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Employment (4)

Genhouse Bio Co., Ltd.: Suzhou, CN

2018-11-01 to present | Drug Design Manger (Medicinal Chemistry)
Employment
Source: Self-asserted source
Faridoon

Shanghai Institute of Materia Medica: Shanghai, CN

2016-05-15 to present | Postdoc Fellow (Medicinal Chemistry)
Employment
Source: Self-asserted source
Faridoon

Rhodes University: Grahamstown, ZA

2014-01-03 to 2015-11-20 | Postdoc Fellow (Chemistry)
Employment
Source: Self-asserted source
Faridoon

Islamia College Peshawar: Peshawar, PK

2012-08-31 to 2013-08-31 | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Faridoon

Education and qualifications (1)

University of Peshawar: Peshawar, PK

2007-10-07 to 2012-05-26 | PhD (Institute of Chemical Science)
Education
Source: Self-asserted source
Faridoon

Works (22)

Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy

Journal of Medicinal Chemistry
2024-06-13 | Journal article
DOI: 10.1021/acs.jmedchem.4c00552
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Faridoon; Jiyue Zheng; Tao Zhang; Shuilong Tong; Tao Liu; Jiuen Cui; Haojie Xu; Di Hu; Ying Shen; Yajing Yin et al.
Source: Self-asserted source
Faridoon

An update on the discovery and development of reversible covalent inhibitors

Medicinal Chemistry Research
2023-06 | Journal article | Author
DOI: 10.1007/s00044-023-03065-3
Part of ISSN: 1054-2523
Part of ISSN: 1554-8120
Contributors: Faridoon; Raymond Ng; Guiping Zhang; Jie Li
Source: Self-asserted source
Faridoon

Medicinal chemistry insights into non-hydroxamate HDAC6 selective inhibitors

Medicinal Chemistry Research
2023-01 | Journal article
DOI: 10.1007/s00044-022-02987-8
Part of ISSN: 1054-2523
Part of ISSN: 1554-8120
Contributors: Faridoon; Yuqi Lavender Zha; Guiping Zhang; Jie Li
Source: Self-asserted source
Faridoon

Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery

Journal of Controlled Release
2022-02 | Journal article
DOI: 10.1016/j.jconrel.2021.11.045
Part of ISSN: 0168-3659
Contributors: Ziyue Xi; Ejaj Ahmad; Wei Zhang; Jingyi Li; Aohua Wang; Faridoon; Ning Wang; Chunliu Zhu; Wei Huang; Lu Xu et al.
Source: Self-asserted source
Faridoon

Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis

Bioorganic Chemistry
2020-01 | Journal article
DOI: 10.1016/j.bioorg.2019.103391
Part of ISSN: 0045-2068
Contributors: Ken Qin; Wei Shi; Lei Zhao; Mingjie Li; Yubo Tang; Faridoon; Bofeng Jiang; Feng Tang; Wei Huang
Source: Self-asserted source
Faridoon

Evaluation of novel<i>N</i>′-(3-hydroxybenzoyl)-2-oxo-2<i>H</i>-chromene-3-carbohydrazide derivatives as potential HIV-1 integrase inhibitors

MedChemComm
2019 | Journal article | Author
DOI: 10.1039/c8md00328a
Part of ISSN: 2040-2503
Part of ISSN: 2040-2511
Contributors: omobolanle jesumoroti; Faridoon; Dumisani Mnkandhla; Michelle Isaacs; Heinrich Hoppe; Rosalyn Klein
Source: Self-asserted source
Faridoon

New linker structures applied in glycosite-specific antibody drug conjugates

Organic Chemistry Frontiers
2019 | Journal article
DOI: 10.1039/c9qo00646j
Part of ISSN: 2052-4129
Contributors: Faridoon Faridoon; Wei Shi; Ken Qin; Yubo Tang; Mingjie Li; Dongliang Guan; Xiaobo Tian; Bofeng Jiang; Jinhua Dong; Feng Tang et al.
Source: Self-asserted source
Faridoon

Design and Synthesis of Pyrophosphate‐Targeting Vancomycin Derivatives for Combating Vancomycin‐Resistant <i>Enterococci</i>

ChemMedChem
2018-08-20 | Journal article
DOI: 10.1002/cmdc.201800252
Part of ISSN: 1860-7179
Part of ISSN: 1860-7187
Contributors: Given Names Deactivated Family Name Deactivated; Feifei Chen; Faridoon; Junjie Liu; Jian Li; Lefu Lan; Wei Huang
Source: Self-asserted source
Faridoon

On-resin peptide ligation via C-terminus benzyl ester

Chinese Chemical Letters
2018-07 | Journal article
DOI: 10.1016/j.cclet.2018.03.021
Part of ISSN: 1001-8417
Contributors: Bin Zhou; Faridoon; Xiaobo Tian; Jian Li; Dongliang Guan; Xing Zheng; Yu Guo; Wei Huang
Source: Self-asserted source
Faridoon

Synthesis and evaluation of substituted 4-arylimino-3-hydroxybutanoic acids as potential HIV-1 integrase inhibitors

Bioorganic &amp; Medicinal Chemistry Letters
2018-04 | Journal article
DOI: 10.1016/j.bmcl.2018.02.020
Part of ISSN: 0960-894X
Contributors: Faridoon; Dumisani Mnkandhla; Michelle Isaacs; Heinrich C. Hoppe; Perry T. Kaye
Source: Self-asserted source
Faridoon

Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant <i>Staphylococcus aureus</i> and Vancomycin-Resistant <i>Enterococci</i>

Journal of Medicinal Chemistry
2018-01-11 | Journal article
DOI: 10.1021/acs.jmedchem.7b01345
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Dongliang Guan; Feifei Chen; Lun Xiong; Feng Tang; Faridoon; Yunguang Qiu; Naixia Zhang; Likun Gong; Jian Li; Lefu Lan et al.
Source: Self-asserted source
Faridoon

Synthesis and antimalarial activity of N-benzylated (N-arylcarbamoyl)alkylphosphonic acid derivatives

Bioorganic &amp; Medicinal Chemistry
2016-12 | Journal article
DOI: 10.1016/j.bmc.2016.04.021
Part of ISSN: 0968-0896
Contributors: Christiana M. Adeyemi; Faridoon; Michelle Isaacs; Dumisani Mnkandhla; Heinrich C. Hoppe; Rui W.M. Krause; Perry T. Kaye
Source: Self-asserted source
Faridoon

Synthesis and evaluation of substituted 4-(N-benzylamino)cinnamate esters as potential anti-cancer agents and HIV-1 integrase inhibitors

Bioorganic &amp; Medicinal Chemistry Letters
2016-08 | Journal article
DOI: 10.1016/j.bmcl.2016.05.023
Part of ISSN: 0960-894X
Contributors: Faridoon; Adrienne L Edkins; Michelle Isaacs; Dumisani Mnkandhla; Heinrich C. Hoppe; Perry T. Kaye
Source: Self-asserted source
Faridoon

Application of Baylis-Hillman methodology in the direct construction of chromone derivatives

Tetrahedron
2016-01 | Journal article
DOI: 10.1016/j.tet.2015.11.039
Part of ISSN: 0040-4020
Contributors: Faridoon; Temitope O. Olomola; Rosalyn Klein; Perry T. Kaye
Source: Self-asserted source
Faridoon

Strong base- or acid-mediated chemoselectivity shifts in the synthesis of 2H-chromene or coumarin derivatives from common Baylis-Hillman adducts

Tetrahedron
2015-07 | Journal article
DOI: 10.1016/j.tet.2015.04.104
Part of ISSN: 0040-4020
Contributors: Faridoon; Temitope O. Olomola; Matshawandile Tukulula; Rosalyn. Klein; Perry T. Kaye
Source: Self-asserted source
Faridoon

Synthesis, characterization, antioxidant and selective xanthine oxidase inhibitory studies of transition metal complexes of novel amino acid bearing Schiff base ligand

Inorganica Chimica Acta
2015-03 | Journal article
DOI: 10.1016/j.ica.2015.01.021
Part of ISSN: 0020-1693
Contributors: Ikram; Sadia Rehman; Ajmal Khan; Robert J. Baker; Thomas S. Hofer; Fazle Subhan; Mughal Qayum; Faridoon; Carola Schulzke
Source: Self-asserted source
Faridoon

An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases

Scientia Pharmaceutica
2013 | Journal article
DOI: 10.3797/scipharm.1302-08
Part of ISSN: 0036-8709
Part of ISSN: 2218-0532
Contributors: Faridoon
Source: Self-asserted source
Faridoon

Bioisosteric synthesis of nitrogen containing derivatives of salicyl alcohol, their in vivo pharmacological studies with molecular modeling

Medicinal Chemistry Research
2013-10 | Journal article
DOI: 10.1007/s00044-013-0473-z
Part of ISSN: 1054-2523
Part of ISSN: 1554-8120
Contributors: Nasir Ullah; Nazar Ul Islam; Gowhar Ali; Fazal Subhan; Faridoon; Ikhtiar Khan
Source: Self-asserted source
Faridoon

Urease and α-chymotrypsin inhibitory activities of transition metal complexes of new Schiff base ligand: Kinetic and thermodynamic studies of the synthesized complexes using TG–DTA pyrolysis

Thermochimica Acta
2013-06 | Journal article
DOI: 10.1016/j.tca.2013.03.026
Part of ISSN: 0040-6031
Contributors: Muhammad Ikram; Sadia Rehman; Muhammad Ali; Faridoon; Carola Schulzke; Robert J. Baker; Alexander J. Blake; Khan Malook; Henry Wong; Saeed-Ur-Rehman
Source: Self-asserted source
Faridoon

Synthesis and distinct urease enzyme inhibitory activities of metal complexes of Schiff-base ligands: Kinetic and thermodynamic parameters evaluation from TG-DTA analysis

Thermochimica Acta
2013-03 | Journal article
DOI: 10.1016/j.tca.2012.12.023
Part of ISSN: 0040-6031
Contributors: Muhammad Ikram; Sadia Rehman; Faridoon; Robert J. Baker; Hanif Ur Rehman; Ajmal Khan; Muhammad Iqbal Choudhary; Saeed-Ur -Rehman
Source: Self-asserted source
Faridoon

Penicillin inhibitors of purple acid phosphatase

Bioorganic &amp; Medicinal Chemistry Letters
2012-04 | Journal article
DOI: 10.1016/j.bmcl.2012.01.123
Part of ISSN: 0960-894X
Contributors: Faridoon; Waleed M. Hussein; Nazar Ul Islam; Luke W. Guddat; Gerhard Schenk; Ross P. McGeary
Source: Self-asserted source
Faridoon

3-Mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors

Bioorganic &amp; Medicinal Chemistry Letters
2012-01 | Journal article
DOI: 10.1016/j.bmcl.2011.10.116
Part of ISSN: 0960-894X
Contributors: Faridoon; Waleed M. Hussein; Peter Vella; Nazar Ul Islam; David L. Ollis; Gerhard Schenk; Ross P. McGeary
Source: Self-asserted source
Faridoon
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