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https://u1034.bordeaux.inserm.fr/

Keywords

vascular biology, Wnt/frizzled, angiogenesis

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Employment (2)

University of Bordeaux: Bordeaux, FR

2010-09 to present | PU (Inserm U1034 and UFR des Sciences Pharmaceutiques de Bordeaux)
Employment
Source: Self-asserted source
Pascale Dufourcq

University of Bordeaux: Bordeaux, FR

2001 to 2010 | MCU (Inserm )
Employment
Source: Self-asserted source
Pascale Dufourcq

Works (47)

ROR2/PCP a New Pathway Controlling Endothelial Cell Polarity Under Flow Conditions

Arteriosclerosis, Thrombosis, and Vascular Biology
2023-07 | Journal article | Author
DOI: 10.1161/atvbaha.123.319106
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Contributors: Pauline Bougaran; Marie-Lise Bats; Valentin Delobel; Sebastien Rubin; Juliette Vaurs; Thierry Couffinhal; cecile Duplàa; Pascale Dufourcq
Source: Self-asserted source
Pascale Dufourcq

Decrease of Pdzrn3 is required for heart maturation and protects against heart failure

Scientific Reports
2022-12 | Newspaper article
DOI: 10.1038/s41598-021-03795-7
Part of ISSN: 2045-2322
Source: Self-asserted source
Pascale Dufourcq

Increased Capillary Permeability in Heart Induces Diastolic Dysfunction Independently of Inflammation, Fibrosis, or Cardiomyocyte Dysfunction

Arteriosclerosis, Thrombosis, and Vascular Biology
2022-06 | Journal article
DOI: 10.1161/atvbaha.121.317319
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Contributors: Alice Abelanet; Marion Camoin; Sebastien Rubin; Pauline Bougaran; Valentin Delobel; Mathieu Pernot; Isabelle FORFAR; Céline Guilbeau-Frugier; Céline Galès; Marie-Lise Bats et al.
Source: Self-asserted source
Pascale Dufourcq

PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice

Arteriosclerosis, Thrombosis, and Vascular Biology
2022-05 | Journal article
DOI: 10.1161/atvbaha.122.317431
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Contributors: Sebastien Rubin; Pauline Bougaran; Soizic Martin; Alice Abelanet; Valentin Delobel; Mathieu Pernot; Sylvie Jeanningros; Marie-Lise Bats; Christian Combe; Pascale Dufourcq et al.
Source: Self-asserted source
Pascale Dufourcq

Wnt/frizzled Signaling in Endothelium: A Major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity

Cold Spring Harbor Perspectives in Medicine
2022-01-24 | Journal article
DOI: 10.1101/cshperspect.a041219
Part of ISSN: 2157-1422
Source: Self-asserted source
Pascale Dufourcq

Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis

Journal of Cerebral Blood Flow & Metabolism
2021-10-13 | Journal article
DOI: 10.1177/0271678x211048981
Part of ISSN: 0271-678X
Part of ISSN: 1559-7016
Source: Self-asserted source
Pascale Dufourcq

Fluid Shear Stress Sensing by the Endothelial Layer.

Frontiers in physiology
2020-07 | Journal article
DOI: 10.3389/fphys.2020.00861
PMID: 32848833
PMC: PMC7396610
Contributors: Roux E; Bougaran P; Dufourcq P; Couffinhal T
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Repression of Pdzrn3 is required for heart maturation and protects against heart failure

2020-07 | Preprint
DOI: 10.1101/2020.07.29.226597
OTHER-ID:

PPR193876
Contributors: Pernot M; Jaspard-vinassa B; Abelanet A; Rubin S; Forfar I; Jeanningros S; Cetran L; Yu MH; Balse E; Hatem S et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Therapies targeting Frizzled-7/β-catenin pathway prevent the development of pathological angiogenesis in an ischemic retinopathy model.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2019-11 | Journal article
DOI: 10.1096/fj.201901886r
PMID: 31914666
Contributors: Bats ML; Bougaran P; Peghaire C; Gueniot F; Abelanet A; Chan H; Séguy C; Jeanningros S; Jaspard-Vinassa B; Couffinhal T et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability.

Science signaling
2017-01 | Journal article
DOI: 10.1126/scisignal.aag3209
PMID: 28143902
Contributors: Sewduth RN; Kovacic H; Jaspard-Vinassa B; Jecko V; Wavasseur T; Fritsch N; Pernot M; Jeaningros S; Roux E; Dufourcq P et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling.

Arteriosclerosis, thrombosis, and vascular biology
2016-10 | Journal article
DOI: 10.1161/atvbaha.116.307926
PMID: 27758766
Contributors: Peghaire C; Bats ML; Sewduth R; Jeanningros S; Jaspard B; Couffinhal T; Duplàa C; Dufourcq P
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway.

Molecular biology of the cell
2016-01 | Journal article
DOI: 10.1091/mbc.e14-08-1332
PMID: 26792835
PMC: PMC4791138
Contributors: Guillabert-Gourgues A; Jaspard-Vinassa B; Bats ML; Sewduth RN; Franzl N; Peghaire C; Jeanningros S; Moreau C; Roux E; Larrieu-Lahargue F et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling.

Nature communications
2014-09 | Journal article
DOI: 10.1038/ncomms5832
PMID: 25198863
Contributors: Sewduth RN; Jaspard-Vinassa B; Peghaire C; Guillabert A; Franzl N; Larrieu-Lahargue F; Moreau C; Fruttiger M; Dufourcq P; Couffinhal T et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Frizzled7 controls vascular permeability through the Wnt-canonical pathway and cross-talk with endothelial cell junction complexes.

Cardiovascular research
2014-05 | Journal article
DOI: 10.1093/cvr/cvu133
PMID: 24866384
Contributors: Ferreira Tojais N; Peghaire C; Franzl N; Larrieu-Lahargue F; Jaspard B; Reynaud A; Moreau C; Couffinhal T; Duplàa C; Dufourcq P
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Frizzled 4 regulates arterial network organization through noncanonical Wnt/planar cell polarity signaling.

Circulation research
2011-11 | Journal article
DOI: 10.1161/circresaha.111.250936
PMID: 22076635
Contributors: Descamps B; Sewduth R; Ferreira Tojais N; Jaspard B; Reynaud A; Sohet F; Lacolley P; Allières C; Lamazière JM; Moreau C et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Secreted frizzled-related protein-1 improves postinfarction scar formation through a modulation of inflammatory response.

Arteriosclerosis, thrombosis, and vascular biology
2011-11 | Journal article
DOI: 10.1161/atvbaha.111.232280
PMID: 21836067
Contributors: Barandon L; Casassus F; Leroux L; Moreau C; Allières C; Lamazière JM; Dufourcq P; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Hypoxia preconditioned mesenchymal stem cells improve vascular and skeletal muscle fiber regeneration after ischemia through a Wnt4-dependent pathway.

Molecular therapy : the journal of the American Society of Gene Therapy
2010-06 | Journal article
DOI: 10.1038/mt.2010.108
PMID: 20551912
PMC: PMC2927059
Contributors: Leroux L; Descamps B; Tojais NF; Séguy B; Oses P; Moreau C; Daret D; Ivanovic Z; Boiron JM; Lamazière JM et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Mapping 3-dimensional neovessel organization steps using micro-computed tomography in a murine model of hindlimb ischemia-brief report.

Arteriosclerosis, thrombosis, and vascular biology
2009-09 | Journal article
DOI: 10.1161/atvbaha.109.192732
PMID: 19745199
PMC: PMC2941695
Contributors: Oses P; Renault MA; Chauvel R; Leroux L; Allières C; Séguy B; Lamazière JM; Dufourcq P; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Mouse models to study angiogenesis in the context of cardiovascular diseases.

Frontiers in bioscience (Landmark edition)
2009-01 | Journal article
DOI: 10.2741/3454
PMID: 19273276
Contributors: Couffinhal T; Dufourcq P; Barandon L; Leroux L; Duplaa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Estrogen-stimulated endothelial repair requires osteopontin.

Arteriosclerosis, thrombosis, and vascular biology
2008-09 | Journal article
DOI: 10.1161/atvbaha.108.167965
PMID: 18772499
Contributors: Leen LL; Filipe C; Billon A; Garmy-Susini B; Jalvy S; Robbesyn F; Daret D; Allières C; Rittling SR; Werner N et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Secreted frizzled-related protein-1 enhances mesenchymal stem cell function in angiogenesis and contributes to neovessel maturation.

Stem cells (Dayton, Ohio)
2008-08 | Journal article
DOI: 10.1634/stemcells.2008-0372
PMID: 18757297
Contributors: Dufourcq P; Descamps B; Tojais NF; Leroux L; Oses P; Daret D; Moreau C; Lamazière JM; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Epicardial deposition of endothelial progenitor and mesenchymal stem cells in a coated muscle patch after myocardial infarction in a murine model.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
2008-05 | Journal article
DOI: 10.1016/j.ejcts.2008.03.058
PMID: 18457957
Contributors: Derval N; Barandon L; Dufourcq P; Leroux L; Lamazière JM; Daret D; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation.

The American journal of pathology
2007-12 | Journal article
DOI: 10.2353/ajpath.2008.070130
PMID: 18156211
PMC: PMC2189632
Contributors: Dufourcq P; Leroux L; Ezan J; Descamps B; Lamazière JM; Costet P; Basoni C; Moreau C; Deutsch U; Couffinhal T et al.
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Beta-catenin nuclear activation: common pathway between Wnt and growth factor signaling in vascular smooth muscle cell proliferation?

Circulation research
2006-12 | Journal article
DOI: 10.1161/01.res.0000253139.82251.31
PMID: 17158343
Contributors: Couffinhal T; Dufourcq P; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Exact relevance of bone marrow cells in the healing process after myocardial infarction: analysis with a murine model of bone marrow cell transplantation.

The Canadian journal of cardiology
2005-05 | Journal article
PMID: 15940353
Contributors: Barandon L; Couffinhal T; Dufourcq P; Alzieu P; Moreau C; Daret D; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Involvement of FrzA/sFRP-1 and the Wnt/frizzled pathway in ischemic preconditioning.

Circulation research
2005-05 | Journal article
DOI: 10.1161/01.res.0000171895.06914.2c
PMID: 15920021
Contributors: Barandon L; Dufourcq P; Costet P; Moreau C; Allières C; Daret D; Dos Santos P; Daniel Lamazière JM; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

[Study of postmyocardial infarction scar-formation mechanisms: advantage of an experimental myocardial infarction model in mice].

The Canadian journal of cardiology
2004-12 | Journal article
PMID: 15614343
Contributors: Barandon L; Couffinhal T; Dufourcq P; Daret D; Allières C; Alzieu P; Deville C; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Gene therapy for chronic peripheral arterial disease: what role for the vascular surgeon?

Annals of vascular surgery
2004-11 | Journal article
DOI: 10.1007/s10016-004-0115-5
PMID: 15599638
Contributors: Barandon L; Leroux L; Dufourcq P; Plagnol P; Deville C; Duplaa C; Couffinhal T
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Repair of myocardial infarction by epicardial deposition of bone-marrow-cell-coated muscle patch in a murine model.

The Annals of thoracic surgery
2004-10 | Journal article
DOI: 10.1016/j.athoracsur.2003.12.078
PMID: 15464506
Contributors: Barandon L; Couffinhal T; Dufourcq P; Alzieu P; Daret D; Deville C; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo.

Cardiovascular research
2004-09 | Journal article
DOI: 10.1016/j.cardiores.2004.05.006
PMID: 15306229
Contributors: Ezan J; Leroux L; Barandon L; Dufourcq P; Jaspard B; Moreau C; Allières C; Daret D; Couffinhal T; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Frizzled A, a novel angiogenic factor: promises for cardiac repair.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
2004-01 | Journal article
DOI: 10.1016/s1010-7940(03)00506-2
PMID: 14690736
Contributors: Barandon L; Couffinhal T; Dufourcq P; Ezan J; Costet P; Daret D; Deville C; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA.

Circulation
2003-10 | Journal article
DOI: 10.1161/01.cir.0000093186.22847.4c
PMID: 14581414
Contributors: Barandon L; Couffinhal T; Ezan J; Dufourcq P; Costet P; Alzieu P; Leroux L; Moreau C; Dare D; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

FrzA, a secreted frizzled related protein, induced angiogenic response.

Circulation
2002-12 | Journal article
DOI: 10.1161/01.cir.0000039342.85015.5c
PMID: 12473558
Contributors: Dufourcq P; Couffinhal T; Ezan J; Barandon L; Moreau C; Daret D; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Vitronectin is up-regulated after vascular injury and vitronectin blockade prevents neointima formation.

Cardiovascular research
2002-03 | Journal article
DOI: 10.1016/s0008-6363(01)00547-8
PMID: 11922905
Contributors: Dufourcq P; Couffinhal T; Alzieu P; Daret D; Moreau C; Duplàa C; Bonnet J
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Kinetics of adventitial repair in the rat carotid model.

Coronary artery disease
2001-12 | Journal article
DOI: 10.1097/00019501-200112000-00007
PMID: 11811329
Contributors: Couffinhal T; Dufourcq P; Jaspard B; Daret D; Allières C; Alzieu P; Serre P; Bonnet J; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

[The mechanisms of angiogenesis. Medical and therapeutic applications].

La Revue de medecine interne
2001-11 | Journal article
DOI: 10.1016/s0248-8663(01)00472-6
PMID: 11817119
Contributors: Couffinhal T; Dufourcq P; Daret D; Duplaà C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Nitric oxide reduces vascular smooth muscle cell elastase activity through cGMP-mediated suppression of ERK phosphorylation and AML1B nuclear partitioning.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2000-04 | Journal article
DOI: 10.1096/fasebj.14.5.805
PMID: 10744637
Contributors: Mitani Y; Zaidi SH; Dufourcq P; Thompson K; Rabinovitch M
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis.

Mechanisms of development
2000-02 | Journal article
DOI: 10.1016/s0925-4773(99)00236-1
PMID: 10640709
Contributors: Jaspard B; Couffinhal T; Dufourcq P; Moreau C; Duplàa C
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Vitronectin expression and interaction with receptors in smooth muscle cells from human atheromatous plaque.

Arteriosclerosis, thrombosis, and vascular biology
1998-02 | Journal article
DOI: 10.1161/01.atv.18.2.168
PMID: 9484980
Contributors: Dufourcq P; Louis H; Moreau C; Daret D; Boisseau MR; Lamazière JM; Bonnet J
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Phenotypic modification of arterial smooth muscle cells in response to medial dissection.

Coronary artery disease
1997-03 | Journal article
DOI: 10.1097/00019501-199703000-00007
PMID: 9237026
Contributors: Dufourcq P; Louis H; Dandré F; Lavie J; Bonnet J; Lamazière JM
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

The integrin very late antigen-4 is expressed in human smooth muscle cell. Involvement of alpha 4 and vascular cell adhesion molecule-1 during smooth muscle cell differentiation.

Circulation research
1997-02 | Journal article
DOI: 10.1161/01.res.80.2.159
PMID: 9012738
Contributors: Duplàa C; Couffinhal T; Dufourcq P; Llanas B; Moreau C; Bonnet J
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Membrane thrombomodulin levels are decreased during hypoxia and restored by cAMP and IBMX.

Thrombosis research
1995-02 | Journal article
DOI: 10.1016/0049-3848(95)91617-t
PMID: 7537920
Contributors: Dufourcq P; Seigneur M; Pruvost A; Dumain P; Belloc F; Amiral J; Boisseau MR
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Influence of pentoxifylline on membrane thrombomodulin levels in endothelial cells submitted to hypoxic conditions.

Journal of cardiovascular pharmacology
1995-01 | Journal article
DOI: 10.1097/00005344-199500252-00018
PMID: 8699869
Contributors: Seigneur M; Dufourcq P; Belloc F; Lenoble M; Renard M; Boisseau MR
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Plasma thrombomodulin levels increase with the severity of the diabetic retinopathy.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
1994-10 | Journal article
DOI: 10.1097/00001721-199410000-00026
PMID: 7865695
Contributors: Seigneur M; Dufourcq P; Gin H; Delafaye C; Amiral J; Pruvost A; Boisseau MR
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Plasma thrombomodulin: new approach of endothelium damage.

International angiology : a journal of the International Union of Angiology
1993-12 | Journal article
PMID: 8207313
Contributors: Seigneur M; Dufourcq P; Conri C; Constans J; Mercie P; Pruvost A; Boisseau M
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

Levels of plasma thrombomodulin are increased in atheromatous arterial disease.

Thrombosis research
1993-09 | Journal article
DOI: 10.1016/0049-3848(93)90116-6
PMID: 8134903
Contributors: Seigneur M; Dufourcq P; Conri C; Constans J; Mercié P; Pruvost A; Amiral J; Midy D; Baste JC; Boisseau MR
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central

[Evidence of elevated soluble plasma thrombomodulin in atherosclerosis]

Journal des maladies vasculaires
1993-01 | Journal article
PMID: 8394402
Contributors: Conri C; Seigneur M; Constans J; Mercier P; Baste JC; Dufourcq P; Boisseau MR
Source: Self-asserted source
Pascale Dufourcq via Europe PubMed Central
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