Personal information

Activities

Employment (3)

Université Laval: Quebec, QC, CA

2020-11-15 to present | Postdoc (Department of psychiatry and neurosciences)
Employment
Source: Self-asserted source
Julia Obergasteiger

Institute for Biomedicine: Bolzano, IT

2019-11-04 to 2020-11-03 | Postdoctoral researcher (Eurac research)
Employment
Source: Self-asserted source
Julia Obergasteiger

Eurac research: Bolzano, IT

2016-06-01 to 2016-09-30 | Junior researcher (Institute for Biomedicine)
Employment
Source: Self-asserted source
Julia Obergasteiger

Education and qualifications (3)

University of Ferrara: Ferrara, IT

2016-10-01 to 2020-03-12 | PhD in Neuroscience
Education
Source: Self-asserted source
Julia Obergasteiger

University of Innsbruck: Innsbruck, AT

2013-11-01 to 2016-06-20 | Master of Science
Education
Source: Self-asserted source
Julia Obergasteiger

University Innsbruck: Innsbruck, AT

2010-10-01 to 2013-10-31 | Bachelor of Science in Biology
Education
Source: Self-asserted source
Julia Obergasteiger

Funding (1)

Neuroprotective function of Flcn KO in PD

2020-11 to 2022-10 | Salary award
Parkinson Canada (ON, ON, CA)
Source: Self-asserted source
Julia Obergasteiger

Works (7)

The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology

npj Parkinson's Disease
2023-03-27 | Journal article
Part of ISSN: 2373-8057
Contributors: Julia Obergasteiger; Anne-Marie Castonguay; Sara Pizzi; Stefano Magnabosco; Giulia Frapporti; Evy Lobbestael; Veerle Baekelandt; Andrew Hicks; Peter P Pramstaller; Claude Gravel et al.
Source: Self-asserted source
Julia Obergasteiger

Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions.

Cell death discovery
2020-06 | Journal article
Contributors: Obergasteiger J; Frapporti G; Lamonaca G; Pizzi S; Picard A; Lavdas AA; Pischedda F; Piccoli G; Hilfiker S; Lobbestael E et al.
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons.

Stem cell research
2019-11 | Journal article
Contributors: Überbacher C; Obergasteiger J; Volta M; Venezia S; Müller S; Pesce I; Pizzi S; Lamonaca G; Picard A; Cattelan G et al.
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics.

Molecular neurodegeneration
2018-08 | Journal article
Contributors: Obergasteiger J; Frapporti G; Pramstaller PP; Hicks AA; Volta M
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

Cryopreservation of Primary Mouse Neurons: The Benefit of Neurostore Cryoprotective Medium.

Frontiers in cellular neuroscience
2018-03 | Journal article
Contributors: Pischedda F; Montani C; Obergasteiger J; Frapporti G; Corti C; Rosato Siri M; Volta M; Piccoli G
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

CADPS2 gene expression is oppositely regulated by LRRK2 and alpha-synuclein.

Biochemical and biophysical research communications
2017-06 | Journal article
Contributors: Obergasteiger J; Überbacher C; Pramstaller PP; Hicks AA; Corti C; Volta M
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors.

Cellular signalling
2016-11 | Journal article
Contributors: Volta M; Lavdas AA; Obergasteiger J; Überbacher C; Picard A; Pramstaller PP; Hicks AA; Corti C
Source: Self-asserted source
Julia Obergasteiger via Europe PubMed Central

Peer review (5 reviews for 2 publications/grants)

Review activity for STAR protocols. (4)
Review activity for Translational neurodegeneration. (1)