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Works (7)

Protocol for functional screening of CFTR-targeted genetic therapies in patient-derived organoids using DETECTOR deep-learning-based analysis

STAR Protocols
2025-03 | Journal article
DOI: 10.1016/j.xpro.2024.103593
Contributors: Mattijs Bulcaen; Ronald B. Liu; Kasper Gryspeert; Sam Thierie; Anabela S. Ramalho; François Vermeulen; Xavier Casadevall I Solvas; Marianne S. Carlon
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New insights into thecis-regulation of theCFTRgene in pancreatic cells

2025-01-19 | Preprint
DOI: 10.1101/2025.01.14.632890
Contributors: Clara Blotas; Anaïs Le Nabec; Mégane Collobert; Mattijs Bulcaen; Marianne S. Carlon; Claude Férec; Stéphanie Moisan
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Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

Cell Reports Medicine
2024-05 | Journal article
DOI: 10.1016/j.xcrm.2024.101544
Part of ISSN: 2666-3791
Contributors: Mattijs Bulcaen; Phéline Kortleven; Ronald B. Liu; Giulia Maule; Elise Dreano; Mairead Kelly; Marjolein M. Ensinck; Sam Thierie; Maxime Smits; Matteo Ciciani et al.
Source: Self-asserted source
Mattijs Bulcaen

Genetic surgery for a cystic fibrosis-causing splicing mutation

Molecular Therapy - Methods & Clinical Development
2024-03 | Journal article
DOI: 10.1016/j.omtm.2023.101177
Part of ISSN: 2329-0501
Contributors: Mattijs Bulcaen; Marianne Carlon
Source: Self-asserted source
Mattijs Bulcaen

Nanoblades allow high-level genome editing in murine and human organoids

Molecular Therapy - Nucleic Acids
2023-09 | Journal article
DOI: 10.1016/j.omtn.2023.06.004
Part of ISSN: 2162-2531
Contributors: Victor Tiroille; Adrien Krug; Emma Bokobza; Michel Kahi; Mattijs Bulcaen; Marjolein M. Ensinck; Maarten H. Geurts; Delilah Hendriks; François Vermeulen; Frédéric Larbret et al.
Source: Self-asserted source
Mattijs Bulcaen

Point-of-care therapeutic drug monitoring of adalimumab by integrating a FO-SPR biosensor in a self-powered microfluidic cartridge

Biosensors and Bioelectronics
2022-06 | Journal article
DOI: 10.1016/j.bios.2022.114125
Contributors: Jia-Huan Qu; Henry Ordutowski; Charlotte Van Tricht; Ruben Verbruggen; Alicia Barcenas Gallardo; Mattijs Bulcaen; Marta Ciwinska; Carolina Gutierrez Cisneros; Christophe Devriese; Sona Guluzade et al.
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Crossref

Rewriting CFTR to cure cystic fibrosis

Progress in Molecular Biology and Translational Science
2021 | Book chapter
DOI: 10.1016/bs.pmbts.2020.12.018
Part of ISBN: 9780323853019
Part of ISSN: 1877-1173
Contributors: Giulia Maule; Marjolein Ensinck; Mattijs Bulcaen; Marianne S. Carlon
Source: Self-asserted source
Mattijs Bulcaen

Peer review (1 review for 1 publication/grant)

Review activity for Gene therapy. (1)
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