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NETs, Extracellular traps, Neutrophils, Basophils, BETs, Eosinophils, EETs, Asthma, Allergy
Switzerland

Biography

We are interested in molecular mechanisms that control inflammation, and granulocyte functions. Specifically we are studying the anti-microbial defense mechanisms and release of inflammatory mediators by granulocytes. Extracellular DNA trap formation by granulocytes is a newly defined anti-microbial mechanism. Previous reports from our group revealed that extracellular DNA trap formation by neutrophils, eosinophils, and basophils does not require their cell death, and DNA traps are composed of mitochondrial DNA and granule proteins. Our aim is to investigate molecular events required for programmed mtDNA release during extracellular DNA trap formation in mouse and human neutrophils. Our group has collaborations with scientists and clinicians from many international and local academic institutions.

Activities

Employment (7)

University of Bern: Bern, CH

2009-01-01 to present | Associate Professor (Pharmacology)
Employment
Source: Self-asserted source
Shida Yousefi

University of Bern: Bern, CH

2005-01-01 to 2009-02-02 | Assistant Professor (Dozentin I) (Pharmacology)
Employment
Source: Self-asserted source
Shida Yousefi

University of Bern: Bern, CH

2004-01-01 to 2005-02-02 | Lecturer (Dozentin II) (Pharmacology)
Employment
Source: Self-asserted source
Shida Yousefi

University of Bern: Bern, CH

2000-01-01 to 2004-02-02 | Senior Scientist (Oberassistentin) (Pharmacology)
Employment
Source: Self-asserted source
Shida Yousefi

Sunnybrook Research Institute: Toronto, ON, CA

1992-09-01 to 1993-09-01 | Research Assistant (Cancer Research)
Employment
Source: Self-asserted source
Shida Yousefi

Lunenfeld-Tanenbaum Research Institute: Toronto, ON, CA

1988-01-01 to 1992-02-02 | Assitant Researcher (Cancer research)
Employment
Source: Self-asserted source
Shida Yousefi

Lady Davis Institute for Medical Research: Montreal, QC, CA

1986-01-01 to 1988-02-02 | Assistant Researcher (Cancer research)
Employment
Source: Self-asserted source
Shida Yousefi

Education and qualifications (6)

University of Bern: Bern, CH

2005-01-01 to 2005-02-02 | Venia legendi (Habilitation) (Pharmacology)
Education
Source: Self-asserted source
Shida Yousefi

Novartis Horsham Research Centre: Horsham, West Sussex, GB

1997-12-30 to 2000-09-01 | Postdoctoral fellowship (Molecular and Cell Biology Unit, Expression Profiling Lab.)
Education
Source: Self-asserted source
Shida Yousefi

University of Toronto: Toronto, ON, CA

1996-09-01 to 1997-12-30 | Postdoctoral fellowship (Infection & Immunology)
Education
Source: Self-asserted source
Shida Yousefi

University of Zurich: Zürich, CH

1993-09-01 to 1996-06-30 | Ph.D. (Biochemistry)
Education
Source: Self-asserted source
Shida Yousefi

University of Minnesota System: Minneapolis, MN, US

1984-09-01 to 1986-06-01 | M.Sc. (Microbiology)
Education
Source: Self-asserted source
Shida Yousefi

University of Minnesota System: Minneapolis, MN, US

1979-09-01 to 1983-06-01 | B.Sc. (Microbiology)
Education
Source: Self-asserted source
Shida Yousefi

Funding (7)

Molecular mechanisms of neutrophil extracellular trap (NET) formation

2017-05 to 2021-05 | Grant
National Science Foundation (Basel, Basel, CH)
GRANT_NUMBER:

31003A_173215

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of extracellular DNA trap formation by granulocytes

2013-04 to present | Grant
Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Basel, CH)
GRANT_NUMBER:

310030_146215

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of granulocyte activation

2009-11 to 2013-11 | Grant
Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Basel, CH)
GRANT_NUMBER:

310030_127628

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of granulocyte activation

2006-04 to 2009-04 | Grant
Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Basel, CH)
GRANT_NUMBER:

310030-112078

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of neutrophil activation

2002-10 to 2005-10 | Grant
Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Basel, CH)
GRANT_NUMBER:

3100-068449

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of neutrophil activation

2002-01 to 2003-01 | Grant
Novartis Stiftung für Medizinisch-Biologische Forschung (Basel, CH)
GRANT_NUMBER:

02B16

Source: Self-asserted source
Shida Yousefi

Molecular mechanisms of granulocyte activation

2002-01 to 2003 | Grant
Novartis Stiftung für Medizinisch-Biologische Forschung (Basel, CH)
GRANT_NUMBER:

Nr. 02B16

Source: Self-asserted source
Shida Yousefi

Peer review (3 reviews for 2 publications/grants)

Review activity for Archivum Immunologiae et Therapiae Experimentalis : (1)
Review activity for Cell death and disease. (2)