Personal information

Activities

Employment (1)

Dalhousie University Faculty of Medicine: Halifax, NS, CA

2006-07-01 to present | Professor (Pharmacology and Surgery)
Employment
Source: Self-asserted source
Jim Fawcett

Education and qualifications (1)

McGill University Faculty of Medicine: Montreal, QC, CA

1997-09-01 to 1999-10-15 | PhD (Neurology and Neurosurgery)
Education
Source: Self-asserted source
Jim Fawcett

Works (42)

A large-scale, targeted metabolomics method for the analysis and quantification of metabolites in human plasma via liquid chromatography-mass spectrometry

Analytica Chimica Acta
2023-10 | Journal article
Contributors: Teresa S. McMillen; Andrew Leslie; Kenneth Chisholm; Susanne Penny; Jeffrey Gallant; Alejandro Cohen; Arik Drucker; James P. Fawcett; Devanand M. Pinto
Source: check_circle
Crossref

NCK1 Modulates Neuronal Actin Dynamics and Promotes Dendritic Spine, Synapse, and Memory Formation

The Journal of Neuroscience
2023-02-08 | Journal article
Contributors: Antonios M. Diab; Michael Wigerius; Dylan P. Quinn; Jiansong Qi; Ibrahim Shahin; Julia Paffile; Kavita Krueger; Barbara Karten; Stefan R. Krueger; James P. Fawcett
Source: check_circle
Crossref

NCK1 Regulates Amygdala Activity to Control Context-dependent Stress Responses and Anxiety in Male Mice

Neuroscience
2020 | Journal article
EID:

2-s2.0-85092105394

Part of ISSN: 18737544 03064522
Contributors: Diab, A.; Qi, J.; Shahin, I.; Milligan, C.; Fawcett, J.P.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Emerging roles for angiomotin in the nervous system

Science Signaling
2020-10-27 | Journal article
Contributors: Michael Wigerius; Dylan Quinn; James P. Fawcett
Source: check_circle
Crossref
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Preferred source (of 2)‎

The stability of glutamatergic synapses is independent of activity level, but predicted by synapse size

Frontiers in Cellular Neuroscience
2019 | Journal article
EID:

2-s2.0-85068444337

Part of ISSN: 16625102
Contributors: Quinn, D.P.; Kolar, A.; Harris, S.A.; Wigerius, M.; Fawcett, J.P.; Krueger, S.R.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis

eLife
2018 | Journal article
EID:

2-s2.0-85051840672

Part of ISSN: 2050084X
Contributors: Stairs, C.W.; Eme, L.; Muñoz-Gómez, S.A.; Cohen, A.; Dellaire, G.; Shepherd, J.N.; Fawcett, J.P.; Roger, A.J.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

The polarity protein Angiomotin p130 controls dendritic spine maturation

Journal of Cell Biology
2018-02-05 | Journal article
Contributors: Michael Wigerius; Dylan Quinn; Antonios Diab; Leanne Clattenburg; Annette Kolar; Jiansong Qi; Stefan R. Krueger; James P. Fawcett
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Crossref
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Preferred source (of 2)‎

Analysis of 17β-estradiol, estriol and estrone in American eel (Anguilla rostrata) tissue samples using liquid chromatography coupled to electrospray differential ion mobility tandem mass spectrometry

Rapid Communications in Mass Spectrometry
2017 | Journal article
EID:

2-s2.0-85018493303

Part of ISSN: 10970231 09514198
Contributors: Cohen, A.; Ross, N.W.; Smith, P.M.; Fawcett, J.P.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85013304699

Part of ISSN: 20452322
Contributors: Quinn, D.P.; Kolar, A.; Wigerius, M.; Gomm-Kolisko, R.N.; Atwi, H.; Fawcett, J.P.; Krueger, S.R.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma

Journal of Otolaryngology - Head and Neck Surgery
2017 | Journal article
EID:

2-s2.0-85013229419

Part of ISSN: 19160216
Contributors: Alzahrani, F.; Clattenburg, L.; Muruganandan, S.; Bullock, M.; MacIsaac, K.; Wigerius, M.; Williams, B.A.; Graham, M.E.R.; Rigby, M.H.; Trites, J.R.B. et al.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism

Molecular and Cellular Endocrinology
2016 | Journal article
EID:

2-s2.0-84979787256

Part of ISSN: 18728057 03037207
Contributors: Dranse, H.J.; Muruganandan, S.; Fawcett, J.P.; Sinal, C.J.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Determination of Flow Rates in Capillary Liquid Chromatography Coupled to a Nanoelectrospray Source using Droplet Image Analysis Software

Analytical Chemistry
2016 | Journal article
EID:

2-s2.0-84982706258

Part of ISSN: 15206882 00032700
Contributors: Cohen, A.M.; Soto, A.J.; Fawcett, J.P.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Motoneurons derived from induced pluripotent stem cells develop mature phenotypes typical of endogenous spinal motoneurons

Journal of Neuroscience
2015 | Journal article
EID:

2-s2.0-84921473271

Part of ISSN: 15292401 02706474
Contributors: Toma, J.S.; Shettar, B.C.; Chipman, P.H.; Pinto, D.M.; Borowska, J.P.; Ichida, J.K.; Fawcett, J.P.; Zhang, Y.; Eggan, K.; Rafuse, V.F.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

NCK is critical for the development of deleted in colorectal cancer (DCC) sensitive spinal circuits

Journal of Neurochemistry
2015 | Journal article
EID:

2-s2.0-84941742885

Part of ISSN: 14714159 00223042
Contributors: Lane, C.; Qi, J.; Fawcett, J.P.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

NOS1AP functionally associates with YAP to regulate hippo signaling

Molecular and Cellular Biology
2015 | Journal article
EID:

2-s2.0-84930858091

Part of ISSN: 10985549 02707306
Contributors: Clattenburg, L.; Wigerius, M.; Qi, J.; Rainey, J.K.; Rourke, J.L.; Muruganandan, S.; Sinal, C.J.; Fawcett, J.P.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Sim1 is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord

Developmental Neurobiology
2015 | Journal article
EID:

2-s2.0-84938992492

Part of ISSN: 1932846X 19328451
Contributors: Blacklaws, J.; Deska-Gauthier, D.; Jones, C.T.; Petracca, Y.L.; Liu, M.; Zhang, H.; Fawcett, J.P.; Glover, J.C.; Lanuza, G.M.; Zhang, Y.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration

Oncotarget
2015 | Journal article
EID:

2-s2.0-84929649412

Part of ISSN: 19492553
Contributors: Kai, F.; Fawcett, J.P.; Duncan, R.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Increases in mature brain-derived neurotrophic factor protein in the frontal cortex and basal forebrain during chronic sleep restriction in rats: Possible role in initiating allostatic adaptation

Neuroscience
2014 | Journal article
EID:

2-s2.0-84904862459

Part of ISSN: 18737544 03064522
Contributors: Wallingford, J.K.; Deurveilher, S.; Currie, R.W.; Fawcett, J.P.; Semba, K.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Guidance of postural motoneurons requires MAPK/ERK signaling downstream of fibroblast growth factor receptor 1

Journal of Neuroscience
2010 | Journal article
EID:

2-s2.0-77952349952

Part of ISSN: 02706474 15292401
Contributors: Soundararajan, P.; Fawcett, J.P.; Rafuse, V.F.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

NOS1AP associates with scribble and regulates dendritic spine development

Journal of Neuroscience
2010 | Journal article
EID:

2-s2.0-77950680767

Part of ISSN: 02706474 15292401
Contributors: Richier, L.; Williton, K.; Clattenburg, L.; Colwill, K.; O'Brien, M.; Tsang, C.; Kolar, A.; Zinck, N.; Metalnikov, P.; Trimble, W.S. et al.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Par3 and Dynein Associate to Regulate Local Microtubule Dynamics and Centrosome Orientation during Migration

Current Biology
2009 | Journal article
EID:

2-s2.0-67649859266

Part of ISSN: 09609822
Contributors: Schmoranzer, J.; Fawcett, J.P.; Segura, M.; Tan, S.; Vallee, R.B.; Pawson, T.; Gundersen, G.G.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Multiple KCNQ potassium channel subtypes mediate basal anion secretion from the human airway epithelial cell line Calu-3

Journal of Membrane Biology
2008 | Journal article
EID:

2-s2.0-40549096341

Part of ISSN: 00222631
Contributors: Moser, S.L.; Harron, S.A.; Crack, J.; Fawcett, J.P.; Cowley, E.A.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Combinatorial ShcA docking interactions support diversity in tissue morphogenesis

Science
2007 | Journal article
EID:

2-s2.0-34447513028

Part of ISSN: 00368075 10959203
Contributors: Hardy, W.R.; Li, L.; Wang, Z.; Sedy, J.; Fawcett, J.; Frank, E.; Kucera, J.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Nck adaptor proteins control the organization of neuronal circuits important for walking

Proceedings of the National Academy of Sciences of the United States of America
2007 | Journal article
EID:

2-s2.0-38049173095

Part of ISSN: 00278424 10916490
Contributors: Fawcett, J.P.; Georgiou, J.; Ruston, J.; Bladt, F.; Sherman, A.; Warner, N.; Saab, B.J.; Scott, R.; Roder, J.C.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

A Rich1/Amot Complex Regulates the Cdc42 GTPase and Apical-Polarity Proteins in Epithelial Cells

Cell
2006 | Journal article
EID:

2-s2.0-33646136870

Part of ISSN: 00928674
Contributors: Wells, C.D.; Fawcett, J.P.; Traweger, A.; Yamanaka, Y.; Goudreault, M.; Elder, K.; Kulkarni, S.; Gish, G.; Virag, C.; Lim, C. et al.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control

Nature Cell Biology
2006 | Journal article
EID:

2-s2.0-33750505436

Part of ISSN: 14657392
Contributors: Aranda, V.; Haire, T.; Nolan, M.E.; Calarco, J.P.; Rosenberg, A.Z.; Fawcett, J.P.; Pawson, T.; Muthuswamy, S.K.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

The polarity protein Par-3 directly interacts with p75 <sup>NTR</sup> to regulate myelination

Science
2006 | Journal article
EID:

2-s2.0-33750681355

Part of ISSN: 00368075 10959203
Contributors: Chan, J.R.; Jolicoeur, C.; Yamauchi, J.; Elliott, J.; Fawcett, J.P.; Ng, B.K.; Cayouette, M.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Polarity proteins in axon specification and synaptogenesis

Developmental Cell
2005 | Journal article
EID:

2-s2.0-19944381540

Part of ISSN: 15345807
Contributors: Wiggin, G.R.; Fawcett, J.P.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

Current Biology
2004 | Journal article
EID:

2-s2.0-4344598183

Part of ISSN: 09609822
Contributors: Jin, J.; Smith, F.D.; Stark, C.; Wells, C.D.; Fawcett, J.P.; Kulkarni, S.; Metalnikov, P.; O'Donnell, P.; Taylor, P.; Taylor, L. et al.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

Nature Cell Biology
2003 | Journal article
EID:

2-s2.0-0037385561

Part of ISSN: 14657392
Contributors: Plant, P.J.; Fawcett, J.P.; Lin, D.C.C.; Holdorf, A.D.; Binns, K.; Kulkarni, S.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

Nature Cell Biology
2000 | Journal article
EID:

2-s2.0-0000202186

Part of ISSN: 14657392
Contributors: Lin, D.; Edwards, A.S.; Fawcett, J.P.; Mbamalu, G.; Scott, J.D.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Evidence that brain-derived neurotrophic factor from presynaptic nerve terminals regulates the phenotype of calbindin-containing neurons in the lateral septum

Journal of Neuroscience
2000 | Journal article
EID:

2-s2.0-0033995149

Part of ISSN: 02706474
Contributors: Fawcett, J.P.; Alonso-Vanegas, M.A.; Morris, S.J.; Miller, F.D.; Sadikot, A.F.; Murphy, R.A.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Signal transduction: N-WASP regulation - The sting in the tail

Science
2000 | Journal article
EID:

2-s2.0-0034721695

Part of ISSN: 00368075
Contributors: Fawcett, J.; Pawson, T.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS

Learning and Memory
1999 | Journal article
EID:

2-s2.0-0032876611

Part of ISSN: 10720502
Contributors: Aloyz, R.; Fawcett, J.P.; Kaplan, D.R.; Murphy, R.A.; Miller, F.D.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Characterization of dopaminergic midbrain neurons in a DBH:BDNF transgenic mouse

Journal of Comparative Neurology
1999 | Journal article
EID:

2-s2.0-0033604316

Part of ISSN: 00219967
Contributors: Alonso-Vanegas, M.A.; Fawcett, J.P.; Causing, C.G.; Miller, F.D.; Sadikot, A.F.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons

Journal of Neuroscience
1999 | Journal article
EID:

2-s2.0-0033559386

Part of ISSN: 02706474
Contributors: Mowla, S.J.; Pareek, S.; Farhadi, H.F.; Petrecca, K.; Fawcett, J.P.; Seidah, N.G.; Morris, S.J.; Sossin, W.S.; Murphy, R.A.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Functional evidence that BDNF is an anterograde neuronal trophic factor in the CNS

Journal of Neuroscience
1998 | Journal article
EID:

2-s2.0-0032523124

Part of ISSN: 02706474
Contributors: Fawcett, J.P.; Bamji, S.X.; Causing, C.G.; Aloyz, R.; Ase, A.R.; Reader, T.A.; McLean, J.H.; Miller, F.D.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes

Journal of Biological Chemistry
1997 | Journal article
EID:

2-s2.0-0031002892

Part of ISSN: 00219258
Contributors: Fawcett, J.P.; Aloyz, R.; McLean, J.H.; Pareek, S.; Miller, F.D.; McPherson, P.S.; Murphy, R.A.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Synaptic innervation density is regulated by neuron-derived BDNF

Neuron
1997 | Journal article
EID:

2-s2.0-0031039772

Part of ISSN: 08966273
Contributors: Causing, C.G.; Gloster, A.; Aloyz, R.; Bamji, S.X.; Chang, E.; Fawcett, J.; Kuchel, G.; Miller, F.D.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis

Journal of Neuroscience
1997 | Journal article
EID:

2-s2.0-16944367478

Part of ISSN: 02706474
Contributors: Majdan, M.; Lachance, C.; Gloster, A.; Aloyz, R.; Zeindler, C.; Bamji, S.; Bhakar, A.; Belliveau, D.; Fawcett, J.; Miller, F.D. et al.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

The role of NGF in the peripheral nervous system

Restorative Neurology and Neuroscience
1995 | Journal article
EID:

2-s2.0-0029076379

Part of ISSN: 18783627 09226028
Contributors: Diamond, J.; Lourenssen, S.; Kril, Y.; Fawcett, J.; Gloster, A.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier

Antibody to NGF inhibits collateral sprouting of septohippocampal fibers following entorhinal cortex lesion in adult rats

Journal of Comparative Neurology
1992 | Journal article
EID:

2-s2.0-0026469380

Part of ISSN: 10969861 00219967
Contributors: Van Der Zee, C.E.E.M.; Fawcett, J.; Diamond, J.
Source: Self-asserted source
Jim Fawcett via Scopus - Elsevier