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Works (7)

Bacterial expression, purification, and characterization of human cytochrome P450 3A4 without N-terminal modifications

Archives of Biochemistry and Biophysics
2024-12 | Journal article
DOI: 10.1016/j.abb.2024.110208
Contributors: Yudong Sun; Yoichi Osawa; Haoming Zhang
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A General Method to Screen Nanobodies for Cytochrome P450 Enzymes from a Yeast Surface Display Library

Biomedicines
2024-08-15 | Journal article
DOI: 10.3390/biomedicines12081863
Contributors: Yudong Sun; Cristian Martinez-Ramos; Eugene Chen; Yoichi Osawa; Haoming Zhang
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The Versatile Biocatalyst of Cytochrome P450 CYP102A1: Structure, Function, and Engineering

Molecules
2023-07-12 | Journal article
DOI: 10.3390/molecules28145353
Contributors: Yudong Sun; Xiaoqiang Huang; Yoichi Osawa; Yuqing Eugene Chen; Haoming Zhang
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Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 CYP2B4 and NADPH-cytochrome P450 oxidoreductase

Journal of Biological Chemistry
2021-01 | Journal article
DOI: 10.1016/j.jbc.2021.100645
Contributors: Shen Cheng; Zhiyuan Bo; Paul Hollenberg; Yoichi Osawa; Haoming Zhang
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Cryo-EM reveals the architecture of the dimeric cytochrome P450 CYP102A1 enzyme and conformational changes required for redox partner recognition

Journal of Biological Chemistry
2020-02 | Journal article
DOI: 10.1074/jbc.RA119.011305
Contributors: Min Su; Sumita Chakraborty; Yoichi Osawa; Haoming Zhang
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Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells

Cellular and Molecular Gastroenterology and Hepatology
2019-06 | Journal article
DOI: 10.1016/j.jcmgh.2019.05.010
Contributors: Dhiman Maitra; Eric L. Carter; Rani Richardson; Laure Rittié; Venkatesha Basrur; Haoming Zhang; Alexey I. Nesvizhskii; Yoichi Osawa; Matthew W. Wolf; Stephen W. Ragsdale et al.
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The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis

Journal of Biological Chemistry
2018-05 | Journal article
DOI: 10.1074/jbc.RA117.000600
Contributors: Haoming Zhang; Adam L. Yokom; Shen Cheng; Min Su; Paul F. Hollenberg; Daniel R. Southworth; Yoichi Osawa
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Peer review (10 reviews for 7 publications/grants)

Review activity for Acta pharmaceutica sinica B. (2)
Review activity for Biochemistry. (1)
Review activity for Biophysical chemistry. (2)
Review activity for Cardiovascular drugs and therapy. (2)
Review activity for Chemical research in toxicology. (1)
Review activity for The journal of physical chemistry. (1)
Review activity for The Journal of steroid biochemistry and molecular biology. (1)
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