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ResearcherID: J-3659-2012

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Aarhus University: Aarhus, DK

Professor (Department of Chemistry)
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Source: Self-asserted source
Alexander Zelikin

Works (50 of 143)

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Page 1 of 3

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials
2025-03-24 | Journal article
DOI: 10.1002/adfm.202503381
Contributors: Dante G. Andersen; Andreas B. Pedersen; Mireia Casanovas Montasell; Søren Moesgaard; Anja Bille Bohn; Alexander N. Zelikin
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Crossref

Receptor-Mediated Transmembrane Activation of Protein Folding in Synthetic Cells

Bioconjugate Chemistry
2025-03-17 | Journal article
DOI: 10.1021/acs.bioconjchem.5c00043
Contributors: Andreas Bo̷tker Pedersen; Dante Guldbrandsen Andersen; Josefine Hammer Jakobsen; Mireia Casanovas Montasell; Alexander N. Zelikin
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Crossref

Artificial Internalizing Receptors: Intracellular Delivery of Cargo Through Bio‐Orthogonal Recognition

Advanced Healthcare Materials
2024-12 | Journal article
DOI: 10.1002/adhm.202402472
Contributors: Ane Bretschneider Søgaard; Rikke Fabech Hansson; Anne Selch Tvilum; Alexander N. Zelikin
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Crossref

Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells

Advanced Functional Materials
2024-08 | Journal article
DOI: 10.1002/adfm.202400048
Contributors: Ane Bretschneider Søgaard; Frederik Skovbo; Anne Tvilum; Rikke F. Hansson; Alexander N. Zelikin
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Crossref

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology
2024-05-20 | Journal article
DOI: 10.1002/adbi.202400053
Contributors: Ane Bretschneider Søgaard; Kaja Borup Løvschall; Mireia Casanovas Montasell; Clara Bakkegaard Cramer; Pere Monge Marcet; Andreas Bøtker Pedersen; Josefine Hammer Jakobsen; Alexander N. Zelikin
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Chemical Zymogens and Transmembrane Activation of Transcription in Synthetic Cells

Advanced Materials
2024-02 | Journal article
DOI: 10.1002/adma.202309385
Contributors: Dante Guldbrandsen Andersen; Andreas Bøtker Pedersen; Martin Høgholm Jørgensen; Mireia Casanovas Montasell; Ane Bretschneider Søgaard; Gal Chen; Avi Schroeder; Gregers Rom Andersen; Alexander N. Zelikin
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Crossref

Chemical Zymogens: Specificity and Steroidal Control of Reactivation

ChemBioChem
2023-08 | Journal article
DOI: 10.1002/cbic.202300304
Contributors: Mireia Casanovas Montasell; Anna Baumann; Alexander N. Zelikin
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Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization

ACS Macro Letters
2023-07-18 | Journal article
DOI: 10.1021/acsmacrolett.3c00345
Contributors: Maria Merrild Kristensen; Kaja Borup Løvschall; Alexander N. Zelikin
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Crossref

Editorial for the Special Issue ‘Synthetic Biology and Biomimicry'

Small
2023-03 | Journal article
DOI: 10.1002/smll.202301160
Contributors: Alexander N. Zelikin; Ebbe Sloth Andersen; Brigitte Städler
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Crossref

Transmembrane signaling by a synthetic receptor in artificial cells

Nature Communications
2023-03-24 | Journal article
DOI: 10.1038/s41467-023-37393-0
Contributors: Ane Bretschneider Søgaard; Andreas Bøtker Pedersen; Kaja Borup Løvschall; Pere Monge; Josefine Hammer Jakobsen; Leila Džabbarova; Line Friis Nielsen; Sandra Stevanovic; Raoul Walther; Alexander N. Zelikin
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Crossref

Chemical zymogens for the protein cysteinome

Nature Communications
2022-08-18 | Journal article
DOI: 10.1038/s41467-022-32609-1
Contributors: Mireia Casanovas Montasell; Pere Monge; Sheiliza Carmali; Livia Mesquita Dias Loiola; Dante Guldbrandsen Andersen; Kaja Borup Løvschall; Ane Bretschneider Søgaard; Maria Merrild Kristensen; Jean Maurice Pütz; Alexander N. Zelikin
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Crossref

Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability

Bioconjugate Chemistry
2022-04-20 | Journal article
DOI: 10.1021/acs.bioconjchem.2c00034
Contributors: Mirja Harms; Rikke Fabech Hansson; Sheiliza Carmali; Yasser Almeida-Hernández; Elsa Sanchez-Garcia; Jan Münch; Alexander N. Zelikin
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Synthetic Artificial Apoptosis‐Inducing Receptor for On‐Demand Deactivation of Engineered Cells

Advanced Science
2021-07 | Journal article
DOI: 10.1002/advs.202004432
Contributors: Pere Monge; Kaja Borup Løvschall; Ane Bretschneider Søgaard; Raoul Walther; Thaddeus W. Golbek; Lars Schmüser; Tobias Weidner; Alexander N. Zelikin
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Crossref

Green self-immolative polymer: molecular antenna to collect and propagate the signal for zymogen activation

2021-07-25 | Other
DOI: 10.1101/2021.07.25.453687
Contributors: Mireia Casanovas Montasell; Pere Monge; Sheiliza Carmali; Livia Mesquita Dias Loiola; Dante Guldbrandsen Andersen; Kaja Borup Løvschall; Ane Bretschneider Søgaard; Maria Merrild Kristensen; Jean Maurice Pütz; Alexander N. Zelikin
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Crossref

Transmembrane signalling by a bionic receptor: biological input and output, chemical mechanism of signal transduction

2021-07-25 | Other
DOI: 10.1101/2021.07.25.453684
Contributors: Kaja B. Løvschall; Pere Monge; Line F. Nielsen; Sandra Stevanovic; Raoul Walther; Alexander N. Zelikin
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Crossref

Per‐glycosylation of the Surface‐Accessible Lysines: One‐Pot Aqueous Route to Stabilized Proteins with Native Activity

ChemBioChem
2021-07-15 | Journal article
DOI: 10.1002/cbic.202100228
Contributors: Raoul Walther; Pere Monge; Andreas Bøtker Pedersen; Anja Benderoth; Jannik Nedergaard Pedersen; Azad Farzadfard; Ole A. Mandrup; Kenneth A. Howard; Daniel E. Otzen; Alexander N. Zelikin
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Crossref

Ceria Nanozyme and Phosphate Prodrugs: Drug Synthesis through Enzyme Mimicry

ACS Applied Materials & Interfaces
2021-06-09 | Journal article
DOI: 10.1021/acsami.1c03890
Contributors: Raoul Walther; Tin H. Huynh; Pere Monge; Anne Sofie Fruergaard; Aref Mamakhel; Alexander N. Zelikin
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Crossref

Nitric Oxide to Fight Viral Infections

Advanced Science
2021-04 | Journal article
DOI: 10.1002/advs.202003895
Contributors: Fabio Lisi; Alexander N. Zelikin; Rona Chandrawati
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Crossref

Broad‐Spectrum Antiviral Agents Based on Multivalent Inhibitors of Viral Infectivity

Advanced Healthcare Materials
2021-03 | Journal article
DOI: 10.1002/adhm.202001433
Contributors: Alexander N. Zelikin; Francesco Stellacci
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Crossref

Nanozymes and Glucuronides: Glucuronidase, Esterase, and/or Transferase Activity

Small
2020-11 | Journal article
DOI: 10.1002/smll.202004280
Contributors: Raoul Walther; Wouter van den Akker; Anne Sofie Fruergaard; Alexander N. Zelikin
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Crossref

Chemical Artificial Internalizing Receptors for Primary T Cells

Advanced Science
2020-09 | Journal article
DOI: 10.1002/advs.202001395
Contributors: Pere Monge; Anne Tvilum; Ane Bretschneider Søgaard; Kaja Borup Løvschall; Morten T. Jarlstad Olesen; Alexander N. Zelikin
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Crossref

Molecular, Macromolecular, and Supramolecular Glucuronide Prodrugs: Lead Identified for Anticancer Prodrug Monotherapy

Angewandte Chemie International Edition
2020-05-04 | Journal article
DOI: 10.1002/anie.201916124
Contributors: Morten T. Jarlstad Olesen; Raoul Walther; Pier Paolo Poier; Frederik Dagnæs‐Hansen; Alexander N. Zelikin
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Crossref

Molecular, Macromolecular, and Supramolecular Glucuronide Prodrugs: Lead Identified for Anticancer Prodrug Monotherapy

Angewandte Chemie
2020-05-04 | Journal article
DOI: 10.1002/ange.201916124
Contributors: Morten T. Jarlstad Olesen; Raoul Walther; Pier Paolo Poier; Frederik Dagnæs‐Hansen; Alexander N. Zelikin
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Crossref

Extended scaffold glucuronides: en route to the universal synthesis of O-aryl glucuronide prodrugs

Organic & Biomolecular Chemistry
2019 | Journal article
DOI: 10.1039/C9OB01384A
Contributors: Raoul Walther; Morten T. Jarlstad Olesen; Alexander N. Zelikin
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Crossref

Unique enzymatic repertoire reveals the tumour.

Nature chemistry
2019-12 | Journal article
DOI: 10.1038/s41557-019-0400-0
PMID: 31836871
Contributors: Zelikin AN
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists.

Angewandte Chemie (International ed. in English)
2019-09 | Journal article
DOI: 10.1002/anie.201905687
PMID: 31397948
Contributors: De Vrieze J; Louage B; Deswarte K; Zhong Z; De Coen R; Van Herck S; Nuhn L; Kaas Frich C; Zelikin AN; Lienenklaus S et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Nucleic Acids as a Nature‐Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues

Advanced Science
2019-03 | Journal article
DOI: 10.1002/advs.201802095
Contributors: Franziska Krüger; Vipin Kumar; Pere Monge; Carina Conzelmann; Nikaïa Smith; Kurt V. Gothelf; Martin Tolstrup; Jan Münch; Alexander N. Zelikin
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Crossref

Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs.

Chemical communications (Cambridge, England)
2019-01 | Journal article
DOI: 10.1039/c8cc08737g
PMID: 30489589
Contributors: Ter Meer M; Dillion R; Nielsen SM; Walther R; Meyer RL; Daamen WF; van den Heuvel LP; van der Vliet JA; Lomme RMLM; Hoogeveen YL et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Antifouling properties of layer by layer DNA coatings

Biofouling
2019-01-02 | Journal article
DOI: 10.1080/08927014.2019.1568417
Contributors: Guruprakash Subbiahdoss; Guanghong Zeng; Hüsnü Aslan; Jakob Ege Friis; Joseph Iruthayaraj; Alexander N. Zelikin; Rikke Louise Meyer
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Crossref

Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs.

Journal of controlled release : official journal of the Controlled Release Society
2018-12 | Journal article
DOI: 10.1016/j.jconrel.2018.12.016
PMID: 30552954
Contributors: Frich CK; Krüger F; Walther R; Domar C; Andersen AHF; Tvilum A; Dagnæs-Hansen F; Denton PW; Tolstrup M; Paludan SR et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Identification and Directed Development of Non-Organic Catalysts with Apparent Pan-Enzymatic Mimicry into Nanozymes for Efficient Prodrug Conversion.

Angewandte Chemie (International ed. in English)
2018-11 | Journal article
DOI: 10.1002/anie.201812668
PMID: 30408323
Contributors: Walther R; Winther AK; Fruergaard AS; van den Akker W; Sørensen L; Nielsen SM; Jarlstad Olesen MT; Dai Y; Jeppesen HS; Lamagni P et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Combatting implant-associated biofilms through localized drug synthesis

Journal of Controlled Release
2018-10 | Journal article
DOI: 10.1016/j.jconrel.2018.08.025
Contributors: Raoul Walther; Signe Maria Nielsen; Rikke Christiansen; Rikke L. Meyer; Alexander N. Zelikin
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Crossref

Bi‐Enzymatic Embolization Beads for Two‐Armed Enzyme‐Prodrug Therapy

Advanced Therapeutics
2018-08 | Journal article
DOI: 10.1002/adtp.201800023
Contributors: Morten T. Jarlstad Olesen; Anna K. Winther; Betina Fejerskov; Frederik Dagnaes‐Hansen; Ulf Simonsen; Alexander N. Zelikin
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Crossref

Long-Acting, Potent Delivery of Combination Antiretroviral Therapy

ACS Macro Letters
2018-05-15 | Journal article
DOI: 10.1021/acsmacrolett.8b00179
Contributors: Anna H. F. Andersen; Camilla F. Riber; Kaja Zuwala; Martin Tolstrup; Frederik Dagnæs-Hansen; Paul W. Denton; Alexander N. Zelikin
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Crossref

Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects

Journal of Controlled Release
2018-04 | Journal article
DOI: 10.1016/j.jconrel.2018.02.012
Contributors: Kaja Zuwala; Camilla F. Riber; Kaja Borup Løvschall; Anna H.F. Andersen; Lise Sørensen; Paulina Gajda; Martin Tolstrup; Alexander N. Zelikin
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Crossref

Progress and Promise of Nitric Oxide-Releasing Platforms.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2018-04 | Journal article
DOI: 10.1002/advs.201701043
PMID: 29938181
PMC: PMC6010811
Contributors: Yang T; Zelikin AN; Chandrawati R
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Enzyme Prodrug Therapy Achieves Site-Specific, Personalized Physiological Responses to the Locally Produced Nitric Oxide.

ACS applied materials & interfaces
2018-03 | Journal article
DOI: 10.1021/acsami.8b01658
PMID: 29570264
PMC: PMC5887086
Contributors: Winther AK; Fejerskov B; Ter Meer M; Jensen NBS; Dillion R; Schaffer JE; Chandrawati R; Stevens MM; Schultze Kool LJ; Simonsen U et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection.

Antiviral research
2018-02 | Journal article
DOI: 10.1016/j.antiviral.2018.02.003
PMID: 29428508
Contributors: Röcker AE; Müller JA; Dietzel E; Harms M; Krüger F; Heid C; Sowislok A; Riber CF; Kupke A; Lippold S et al.
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Enzyme prodrug therapies and therapeutic enzymes.

Advanced drug delivery reviews
2017-09 | Journal article
DOI: 10.1016/j.addr.2017.10.006
PMID: 29054356
Contributors: Städler B; Zelikin AN
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses.

Advanced healthcare materials
2017-09 | Journal article
DOI: 10.1002/adhm.201700748
PMID: 28945945
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Preparation, Single-Molecule Manipulation, and Energy Transfer Investigation of a Polyfluorene-graft-DNA polymer.

Chemistry (Weinheim an Der Bergstrasse, Germany)
2017-08 | Journal article
DOI: 10.1002/chem.201702780
PMID: 28640936
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics.

Advanced healthcare materials
2017-07 | Journal article
DOI: 10.1002/adhm.201700385
PMID: 28699219
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Prodrugs in medicinal chemistry and enzyme prodrug therapies.

Advanced drug delivery reviews
2017-07 | Journal article
DOI: 10.1016/j.addr.2017.06.013
PMID: 28676386
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central
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Preferred source (of 2)‎

Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma.

Advanced materials (Deerfield Beach, Fla.)
2017-04 | Journal article
DOI: 10.1002/adma.201604932
PMID: 28221702
PMC: PMC5400071
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Substrate mediated enzyme prodrug therapy.

Advanced drug delivery reviews
2017-04 | Journal article
DOI: 10.1016/j.addr.2017.04.013
PMID: 28457884
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Macromolecular Prodrugs of Ribavirin: Structure-Function Correlation as Inhibitors of Influenza Infectivity.

Molecular pharmaceutics
2017-01 | Journal article
DOI: 10.1021/acs.molpharmaceut.6b00826
PMID: 28043136
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Materials and methods for delivery of biological drugs.

Nature chemistry
2016-10 | Journal article
DOI: 10.1038/nchem.2629
PMID: 27768097
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Poly(vinyl alcohol) Physical Hydrogels: Matrix-Mediated Drug Delivery Using Spontaneously Eroding Substrate.

The journal of physical chemistry. B
2016-07 | Journal article
DOI: 10.1021/acs.jpcb.6b01381
PMID: 26958864
PMC: PMC4939746
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1.

Molecular pharmaceutics
2016-07 | Journal article
DOI: 10.1021/acs.molpharmaceut.6b00156
PMID: 27244595
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central

Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity.

Advanced healthcare materials
2016-03 | Journal article
DOI: 10.1002/adhm.201500841
PMID: 26789641
Source: Self-asserted source
Alexander Zelikin via Europe PubMed Central
Items per page:
Page 1 of 3

Peer review (35 reviews for 20 publications/grants)

Review activity for ACS applied materials & interfaces. (3)
Review activity for ACS applied polymer materials. (2)
Review activity for ACS biomaterials science & engineering. (1)
Review activity for ACS chemical neuroscience. (1)
Review activity for ACS medicinal chemistry letters. (1)
Review activity for ACS nano. (1)
Review activity for ACS omega. (2)
Review activity for ACS sensors. (1)
Review activity for Advanced nanoBiomed research. (1)
Review activity for Angewandte Chemie. (1)
Review activity for Bioconjugate chemistry. (2)
Review activity for Biomacromolecules. (9)
Review activity for Chemical reviews. (1)
Review activity for Journal of medicinal chemistry. (1)
Review activity for Journal of the American Chemical Society. (3)
Review activity for Macromolecular rapid communications. (1)
Review activity for Macromolecules. (1)
Review activity for Molecular pharmaceutics. (1)
Review activity for Nano letters. (1)
Review activity for The journal of physical chemistry. (1)
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