s40265-021-01660-5
Contributors: Deanna H. Dang; Kamran M. Riaz; Dimitrios Karamichos
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The Role of Estriol and Estrone in Keratoconic Stromal Sex Hormone Receptors

International Journal of Molecular Sciences
2022-01-14 | Journal article
DOI: 10.3390/ijms23020916
Contributors: Paulina Escandon; Sarah E. Nicholas; Rebecca L. Cunningham; David A. Murphy; Kamran M. Riaz; Dimitrios Karamichos
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Sex Hormones, Growth Hormone, and the Cornea

Cells
2022-01-11 | Journal article
DOI: 10.3390/cells11020224
Contributors: Tina B. McKay; Shrestha Priyadarsini; Dimitrios Karamichos
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FAK Inhibition Attenuates Corneal Fibroblast Differentiation In Vitro

Biomolecules
2021-11-12 | Journal article
DOI: 10.3390/biom11111682
Contributors: Vincent Yeung; Sriniwas Sriram; Jennifer A. Tran; Xiaoqing Guo; Audrey E. K. Hutcheon; James D. Zieske; Dimitrios Karamichos; Joseph B. Ciolino
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The role of peroxisome proliferator-activated receptors in healthy and diseased eyes

Experimental Eye Research
2021-07 | Journal article
DOI: 10.1016/j.exer.2021.108617
Contributors: Paulina Escandon; Brenda Vasini; Amy E. Whelchel; Sarah E. Nicholas; H. Greg Matlock; Jian-Xing Ma; Dimitrios Karamichos
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A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment

Experimental Eye Research
2021-06 | Journal article
DOI: 10.1016/j.exer.2021.108581
Contributors: Marina E. Brown; Micaela L. Montgomery; Manali M. Kamath; Sarah Nicholas; Yutao Liu; Dimitrios Karamichos; Kevin K. Fuller
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Cellular Contractility Profiles of Human Diabetic Corneal Stromal Cells

Analytical Cellular Pathology
2021-06-04 | Journal article
DOI: 10.1155/2021/9913210
Contributors: Thi N. Lam; Sarah E. Nicholas; Alexander Choi; Jian-Xing Ma; Dimitrios Karamichos; Viswanathan Pragasam
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A New Era for Analytical Cellular Pathology

Analytical Cellular Pathology
2020-01-14 | Journal article
DOI: 10.1155/2020/8502160
Contributors: Dimitrios Karamichos
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Corneal Epithelial–Stromal Fibroblast Constructs to Study Cell–Cell Communication in Vitro

Bioengineering
2019-12-04 | Journal article
DOI: 10.3390/bioengineering6040110
Contributors: Tina B. McKay; Dimitrios Karamichos; Audrey E. K. Hutcheon; Xiaoqing Guo; James D. Zieske
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Gonadotropins in Keratoconus: The Unexpected Suspects

Cells
2019-11-22 | Journal article
DOI: 10.3390/cells8121494
Contributors: Dimitrios Karamichos; Brayden Barrientez; Sarah Nicholas; Symon Ma; Lyly Van; Sashia Bak-Nielsen; Jesper Hjortdal
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Mechanisms of Collagen Crosslinking in Diabetes and Keratoconus

Cells
2019-10-11 | Journal article
DOI: 10.3390/cells8101239
Contributors: Tina B. McKay; Shrestha Priyadarsini; Dimitrios Karamichos
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Collagen cross-linking impact on keratoconus extracellular matrix

PLOS ONE
2018-07-18 | Journal article
DOI: 10.1371/journal.pone.0200704
Contributors: Rabab Sharif; Rajiv R. Mohan; Ben Fowler; Dimitrios Karamichos
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The role of lipids in corneal diseases and dystrophies: a systematic review

Clinical and Translational Medicine
2017-12 | Journal article
DOI: 10.1186/s40169-017-0158-1
Contributors: Tyler G. Rowsey; Dimitrios Karamichos
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Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma

PLOS ONE
2017-08-14 | Journal article
DOI: 10.1371/journal.pone.0182390
Contributors: Sarah E. Nicholas; Ashley Cowart; Tyler G. Rowsey; Shrestha Priyadarsini; Nawajes A. Mandal; Dimitrios Karamichos
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Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro

PLOS ONE
2017-04-20 | Journal article
DOI: 10.1371/journal.pone.0176017
Contributors: Tina B. McKay; Alexander V. Ljubimov; Jesper Hjortdal; Shrestha Priyadarsini; Dimitrios Karamichos
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A Systematic Review of the Role of Dysfunctional Wound Healing in the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis

Journal of Clinical Medicine
2016-12 | Journal article
DOI: 10.3390/jcm6010002
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Multidisciplinary Digital Publishing Institute
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Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma

Experimental Eye Research
2016-12 | Journal article
DOI: 10.1016/j.exer.2016.10.010
Contributors: Shrestha Priyadarsini; Tina B. McKay; Akhee Sarker-Nag; Jeremy Allegood; Charles Chalfant; Jian-Xing Ma; Dimitrios Karamichos
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Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes

PLOS ONE
2016-12-22 | Journal article
DOI: 10.1371/journal.pone.0168845
Contributors: Shrestha Priyadarsini; Alexander V. Ljubimov; Akhee Sarker-Nag; Tyler G. Rowsey; Jian-Xing Ma; Dimitrios Karamichos
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Human Keratoconus Cell Contractility is Mediated by Transforming Growth Factor-Beta Isoforms

Journal of Functional Biomaterials
2015-06-18 | Journal article
DOI: 10.3390/jfb6020422
Contributors: Desiree' Lyon; Tina McKay; Akhee Sarkar-Nag; Shrestha Priyadarsini; Dimitrios Karamichos
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Ocular Tissue Engineering: Current and Future Directions

Journal of Functional Biomaterials
2015-02-17 | Journal article
DOI: 10.3390/jfb6010077
Contributors: D. Karamichos
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Keratoconus: Tissue Engineering and Biomaterials

Journal of Functional Biomaterials
2014-09-11 | Journal article
DOI: 10.3390/jfb5030111
Contributors: Dimitrios Karamichos; Jesper Hjortdal
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Peer review (1 review for 1 publication/grant)

Review activity for Nature reviews. (1)
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