Personal information
Biography
I completed my PhD. and one year Post Doc. from prestigious Gyeongsang National University, South Korea in 2011. I have 16 year of teaching and research experience. My area of expertise are human genetics, includes gene structure and organization, gene expression, mutation detection and analysis, bioinformatics, gene therapy and gene editing, cellular and developmental neuroscience etc. My PhD work was based on the effect of ethanol on siRNA-Mediated GABAB1 receptor expression for downstream signaling pathways, apoptotic neurodegeneration, maternal epileptic seizure and role of GABABR1 receptor expression in early development of pre/postnatal rat brain.
Currently I am actively involved in Neurogenetic research program at CEGMR, working on rare, ulta rare and common neurologic disorders including Epilepsy, Autism, Mental retardation, Microcephaly and other neurodegenerative and neurodevelopmental disorders of Saudi Arabia. I am using microarray platform for array CGH, CNV/SNP analysis and Next generation technology for expression and whole exome/whole genome and Sanger sequencing analysis for identification of novel genes and mutations from rare genetic disorders in the Saudi Arabia. I have more than 16 years of research experience with more than 150 international peer reviewed article published reputed journals.
My aim of the research is to find novel genes and mutations specially the role of different KIFs genes in neurodegenerative disorders in the Saudi Arabia including Epilepsy, Autism, Alzheimer's intellectual disabilities and mental retardations. In addition, I use Knock-in/Knock-out animal models based on the identification of novel mutations/findings related to epileptic patients, rare genetics disorders for known as well as novel genetic aberrations to utilize them for testing novel therapeutic agents in a targeted therapeutic approach for rare, ultra rare genetic disorder, autism, epilepsy and microcephaly.