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Employment (1)

Sun Yat-sen University: Guangzhou, Guangdong, CN

2018-02-01 to present | Professor (Sun Yat-Sen Memorial Hospital)
Employment
Source: Self-asserted source
Xiaoding Xu

Education and qualifications (2)

Wuhan University: Wuhan, Hubei, CN

2006-09-01 to 2011-12-31 | Ph.D (Department of Chemistry)
Education
Source: Self-asserted source
Xiaoding Xu

Wuhan University: Wuhan, Hubei, CN

2002-09-01 to 2006-07-01 | BS (Department of Chemistry)
Education
Source: Self-asserted source
Xiaoding Xu

Works (26)

Nanoparticles (NPs)-mediated silencing of GSTP1 expression to reverse chemoresistance for effective breast cancer therapy

Journal of Colloid and Interface Science
2025-05 | Journal article
DOI: 10.1016/j.jcis.2025.01.107
Contributors: Qian Shen; Ke Yang; Qingjian Li; Tao Qin; Yunfang Yu; Huangming Hong; Herui Yao; Xiaoding Xu
Source: check_circle
Crossref

Antibody-Decorated Nanoplatform to Reprogram Macrophage and Block Immune Checkpoint LSECtin for Effective Cancer Immunotherapy

Nano Letters
2024-07-17 | Journal article
DOI: 10.1021/acs.nanolett.4c02139
Contributors: Rui Xu; Xiangya Liu; Yuxuan Zhang; Guo Wu; Linzhuo Huang; Rong Li; Xiaoding Xu
Source: check_circle
Crossref

Redox‐Responsive Polymeric Nanoparticle for Nucleic Acid Delivery and Cancer Therapy: Progress, Opportunities, and Challenges

Macromolecular Bioscience
2024-03 | Journal article
DOI: 10.1002/mabi.202300238
Contributors: Lei Xu; Yuan Cao; Ya Xu; Rong Li; Xiaoding Xu
Source: check_circle
Crossref

Remodeling of Mitochondrial Metabolism by a Mitochondria‐Targeted RNAi Nanoplatform for Effective Cancer Therapy

Small
2024-03 | Journal article
DOI: 10.1002/smll.202305923
Contributors: Rui Xu; Linzhuo Huang; Jiayu Liu; Yuxuan Zhang; Ya Xu; Rong Li; Shicheng Su; Xiaoding Xu
Source: check_circle
Crossref

Role of long non-coding RNAs in cancer: From subcellular localization to nanoparticle-mediated targeted regulation

Molecular Therapy - Nucleic Acids
2023-09 | Journal article
DOI: 10.1016/j.omtn.2023.07.009
Contributors: Chunfang Wei; Ya Xu; Qian Shen; Rong Li; Xiaoyun Xiao; Phei Er Saw; Xiaoding Xu
Source: check_circle
Crossref

Nanoparticles (NPs)-mediated lncBCMA silencing to promote eEF1A1 ubiquitination and suppress breast cancer growth and metastasis

Acta Pharmaceutica Sinica B
2023-08 | Journal article
DOI: 10.1016/j.apsb.2022.12.004
Contributors: Ke Yang; Lei Xu; Ying Xu; Qian Shen; Tao Qin; Yunfang Yu; Yan Nie; Herui Yao; Xiaoding Xu
Source: check_circle
Crossref

Repolarization of macrophages to improve sorafenib sensitivity for combination cancer therapy

Acta Biomaterialia
2023-05 | Journal article
DOI: 10.1016/j.actbio.2023.03.014
Contributors: Linzhuo Huang; Rui Xu; Weirong Li; Li Lv; Chunhao Lin; Xianzhu Yang; Yandan Yao; Phei Er Saw; Xiaoding Xu
Source: check_circle
Crossref

Nanoparticles (NPs)-mediated systemic mRNA delivery to reverse trastuzumab resistance for effective breast cancer therapy

Acta Pharmaceutica Sinica B
2023-03 | Journal article
DOI: 10.1016/j.apsb.2022.09.021
Contributors: Zhihui Dong; Zhuoshan Huang; Senlin Li; Ying Wang; Yandan Yao; Xianzhu Yang; Xiaoding Xu
Source: check_circle
Crossref

Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling

Journal of Experimental & Clinical Cancer Research
2023-03-11 | Journal article
DOI: 10.1186/s13046-023-02618-z
Part of ISSN: 1756-9966
Contributors: Zixian Huang; Xi Rui; Chen Yi; Yongju Chen; Rui Chen; Yancan Liang; Yan Wang; Weicheng Yao; Xiaoding Xu; Zhiquan Huang
Source: Self-asserted source
Xiaoding Xu

Supramolecular peptide hydrogel doped with nanoparticles for local siRNA delivery and diabetic wound healing

Chemical Engineering Journal
2023-02 | Journal article
DOI: 10.1016/j.cej.2022.141244
Contributors: Liangyan Wu; Yanbo Chen; Gang Zeng; Na Mao; Na Li; Lanlan Li; Xiaoding Xu; Li Yan
Source: check_circle
Crossref

HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway

Advanced Science
2023-01 | Journal article
DOI: 10.1002/advs.202202437
Part of ISSN: 2198-3844
Part of ISSN: 2198-3844
Contributors: Zixian Huang; Yongju Chen; Rui Chen; Bin Zhou; Yongqiang Wang; Lei Hong; Yuepeng Wang; Jianguang Wang; Xiaoding Xu; Zhiquan Huang et al.
Source: Self-asserted source
Xiaoding Xu

Nucleus‐specific RNAi nanoplatform for targeted regulation of nuclear lncRNA function and effective cancer therapy

Exploration
2022-10 | Journal article
DOI: 10.1002/EXP.20220013
Contributors: Zixian Huang; Shaomin Liu; Nan Lu; Lei Xu; Qian Shen; Zhuoshan Huang; Zhiquan Huang; Phei Er Saw; Xiaoding Xu
Source: check_circle
Crossref

LCDR regulates the integrity of lysosomal membrane by hnRNP K–stabilized LAPTM5 transcript and promotes cell survival

Proceedings of the National Academy of Sciences
2022-02 | Journal article | Author
DOI: 10.1073/pnas.2110428119
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Xiwang Yang; Ya Wen; Shaomin Liu; Liqiang Duan; Tongfeng Liu; zhou tong; Zhuo Wang; Yinmin Gu; Yibo Xi; Xiaodong Wang et al.
Source: Self-asserted source
Xiaoding Xu

LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer

Cancer Research
2022-02-15 | Journal article | Author
DOI: 10.1158/0008-5472.can-21-1446
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Ying Xu; Wei Ren; Qingjian Li; Chaohui Duan; Xiaorong Lin; Zhuofei Bi; Kaiyun You; Qian Hu; Ning Xie; Yunfang Yu et al.
Source: Self-asserted source
Xiaoding Xu

Reduction-responsive RNAi nanoplatform to reprogram tumor lipid metabolism and repolarize macrophage for combination pancreatic cancer therapy

Biomaterials
2022-01 | Journal article
DOI: 10.1016/j.biomaterials.2021.121264
Contributors: Shuwen Cao; Phei Er Saw; Qian Shen; Rong Li; Yun Liu; Xiaoding Xu
Source: check_circle
Crossref

A siRNA-Assisted Assembly Strategy to Simultaneously Suppress “Self” and Upregulate “Eat-Me” Signals for Nanoenabled Chemo-Immunotherapy

ACS Nano
2021-10-26 | Journal article
DOI: 10.1021/acsnano.1c04458
Contributors: Yuxi Zhang; Zhenghai Zhang; Senlin Li; Liang Zhao; Dongdong Li; Ziyang Cao; Xiaoding Xu; Xianzhu Yang
Source: check_circle
Crossref

Nanoparticle-Mediated Inhibition of Mitochondrial Glutaminolysis to Amplify Oxidative Stress for Combination Cancer Therapy

Nano Letters
2021-09-22 | Journal article
DOI: 10.1021/acs.nanolett.1c02073
Contributors: Lei Xu; Rui Xu; Phei Er Saw; Jun Wu; Si-Xue Cheng; Xiaoding Xu
Source: check_circle
Crossref

Biomedical Applications of a Novel Class of High-Affinity Peptides

Accounts of Chemical Research
2021-09-21 | Journal article
DOI: 10.1021/acs.accounts.1c00239
Contributors: Phei Er Saw; Xiaoding Xu; Sunghyun Kim; Sangyong Jon
Source: check_circle
Crossref

Mitochondria-specific delivery system for targeted regulation of mitochondrial gene expression

STAR Protocols
2021-03 | Journal article
DOI: 10.1016/j.xpro.2020.100275
Part of ISSN: 2666-1667
Contributors: Shicheng Su; Shuwen Cao; Jiayu Liu; Xiaoding Xu
Source: Self-asserted source
Xiaoding Xu

Non-coding RNAs: the new central dogma of cancer biology

Science China Life Sciences
2021-01 | Journal article
DOI: 10.1007/s11427-020-1700-9
Part of ISSN: 1674-7305
Part of ISSN: 1869-1889
Contributors: Phei Er Saw; Xiaoding Xu; Jianing Chen; Er-Wei Song
Source: Self-asserted source
Xiaoding Xu

LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network

Theranostics
2020 | Journal article
DOI: 10.7150/thno.47830
Part of ISSN: 1838-7640
Contributors: Yin Zhang; Yong-Xin Huang; Dan-Lan Wang; Bing Yang; Hai-Yan Yan; Le-Hang Lin; Yun Li; Jie Chen; Li-Min Xie; Yong-Sheng Huang et al.
Source: Self-asserted source
Xiaoding Xu

Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

Cell
2020-10 | Journal article | Author
DOI: 10.1016/j.cell.2020.08.009
Part of ISSN: 0092-8674
Contributors: Qiyi Zhao; Jiayu Liu; Hong Deng; Ruiying Ma; Jian-You Liao; Huixin Liang; Jingxiong Hu; Jiaqian Li; Zhiyong Guo; Junchao Cai et al.
Source: Self-asserted source
Xiaoding Xu

Nanoparticles (NPs)‐Meditated LncRNA AFAP1‐AS1 Silencing to Block Wnt/ <i>β</i> ‐Catenin Signaling Pathway for Synergistic Reversal of Radioresistance and Effective Cancer Radiotherapy

Advanced Science
2020-09 | Journal article | Author
DOI: 10.1002/advs.202000915
Part of ISSN: 2198-3844
Part of ISSN: 2198-3844
Contributors: Zhuofei Bi; Qingjian Li; Xiaoxiao Dinglin; Ying Xu; Kaiyun You; Huangming Hong; Qian Hu; Wei Zhang; Chenchen Li; Yujie Tan et al.
Source: Self-asserted source
Xiaoding Xu

Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy

Nano Letters
2020-07-08 | Journal article
DOI: 10.1021/acs.nanolett.0c00757
Contributors: Yujing Li; Jianxun Ding; Xiaoding Xu; Run Shi; Phei Er Saw; Junqing Wang; Shirley Chung; Wenliang Li; Bader M. Aljaeid; Robert J. Lee et al.
Source: check_circle
Crossref

Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy

Biomaterials
2020-03 | Journal article
DOI: 10.1016/j.biomaterials.2020.119760
Part of ISSN: 0142-9612
Contributors: Senlin Li; Phei Er Saw; Chunhao Lin; Yan Nie; Wei Tao; Omid C. Farokhzad; Lei Zhang; Xiaoding Xu
Source: Self-asserted source
Xiaoding Xu

Stimuli-Responsive Polymer–Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy

Nano Letters
2019-09-11 | Journal article
DOI: 10.1021/acs.nanolett.9b01660
Contributors: Phei Er Saw; Herui Yao; Chunhao Lin; Wei Tao; Omid C Farokhzad; Xiaoding Xu
Source: check_circle
Crossref

Peer review (97 reviews for 28 publications/grants)

Review activity for ACS applied bio materials. (3)
Review activity for ACS applied materials & interfaces. (11)
Review activity for ACS applied nano materials. (4)
Review activity for ACS biomaterials science & engineering. (4)
Review activity for ACS nano. (20)
Review activity for Acta biomaterialia. (5)
Review activity for Advanced healthcare materials (4)
Review activity for Advanced materials. (1)
Review activity for Advanced nanoBiomed research. (1)
Review activity for Advanced science. (1)
Review activity for Advanced therapeutics. (1)
Review activity for Biochemical and biophysical research communications. (1)
Review activity for Biomaterials. (7)
Review activity for Carbohydrate polymers. (2)
Review activity for Chemical engineering journal. (5)
Review activity for International journal of biological macromolecules. (1)
Review activity for International journal of pharmaceutics (1)
Review activity for iScience. (2)
Review activity for Journal of agricultural and food chemistry. (2)
Review activity for Journal of controlled release. (5)
Review activity for Langmuir : (1)
Review activity for Life sciences. (1)
Review activity for Macromolecular bioscience. (2)
Review activity for Macromolecular rapid communications. (2)
Review activity for Molecular pharmaceutics. (3)
Review activity for Nano letters. (2)
Review activity for Nano today. (1)
Review activity for Small. (4)
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