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MetaBioGenX Pvt Ltd Jhansi India

Other IDs

Scopus Author ID: 44261747200
ResearcherID: M-2546-2016

Keywords

Enzyme Therapeutics, Proteomics and Biophysical Characterization

Biography

I focus primarily on understanding promiscuous nature of serine protease and therapeutic translational opportunity precisely vascular thrombolytic disorders as a thrombolytic agent. My research interest lies in exploring protein biochemistry and biophysical studies of therapeutic enzymes. Currently, I am working to explore drug delivery strategies across the blood-brain barrier (BBB) using native transport mechanisms. I am a 2005 Pharma graduate from Uttar Pradesh Technical University, completed M.Tech Biotechnology from the West Bengal University of Technology, Kolkata and Ph.D. from Acharya Nagarjuna University, Guntur Andhra Pradesh. I have received DBT fellowship from M.Tech. Biotechnology program (2006-2008) and DST-National Post-Doctoral Fellowship (2016-2018).

Activities

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Employment (6)

MetaBioGenX Pvt Ltd: Jhansi, Uttar Pradesh, IN

2023-01-01 to present | Director (Research and Development)
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

American University School of Medicine : Oranjestad, AW

2020-09-03 to 2022-12-24 | Assistant Professor and Research Coordinator (Medicine)
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

Centre for Molecular Biology Research (CMBR): Bhopal, Madhya Pradesh, IN

2019-12-01 to 2020-08-31 | Research Consultant (Research )
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

Rejuvenation Therapeutic Corp: San Diego, California, US

2018-09-03 to 2019-11-25 | Research Consultant (Research )
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

RVR and JC College of Engineering: Guntur, Andhra Pradesh, IN

2008-11-06 to 2015-06-05 | Assistant Professor (Biotechnology)
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

ASA Biotech Pvt Ltd: Baddi, Himanchal Pradesh, IN

2005-06-15 to 2006-07-25 | Assistant Production Engineer (Manufacturing )
Employment
Source: Self-asserted source
Dr Mahendra Kumar Verma

Education and qualifications (4)

MetaBioGenX Pvt Ltd: Jhansi, Uttar Pradesh, IN

Director (Research and Development)
Qualification
Source: Self-asserted source
Dr Mahendra Kumar Verma

Indian Institute of Science Education and Reserch : Bhopal , Madhya Pradesh, IN

2016-07-18 to present | Post Doctoral Fellow (Biological Science )
Education
Source: Self-asserted source
Dr Mahendra Kumar Verma

West Bengal State University: Kolkata, West Bengal, IN

2006-08-01 to 2008-07-31 | MTech (Biotechnology)
Education
Source: Self-asserted source
Dr Mahendra Kumar Verma

Uttar Pradesh Technical University: Lucknow, Uttar Pradesh, IN

2001-10-01 to 2005-05-31 | BPharma (Pharmaceutical Sciences)
Education
Source: Self-asserted source
Dr Mahendra Kumar Verma

Funding (1)

Design of an earthworm fibrinolytic enzyme (EFE) analogue with enhanced receptor binding selectivity, structure rationale, and therapeutic implications

2016-07 to 2018-06 | Grant
Science Engineeirng and Research Board (SERB) (New Delhi, India, IN)
URL: https://research.iiserb.ac.in/pages/projects_details.php?id=235
GRANT_NUMBER: PDF/2016/000152
Source: Self-asserted source
Dr Mahendra Kumar Verma

Works (21)

Correction to: Nanotechnology based materials and inventions to fight against COVID-19: recent progress in the development of robust diagnostics, surveillance tools, therapeutics and vaccines

Health and Technology
2024-11 | Journal article
DOI: 10.1007/s12553-024-00891-2
Contributors: Shweta Kumar; Hema Singh; Mahendra Kumar Verma
Source: check_circle
Crossref

Nanotechnology based materials and inventions to fight against COVID-19: recent progress in the development of robust diagnostics, surveillance tools, therapeutics and vaccines

Health and Technology
2024-11 | Journal article
DOI: 10.1007/s12553-024-00880-5
Contributors: Shweta Kumar; Hema Singh; Mahendra Kumar Verma
Source: check_circle
Crossref

LRP-1 Mediated Endocytosis of EFE Across the Blood–Brain Barrier; Protein–Protein Interaction and Molecular Dynamics Analysis

International Journal of Peptide Research and Therapeutics
2021-03-18 | Journal article
DOI: 10.1007/s10989-020-10065-z
Contributors: M. K. Verma; S. Shakya
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genetic variation in the chemokine receptor 5 gene and course of HIV infection; review on genetics and immunological aspect

Genes and Diseases
2020 | Journal article
DOI: 10.1016/j.gendis.2020.04.007
EID:

2-s2.0-85084397050

Part of ISBN:

23523042
Contributors: Verma, M.K.; Shakya, S.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

MicroRNA hsa-miR-324-5p suppresses H5N1 virus replication by targeting the viral PB1 and host CUEDC2

Journal of Virology
2018 | Journal article
DOI: 10.1128/JVI.01057-18
EID:

2-s2.0-85053402537

Part of ISBN:

10985514 0022538X
Contributors: Kumar, A.; Kumar, A.; Ingle, H.; Kumar, S.; Mishra, R.; Verma, M.K.; Biswas, D.; Kumar, N.S.; Mishra, A.; Raut, A.A. et al.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Paradigm shift – Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discovery

Biotechnology Advances
2018 | Journal article
DOI: 10.1016/j.biotechadv.2018.02.014
EID:

2-s2.0-85043289083

Part of ISBN:

07349750
Contributors: Halade, G.V.; Black, L.M.; Verma, M.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Paradigm Shift - Metabolic Transformation of Docosahexaenoic and Eicosapentaenoic Acids to Bioactives Exemplify the Promise of Fatty Acid Drug Discovery

Biotechnology Advances
2018-02-16 | Journal article
Source: Self-asserted source
Dr Mahendra Kumar Verma

Broad substrate affinity and catalytic diversity of fibrinolytic enzyme from Pheretima posthumous—Purification and molecular characterization study

International Journal of Biological Macromolecules
2017 | Journal article
DOI: 10.1016/j.ijbiomac.2016.10.090
EID:

2-s2.0-85006066527

Part of ISBN:

18790003 01418130
Contributors: Verma, M.K.; Pulicherla, K.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Evaluation of the biological activity of the silver nanoparticles synthesized with the aqueous leaf extract of Rumex acetosa

Scientific Reprots
2017-09-24 | Journal article
DOI: doi:10.1038/s41598-017-11853-2
Source: Self-asserted source
Dr Mahendra Kumar Verma
grade
Preferred source (of 2)‎

An Investigation into phytochemical constituents, antioxidant, antibacterial and anti-cataract activity of Alternanthera sessilis, a predominant wild leafy vegetable of South India

Biocatalysis and Agricultural Biotechnology
2017-03-10 | Journal article
DOI: DOI: 10.1016/j.bcab.2017.03.008
Source: Self-asserted source
Dr Mahendra Kumar Verma
grade
Preferred source (of 2)‎

Broad substrate affinity and catalytic diversity of fibrinolytic enzyme from Pheretima posthumous—Purification and molecular characterization study

International Journal of Biological Macromolecules
2017-01-11 | Journal article
Source: Self-asserted source
Dr Mahendra Kumar Verma

Enzyme promiscuity in earthworm serine protease: Substrate versatility and therapeutic potential

Amino Acids
2016 | Journal article
DOI: 10.1007/s00726-015-2162-3
EID:

2-s2.0-84953212058

Part of ISBN:

14382199 09394451
Contributors: Verma, M.K.; Pulicherla, K.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Targeting Therapeutics Across the Blood Brain Barrier (BBB), Prerequisite Towards Thrombolytic Therapy for Cerebrovascular Disorders—an Overview and Advancements

2015 | Journal article
DOI: 10.1208/s12249-015-0287-z
EID:

2-s2.0-84921860429
Contributors: Pulicherla, K.K.; Verma, M.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Understanding the major risk factors in the beginning and the progression of rheumatoid arthritis: current scenario and future prospects.

2015-09 | Journal article
DOI: 10.1007/s00011-015-0843-8
PMID: 26149692
Contributors: Verma MK; Sobha K
Source: Self-asserted source
Dr Mahendra Kumar Verma via Europe PubMed Central
grade
Preferred source (of 2)‎

Statistical optimization of factors influencing the activity and the kinetics of partially purified lipase produced from Aspergillus japonicus (MTCC 1975) cultured in protein enriched medium

2014 | Journal article
EID:

2-s2.0-84924787411
Contributors: Sobha, K.; Lalitha, N.; Pavani, N.; Praharshini, R.; Pradeep, D.; Verma, M.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Antioxidant and anti-inflammatory properties of autolysed extract of the indian earthworm pheretima posthuma after preliminary purification - an in vitro study

2013 | Journal article
EID:

2-s2.0-84891121198
Contributors: Verma, M.K.; Sobha, K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Conventional thrombolytics need to refine at molecular level for safe and efficient management of cerebrovascular disorders- an overview

2013 | Journal article
EID:

2-s2.0-84875468819
Contributors: Verma, M.K.; Verma, Y.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

CT gene modulate differential expression of chitinase gene under variant habitats in Vibrio cholerae

2013 | Journal article
DOI: 10.1016/S2222-1808(13)60005-5
EID:

2-s2.0-84874351703
Contributors: Verma, Y.K.; Verma, M.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Evaluation of cytotoxic and anti-tumor activity of partially purified serine protease isolate from the Indian earthworm Pheretima posthuma

2013 | Journal article
DOI: 10.1016/S2221-1691(13)60175-6
EID:

2-s2.0-84884709392
Contributors: Verma, M.K.; Xavier, F.; Verma, Y.K.; Sobha, K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Earthworm- a potential source for stable and potent antimicrobial compounds- isolation and purification study

2012 | Journal article
EID:

2-s2.0-84870863122
Contributors: Verma, Y.K.; Verma, M.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Lumbrokinase - a potent and stable fibrin-specific plasminogen activator

2011 | Journal article
EID:

2-s2.0-79960730510
Contributors: Verma, M.K.; Pulicherla, K.K.
Source: Self-asserted source
Dr Mahendra Kumar Verma via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Genes and genomics. (1)
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