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ResearcherID: Q-6588-2018

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Works (14)

A synthesis-enabled relative configurational assignment of the C31–C46 region of hemicalide

Chemical Communications
2022 | Journal article
DOI: 10.1039/D2CC01802K
Contributors: Tegan P. Stockdale; Nelson Y. S. Lam; Ian Paterson
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Deep‐Sea Discovery and Detective Work: Towards Solving the Hemicalide Structural Enigma through Computational NMR Analysis and Stereocontrolled Synthesis

European Journal of Organic Chemistry
2022-07-07 | Journal article
DOI: 10.1002/ejoc.202200467
Contributors: Nelson Y. S. Lam; Ian Paterson
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Conquering peaks and illuminating depths: developing stereocontrolled organic reactions to unlock nature's macrolide treasure trove

Chemical Communications
2021 | Journal article
DOI: 10.1039/D1CC00442E
Contributors: Nelson Y. S. Lam; Tegan P. Stockdale; Matthew J. Anketell; Ian Paterson
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Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes

Proceedings of the National Academy of Sciences
2021-12-21 | Journal article
DOI: 10.1073/pnas.2112261118
Contributors: Ankit Rai; Tianyang Liu; Eugene A. Katrukha; Juan Estévez-Gallego; Szymon W. Manka; Ian Paterson; J. Fernando Díaz; Lukas C. Kapitein; Carolyn A. Moores; Anna Akhmanova
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Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A

Chemical Communications
2020 | Journal article
DOI: 10.1039/D0CC03055D
Contributors: Ikenna E. Ndukwe; Xiao Wang; Nelson Y. S. Lam; Kristaps Ermanis; Kelsey L. Alexander; Matthew J. Bertin; Gary E. Martin; Garrett Muir; Ian Paterson; Robert Britton et al.
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Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents

Chemical Communications
2020 | Journal article
DOI: 10.1039/C9CC09050A
Contributors: Talia R. Pettigrew; Rachel J. Porter; Stephen J. Walsh; Michael P. Housden; Nelson Y. S. Lam; Jason S. Carroll; Jeremy S. Parker; David R. Spring; Ian Paterson
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Total synthesis of the actinoallolides and a designed photoaffinity probe for target identification

Organic & Biomolecular Chemistry
2020 | Journal article
DOI: 10.1039/D0OB01831G
Contributors: Matthew J. Anketell; Theodore M. Sharrock; Ian Paterson
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Stereocontrolled Synthesis as an Enabling Tool for the Configurational Assignment of Marine Polyketide Natural Products

European Journal of Organic Chemistry
2020-05-03 | Journal article
DOI: 10.1002/ejoc.201901243
Contributors: Nelson Y. S. Lam; Ian Paterson
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A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides

Angewandte Chemie
2020-01-20 | Journal article
DOI: 10.1002/ange.201914042
Contributors: Matthew J. Anketell; Theodore M. Sharrock; Ian Paterson
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A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides

Angewandte Chemie International Edition
2020-01-20 | Journal article
DOI: 10.1002/anie.201914042
Contributors: Matthew J. Anketell; Theodore M. Sharrock; Ian Paterson
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A counterintuitive stereochemical outcome from a chelation-controlled vinylmetal aldehyde addition leads to the configurational reassignment of phormidolide A

Chemical Communications
2019 | Journal article
DOI: 10.1039/C9CC05067A
Contributors: Nelson Y. S. Lam; Garrett Muir; Venugopal Rao Challa; Robert Britton; Ian Paterson
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A synthesis-enabled relative stereochemical assignment of the C1–C28 region of hemicalide

Chemical Communications
2018 | Journal article
DOI: 10.1039/C8CC00933C
Contributors: Bing Yuan Han; Nelson Y. S. Lam; Callum I. MacGregor; Jonathan M. Goodman; Ian Paterson
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Toward aplyronine payloads for antibody–drug conjugates: total synthesis of aplyronines A and D

Organic & Biomolecular Chemistry
2018 | Journal article
DOI: 10.1039/C7OB03204H
Contributors: Nika Anžiček; Simon Williams; Michael P. Housden; Ian Paterson
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Toward the total synthesis of patellazole B: synthesis of an advanced C1–C25 fragment corresponding to the macrocyclic skeleton

Organic & Biomolecular Chemistry
2018 | Journal article
DOI: 10.1039/C8OB01621F
Contributors: Andrew W. Phillips; Matthew J. Anketell; Tudor Balan; Nelson Y. S. Lam; Simon Williams; Ian Paterson
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