Personal information

Activities

Employment (1)

Alex-Ekwueme Federal University Ndufu Alike Ikwo: Abakaliki, Ebonyi State, NG

2012-09-02 to present | Lecturer/Researcher (Medical Biochemistry)
Employment
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Ademola C Famurewa

Education and qualifications (1)

Alex-Ekwueme Federal University Ndufu Alike, Ikwo : Abakaliki, Ebonyi State, NG

2012-09-02 to present | PhD (Medical Biochemistry)
Education
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Ademola C Famurewa

Works (50 of 60)

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Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats

Drug and Chemical Toxicology
2024-09-02 | Journal article
Contributors: Azza Sedky; Ademola C. Famurewa
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The Therapeutic Mechanisms of Honey in Mitigating Toxicity from Anticancer Chemotherapy Toxicity: A Review

Journal of Xenobiotics
2024-08-20 | Journal article
Contributors: Debalina Bose; Ademola C. Famurewa; Aman Akash; Eman M. Othman
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Natural Bioactive Compounds and Human Health

Molecules
2024-07-18 | Journal article
Contributors: Arunaksharan Narayanankutty; Ademola C. Famurewa; Eliza Oprea
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Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats

Drug and Chemical Toxicology
2024-07-03 | Journal article
Contributors: Manal A. Alfwuaires; Ademola C. Famurewa; Abdulmohsen I. Algefare; Azza Sedky
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Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling pathways in rats

Toxicology Research
2024-05-01 | Journal article
Contributors: Irmak Ferah Okkay; Ademola Famurewa; Cemil Bayram; Ufuk Okkay; Ali Sefa Mendil; Selma Sezen; Teslime Ayaz; Ibrahim Gecili; Mustafa Ozkaraca; Selcuk Senyayla et al.
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Epigenetic Alterations in Alzheimer’s Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems

Biology
2024-02-28 | Journal article
Contributors: Alosh Greeny; Ayushi Nair; Prashant Sadanandan; Sairaj Satarker; Ademola C. Famurewa; Madhavan Nampoothiri
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Antidiabetic drug sitagliptin blocks cyclophosphamide cerebral neurotoxicity by activating Nrf2 and suppressing redox cycle imbalance, inflammatory iNOS/NO/NF-Kappa B response and caspase-3/Bax activation in rats

International Immunopharmacology
2023 | Journal article
Contributors: Famurewa, Ademola C.; Asogwa, Nnaemeka T.; Ezea, Samson C.
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Cytotoxic Activity of Herbal Medicines as Assessed <i>in Vitro</i>: A Review

Chemistry and Biodiversity
2023 | Journal article
Contributors: Gavanji, Shahin; Bakhtari, Azizollah; Famurewa, Ademola C.; Othman, Eman M.
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Naringin ameliorates 5-fluorouracil induced cardiotoxicity: An insight into its modulatory impact on oxidative stress, inflammatory and apoptotic parameters

Tissue and Cell
2023 | Journal article
Contributors: Gui, Yang; Famurewa, Ademola C.; Olatunji, Opeyemi Joshua
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Lipoic acid abates testis lead accumulation, sperm-endocrine deficits, testicular oxidative inflammation and apoptosis and modulates gene expression of Bax and Bcl-2 in rats

Scientific African
2023-09 | Journal article
Contributors: Ademola C. Famurewa; Hamida Hamdi; Azza Sedky
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Role of Chitosan-Loaded Solanine Glycoalkaloid from <i>Solanum scabrum</i> Mill. Leaf Extract as Anti-Inflammatory and <i>In Vitro</i> Anticancer Agents

Turkish Journal of Pharmaceutical Sciences
2023-08-22 | Journal article
Contributors: Cletus Anes UKWUBILE; Emmanuel Oise IKPEFAN; Ademola Clement FAMUREWA
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Comparative assessment of different coconut oils: Chromatographic and spectrometric analyses of pesticide residues, toxic heavy metals, and associated contents

Measurement: Food
2023-06 | Journal article
Contributors: Ademola C. Famurewa; Chima A. Ekeleme-Egedigwe; Chimaraoke Onyeabo; Shadrach C. Kanu; Elizabeth E. Besong; Ekenechukwu K. Maduagwuna
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Comparative studies on the amino acids, pesticide residue content, biogenic and toxic elements in an underutilized nut: Bambara groundnut (Vigna subterranea)

Journal of Trace Elements and Minerals
2023-03 | Journal article
Contributors: Chima A. Egedigwe-Ekeleme; Ademola C. Famurewa; Uchenna O. Egedigwe; Chimaraoke Onyeabo; Shedrach C. Kanu; Shedrack C. Ogunwa; Chinwendu A. Onuora; Anthonia O. Agbo
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Resveratrol Mitigates Diabetic Testicular Dysfunction, Endocrine Deficits, and Insulin Resistance via Suppression of Sperm-Endocrine Aberrations and Oxidative Inflammation in Rats

Andrologia
2023-02-06 | Journal article
Contributors: Hany Elsawy; Ademola C. Famurewa; Azza Sedky; Vikas Kumar Roy
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<i>Cucumeropsis mannii</i> seed oil (CMSO) attenuates alterations in testicular biochemistry and histology against Bisphenol a-induced toxicity in male Wister albino rats

Heliyon
2022 | Journal article
Contributors: Agu, P. C.; Aja, P. M.; Ugbala, Ezebuilo Ekpono; Ogwoni, H. A.; Ezeh, E. M.; Oscar-Amobi, P. C.; Atamgba, Agbor Asuk; Ani, O. G.; Awoke, J. N.; Nwite, F. E. et al.
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Antimicrobial and Larvicidal Activities of Different Ocimum Essential Oils Extracted by Ultrasound-Assisted Hydrodistillation

Molecules
2022 | Journal article
Contributors: Sneha, Kuzhimbattil; Narayanankutty, Arunaksharan; Job, Joice Tom; Olatunji, Opeyemi Joshua; Alfarhan, Ahmed; Famurewa, Ademola C.; Ramesh, Varsha
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Buchholzia coriacea seed extract attenuates mercury-induced cerebral and cerebellar oxidative neurotoxicity via NO signaling and suppression of oxidative stress, adenosine deaminase and acetylcholinesterase activities in rats

Avicenna Journal of Phytomedicine
2022 | Journal article
Contributors: Egba, Simeon, I; Famurewa, Ademola C.; Omoruyi, Lilian E.
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Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

Biomedicine & Pharmacotherapy
2022 | Journal article
Contributors: Famurewa, Ademola C.; Renu, Kaviyarasi; Eladl, Mohamed Ahmed; Chakraborty, Rituraj; Myakala, Haritha; El-Sherbiny, Mohamed; Elsherbini, Dalia Mahmoud Abdelmonem; Vellingiri, Balachandar; Madhyastha, Harishkumar; Wanjari, Uddesh Ramesh et al.
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Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-alpha/NF-kappa B/caspase-3 signaling in type 2 diabetes rats

Nutritional Neuroscience
2022 | Journal article
Contributors: Chen, Xiao; Famurewa, Ademola C.; Tang, Jian; Olatunde, Oladipupo Odunayo; Olatunji, Opeyemi Joshua
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Repurposing FDA-approved drugs against the toxicity of platinum-based anticancer drugs

Life Sciences
2022 | Journal article
Contributors: Famurewa, Ademola C.; Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Sukumar, Aarthi; Murali, Reshma; Renu, Kaviyarasi; Vellingiri, Balachandar; Dey, Abhijit; Gopalakrishnan, Abilash Valsala
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Tiliacora triandra attenuates cisplatin triggered hepatorenal and testicular toxicity in rats by modulating oxidative inflammation, apoptosis and endocrine deficit

Frontiers in Bioscience-Landmark
2022 | Journal article
Contributors: Zhang, Xiaomin; Peng, Xiaozhuang; Wang, Chen; Olatunji, Opeyemi Joshua; Famurewa, Ademola
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Variations in the composition, cytoprotective and anti-inflammatory effects of natural polyphenols of edible oils extracted from fresh and dried coconut testa

Physiological and Molecular Plant Pathology
2022 | Journal article
Contributors: Narayanankutty, Arunaksharan; Kunnath, Krishnaprasad; Famurewa, Ademola C.; Ramesh, Varsha; Rajagopal, Rajakrishnan; Alfarhan, Ahmed
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Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia

Antibiotics
2022-11-03 | Journal article
Contributors: Jawaher J. Albaqami; Hamida Hamdi; Arunaksharan Narayanankutty; Naduvilthara U. Visakh; Anju Sasidharan; Aswathi Moothakoottil Kuttithodi; Ademola C. Famurewa; Berin Pathrose
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Silymarin abrogates acrylamide‐induced oxidative stress‐mediated testicular toxicity via modulation of antioxidant mechanism, DNA damage, endocrine deficit and sperm quality in rats

Andrologia
2022-10 | Journal article
Contributors: Hissah Ahmed Alturki; Hany Amin Elsawy; Ademola Clement Famurewa
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Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Exhibits Antioxidant Mechanism for Abrogation of Cyclophosphamide-Induced Cardiac Damage and Oxidative Hepatorenal Toxicity in Rats

Drug Research
2022-09 | Journal article
Contributors: Ademola C. Famurewa; Patrick M. Aja; John O. Medewase; Innocent Abi; Okoro C. Ogbonna; Casimir C. Ofor; Charles O. Nwonuma; Nnaemeka T Asogwa; Omotayo O. Erejuwa
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<i>Tiliacora triandra</i>extract and its major constituent attenuates diabetic kidney and testicular impairment by modulating redox imbalance and pro-inflammatory responses in rats

Journal of the Science of Food and Agriculture
2021 | Journal article
Contributors: Song, Peng; Sun, Chen; Li, Jinbo; Long, Tong; Yan, Yixin; Qin, Hongping; Makinde, Emmanuel Ayobami; Famurewa, Ademola C.; Jaisi, Amit; Nie, Ying et al.
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Antidiabetic and Nephroprotective Effects of Polysaccharide Extract from the Seaweed Caulerpa racemosa in High Fructose-Streptozotocin Induced Diabetic Nephropathy

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
2021 | Journal article
Contributors: Cao, Meng; Li, Yan; Famurewa, Ademola C.; Olatunji, Opeyemi Joshua
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Antioxidant and Anti-inflammatory Properties Mediate the Neuroprotective Effects of Hydro-ethanolic Extract of Tiliacora triandra Against Cisplatin-induced Neurotoxicity

Journal of Inflammation Research
2021 | Journal article
Contributors: Huang, Yanping; Liu, Chunhong; Song, Xianbing; An, Mei; Liu, Meimei; Yao, Lei; Famurewa, Ademola C.; Olatunji, Opeyemi Joshua
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Antioxidant, anti-inflammatory, analgesic and in vitro-in vivo cytotoxicity effects of Spondias Venulosa (Engl.) Engl. leaf extracts on MCF-7/S0.5 and OV7 cancer cell lines

Scientific African
2021 | Journal article
Contributors: Ukwubile, Cletus A.; Ikpefan, Emmanuel O.; Malgwi, Troy S.; Dibal, Musa Y.; Famurewa, Ademola C.; Rasheed-Jada, Hadiza; Milagawanda, Hananiya H.; Suleiman, Abubakar U.
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Downregulation of redox imbalance and iNOS/NF-kappa B/caspase-3 signalling with zinc supplementation prevents urotoxicity of cyclophosphamide-induced hemorrhagic cystitis in rats

Life Sciences
2021 | Journal article
Contributors: Famurewa, Ademola C.; Edeogu, C. O.; Offor, Florence, I; Besong, Elizabeth E.; Akunna, Gabriel G.; Maduagwuna, Ekenechukwu K.
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Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium) - induced hepatotoxicity - A review

Chemosphere
2021 | Journal article
Contributors: Renu, Kaviyarasi; Chakraborty, Rituraj; Myakala, Haritha; Koti, Rajeshwari; Famurewa, Ademola C.; Madhyastha, Harishkumar; Vellingiri, Balachandar; George, Alex; Gopalakrishnan, Abilash Valsala
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Protective effects of Dialium guineense pulp on aspirin- induced gastric mucosal injury in albino rats

Journal of Applied Biomedicine
2021 | Journal article
Contributors: Obasi, Nwogo Ajuka; Aloke, Chinyere; Obasi, Stella Eberechukwu; Egwu, Chinedu Ogbonnia; Famurewa, Ademola Clement; Ogbu, Patience Nkemjika
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Hepatoprotective effect of polyphenols isolated from virgin coconut oil against sub-chronic cadmium hepatotoxicity in rats is associated with improvement in antioxidant defense system

Drug and Chemical Toxicology
2021-07-04 | Journal article
Contributors: Ademola C. Famurewa; Chioma S. Ugwu-Ejezie; Eghosa E. Iyare; Abiola M. Folawiyo; Ekenechukwu K. Maduagwuna; Fidelis E. Ejezie
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Virgin Coconut Oil Resists Arsenic-Induced Cerebral Neurotoxicity and Cholesterol Imbalance via Suppression of Oxidative Stress, Adenosine Deaminase and Acetylcholinesterase Activities in Rats

Natural Product Communications
2021-06 | Journal article
Contributors: Sharon O. Azubuike-Osu; Ademola C. Famurewa; Japheth C. David; Innocent Abi; Patience N. Ogbu; Chiedozie K. Oparaji; Konyefom G. Nwaeze; Godson G. Akunna
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Aqueous peel extract of Citrus aurantifolia attenuated tramadol-mediated testicular oxidative stress, apoptosis, inflammations and histo-architectural degeneration in a rat model

European Journal of Anatomy
2020 | Journal article
Contributors: Akunna, Gabriel; Ihechu, Philip; Ajeleti, Akinola; Olabiyi, Olaleye; Famurewa, Ademola; Enye, Linus; Morakinyo, Amos
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Effect of parboiling on toxic metal content and nutritional composition of three rice varieties locally produced in Nigeria

Scientific African
2020 | Journal article
Contributors: David, Ebuka E.; Nwobodo, Valentine; Famurewa, Ademola C.; Igwenyi, Ikechukwu O.; Egedeigwe-Ekeleme, Chima A.; Obeten, Uket N.; Obasi, Doris O.; Ezeilo, Uchenna R.; Emeribole, Monday N.
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Elemental Composition and Associated Health Risk of Honey Obtained from Apiary Farms in Southeast Nigeria

Journal of Food Protection
2020 | Journal article
Contributors: Obasi, Nwogo Ajuka; Aloke, Chinyere; Obasi, Stella Eberechukwu; Famurewa, Ademola Clement; Ogbu, Patience Nkemjika; Onyeji, Gertrude Nneka
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Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-kappa B signaling in rats

Life Sciences
2020 | Journal article
Contributors: Aja, Patrick M.; Izekwe, Friday I.; Famurewa, Ademola C.; Ekpono, Ezebuilo U.; Nwite, Felix E.; Igwenyi, Ikechuku O.; Awoke, Joshua N.; Ani, Onyedika G.; Aloke, Chinyere; Obasi, Nwogo A. et al.
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Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats

Avicenna Journal of Phytomedicine
2020 | Journal article
Contributors: Famurewa, Ademola C.; Akunna, Gabriel G.; Nwafor, Joseph; Chukwu, Onyebuchi C.; Ekeleme-Egedigwe, Chima A.; Oluniran, Janet N.
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Protective Effects of Nucleosides-Rich Extract from <i>Cordyceps cicadae</i> against Cisplatin Induced Testicular Damage

Chemistry and Biodiversity
2020 | Journal article
Contributors: Wang, Ling; He, Yigang; Li, Yudi; Pei, Chengbin; Olatunji, Opeyemi Joshua; Tang, Jian; Famurewa, Ademola C.; Wang, Hongyan; Yan, Bei
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Y Hesperidin ameliorates hepatic dysfunction and dyslipidemia in male Wistar rats exposed to cadmium chloride

Toxicology Reports
2020 | Journal article
Contributors: Aja, P. M.; Ekpono, E. U.; Awoke, J. N.; Famurewa, A. C.; Izekwe, F. I.; Okoro, E. J.; Okorie, C. F.; Orji, C. L.; Nwite, F.; Ale, B. A. et al.
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Ginger juice prevents cisplatin‐induced oxidative stress, endocrine imbalance and NO/iNOS/NF‐κB signalling via modulating testicular redox‐inflammatory mechanism in rats

Andrologia
2020-11-10 | Journal article
Contributors: Ademola C. Famurewa; Chima A. Ekeleme‐Egedigwe; Chikodili S. Onwe; Uchenna O. Egedigwe; Chukwuemeka O. Okoro; Ugochukwu J. Egedigwe; Nnaemeka T. Asogwa
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Nephroprotective Effect of Moringa Oleifera Seed Oil on Gentamicin-Induced Nephrotoxicity in Rats: Biochemical Evaluation of Antioxidant, Anti-inflammatory, and Antiapoptotic Pathways

Journal of the American College of Nutrition
2020-05-18 | Journal article
Contributors: C. O. Edeogu; Michael E. Kalu; Ademola C. Famurewa; Nnaemeka T. Asogwa; Gertrude N. Onyeji; Kelechi O. Ikpemo
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Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signaling, and caspase-3-dependent apoptosis in female rats

Toxicology Mechanisms and Methods
2020-02-12 | Journal article
Contributors: Ademola C. Famurewa; Chima A. Ekeleme-Egedigwe; Ebuka E. David; Chinedum O. Eleazu; Abiola M. Folawiyo; Nwogo A. Obasi
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Antioxidant, anti‐inflammatory, and antiapoptotic effects of virgin coconut oil against antibiotic drug gentamicin‐induced nephrotoxicity via the suppression of oxidative stress and modulation of iNOS/NF‐ĸB/caspase‐3 signaling pathway in Wistar rats

Journal of Food Biochemistry
2020-01-12 | Journal article
Contributors: Ademola C. Famurewa; Ekenechukwu K. Maduagwuna; Abiola M. Folawiyo; Elizabeth E. Besong; Albert N. Eteudo; Opeyemi A. Famurewa; Fidelis E. Ejezie
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<i>Moringa oleifera</i> seed oil modulates redox imbalance and iNOS/NF-κB/caspase-3 signaling pathway to exert antioxidant, anti-inflammatory and antiapoptotic mechanisms against anticancer drug 5-fluorouracil-induced nephrotoxicity in rats

South African Journal of Botany
2019 | Journal article
Contributors: Famurewa, A. C.; Asogwa, N. T.; Aja, P. M.; Akunna, G. G.; Awoke, J. N.; Ekeleme-Egedigwe, C. A.; Maduagwuna, E. K.; Folawiyo, A. M.; Besong, E. E.; Ekpono, E. U. et al.
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Abrogation of Hepatic Damage Induced by Anticancer Drug Methotrexate by Zobo (Hibiscus sabdariffa extract) Supplementation via Targeting Oxidative Hepatotoxicity in Rats

Journal of Dietary Supplements
2019 | Journal article
Contributors: Famurewa, Ademola C.; Folawiyo, Abiola M.; Epete, Michael A.; Igwe, Emeka C.; Okike, Paul, I; Maduagwuna, Ekenechukwu K.
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Modulation of the Lipid Profile, Hepatic and Renal Antioxidant Activities, and Markers of Hepatic and Renal Dysfunctions in Alloxan-Induced Diabetic Rats by Virgin Coconut Oil

Endocrine, Metabolic & Immune Disorders-Drug Targets
2019 | Journal article
Contributors: Eleazu, Chinedum; Ekeleme, Chima E.; Famurewa, Ademola; Mohamed, Mahaneem; Akunna, Gabriel; David, Ebuka; Nwofe, Boniface; Chukwu, Favour; Precious, Amakor; Ayogu, Charles et al.
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Antioxidant potential of garlic oil supplementation prevents cyclophosphamide-induced oxidative testicular damage and endocrine depletion in rats

Journal of Nutrition & Intermediary Metabolism
2019-12 | Journal article
Contributors: Chima A. Ekeleme-Egedigwe; Ademola C. Famurewa; Ebuka E. David; Chinedum O. Eleazu; Uchenna O. Egedigwe
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Antioxidant and anti-inflammatory mechanisms of polyphenols isolated from virgin coconut oil attenuate cadmium-induced oxidative stress-mediated nephrotoxicity and inflammation in rats

Journal of Applied Biomedicine
2018 | Journal article
Contributors: Famurewa, Ademola C.; Ejezie, Abumchukwu J.; Ugwu-Ejezie, Chioma S.; Ikekpeazu, Ebele J.; Ejezie, Fidelis E.
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Peer review (177 reviews for 47 publications/grants)

Review activity for Andrologia. (2)
Review activity for Applied physiology, nutrition, and metabolism. (3)
Review activity for Aspects of molecular medicine. (1)
Review activity for Biomedicine & pharmacotherapy. (3)
Review activity for Biotechnic & histochemistry. (1)
Review activity for BMC complementary medicine and therapies. (3)
Review activity for Brazilian Archives of Biology and Technology. (2)
Review activity for British journal of nutrition. (1)
Review activity for Cancer investigation. (1)
Review activity for Chemistry & biodiversity. (2)
Review activity for Clinical and experimental pharmacology & physiology. (1)
Review activity for Cogent food & agriculture. (1)
Review activity for Drug and chemical toxicology. (63)
Review activity for Drug delivery. (1)
Review activity for Drug research. (2)
Review activity for Environmental science and pollution research international (1)
Review activity for Environmental science and pollution research international (1)
Review activity for Environmental toxicology. (2)
Review activity for European journal of pharmacology. (1)
Review activity for Expert review of clinical pharmacology (1)
Review activity for Food and chemical toxicology. (2)
Review activity for Food science & nutrition. (1)
Review activity for Human & experimental toxicology. (6)
Review activity for Immunopharmacology and immunotoxicology. (5)
Review activity for Journal of biochemical and molecular toxicology. (17)
Review activity for Journal of biologically active products from nature. (1)
Review activity for Journal of food biochemistry. (2)
Review activity for Journal of herbs, spices & medicinal plants. (1)
Review activity for Journal of medicinal food. (5)
Review activity for Journal of pharmacy and pharmacology. (5)
Review activity for Journal of Taibah University for Science. (1)
Review activity for Journal of the science of food and agriculture. (2)
Review activity for Journal of trace elements in medicine and biology. (1)
Review activity for Life sciences. (4)
Review activity for Natural product communications. (4)
Review activity for Natural product research (2)
Review activity for Nutritional neuroscience (1)
Review activity for Pharmaceutical biology. (4)
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Review activity for PloS one. (4)
Review activity for Renal failure. (1)
Review activity for South African journal of botany. (2)
Review activity for Toxicology (1)
Review activity for Toxicology mechanisms and methods. (2)
Review activity for Toxicology reports. (2)
Review activity for Toxicology research (5)
Review activity for Toxin reviews. (1)