Personal information

United Kingdom

Activities

Employment (2)

Diamond Light Source: Didcot, GB

2017-04-03 to present | Rutherford International Fellow (Science/B23)
Employment
Source: Self-asserted source
Ashley Hughes

University of Gothenburg: Gothenburg, SE

2014-10-01 to 2017-03-31 | Post-Doc (Department of Chemistry and Molecular Biology)
Employment
Source: Self-asserted source
Ashley Hughes

Education and qualifications (2)

University of Liverpool: Liverpool, Liverpool, GB

2010-10-01 to 2014-09-31 | PhD (Institute of Integrative Biology)
Education
Source: Self-asserted source
Ashley Hughes

University of Liverpool: Liverpool, Liverpool, GB

2010-06-31 | Biochemistry Bsc (Hons) (IIB)
Education
Source: Self-asserted source
Ashley Hughes

Works (14)

Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase.

Nature Communications
2017-08 | Journal article
Source: Self-asserted source
Ashley Hughes via Europe PubMed Central

Time-Resolved X-Ray Solution Scattering Reveals the Structural Photoactivation of a Light-Oxygen-Voltage Photoreceptor.

2017-06 | Journal article
Contributors: Berntsson O; Diensthuber RP; Panman MR; Björling A; Hughes AJ; Henry L; Niebling S; Newby G; Liebi M; Menzel A et al.
Source: Self-asserted source
Ashley Hughes via Europe PubMed Central

Assessing the Ability of Spectroscopic Methods to Determine the Difference in the Folding Propensities of Highly Similar β-Hairpins.

2017-02 | Journal article
Contributors: Andersson H; Danelius E; Jarvoll P; Niebling S; Hughes AJ; Westenhoff S; Brath U; Erdélyi M
Source: Self-asserted source
Ashley Hughes via Europe PubMed Central

Investigating the relationship between temperature, conformation and calcium binding in heparin model oligosaccharides.

2017-01 | Journal article
Contributors: Hughes A; Meneghetti M; Huang TY; Hung SC; Elli S; Guerrini M; Rudd T; Lima M; Yates E
Source: Self-asserted source
Ashley Hughes via Europe PubMed Central

Structural photoactivation of a full-length bacterial phytochrome.

2016-08 | Journal article
Contributors: Björling A; Berntsson O; Lehtivuori H; Takala H; Hughes AJ; Panman M; Hoernke M; Niebling S; Henry L; Henning R et al.
Source: Self-asserted source
Ashley Hughes via Europe PubMed Central

Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis

Oncotarget
2015 | Journal article
EID:

2-s2.0-84943426117

Contributors: Duckworth, C.A.; Guimond, S.E.; Sindrewicz, P.; Hughes, A.J.; French, N.S.; Lian, L.-Y.; Yates, E.A.; Mark Pritchard, D.; Rhodes, J.M.; Turnbull, J.E. et al.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism

Analytical Methods
2015 | Journal article
EID:

2-s2.0-84923998450

Contributors: Hughes, A.J.; Rudd, T.R.; Wright, G.S.A.; Fernig, D.G.; Siligardi, G.; Yates, E.A.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Heparan sulfate and heparin interactions with proteins

Journal of the Royal Society Interface
2015 | Journal article
EID:

2-s2.0-84942019114

Contributors: Meneghetti, M.C.Z.; Hughes, A.J.; Rudd, T.R.; Nader, H.B.; Powell, A.K.; Yates, E.A.; Lima, M.A.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Heparin derivatives for the targeting of multiple activities in the inflammatory response

Carbohydrate Polymers
2015 | Journal article
EID:

2-s2.0-84908284168

Contributors: Veraldi, N.; Hughes, A.J.; Rudd, T.R.; Thomas, H.B.; Edwards, S.W.; Hadfield, L.; Skidmore, M.A.; Siligardi, G.; Cosentino, C.; Shute, J.K. et al.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential

Carbohydrate Polymers
2014 | Journal article
EID:

2-s2.0-84883716644

Contributors: Brito, A.S.; Cavalcante, R.S.; Palhares, L.C.G.F.; Hughes, A.J.; Andrade, G.P.V.; Yates, E.A.; Nader, H.B.; Lima, M.A.; Chavante, S.F.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: Evidence for the expansion of the core FGFR signalling network

FEBS Journal
2013 | Journal article
EID:

2-s2.0-84877696797

Contributors: Xu, R.; Rudd, T.R.; Hughes, A.J.; Siligardi, G.; Fernig, D.G.; Yates, E.A.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity

MedChemComm
2013 | Journal article
EID:

2-s2.0-84877253457

Contributors: Lima, M.A.; Hughes, A.J.; Veraldi, N.; Rudd, T.R.; Hussain, R.; Brito, A.S.; Chavante, S.F.; Tersariol, I.I.; Siligardi, G.; Nader, H.B. et al.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

A zinc complex of heparan sulfate destabilises lysozyme and alters its conformation

Biochemical and Biophysical Research Communications
2012 | Journal article
EID:

2-s2.0-84865962126

Contributors: Hughes, A.J.; Hussain, R.; Cosentino, C.; Guerrini, M.; Siligardi, G.; Yates, E.A.; Rudd, T.R.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier

Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment

Brazilian Journal of Medical and Biological Research
2012 | Journal article
EID:

2-s2.0-84861121953

Contributors: Rudd, T.R.; Hughes, A.; Holman, J.; De Oliveira Ferreira, E.; Cavalcante Pilotto Domingues, R.M.; Yates, E.A.
Source: Self-asserted source
Ashley Hughes via Scopus - Elsevier