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Central University of Punjab: Bathinda, Punjab, IN

2015-07-15 to present | Assistant Professor (Department of Biochemistry)
Employment
Source: Self-asserted source
shashank kumar

Works (50 of 86)

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Optimizing selective estrogen receptor degraders for anticancer drug development

Future Medicinal Chemistry
2025-03-19 | Journal article
Contributors: Neha Bhatia; Shashank Kumar; Lajya Devi Goyal; Suresh Thareja
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Designing of neoepitopes based vaccine against breast cancer using integrated immuno and bioinformatics approach

Journal of Biomolecular Structure and Dynamics
2024-11 | Journal article
Contributors: Mohd Shuaib; Atul Kumar Singh; Sanjay Gupta; Abdullah F. Alasmari; Flaeh Alqahtani; Shashank Kumar
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Implications of vitamin D deficiency in systemic inflammation and cardiovascular health

Critical Reviews in Food Science and Nutrition
2024-11-05 | Journal article
Contributors: Sanjay Kumar Dey; Shashank Kumar; Diksha Rani; Shashank Kumar Maurya; Pratibha Banerjee; Madhur Verma; Sabyasachi Senapati
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Ancistrobrevinium A, the first N -methylated, cationic naphthylisoquinoline alkaloid, from the tropical liana Ancistrocladus abbreviatus (Ancistrocladaceae)

Natural Product Research
2024-08-02 | Journal article
Contributors: Nasir Tajuddeen; Shaimaa Fayez; Prem Prakash Kushwaha; Doris Feineis; Laurent Aké Assi; Shashank Kumar; Gerhard Bringmann
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Role of ONECUT family transcription factors in cancer and other diseases

Experimental Cell Research
2024-05 | Journal article
Contributors: Kumari Sunita Prajapati; Sanjay Gupta; Smriti Chaudhri; Shashank Kumar
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Kurarinone targets JAK2‐STAT3 signaling in colon cancer‐stem‐like cells

Cell Biochemistry and Function
2024-03 | Journal article
Contributors: Kumari Sunita Prajapati; Shashank Kumar
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Synthesis of novel ( R )-carvone-tagged thiazolidinone as anticancer leads: characterization, in vitro antiproliferative evaluation and in silico studies

Journal of Biomolecular Structure and Dynamics
2024-03-25 | Journal article
Contributors: Yassine Riadi; Obaid Afzal; Shashank Kumar; Venkatramanan Varadharajan; Mohammed H. Geesi
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Exploring the Potential of Essential Oil from Plectranthus amboinicus Leaves against Breast Cancer: In vitro and In silico Analysis

Medical Oncology
2024-02-24 | Journal article
Contributors: Khushi Gupta; Pranay Gautre; Avadh Biharee; Yogesh Singh; Umesh Kumar Patil; Shashank Kumar; Suresh Thareja
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Discovery of anticancer compound possessing potential to bind γ-secretase catalytic subunit and inhibit notch promoter activity

Journal of Biomolecular Structure and Dynamics
2024-02-12 | Journal article
Contributors: Atul Kumar Singh; Kumari Sunita Prajapati; Shashank Kumar
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Piper chaba, an Indian spice plant extract, inhibits cell cycle G1/S phase transition and induces intrinsic apoptotic pathway in luminal breast cancer cells

Cell Biochemistry and Function
2023-12 | Journal article
Contributors: Kumari Sunita Prajapati; Shashank Kumar
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Specific Genetic Polymorphisms Contributing in Differential Binding of Gliadin Peptides to HLA-DQ and TCR to Elicit Immunogenicity in Celiac Disease

Biochemical Genetics
2023-12 | Journal article
Contributors: Pratibha Banerjee; Ramprasad Chaudhary; Atul Kumar Singh; Pratima Parulekar; Shashank Kumar; Sabyasachi Senapati
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Flavonoids as emerging notch signaling pathway modulators in cancer

Journal of Asian Natural Products Research
2023-12-02 | Journal article
Contributors: Atul Kumar Singh; Shashank Kumar
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Bioinformatics insights into CENP‐T and CENP‐W protein‐protein interaction disruptive amino acid substitution in the CENP‐T‐W complex

Journal of Cellular Biochemistry
2023-11 | Journal article
Contributors: Suryakanta Mohanty; Rajendra Bhadane; Shashank Kumar
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Hesperidin potentially interacts with the catalytic site of gamma-secretase and modifies notch sensitive genes and cancer stemness marker expression in colon cancer cells and colonosphere

Journal of Biomolecular Structure and Dynamics
2023-11-22 | Journal article
Contributors: Atul Kumar Singh; Kumari Sunita Prajapati; Shashank Kumar
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Novel Eubacterium rectale inhibitor from Coriandrum sativum L. for possible prevention of colorectal cancer: a computational approach

Journal of Biomolecular Structure and Dynamics
2023-11-22 | Journal article
Contributors: Khalil El Khatabi; Shashank Kumar; Reda El-Mernissi; Atul Kumar Singh; Mohammed Aziz Ajana; Tahar Lakhlifi; Mohammed Bouachrine
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Loss of miR‐6844 alters stemness/self‐renewal and cancer hallmark(s) markers through CD44‐JAK2‐STAT3 signaling axis in breast cancer stem‐like cells

Journal of Cellular Biochemistry
2023-08 | Journal article
Contributors: Kumari Sunita Prajapati; Shashank Kumar
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GNL3 and PA2G4 as Prognostic Biomarkers in Prostate Cancer

Cancers
2023-05-11 | Journal article
Contributors: Shashank Kumar; Mohd Shuaib; Abdullah F. AlAsmari; Faleh Alqahtani; Sanjay Gupta
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Multifaceted 3D-QSAR analysis for the identification of pharmacophoric features of biphenyl analogues as aromatase inhibitors

Journal of Biomolecular Structure and Dynamics
2023-03-04 | Journal article
Contributors: Laxmi Banjare; Yogesh Singh; Sant Kumar Verma; Atul Kumar Singh; Pradeep Kumar; Shashank Kumar; Akhlesh Kumar Jain; Suresh Thareja
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Induced expression of miR‐1250‐5p exerts tumor suppressive role in triple‐negative breast cancer cells

Journal of Cellular Biochemistry
2023-02 | Journal article
Contributors: Mohd Shuaib; Shashank Kumar
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In silico identification of potential γ-secretase inhibitor of marine-algal origin: an anticancer intervention

Molecular Simulation
2023-02-11 | Journal article
Contributors: Atul Kumar Singh; Princy Choudhary; Sangeeta Singh; Shashank Kumar
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Potential Molecular Targeted Therapy for Unresectable Hepatocellular Carcinoma

Current Oncology
2023-01-18 | Journal article
Contributors: Shashank Kumar; Abhay Kumar Pandey
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Repurposing FDA-approved anti-diabetic drug to target H. pylori peptidyl deformylase using computer-based drug discovery approach

Molecular Simulation
2023-01-02 | Journal article
Contributors: Atul Kumar Singh; Santosh Maurya; Shashank Kumar
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Natural Steroidal Lactone Induces G1/S Phase Cell Cycle Arrest and Intrinsic Apoptotic Pathway by Up-Regulating Tumor Suppressive miRNA in Triple-Negative Breast Cancer Cells

Metabolites
2022-12-24 | Journal article
Contributors: Mohd Shuaib; Kumari Sunita Prajapati; Sanjay Gupta; Shashank Kumar
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Targeting mitochondrial bioenergetics as a promising therapeutic strategy in metabolic and neurodegenerative diseases

Biomedical Journal
2022-10 | Journal article
Contributors: Gurjit Kaur Bhatti; Anshika Gupta; Paras Pahwa; Naina Khullar; Satwinder Singh; Umashanker Navik; Shashank Kumar; Sarabjit Singh Mastana; Arubala P. Reddy; P. Hemachandra Reddy et al.
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Withaferin A mediated changes of miRNA expression in breast cancer‐derived mammospheres

Molecular Carcinogenesis
2022-09 | Journal article
Contributors: Kumari Sunita Prajapati; Mohd. Shuaib; Sanjay Gupta; Shashank Kumar
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Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres

Metabolites
2022-09-29 | Journal article
Contributors: Atul Kumar Singh; Mohd Shuaib; Kumari Sunita Prajapati; Shashank Kumar
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The Multifaceted Role of Signal Peptide-CUB-EGF Domain-Containing Protein (SCUBE) in Cancer

International Journal of Molecular Sciences
2022-09-12 | Journal article
Contributors: Shashank Kumar; Kumari Sunita Prajapati; Sanjay Gupta
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Withania somnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential

Vegetos
2022-06-15 | Journal article
Contributors: Kumari Sunita Prajapati; Atul Kumar Singh; Prem Prakash Kushwaha; Mohd Shuaib; Santosh Kumar Maurya; Sanjay Gupta; Sabyasachi Senapati; Surya Pratap Singh; Mohammad Waseem; Shashank Kumar
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Targeting Breast Cancer-Derived Stem Cells by Dietary Phytochemicals: A Strategy for Cancer Prevention and Treatment

Cancers
2022-06-10 | Journal article
Contributors: Kumari Sunita Prajapati; Sanjay Gupta; Shashank Kumar
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A candidate triple-negative breast cancer vaccine design by targeting clinically relevant cell surface markers: an integrated immuno and bio-informatics approach

3 Biotech
2022-03 | Journal article
Contributors: Shashank Kumar; Mohd Shuaib; Kumari Sunita Prajapati; Atul Kumar Singh; Princy Choudhary; Sangeeta Singh; Sanjay Gupta
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Drug Resistance Mechanism of M46I-Mutation-Induced Saquinavir Resistance in HIV-1 Protease Using Molecular Dynamics Simulation and Binding Energy Calculation

Viruses
2022-03-28 | Journal article
Contributors: Nilottam Rana; Atul Kumar Singh; Mohd Shuaib; Sanjay Gupta; Mahmoud M. Habiballah; Mustfa F. Alkhanani; Shafiul Haque; Mohd Salim Reshi; Shashank Kumar
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Identification of cancer stemness related miRNA(s) using integrated bioinformatics analysis and in vitro validation

3 Biotech
2021-10 | Journal article
Contributors: Kumari Sunita Prajapati; Mohd Shuaib; Prem Prakash Kushwaha; Atul Kumar Singh; Shsahank Kumar
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Phytochemicals present in Indian ginseng possess potential to inhibit SARS-CoV-2 virulence: A molecular docking and MD simulation study

Microbial Pathogenesis
2021-08 | Journal article
Contributors: Prem Prakash Kushwaha; Atul Kumar Singh; Kumari Sunita Prajapati; Mohd Shuaib; Sanjay Gupta; Shashank Kumar
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Identification of potential natural inhibitors of SARS-CoV2 main protease by molecular docking and simulation studies

Journal of Biomolecular Structure and Dynamics
2021-08-13 | Journal article
Contributors: Sanjay Gupta; Atul Kumar Singh; Prem Prakash Kushwaha; Kumari Sunita Prajapati; Mohd Shuaib; Sabyasachi Senapati; Shashank Kumar
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Integrated 3D-QSAR, molecular docking, and molecular dynamics simulation studies on 1,2,3-triazole based derivatives for designing new acetylcholinesterase inhibitors

TURKISH JOURNAL OF CHEMISTRY
2021-06-30 | Journal article
Contributors: Khalil EL KHATABI; Ilham AANOUZ; Reda El-MERNISSI; Atul Kumar SINGH; Mohammed Aziz AJANA; Tahar LAKHLIFI; Shashank KUMAR; Mohammed BOUACHRINE
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Identification of FDA approved drugs and nucleoside analogues as potential SARS-CoV-2 A1pp domain inhibitor: An in silico study

Computers in Biology and Medicine
2021-03 | Journal article
Contributors: Atul Kumar Singh; Prem Prakash Kushwaha; Kumari Sunita Prajapati; Mohd Shuaib; Sanjay Gupta; Shashank Kumar
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Bioactive lead compounds and targets for the development of antimalarial drugs

Phytochemicals as Lead Compounds for New Drug Discovery
2020 | Other
Contributors: Prem Prakash Kushwaha; Pothabathula Seshu Vardhan; Priyanka Kumari; Andrew G. Mtewa; Shashank Kumar
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Functional lead compounds and targets for the development of drugs for the treatment of male infertility

Phytochemicals as Lead Compounds for New Drug Discovery
2020 | Other
Contributors: Manisha Pathak; Shrikant Sharma; Prem Prakash Kushwaha; Shashank Kumar
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Prenylated flavonoids as a promising drug discovery candidate

Phytochemicals as Lead Compounds for New Drug Discovery
2020 | Other
Contributors: Prem Prakash Kushwaha; Sunita Kumari Prajapati; Seshu Vardhan Pothabathula; Atul Kumar Singh; Mohd Shuaib; Karnika Joshi; Shashank Kumar
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3-O-(E)-p-Coumaroyl betulinic acid possess anticancer activity and inhibit Notch signaling pathway in breast cancer cells and mammosphere

Chemico-Biological Interactions
2020-09 | Journal article
Part of ISSN: 0009-2797
Contributors: Prem Prakash Kushwaha; Atul Kumar Singh; Mohd Shuaib; Kumari Sunita Prajapati; Pothabathula Seshu Vardhan; Sanjay Gupta; Shashank Kumar
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Emerging role of ZBTB7A as an oncogenic driver and transcriptional repressor

Cancer Letters
2020-07 | Journal article
Part of ISSN: 0304-3835
Contributors: Sanjay Gupta; Atul Kumar Singh; Kumari Sunita Prajapati; Prem Prakash Kushwaha; Mohd Shuaib; Shashank Kumar
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MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer

Antioxidants & Redox Signaling
2020-01-01 | Journal article
Part of ISSN: 1523-0864
Contributors: Prem Prakash Kushwaha; Sanjay Gupta; Atul Kumar Singh; Kumari Sunita Prajapati; Mohd Shuaib; Shashank Kumar
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Emerging targets in cancer drug resistance

Cancer Drug Resistance
2019 | Journal article
Part of ISSN: 2578-532X
Contributors: Shashank Kumar; Prem Prakash Kushwaha; Sanjay Gupta
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Bulbine frutescens phytochemical inhibits notch signaling pathway and induces apoptosis in triple negative and luminal breast cancer cells

Life Sciences
2019-10 | Journal article
Part of ISSN: 0024-3205
Contributors: Prem Prakash Kushwaha; Pothabathula Sheshu Vardhan; Petrina Kapewangolo; Mohammad Shuaib; Sunita Kumari Prajapati; Atul Kumar Singh; Shashank Kumar
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Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis

Frontiers in Oncology
2019-09-04 | Journal article
Part of ISSN: 2234-943X
Contributors: Prem Prakash Kushwaha; Sanjay Gupta; Atul Kumar Singh; Shashank Kumar
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Anticancer and Neuroprotective Activity of Chrysin: Recent Advancement

Phytochemistry: An in-silico and in-vitro Update
2019-06 | Other
Contributors: Pushpendra Singh; Ravi S. Singh; Prem P. Kushwaha; Shashank Kumar
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Association Between Nuclear Receptor Coactivator 1 and Stem Cell Signaling Pathway and Identification of Natural NCOA1 Inhibitors: An in-silico Study

Phytochemistry: An in-silico and in-vitro Update
2019-06 | Other
Contributors: Pushpendra Singh; Prem P. Kushwaha; Atul K. Singh; Shashank Kumar
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In-silico Methods of Drug Design: Molecular Simulations and Free Energy Calculations

Phytochemistry: An in-silico and in-vitro Update
2019-06 | Other
Contributors: Fortunatus Chidolue Ezebuo; Prem P. Kushwaha; Atul K. Singh; Shashank Kumar; Pushpendra Singh
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Parthenin and Its Similar Structure as Potential Lead Inhibitors of Plasmodium vivax and Plasmodium falciparum Lactate Dehydrogenase

Phytochemistry: An in-silico and in-vitro Update
2019-06 | Other
Contributors: Pushpendra Singh; Prem P. Kushwaha; Shashank Kumar
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Phytochemicals, Cancer and miRNAs: An in-silico Approach

Phytochemistry: An in-silico and in-vitro Update
2019-06 | Other
Contributors: Neha Kashyap; Prem P. Kushwaha; Atul K. Singh; Santosh Maurya; Ashish K. Sahoo; Shashank Kumar
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Peer review (18 reviews for 11 publications/grants)

Review activity for 3 biotech. (2)
Review activity for Biochemical genetics. (1)
Review activity for Biomedical journal. (1)
Review activity for Computers in biology and medicine. (1)
Review activity for Ecotoxicology and environmental safety. (1)
Review activity for Journal of cell communication and signaling. (1)
Review activity for Journal of herbal medicine. (1)
Review activity for Molecular biology reports. (1)
Review activity for National Academy Science letters. (2)
Review activity for Vegetos. (6)
Review activity for World journal of surgical oncology (1)