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Employment (4)

Omico: Sydney, NSW, AU

2019 to present | Head of Cohorts
Employment
Source: Self-asserted source
Mandy Ballinger

Garvan Institute of Medical Research: Sydney, NSW, AU

2016 to present | Group Leader - Genetic Cancer Risk (Cancer Division)
Employment
Source: Self-asserted source
Mandy Ballinger

International Sarcoma Kindred Study: Sydney, NSW, AU

2008 to present | Global Co-ordinator
Employment
Source: Self-asserted source
Mandy Ballinger

Peter MacCallum Cancer Centre: Melbourne, Victoria, AU

2008 to 2015 | Post-doctoral Research Fellow
Employment
Source: Self-asserted source
Mandy Ballinger

Education and qualifications (4)

University of Sydney: Sydney, NSW, AU

2016 to 2017 | Master of Genetic Counselling
Education
Source: Self-asserted source
Mandy Ballinger

Monash University: Melbourne, Victoria, AU

2006 | PhD, General Medicine
Education
Source: Self-asserted source
Mandy Ballinger

Monash University: Melbourne, Victoria, AU

2002 | Bachelor of Science, First class Honours (Biochemistry)
Education
Source: Self-asserted source
Mandy Ballinger

Monash University: Melbourne, Victoria, AU

2001 | Bachelor of Applied Science
Education
Source: Self-asserted source
Mandy Ballinger

Works (50 of 59)

Items per page:
Page 1 of 2

POT1 clinical risk management is an open question

European Journal of Human Genetics
2025-01 | Journal article
DOI: 10.1038/s41431-024-01676-x
Contributors: Mandy L. Ballinger; David M. Thomas
Source: check_circle
Crossref

Increased frequency of CHEK2 germline pathogenic variants among individuals with dermatofibrosarcoma protuberans

Genetics in Medicine Open
2024 | Journal article
DOI: 10.1016/j.gimo.2024.101895
Contributors: Michael R. Sargen; Jung Kim; Jeremy S. Haley; Hayley P. Barker; Piyushkumar A. Mundra; Mandy L. Ballinger; David M. Thomas; David J. Carey; Alisa M. Goldstein; Douglas R. Stewart
Source: check_circle
Crossref

From ownership to custodianship of tumor biopsy tissue in genomic testing: a mixed methods study of patient views

The Oncologist
2024-09-06 | Journal article
DOI: 10.1093/oncolo/oyae074
Contributors: Megan C Best; Phyllis Butow; Jacqueline Savard; Ainsley J Newson; Rachel Campbell; Sabina Vatter; Christine E Napier; Nicci Bartley; Katherine Tucker; Mandy L Ballinger et al.
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Crossref

ASPiRATION: Australian Observational Cohort Study of Comprehensive Genomic Profiling in Metastatic Lung Cancer Tissue

Future Oncology
2024-03 | Journal article
DOI: 10.2217/fon-2023-0366
Contributors: Antony J Mersiades; J Solomon Benjamin; M Thomas David; Chee K Lee; Michelle M Cummins; Lucille Sebastian; Mandy L Ballinger; Emily Collignon; Olivia MH Turnbull; Sonia Yip et al.
Source: check_circle
Crossref

Heritable defects in telomere and mitotic function selectively predispose to sarcomas

Science
2023-01-20 | Journal article
DOI: 10.1126/science.abj4784
Contributors: Mandy L. Ballinger; Swetansu Pattnaik; Piyushkumar A. Mundra; Milita Zaheed; Emma Rath; Peter Priestley; Jonathan Baber; Isabelle Ray-Coquard; Nicholas Isambert; Sylvain Causeret et al.
Source: check_circle
Crossref

Return of comprehensive tumour genomic profiling results to advanced cancer patients: a qualitative study

Supportive Care in Cancer
2022-10 | Journal article
DOI: 10.1007/s00520-022-07272-3
Contributors: Megan C. Best; Nicci Bartley; Christine E. Napier; Alana Fisher; Mandy L. Ballinger; David M. Thomas; David Goldstein; Katherine Tucker; Barbara B. Biesecker; Phyllis Butow
Source: check_circle
Crossref

Validation of the multidimensional impact of Cancer Risk Assessment Questionnaire to assess impact of waiting for genome sequencing results

Psycho-Oncology
2022-07 | Journal article
DOI: 10.1002/pon.5908
Contributors: Megan Best; Christine Napier; Timothy Schlub; Nicci Bartley; Barbara Biesecker; Mandy Ballinger; Phyllis Butow
Source: check_circle
Crossref

Psychological outcomes in advanced cancer patients after receiving genomic tumor profiling results.

Health Psychology
2022-06 | Journal article
DOI: 10.1037/hea0001181
Contributors: Sabina Vatter; Timothy E. Schlub; Christine E. Napier; Megan C. Best; Nicci Bartley; Ilona Juraskova; Bettina Meiser; Mandy L. Ballinger; Barbara B. Biesecker; David Goldstein et al.
Source: check_circle
Crossref

Fear of cancer recurrence in patients undergoing germline genome sequencing

Supportive Care in Cancer
2021-12 | Journal article
DOI: 10.1007/s00520-021-06311-9
Contributors: Nicci Bartley; Grace Davies; Phyllis Butow; Christine E. Napier; Tim Schlub; Mandy L. Ballinger; David M. Thomas; Ilona Juraskova; Bettina Meiser; Megan C. Best
Source: check_circle
Crossref

Streamlined use of protein structures in variant analysis

2021-09-11 | Preprint
DOI: 10.1101/2021.09.10.459756
Contributors: Sandeep Kaur; Neblina Sikta; Andrea Schafferhans; Nicola Bordin; Mark J. Cowley; David M. Thomas; Mandy L. Ballinger; Seán I. O’Donoghue
Source: check_circle
Crossref

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology

2020-12-22 | Preprint
DOI: 10.1101/2020.12.18.20248521
Contributors: Frank P. Lin; Subotheni Thavaneswaran; John P. Grady; Mandy Ballinger; Maya Kansara; Samantha R. Oakes; Jayesh Desai; Chee Khoon Lee; John Simes; David M. Thomas
Source: check_circle
Crossref

Advanced cancer patient preferences for receiving molecular profiling results

Psycho-Oncology
2020-10 | Journal article
DOI: 10.1002/pon.5446
Contributors: Megan Best; Phyllis Butow; Chris Jacobs; Ilona Juraskova; Jacqueline Savard; Bettina Meiser; David Goldstein; Mandy Ballinger; Nicci Bartley; Christine Napier et al.
Source: check_circle
Crossref

Advanced Cancer Patient Knowledge of and Attitudes towards Tumor Molecular Profiling

Translational Oncology
2020-09 | Journal article
DOI: 10.1016/j.tranon.2020.100799
Contributors: Grace Davies; Phyllis Butow; Christine E. Napier; Nicci Bartley; Ilona Juraskova; Bettina Meiser; Mandy L. Ballinger; David M. Thomas; Timothy E. Schlub; Megan C. Best
Source: check_circle
Crossref

Who should access germline genome sequencing? A mixed methods study of patient views

Clinical Genetics
2020-02 | Journal article
DOI: 10.1111/cge.13664
Contributors: Megan C. Best; Phyllis Butow; Chris Jacobs; Jacqueline Savard; Barbara Biesecker; Mandy L. Ballinger; Nicci Bartley; Grace Davies; Christine E. Napier; Amelia K. Smit et al.
Source: check_circle
Crossref

Patient perspectives on molecular tumor profiling: “Why wouldn’t you?”

BMC Cancer
2019-12 | Journal article
DOI: 10.1186/s12885-019-5920-x
Contributors: Megan C. Best; Nicole Bartley; Chris Jacobs; Ilona Juraskova; David Goldstein; Ainsley J. Newson; Jacqueline Savard; Bettina Meiser; Mandy Ballinger; Christine Napier et al.
Source: check_circle
Crossref

The PiGeOn project: protocol of a longitudinal study examining psychosocial and ethical issues and outcomes in germline genomic sequencing for cancer

BMC Cancer
2018-12 | Journal article
DOI: 10.1186/s12885-018-4366-x
Contributors: Megan Best; Ainsley J. Newson; Bettina Meiser; Ilona Juraskova; David Goldstein; Kathy Tucker; Mandy L. Ballinger; Dominique Hess; Timothy E. Schlub; Barbara Biesecker et al.
Source: check_circle
Crossref

Estimating TP53 Mutation Carrier Probability in Families with Li-Fraumeni Syndrome Using LFSPRO.

2017-01 | Journal article
DOI: 10.1158/1055-9965.epi-16-0695
PMID: 28137790
Contributors: Peng G; Bojadzieva J; Ballinger ML; Li J; Blackford AL; Mai PL; Savage SA; Thomas DM; Strong LC; Wang W
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?

2017-01 | Journal article
DOI: 10.1007/s10689-016-9964-7
PMID: 28124295
Contributors: McBride KA; Ballinger ML; Schlub TE; Young MA; Tattersall MH; Kirk J; Eeles R; Killick E; Walker LG; Shanley S et al.
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Diagnosis and Management of Hereditary Sarcoma.

2016 | Journal article
DOI: 10.1007/978-3-319-29998-3_10
PMID: 27075354
Contributors: Thomas DM; Ballinger ML
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Sarcoma and germ-line DICER1 mutations - Authors' reply.

2016-11 | Journal article
DOI: 10.1016/s1470-2045(16)30527-7
PMID: 27819238
Contributors: Ballinger ML; Thomas DM; International Sarcoma Kindred Study
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Monogenic and polygenic determinants of sarcoma risk: an international genetic study.

2016-09 | Journal article
DOI: 10.1016/s1470-2045(16)30147-4
PMID: 27498913
Contributors: Ballinger ML; Goode DL; Ray-Coquard I; James PA; Mitchell G; Niedermayr E; Puri A; Schiffman JD; Dite GS; Cipponi A et al.
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counselling for hereditary cancer: a systematic review.

2016-09 | Journal article
DOI: 10.1111/cge.12868
PMID: 27643459
Contributors: Willis AM; Smith SK; Meiser B; Ballinger ML; Thomas DM; Young MA
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

International survey of awareness of genetic risk in the clinical sarcoma community.

2016-06 | Journal article
DOI: 10.1111/ajco.12457
PMID: 26923110
Contributors: McBride KA; Schlub TE; Ballinger ML; Thomas DM; Tattersall MH
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Timing and context: important considerations in the return of genetic results to research participants.

2016-01 | Journal article
DOI: 10.1007/s12687-015-0231-7
PMID: 26004130
PMC: PMC4715816
Contributors: McBride KA; Hallowell N; Tattersall MH; Kirk J; Ballinger ML; Thomas DM; Mitchell G; Young MA
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.

2015-09 | Journal article
DOI: 10.1158/2159-8290.cd-15-0125
PMID: 26084801
PMC: PMC4560660
Contributors: Mirabello L; Koster R; Moriarity BS; Spector LG; Meltzer PS; Gary J; Machiela MJ; Pankratz N; Panagiotou OA; Largaespada D et al.
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Surveillance recommendations for patients with germline TP53 mutations.

2015-07 | Journal article
DOI: 10.1097/cco.0000000000000200
PMID: 26049273
Contributors: Ballinger ML; Mitchell G; Thomas DM
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Clinical implications of genomics for cancer risk genetics.

2015-06 | Journal article
DOI: 10.1016/s1470-2045(15)70026-4
PMID: 26065615
Contributors: Thomas DM; James PA; Ballinger ML
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Etiologic, environmental and inherited risk factors in sarcomas.

2015-04 | Journal article
DOI: 10.1002/jso.23809
PMID: 25335907
Contributors: Thomas DM; Ballinger ML
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Li-Fraumeni syndrome: cancer risk assessment and clinical management.

2014-05 | Journal article
DOI: 10.1038/nrclinonc.2014.41
PMID: 24642672
Contributors: McBride KA; Ballinger ML; Killick E; Kirk J; Tattersall MH; Eeles RA; Thomas DM; Mitchell G
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort.

2013 | Journal article
DOI: 10.1371/journal.pone.0069026
PMID: 23894400
PMC: PMC3718831
Contributors: Mitchell G; Ballinger ML; Wong S; Hewitt C; James P; Young MA; Cipponi A; Pang T; Goode DL; Dobrovic A et al.
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans.

2013 | Journal article
DOI: 10.1016/j.carpath.2012.07.002
PMID: 22999704
Contributors: Osman N; Grande-Allen KJ; Ballinger ML; Getachew R; Marasco S; O'Brien KD; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research.

2013 | Journal article
DOI: 10.1186/2045-3329-3-11
PMID: 23898988
PMC: PMC3751730
Contributors: Young MA; Herlihy A; Mitchell G; Thomas DM; Ballinger M; Tucker K; Lewis CR; Neuhaus S; International Sarcoma Kindred Study; Halliday J
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

2013-07 | Journal article
DOI: 10.1111/jphp.12064
PMID: 23738733
Contributors: Little PJ; Rostam MA; Piva TJ; Getachew R; Kamato D; Guidone D; Ballinger ML; Zheng W; Osman N
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

An increased incidence of Hodgkin's lymphoma in patients with adult-onset sarcoma.

2012 | Journal article
DOI: 10.1186/2045-3329-2-1
PMID: 22588051
PMC: PMC3351710
Contributors: Downing ME; Dite GS; Ballinger ML; International Sarcoma Kindred Study Consortium
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Inherited and de novo germline TP53 mutations in adult-onset sarcoma.

2012 | Journal article
DOI: 10.1186/1897-4287-10-s2-a26
PMC: PMC3326688
Contributors: Thomas DM; Ballinger ML
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Inherited and de novo germline TP53 mutations in adult-onset sarcoma.

2012 | Journal article
DOI: 10.1186/1897-4287-10-s2-a3
PMC: PMC3395324
Contributors: Thomas D; Ballinger M
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Pathogenic germline TP53 mutations in adult sarcoma patients; implications for treatment and screening – description of an upcoming project.

2012 | Journal article
DOI: 10.1186/1897-4287-10-s2-a61
PMC: PMC3327145
Contributors: Mahendran K; Ballinger M; Kirk J; Thomas D; Tattersall M
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.

2012-09 | Journal article
DOI: 10.1016/j.abb.2012.05.025
PMID: 22683649
Contributors: Little PJ; Getachew R; Rezaei HB; Sanchez-Guerrero E; Khachigian LM; Wang H; Liao S; Zheng W; Ballinger ML; Osman N
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL.

2010-09 | Journal article
DOI: 10.1210/en.2010-0027
PMID: 20610572
Contributors: Getachew R; Ballinger ML; Burch ML; Reid JJ; Khachigian LM; Wight TN; Little PJ; Osman N
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor beta type I receptor.

2010-08 | Journal article
DOI: 10.1074/jbc.m109.092767
PMID: 20571025
PMC: PMC2930678
Contributors: Burch ML; Ballinger ML; Yang SN; Getachew R; Itman C; Loveland K; Osman N; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo.

2010-06 | Journal article
DOI: 10.1111/j.1582-4934.2009.00902.x
PMID: 19754668
PMC: PMC3033015
Contributors: Ballinger ML; Osman N; Hashimura K; de Haan JB; Jandeleit-Dahm K; Allen T; Tannock LR; Rutledge JC; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

TGF-beta stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2.

2010-06 | Journal article
DOI: 10.1007/s00018-010-0315-9
PMID: 20213272
Contributors: Burch ML; Yang SN; Ballinger ML; Getachew R; Osman N; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways.

2010-03 | Journal article
DOI: 10.1074/jbc.m109.088674
PMID: 20042606
PMC: PMC2844148
Contributors: Cardoso LE; Little PJ; Ballinger ML; Chan CK; Braun KR; Potter-Perigo S; Bornfeldt KE; Kinsella MG; Wight TN
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Characterisation of Ki11502 as a potent inhibitor of PDGF beta receptor-mediated proteoglycan synthesis in vascular smooth muscle cells.

2010-01 | Journal article
DOI: 10.1016/j.ejphar.2009.09.066
PMID: 19818754
Contributors: Getachew R; Ballinger ML; Burch ML; Little PJ; Osman N
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL.

2009-08 | Journal article
DOI: 10.1016/j.atherosclerosis.2009.01.024
PMID: 19217622
Contributors: Ballinger ML; Ivey ME; Osman N; Thomas WG; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation.

2009-07 | Journal article
DOI: 10.1080/13813450903110754
PMID: 19580379
Contributors: Yang SN; Burch ML; Getachew R; Ballinger ML; Osman N; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Biosynthesis of natural and hyperelongated chondroitin sulfate glycosaminoglycans: new insights into an elusive process.

2008 | Journal article
DOI: 10.2174/1874091x00802010135
PMID: 19238187
PMC: PMC2627520
Contributors: Little PJ; Ballinger ML; Burch ML; Osman N
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis.

2008-12 | Journal article
DOI: 10.2174/187152908786786205
PMID: 19075640
Contributors: Osman N; Ballinger ML; Dadlani HM; Getachew R; Burch ML; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Pyrido-pyrimidine derivative CYC10424 inhibits glycosaminoglycan changes on vascular smooth muscle-derived proteoglycans and reduces lipoprotein binding.

2008-11 | Journal article
DOI: 10.1097/fjc.0b013e31818a8907
PMID: 19033819
Contributors: Ballinger ML; Osman N; Wilks AF; Su S; Burns CJ; Bu X; Little PJ
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central

Phosphorylated troglitazone activates PPARgamma and inhibits vascular smooth muscle cell proliferation and proteoglycan synthesis.

2008-03 | Journal article
DOI: 10.1097/fjc.0b013e3181626ce7
PMID: 18356692
Contributors: Little PJ; Ballinger ML; Survase S; Osman N; Ogru E; Geytenbeek S; Bruemmer D; Nigro J
Source: Self-asserted source
Mandy Ballinger via Europe PubMed Central
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Peer review (1 review for 1 publication/grant)

Review activity for European journal of human genetics (1)
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