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Employment (1)

Cedars-Sinai Medical Center: Los Angeles, CA, US

2007 to present (Medicine)
Employment
Source: Self-asserted source
Talin Haritunians

Education and qualifications (2)

Cedars Sinai Medical Center: Los Angeles, CA, US

2005 to 2007 | Post-doc (Hem/Onc)
Education
Source: Self-asserted source
Talin Haritunians

University of California Los Angeles: Los Angeles, CA, US

2004 | PhD (Human Genetics)
Education
Source: Self-asserted source
Talin Haritunians

Works (16)

Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics

Inflammatory Bowel Diseases
2025-01-06 | Journal article
DOI: 10.1093/ibd/izae269
Contributors: Greg Gibson; John D Rioux; Judy H Cho; Talin Haritunians; Akshaya Thoutam; Maria T Abreu; Steven R Brant; Subra Kugathasan; Jacob L McCauley; Mark Silverberg et al.
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Crossref

Development of a deep learning algorithm for Paneth cell density quantification for inflammatory bowel disease

eBioMedicine
2024-12 | Journal article
DOI: 10.1016/j.ebiom.2024.105440
Contributors: Liang-I Kang; Kathryn Sarullo; Jon N. Marsh; Liang Lu; Pooja Khonde; Changqing Ma; Talin Haritunians; Angela Mujukian; Emebet Mengesha; Dermot P.B. McGovern et al.
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Crossref

Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis

Journal of Crohn's and Colitis
2024-12-02 | Journal article
DOI: 10.1093/ecco-jcc/jjae105
Contributors: Changqing Ma; Talin Haritunians; Anas K Gremida; Gaurav Syal; Janaki Shah; Shaohong Yang; Claudia Ramos Del Aguila de Rivers; Chad E Storer; Ling Chen; Emebet Mengesha et al.
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Crossref

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction

Science Immunology
2024-11-08 | Journal article
DOI: 10.1126/sciimmunol.adi7907
Contributors: Shengxiang Sun; Miki Hodel; Xiang Wang; Javier De Vicente; Talin Haritunians; Anketse Debebe; Chen-Ting Hung; Changqing Ma; Atika Malique; Hoang N. Nguyen et al.
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Crossref

Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease.

Gastroenterology
2024-03-13 | Journal article
DOI: 10.1053/j.gastro.2024.02.026
PMID: 38490347
Contributors: Khrom M; Long M; Dube S; Robbins L; Botwin GJ; Yang S; Mengesha E; Li D; Naito T; Bonthala NN et al.
Source: Self-asserted source
Talin Haritunians

Allogeneic bone marrow transplantation for patients with treatment-refractory Crohn's Disease

Heliyon
2024-01 | Journal article
DOI: 10.1016/j.heliyon.2024.e24026
Contributors: George B. McDonald; Ole J.B. Landsverk; Dermot P.B. McGovern; Anders Aasebø; Vemund Paulsen; Talin Haritunians; Henrik M. Reims; Bernadette M. McLaughlin; Timothy Zisman; Dalin Li et al.
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Crossref

NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction

Science Translational Medicine
2024-01-03 | Journal article
DOI: 10.1126/scitranslmed.abq4145
Contributors: Atika Malique; Shengxiang Sun; Kanta Chandwe; Beatrice Amadi; Talin Haritunians; Umang Jain; Brian D. Muegge; Jennifer Frein; Yo Sasaki; Amanda Foster et al.
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Crossref

Sex-Dimorphic Analyses Identify Novel and Sex-Specific Genetic Associations in Inflammatory Bowel Disease.

Inflammatory bowel diseases
2023-10-01 | Journal article | Author
DOI: 10.1093/ibd/izad089
PMID: 37262302
PMC: PMC10547236
Contributors: Khrom M; Li D; Naito T; Ho-Su Lee; Botwin GJ; Potdar AA; Boucher G; NIDDK Inflammatory Bowel Disease Genetics Consortium; International Inflammatory Bowel Disease Genetics Consortium; Yang S et al.
Source: Self-asserted source
Talin Haritunians

Genetic variation in environmental enteropathy and stunting in Zambian children: A pilot genome wide association study using the H3Africa chip

PLOS ONE
2023-09-27 | Journal article
DOI: 10.1371/journal.pone.0291311
Contributors: Monica N. Mweetwa; Xiang Zhu; Talin Haritunians; Shishir Dube; Kanta Chandwe; Beatrice Amadi; Kanekwa Zyambo; Ta-Chiang Liu; Dermot McGovern; Paul Kelly
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Crossref

Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.

Gut
2023-04-20 | Journal article
DOI: 10.1136/gutjnl-2023-329689
PMID: 37080587
PMC: PMC11036449
Contributors: Akhlaghpour M; Haritunians T; More SK; Thomas LS; Stamps DT; Dube S; Li D; Yang S; Landers CJ; Mengesha E et al.
Source: Self-asserted source
Talin Haritunians

Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations.

Human molecular genetics
2021-02-08 | Journal article
DOI: 10.1093/hmg/ddab017
PMID: 33555323
Source: Self-asserted source
Talin Haritunians

Inflamed ulcerative colitis regions associated to MRGPRX2-mediated mast cell degranulation and cell activation modules, defining a new therapeutic target.

Gastroenterology
2021-01-06 | Journal article
DOI: 10.1053/j.gastro.2020.12.076
PMID: 33421512
Source: Self-asserted source
Talin Haritunians

Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease.

Gastroenterology
2020-11-05 | Journal article
DOI: 10.1053/j.gastro.2020.10.041
PMID: 33160965
Source: Self-asserted source
Talin Haritunians

Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease.

Gastroenterology
2020-10-21 | Journal article
DOI: 10.1053/j.gastro.2020.10.019
PMID: 33098885
Source: Self-asserted source
Talin Haritunians

Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

JCI Insight
2020-10-15 | Journal article
DOI: 10.1172/jci.insight.140978
Contributors: Laxmi Sunuwar; Azra Frkatović; Sodbo Sharapov; Qinchuan Wang; Heather M. Neu; Xinqun Wu; Talin Haritunians; Fengyi Wan; Sarah Michel; Shaoguang Wu et al.
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Crossref

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

PLOS Genetics
2018-05-24 | Journal article
DOI: 10.1371/journal.pgen.1007329
Contributors: Manuel A. Rivas; Scott M. Williams; Brandon E. Avila; Jukka Koskela; Hailiang Huang; Christine Stevens; Matti Pirinen; Talin Haritunians; Benjamin M. Neale; Mitja Kurki et al.
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Crossref
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