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Institut Pasteur: Paris, Île-de-France, FR

2014-09-01 to present | research assistant (immunologie)
Employment
Source: Self-asserted source
laure guenin-mace

Works (33)

Preclinical proof of principle for orally delivered Th17 antagonist miniproteins

Cell
2024 | Journal article
DOI: 10.1016/j.cell.2024.05.052
EID:

2-s2.0-85198337559

Part of ISSN: 10974172 00928674
Contributors: Berger, S.; Seeger, F.; Yu, T.-Y.; Aydin, M.; Yang, H.; Rosenblum, D.; Guenin-Macé, L.; Glassman, C.; Arguinchona, L.; Sniezek, C. et al.
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Immune-Epithelial Cross Talk in Regeneration and Repair

Annual Review of Immunology
2023 | Book
DOI: 10.1146/annurev-immunol-101721-062818
EID:

2-s2.0-85159252189

Part of ISSN: 15453278 07320582
Contributors: Guenin-Mace, L.; Konieczny, P.; Naik, S.
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Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples

Methods in Molecular Biology
2022 | Book chapter
DOI: 10.1007/978-1-0716-1779-3_13
EID:

2-s2.0-85117527401

Part of ISSN: 19406029 10643745
Contributors: Rifflet, A.; Demangel, C.; Guenin-Macé, L.
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for mycobacterium tuberculosis

eLife
2021 | Journal article
DOI: 10.7554/eLife.71946
EID:

2-s2.0-85122003923

Part of ISSN: 2050084X
Contributors: Laval, T.; Pedró-Cos, L.; Malaga, W.; Guenin-Macé, L.; Pawlik, A.; Mayau, V.; Yahia-Cherbal, H.; Delos, O.; Frigui, W.; Bertrand-Michel, J. et al.
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

bioRxiv
2021 | Other
DOI: 10.1101/2021.07.08.451715
EID:

2-s2.0-85113967658

Part of ISSN: 26928205
Contributors: Laval, T.; Pedró-Cos, L.; Malaga, W.; Guenin-Macé, L.; Pawlik, A.; Mayau, V.; Yahia-Cherbal, H.; Frigui, W.; Bertrand-Michel, J.; Guilhot, C. et al.
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Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

Frontiers in Pharmacology
2021 | Journal article
DOI: 10.3389/fphar.2021.733496
EID:

2-s2.0-85116335099

Part of ISSN: 16639812
Contributors: Tello Rubio, B.; Bugault, F.; Baudon, B.; Raynal, B.; Brûlé, S.; Morel, J.-D.; Saint-Auret, S.; Blanchard, N.; Demangel, C.; Guenin-Macé, L.
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Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

JCI Insight
2020 | Journal article
DOI: 10.1172/jci.insight.140598
EID:

2-s2.0-85093539157

Part of ISSN: 23793708
Contributors: Guenin-Macé, L.; Morel, J.-D.; Doisne, J.-M.; Schiavo, A.; Boulet, L.; Mayau, V.; Goncalves, P.; Duchatelet, S.; Hovnanian, A.; Bondet, V. et al.
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Dysregulation of tryptophan catabolism at the host-skin microbiota interface in Hidradenitis Suppurativa

medRxiv
2020 | Other
DOI: 10.1101/2020.08.25.20181438
EID:

2-s2.0-85099533293
Contributors: Guenin-Macé, L.; Morel, J.-D.; Doisne, J.-M.; Schiavo, A.; Boulet, L.; Mayau, V.; Goncalves, P.; Duchatelet, S.; Hovnanian, A.; Bondet, V. et al.
Source: Self-asserted source
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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Nature Communications
2020 | Journal article
DOI: 10.1038/s41467-020-19931-2
EID:

2-s2.0-85097446964

Part of ISSN: 20411723
Contributors: Chevalier, G.; Siopi, E.; Guenin-Macé, L.; Pascal, M.; Laval, T.; Rifflet, A.; Boneca, I.G.; Demangel, C.; Colsch, B.; Pruvost, A. et al.
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Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

PLoS neglected tropical diseases
2020 | Journal article
DOI: 10.1371/journal.pntd.0008878
EID:

2-s2.0-85097121745

Part of ISSN: 19352735
Contributors: Colucci-Guyon, E.; Rifflet, A.; Saint-Auret, S.; da Costa, A.; Boucontet, L.; Laval, T.; Prehaud, C.; Blanchard, N.; Levraud, J.-P.; Boneca, I.G. et al.
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Mycolactone: More than just a cytotoxin

Buruli Ulcer: Mycobacterium Ulcerans Disease
2019 | Book chapter
Part of DOI: 10.1007/978-3-030-11114-4_7
EID:

2-s2.0-85083669230

Part of ISBN: 9783030111144 9783030111137
Contributors: Guenin-Macé, L.; Ruf, M.-T.; Pluschke, G.; Demangel, C.
Source: Self-asserted source
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Mycolactone: More than Just a Cytotoxin

Buruli Ulcer
2019 | Book chapter
DOI: 10.1007/978-3-030-11114-4_7
Part of ISBN: 9783030111137
Part of ISBN: 9783030111144
Contributors: Laure Guenin-Macé; Marie-Thérèse Ruf; Gerd Pluschke; Caroline Demangel
Source: Self-asserted source
laure guenin-mace

The impact of gut microbiota on depressive-like behaviors and adult hippocampal neurogenesis requires the endocannabinoid system

bioRxiv
2019 | Other
DOI: 10.1101/718288
EID:

2-s2.0-85095478688

Part of ISSN: 26928205
Contributors: Chevalier, G.; Siopi, E.; Guenin-Macé, L.; Pascal, M.; Laval, T.; Rifflet, A.; Boneca, I.G.; Demangel, C.; Leulier, F.; Lepousez, G. et al.
Source: Self-asserted source
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HOST IMMUNOMODULATION BY MYCOLACTONE, THE MYCOBACTERIUM ULCERANS TOXIN

Toxicon
2018 | Journal article
DOI: 10.1016/J.TOXICON.2017.12.018
WOSUID: WOS:000436917900027
Contributors: Demangel, Caroline; Guenin-Mace, Laure; Baron, Ludivine; Morel, Jean-David
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Proteomics reveals scope of mycolactone-mediated sec61 blockade and distinctive stress signature

Molecular and Cellular Proteomics
2018 | Journal article
DOI: 10.1074/mcp.RA118.000824
EID:

2-s2.0-85052639546

Part of ISSN: 15359484 15359476
Contributors: Morel, J.-D.; Paatero, A.O.; Wei, J.; Yewdell, J.W.; Guenin-Macé, L.; Van Haver, D.; Impens, F.; Pietrosemoli, N.; Paavilainen, V.O.; Demangel, C.
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Modular total syntheses of mycolactone A/B and its [<sup>2</sup>H]-isotopologue

Organic and Biomolecular Chemistry
2017 | Journal article
DOI: 10.1039/c7ob01943b
EID:

2-s2.0-85029749037

Part of ISSN: 14770520
Contributors: Saint-Auret, S.; Abdelkafi, H.; Le Nouen, D.; Guenin-Macé, L.; Demangel, C.; Bisseret, P.; Blanchard, N.
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Mycolactone displays anti-inflammatory effects on the nervous system

PLoS Neglected Tropical Diseases
2017 | Journal article
DOI: 10.1371/journal.pntd.0006058
EID:

2-s2.0-85036644845

Part of ISSN: 19352735 19352727
Contributors: Isaac, C.; Mauborgne, A.; Grimaldi, A.; Ade, K.; Pohl, M.; Limatola, C.; Boucher, Y.; Demangel, C.; Guenin-Macé, L.
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Mycolactone subverts immunity by selectively blocking the Sec61 translocon

Journal of Experimental Medicine
2016 | Journal article
DOI: 10.1084/jem.20160662
EID:

2-s2.0-85008517628

Part of ISSN: 15409538 00221007
Contributors: Baron, L.; Paatero, A.O.; Morel, J.-D.; Impens, F.; Guenin-Macé, L.; Saint-Auret, S.; Blanchard, N.; Dillmann, R.; Niang, F.; Pellegrini, S. et al.
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Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Scientific Reports
2015 | Journal article
DOI: 10.1038/srep17693
EID:

2-s2.0-84949294595

Part of ISSN: 20452322
Contributors: Niang, F.; Sarfo, F.S.; Frimpong, M.; Guenin-Macé, L.; Wansbrough-Jones, M.; Stinear, T.; Phillips, R.O.; Demangel, C.
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Shaping mycolactone for therapeutic use against inflammatory disorders

Science Translational Medicine
2015 | Journal article
DOI: 10.1126/scitranslmed.aab0458
EID:

2-s2.0-84930177066

Part of ISSN: 19466242 19466234
Contributors: Guenin-Macé, L.; Baron, L.; Chany, A.-C.; Tresse, C.; Saint-Auret, S.; Jönsson, F.; Le Chevalier, F.; Bruhns, P.; Bismuth, G.; Hidalgo-Lucas, S. et al.
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Pathogenesis of skin ulcers: Lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

Cellular and Molecular Life Sciences
2014 | Journal article
DOI: 10.1007/s00018-014-1561-z
EID:

2-s2.0-84903272230

Part of ISSN: 14209071 1420682X
Contributors: Guenin-Macé, L.; Oldenburg, R.; Chrétien, F.; Demangel, C.
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Synthetic variants of mycolactone bind and activate Wiskott-Aldrich syndrome proteins

Journal of Medicinal Chemistry
2014 | Journal article
DOI: 10.1021/jm5008819
EID:

2-s2.0-84907212348

Part of ISSN: 15204804 00222623
Contributors: Chany, A.-C.; Veyron-Churlet, R.; Tresse, C.; Mayau, V.; Casarotto, V.; Le Chevalier, F.; Guenin-Macé, L.; Demangel, C.; Blanchard, N.
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Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

Journal of Clinical Investigation
2013 | Journal article
DOI: 10.1172/JCI66576
EID:

2-s2.0-84875858308

Part of ISSN: 00219738 15588238
Contributors: Guenin-Macé, L.; Veyron-Churlet, R.; Thoulouze, M.-I.; Romet-Lemonne, G.; Hong, H.; Leadlay, P.F.; Danckaert, A.; Ruf, M.-T.; Mostowy, S.; Zurzolo, C. et al.
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First structure activity relationship of the mycolactones analogs

Abstracts of Papers of the American Chemical Society
2012 | Journal article
WOSUID: WOS:000324621805661
Contributors: Blanchard, Nicolas; Eustache, Jacques; Demangel, Caroline; Guenin-Mace, Laure; Tarnus, Celine; Schmitt, Marjorie; Mirguet, Olivier; Tresse, Cedric; Casarotto, Virginie; Chany, Anne-Caroline
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A diverted total synthesis of mycolactone analogues: An insight into buruli ulcer toxins

Chemistry - A European Journal
2011 | Journal article
DOI: 10.1002/chem.201102542
EID:

2-s2.0-83755195577

Part of ISSN: 09476539 15213765
Contributors: Chany, A.-C.; Casarotto, V.; Schmitt, M.; Tarnus, C.; Guenin-Macé, L.; Demangel, C.; Mirguet, O.; Eustache, J.; Blanchard, N.
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Mycolactone diffuses into the peripheral blood of buruli ulcer patients - implications for diagnosis and disease monitoring

PLoS Neglected Tropical Diseases
2011 | Journal article
DOI: 10.1371/journal.pntd.0001237
EID:

2-s2.0-79960956034

Part of ISSN: 19352727 19352735
Contributors: Sarfo, F.S.; Chevalier, F.; Aka, N.; Phillips, R.O.; Amoako, Y.; Boneca, I.G.; Lenormand, P.; Dosso, M.; Wansbrough-Jones, M.; Veyron-Churlet, R. et al.
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Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

Proceedings of the National Academy of Sciences of the United States of America
2011 | Journal article
DOI: 10.1073/pnas.1016496108
EID:

2-s2.0-79961212934

Part of ISSN: 00278424 10916490
Contributors: Guenin-Macé, L.; Carrette, F.; Asperti-Boursin, F.; Le Bon, A.; Caleechurn, L.; Di Bartolo, V.; Fontanet, A.; Bismuth, G.; Demangel, C.
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Expression profiling of prospero in the Drosophila larval chemosensory organ: Between growth and outgrowth

BMC Genomics
2010 | Journal article
DOI: 10.1186/1471-2164-11-47
EID:

2-s2.0-77349110017

Part of ISSN: 14712164
Contributors: Guenin, L.; Raharijaona, M.; Houlgatte, R.; Baba-Aissa, F.
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Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events

Journal of Immunology
2010 | Journal article
DOI: 10.4049/jimmunol.0902854
EID:

2-s2.0-77949318100

Part of ISSN: 00221767 15506606
Contributors: Boulkroun, S.; Guenin-Macé, L.; Thoulouze, M.-I.; Monot, M.; Merckx, A.; Langsley, G.; Bismuth, G.; Di Bartolo, V.; Demangel, C.
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Immunosuppressive signature of cutaneous mycobacterium ulcerans infection in the peripheral blood of patients with buruli ulcer disease

Journal of Infectious Diseases
2009 | Journal article
DOI: 10.1086/646615
EID:

2-s2.0-72849153503

Part of ISSN: 00221899
Contributors: Phillips, R.; Sarfo, F.S.; Guenin-Macé, L.; Decalf, J.; Wansbrough-Jones, M.; Albert, M.L.; Demangel, C.
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Lipids of pathogenic mycobacteria: Contributions to virulence and host immune suppression

Transboundary and Emerging Diseases
2009 | Journal article
DOI: 10.1111/j.1865-1682.2009.01072.x
EID:

2-s2.0-68149122260

Part of ISSN: 18651674 18651682
Contributors: Guenin-Macé, L.; Siméone, R.; Demangel, C.
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Prospero mutants induce precocious sexual behavior in Drosophila males

Behavior Genetics
2007 | Journal article
DOI: 10.1007/s10519-007-9152-5
EID:

2-s2.0-34250749672

Part of ISSN: 00018244
Contributors: Grosjean, Y.; Guenin, L.; Bardet, H.-M.; Ferveur, J.-F.
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Spatio-temporal expression of Prospero is finely tuned to allow the correct development and function of the nervous system in Drosophila melanogaster

Developmental Biology
2007 | Journal article
DOI: 10.1016/j.ydbio.2006.12.016
EID:

2-s2.0-33947114835

Part of ISSN: 00121606
Contributors: Guenin, L.; Grosjean, Y.; Fraichard, S.; Acebes, A.; Baba-Aissa, F.; Ferveur, J.-F.
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