Personal information

Molecula dynamics, Quantum mechanics, Enzymatic reactions, Protein structure, Docking
Colombia

Activities

Education and qualifications (1)

Universidad de Zaragoza: Zaragoza, Aragón, ES

2006 to 2012 | PhD (Biochemistry )
Education
Source: Self-asserted source
Isaias Lans Vargas

Works (18)

Factors influencing citizens’ adoption of e-government: an empirical validation in a Developing Latin American Country

Public Management Review
2024-01-02 | Journal article
Contributors: Juan Pablo Ramirez-Madrid; Manuela Escobar-Sierra; Isaias Lans-Vargas; Juan Manuel Montes Hincapie
Source: check_circle
Crossref

In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

PLOS Computational Biology
2020-08-14 | Journal article
Contributors: Isaias Lans; Alexander MacKerell; Ernesto Anoz-Carbonell; Karen Palacio-Rodríguez; José Antonio Aínsa; Milagros Medina; Pilar Cossio
Source: check_circle
Crossref

In silicodiscovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

2020-04-22 | Preprint
Contributors: Isaias Lans; Ernesto Anoz-Carbonell; Karen Palacio-Rodríguez; José Antonio Aínsa; Milagros Medina; Pilar Cossio
Source: check_circle
Crossref

Entropy drives the insertion of ibuprofen into model membranes

Physical Chemistry Chemical Physics
2018 | Journal article
Contributors: Natalia Rojas-Valencia; Isaias Lans; Marcela Manrique-Moreno; C. Z. Hadad; Albeiro Restrepo
Source: check_circle
Crossref

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases.

Journal of enzyme inhibition and medicinal chemistry
2018-12 | Journal article
Contributors: Sebastián M; Anoz-Carbonell E; Gracia B; Cossio P; Aínsa JA; Lans I; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Shining light on an mGlu5 photoswitchable NAM: A theoretical perspective

Current Neuropharmacology
2016 | Journal article
EID:

2-s2.0-84975690920

Contributors: Dalton, J.A.R.; Lans, I.; Rovira, X.; Malhaire, F.; Gómez-Santacana, X.; Pittolo, S.; Gorostiza, P.; Llebaria, A.; Goudet, C.; Pin, J.-P. et al.
Source: Self-asserted source
Isaias Lans Vargas via Scopus - Elsevier

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective.

Current Neuropharmacology
2016 | Journal article
Contributors: Dalton JA; Lans I; Rovira X; Malhaire F; Gómez-Santacana X; Pittolo S; Gorostiza P; Llebaria A; Goudet C; Pin JP et al.
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Spin Densities in Flavin Analogs within a Flavoprotein.

Biophysical journal
2016-02 | Journal article
Contributors: Martínez JI; Frago S; Lans I; Alonso PJ; García-Rubio I; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.

BMC bioinformatics
2015 | Journal article
Contributors: Dalton JA; Lans I; Giraldo J
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures.

Journal of structural biology
2015-12 | Journal article
Contributors: Lans I; Dalton JA; Giraldo J
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Structural insights into the synthesis of FMN in prokaryotic organisms.

Acta crystallographica. Section D, Biological crystallography
2015-12 | Journal article
Contributors: Herguedas B; Lans I; Sebastián M; Hermoso JA; Martínez-Júlvez M; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central
grade
Preferred source (of 2)‎

Selective Protonation of Acidic Residues Triggers Opsin Activation.

The journal of physical chemistry. B
2015-07 | Journal article
Contributors: Lans I; Dalton JA; Giraldo J
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Theoretical study of the mechanism of the hydride transfer between ferredoxin-NADP+ reductase and NADP+: the role of Tyr303.

Journal of the American Chemical Society
2012-12 | Journal article
Contributors: Lans I; Medina M; Rosta E; Hummer G; Garcia-Viloca M; Lluch JM; González-Lafont À
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Understanding the FMN cofactor chemistry within the Anabaena Flavodoxin environment.

Biochimica et biophysica acta
2012-12 | Journal article
Contributors: Lans I; Frago S; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

The transient catalytically competent coenzyme allocation into the active site of Anabaena ferredoxin NADP+ -reductase.

European biophysics journal : EBJ
2012-01 | Journal article
Contributors: Peregrina JR; Lans I; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Mechanism of the hydride transfer between Anabaena Tyr303Ser FNR(rd)/FNR(ox) and NADP+/H. A combined pre-steady-state kinetic/ensemble-averaged transition-state theory with multidimensional tunneling study.

The journal of physical chemistry. B
2010-03 | Journal article
Contributors: Lans I; Peregrina JR; Medina M; Garcia-Viloca M; González-Lafont A; Lluch JM
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface.

Biochimica et biophysica acta
2010-02 | Journal article
Contributors: Frago S; Lans I; Navarro JA; Hervás M; Edmondson DE; De la Rosa MA; Gómez-Moreno C; Mayhew SG; Medina M
Source: Self-asserted source
Isaias Lans Vargas via Europe PubMed Central

Molecular design of inhibitors against the M<sup>pro</sup>protein of the severe acute respiratory syndrome (SARS) virus

New Journal of Chemistry
2008 | Journal article
EID:

2-s2.0-40349100446

Contributors: Olivero-Verbel, J.; Lans, I.; Martinez, E.; Ospino, I.; Padilla, A.; Vivas-Reyes, R.
Source: Self-asserted source
Isaias Lans Vargas via Scopus - Elsevier