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Other IDs

ResearcherID: Q-4763-2018
Scopus Author ID: 56448985400
Loop profile: 860361

Keywords

extracellular vesicles, MASLD, T2DM, Pancreatic islets, Hepatocytes, Macrophages, Insulin resistance, Inflammation, beta-cell

Activities

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Employment (1)

Instituto de Investigaciones Biomédicas Sols-Morreale: Madrid, ES

Postdoctoral researcher (Metabolic and Immune Diseases)
Employment
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Works (24)

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk

Nature Communications
2024-11-28 | Journal article
DOI: 10.1038/s41467-024-54080-w
Part of ISSN: 2041-1723
Contributors: PILAR; Laura Ruiz; Cintia Folgueira; Patricia Rada Llano; Beatriz Gomez-Santos; Maite Solas; Ana B. Hitos; Joss Field; Vera Francisco; Carmen Escalona-Garrido et al.
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH

Redox Biology
2024-02 | Journal article
DOI: 10.1016/j.redox.2024.103027
Part of ISSN: 2213-2317
Contributors: Raquel Fernández-Ginés; José Antonio Encinar; Maribel Escoll; Daniel Carnicero-Senabre; José Jiménez-Villegas; Ángel J. García-Yagüe; Águeda González-Rodríguez; Irma Garcia-Martinez; Ángela M Valverde; Ana I. Rojo et al.
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

An altered expression of miR‐376a‐3p and miR‐20a‐5p in peripheral blood exosomes regulates the autophagy and inflammatory systemic substrates, and relates to the smoking habit and age in Crohn's disease

The FASEB Journal
2024-01-31 | Journal article
DOI: 10.1096/fj.202301761R
Contributors: Esther Caparrós; Irma García‐Martinez; Pedro Zapater; Lucía Madero; Ángela M. Valverde; Ana Gutiérrez; Rubén Francés
Source: check_circle
Crossref

Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance

JHEP Reports
2023-08 | Journal article
DOI: 10.1016/j.jhepr.2023.100756
Contributors: Irma Garcia-Martinez; Rosa Alen; Laura Pereira; Adrián Povo-Retana; Alma M. Astudillo; Ana B. Hitos; Isabel Gomez-Hurtado; Eduardo Lopez-Collazo; Lisardo Boscá; Rubén Francés et al.
Source: check_circle
Crossref

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition

Redox Biology
2023-07 | Journal article
DOI: 10.1016/j.redox.2023.102741
Part of ISSN: 2213-2317
Contributors: Vitor Ferreira; Cintia Folgueira; María García-Altares; Maria Guillén; Mónica Ruíz-Rosario; Giada DiNunzio; Irma Garcia-Martinez; Rosa Alen; Christoph Bookmeyer; John G. Jones et al.
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro

Redox Biology
2021-12 | Journal article
DOI: 10.1016/j.redox.2021.102171
Part of ISSN: 2213-2317
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells

Journal of Pharmacology and Experimental Therapeutics
2020-09 | Journal article
DOI: 10.1124/jpet.119.264481
Part of ISSN: 0022-3565
Part of ISSN: 1521-0103
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.

Frontiers in medicine
2020-08-11 | Journal article
DOI: 10.3389/fmed.2020.00395
PMID: 32850903
PMC: PMC7431466
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Impact Of Global Ptp1b Deficiency On The Gut Barrier Permeability During Nash In Mice

Molecular Metabolism
2020-02 | Journal article
DOI: 10.1016/j.molmet.2020.01.018
Part of ISSN: 2212-8778
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 2)‎

Impact of Bacterial Translocation on Sarcopenia in Patients with Decompensated Cirrhosis

Nutrients
2019-10-05 | Journal article
DOI: 10.3390/nu11102379
Part of ISSN: 2072-6643
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 2)‎

Ammonia-Induced Brain Edema Requires Macrophage and T Cell Expression of Toll-Like Receptor 9

Cellular and Molecular Gastroenterology and Hepatology
2019-08 | Journal article
DOI: 10.1016/j.jcmgh.2019.08.002
ISSN: 2352-345X
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

A leukocyte activation test identifies food items which induce release of DNA by innate immune peripheral blood leucocytes

Nutrition & metabolism
2018 | Journal article
DOI: 10.1186/s12986-018-0260-4
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis

Cell metabolism
2018 | Journal article
DOI: 10.1016/j.cmet.2018.01.007
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis

Liver international : official journal of the International Association for the Study of the Liver
2018 | Journal article
DOI: 10.1111/liv.13551
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 2)‎

SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress

Antioxidants & redox signaling
2018 | Journal article
DOI: 10.1089/ars.2017.7373
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis

Liver international : official journal of the International Association for the Study of the Liver
2018 | Journal article
DOI: 10.1111/liv.13890
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway

Journal of hepatology
2018 | Journal article
DOI: 10.1016/j.jhep.2018.04.004
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

The Journal of clinical investigation
2016 | Journal article
DOI: 10.1172/JCI83885
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis

Journal of hepatology
2015 | Journal article
DOI: 10.1016/j.jhep.2014.08.027
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

DNA: adding injury to insult

Hepatology (Baltimore, Md.)
2015 | Journal article
DOI: 10.1002/hep.27398
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 4)‎

Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice

Mucosal immunology
2015 | Journal article
DOI: 10.1038/mi.2014.84
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Therapeutic Opportunities in Damage-Associated Molecular Pattern-Driven Metabolic Diseases

Antioxidants & redox signaling
2015 | Journal article
DOI: 10.1089/ars.2015.6383
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Use of proton pump inhibitors decrease cellular oxidative burst in patients with decompensated cirrhosis

Journal of gastroenterology and hepatology
2015 | Journal article
DOI: 10.1111/jgh.12667
Source: Self-asserted source
IRMA GARCIA-MARTINEZ
grade
Preferred source (of 3)‎

Beta-adrenergic receptor 1 selective antagonism inhibits norepinephrine-mediated TNF-alpha downregulation in experimental liver cirrhosis

PloS one
2012 | Journal article
DOI: 10.1371/journal.pone.0043371
Source: Self-asserted source
IRMA GARCIA-MARTINEZ

Peer review (4 reviews for 3 publications/grants)

Review activity for Biology. (1)
Review activity for FEBS open bio. (1)
Review activity for Journal of extracellular biology. (2)
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