Personal information

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Other IDs

Scopus Author ID: 57203090796
ResearcherID: AAG-3098-2021

Keywords

Genetic diseases, Pharmacogenetics, Pharmacology, Pain Medicine

Countries

Spain

Activities

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Employment (3)

Instituto de Investigación Sanitaria y Biomédica de Alicante: Alicante, Comunidad Valenciana, ES

Investigador postdoctoral (Medicina Interna, Enfermedades Genéticas)
Employment
Source: Self-asserted source
Javier Muriel

Instituto de investigación sanitaria y biomédica de Alicante: Alicante, Comunidad Valenciana, ES

2022-11 to present | Subcoordinador (Plataforma de Farmacogenética aplicada a la Investigación)
Employment
Source: Self-asserted source
Javier Muriel

Universidad Miguel Hernández de Elche: Elche, Valenciana, ES

2021-10-01 to present | Profesor Asociado (Farmacología Clínica)
Employment
Source: Self-asserted source
Javier Muriel

Education and qualifications (3)

Universidad Miguel Hernández de Elche: Elche, Valenciana, ES

2019-07 | PhD in Bioengineering
Education
Source: Self-asserted source
Javier Muriel

Universidad Miguel Hernández de Elche: Elche, Valenciana, ES

2016-07 | Msc in Biotechnology and Bioengineering
Education
Source: Self-asserted source
Javier Muriel

Universidad de Salamanca: Salamanca, Castilla y León, ES

2011-09 | Graduate in Pharmacy
Education
Source: Self-asserted source
Javier Muriel

Professional activities (4)

Real Academia Nacional de Doctores: Madrid, ES

2020-11 | Premio Juan Abelló Pascual (ex aequo)
Distinction
Source: Self-asserted source
Javier Muriel

Fundación Española del Dolor: Madrid, ES

2020-06 | Premio mejor Tesis Doctoral de Dolor 2020
Distinction
Source: Self-asserted source
Javier Muriel

Fundación Grünenthal España: Madrid, Comunidad de Madrid, ES

2018-12 | Premio a la Investigación en Dolor 2018 en la categoría de Investigación Clínica
Distinction
Source: Self-asserted source
Javier Muriel

Real Academia Nacional de Farmacia: Madrid, Comunidad de Madrid, ES

2018-01 | Premio Alcaliber-Iberoamérica
Distinction
Source: Self-asserted source
Javier Muriel

Works (38)

Status of the implementation of pharmacogenetics in clinical practice in Spain: from regional to national initiatives

Drug Metabolism and Personalized Therapy
2024-11-11 | Journal article
DOI: 10.1515/dmpt-2024-0042
Part of ISSN: 2363-8915
Contributors: Maria Apellaniz-Ruiz; Jordi Barrachina; Paula Castro-Sanchez; Ana Comes-Raga; Xandra García-González; Almudena Gil-Rodriguez; Elixabet Lopez-Lopez; Olalla Maroñas; Rocío Morón; Javier Muriel et al.
Source: Self-asserted source
Javier Muriel

Predictive Model for Opioid Use Disorder in Chronic Pain: A Development and Validation Study

Biomedicines
2024-09-10 | Journal article
DOI: 10.3390/biomedicines12092056
Contributors: Mónica Escorial; Javier Muriel; César Margarit; Laura Agulló; Thomas Zandonai; Ana Panadero; Domingo Morales; Ana M. Peiró
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Association of Human Leukocyte Antigen Alleles with COVID-19 Severity and Mortality in a Spanish Population

Medicina
2024-08-25 | Journal article
DOI: 10.3390/medicina60091392
Contributors: Ester Lobato-Martinez; Javier Muriel-Serrano; Elena García-Payá; Pilar Gonzalez-de-la-Aleja; Raquel Garcia-Sevila; Mercedes Navarro-de-Miguel; Francisco Marco-de-la-Calle; Jose-Manuel Ramos-Rincon; Rosario Sanchez-Martinez
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Epigenetic and sex differences in opioid use disorder in chronic pain: A real‐world study linked with <i>OPRM1</i> DNA methylation

Addiction Biology
2024-07 | Journal article
DOI: 10.1111/adb.13422
Part of ISSN: 1355-6215
Part of ISSN: 1369-1600
Contributors: Laura Agulló; Mónica Escorial; Samantha Orutño; Javier Muriel; Juan Sandoval; César Margarit; Ana Peiro
Source: Self-asserted source
Javier Muriel

Erectile dysfunction in cardiovascular patients: A prospective study of the <i>eNOS</i> gene T‐786C, G894T, and INTRON variable number of the tandem repeat functional interaction

Andrology
2024-07 | Journal article
DOI: 10.1111/andr.13671
Part of ISSN: 2047-2919
Part of ISSN: 2047-2927
Contributors: Ana Segura; Javier Muriel; Pau Miró; Laura Agulló; Vicente Arrarte; Patricia Carracedo; Thomas Zandonai; Ana M Peiró
Source: Self-asserted source
Javier Muriel

Use of CYP2D6 substrates and inhibitors during pain management with analgesic opioids: Drug-drug interactions that lead to lack of analgesic effectiveness

Biomedicine &amp; Pharmacotherapy
2024-07 | Journal article
DOI: 10.1016/j.biopha.2024.116882
Part of ISSN: 0753-3322
Contributors: J. Muriel; M. Escorial; C. Carratalá; C. Margarit; J. Barrachina; A. López; E. Gallardo; MK Kringen; A.M. Peiró
Source: Self-asserted source
Javier Muriel

Clinical prediction of opioid use disorder in chronic pain patients: a cohort-retrospective study with a pharmacogenetic approach

Minerva Anestesiologica
2024-05 | Journal article
DOI: 10.23736/s0375-9393.24.17864-9
Part of ISSN: 0375-9393
Part of ISSN: 1827-1596
Contributors: Mónica ESCORIAL; Javier MURIEL; Laura AGULLÓ; Thomas ZANDONAI; César MARGARIT; Domingo MORALES; Ana M. PEIRÓ
Source: Self-asserted source
Javier Muriel

Farmacogenética y respuesta analgésica: hacia una medicina personalizada con análisis de las diferencias por sexo

Revista de la Sociedad Española del Dolor
2023 | Journal article
DOI: 10.20986/resed.2023.4042/2022
Part of ISSN: 1134-8046
Contributors: Beatriz Orts Jorquera; Javier Muriel Serrano; Ana María Peiró Peiró
Source: Self-asserted source
Javier Muriel

CYP2D6 Genotype and Pharmacovigilance Impact on Autism Spectrum Disorder: A Naturalistic Study with Extreme Phenotype Analysis

Pharmaceuticals
2023-07-03 | Journal article
DOI: 10.3390/ph16070954
Part of ISSN: 1424-8247
Contributors: Pura Ballester; Cristina Espadas; Susana Almenara; Jordi Barrachina; Javier Muriel; Enrique Ramos; Natalia Toral; César Belda; Ana Peiro
Source: Self-asserted source
Javier Muriel

Pharmacogenetic Guided Opioid Therapy Improves Chronic Pain Outcomes and Comorbid Mental Health: A Randomized, Double-Blind, Controlled Study

International Journal of Molecular Sciences
2023-06 | Journal article | Author
DOI: 10.3390/ijms241310754
Contributors: Laura Agulló; Isidro Aguado; Javier Muriel; César Margarit; Alba Gómez; Mónica Escorial; Astrid Sánchez; Alicia Fernández; Ana Peiro
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Long-term deprescription in chronic pain and opioid use disorder patients: Pharmacogenetic and sex differences

Acta Pharmaceutica
2023-06-01 | Journal article | Author
DOI: 10.2478/acph-2023-0018
Part of ISSN: 1846-9558
Contributors: Javier Muriel; Mónica Escorial; Cesar Margarit-Ferri; Jordi Barrachina; Cristian Carvajal; Domingo Morales; Ana Peiro
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Impact of CYP2D6 genotype on opioid use disorder deprescription: an observational prospective study in chronic pain with sex-differences

Frontiers in Pharmacology
2023-05-31 | Journal article
DOI: 10.3389/fphar.2023.1200430
Part of ISSN: 1663-9812
Contributors: Javier Muriel; Jordi Barrachina; Guillermo Del Barco; Cristian Carvajal; Mónica Escorial; César Margarit; Pura Ballester; Ana María Peiró
Source: Self-asserted source
Javier Muriel

Sex Differences in Opioid Response Linked to OPRM1 and COMT genes DNA Methylation/Genotypes Changes in Patients with Chronic Pain

Journal of Clinical Medicine
2023-05-13 | Journal article
DOI: 10.3390/jcm12103449
Part of ISSN: 2077-0383
Contributors: Laura Agulló; Javier Muriel; César Margarit; Mónica Escorial; Diana Garcia; Maria Jose Herrero; David Hervas; Juan Sandoval; Ana Peiro
Source: Self-asserted source
Javier Muriel

Oxycodone/naloxone versus tapentadol in real-world chronic non-cancer pain management: an observational and pharmacogenetic study

Scientific Reports
2022-12 | Journal article
DOI: 10.1038/s41598-022-13085-5
Part of ISSN: 2045-2322
Contributors: Javier Muriel
Source: Self-asserted source
Javier Muriel

Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study

Acta Pharmaceutica
2022-12-01 | Journal article | Author
DOI: 10.2478/acph-2022-0035
Part of ISSN: 1846-9558
Contributors: Jordi Barrachina; Cesar Margarit-Ferri; Blanca Andreu Ivorra; Thomas Zandonai; Pura Ballester; Javier Muriel; Esperanza Cutillas; Ana Peiro
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Intestinal microbiota is modified in pediatric food protein–induced enterocolitis syndrome

Journal of Allergy and Clinical Immunology: Global
2022-11 | Journal article | Author
DOI: 10.1016/j.jacig.2022.07.005
Part of ISSN: 2772-8293
Contributors: Esther Caparrós; María Carmen Cenit; Javier Muriel; Alfonso Benítez-Páez; María Victoria Moreno; Purificación González-Delgado; Gonzalo Rubio; Yolanda Sanz; Javier Fernández
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Sex Differences in Oxycodone/Naloxone vs. Tapentadol in Chronic Non-Cancer Pain: An Observational Real-World Study

Biomedicines
2022-10 | Journal article | Author
DOI: 10.3390/biomedicines10102468
Contributors: Jordi Barrachina; Cesar Margarit; Javier Muriel; Vicente López Gil; Santiago López Gil; Pura Ballester; Laura Mira-Lorente; Laura Agulló; Ana Peiro
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Sex-Differences in Pain and Opioid Use Disorder Management: A Cross-Sectional Real-World Study

Biomedicines
2022-09 | Journal article | Author
DOI: 10.3390/biomedicines10092302
Contributors: Mónica Escorial; Javier Muriel; César Margarit; Laura Agulló; Domingo Morales; Ana M. Peiró Peiró
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Food Protein–Induced Enterocolitis Syndrome in Adulthood: Clinical Characteristics, Prognosis, and Risk Factors

The Journal of Allergy and Clinical Immunology: In Practice
2022-05 | Journal article
DOI: 10.1016/j.jaip.2022.05.006
Part of ISSN: 2213-2198
Contributors: Javier Muriel
Source: Self-asserted source
Javier Muriel

CYP2D6 phenotypes and opioid metabolism: the path to personalized analgesia

Expert Opinion on Drug Metabolism &amp; Toxicology
2022-04-03 | Journal article
DOI: 10.1080/17425255.2022.2085552
Part of ISSN: 1742-5255
Part of ISSN: 1744-7607
Contributors: Javier Muriel
Source: Self-asserted source
Javier Muriel

The challenge of detecting adverse events in adults with autism spectrum disorder who have intellectual disability

Autism Research
2022-01 | Journal article
DOI: 10.1002/aur.2624
Part of ISSN: 1939-3792
Part of ISSN: 1939-3806
Source: Self-asserted source
Javier Muriel

Global Pain State Questionnaire: Reliability, Validity, and Gender Gap

Archives of Internal Medicine Research
2021 | Journal article
DOI: 10.26502/aimr.0061
Part of ISSN: 2688-5654
Source: Self-asserted source
Javier Muriel

Interplay of circadian clock and melatonin pathway gene variants in adults with autism, intellectual disability and sleep problems

Research in Autism Spectrum Disorders
2021 | Journal article
DOI: 10.1016/j.rasd.2020.101715
EID:

2-s2.0-85098543175

Part of ISSN: 18780237 17509467
Contributors: Ballester-Navarro, P.; Martínez-Madrid, M.J.; Javaloyes-Sanchís, A.; Belda-Cantó, C.; Aguilar, V.; Inda, M.-D.-M.; Richdale, A.L.; Muriel, J.; Morales, D.; Peiró, A.M.
Source: Self-asserted source
Javier Muriel via Scopus - Elsevier

Fluorescent in situ hybridization (FISH): A useful diagnostic tool for childhood conjunctival melanoma

European Journal of Ophthalmology
2021-07-09 | Journal article
DOI: 10.1177/11206721211030775
Part of ISSN: 1120-6721
Part of ISSN: 1724-6016
Source: Self-asserted source
Javier Muriel

Erectile dysfunction in patients with cardiovascular disease and the potential influence of genetic markers,Disfunción eréctil en pacientes con enfermedad cardiovascular y potencial influencia de marcadores genéticos

Revista Internacional de Andrologia
2020 | Journal article
DOI: 10.1016/j.androl.2020.03.001
EID:

2-s2.0-85088945596

Part of ISSN: 16980409 1698031X
Contributors: Ors, D.; Segura, A.; Arrarte, V.; Ballester, P.; Muriel, J.; Fernández, G.; Soriano, J.; Peiró, A.M.
Source: Self-asserted source
Javier Muriel via Scopus - Elsevier

Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects

Clinical Drug Investigation
2020-07 | Journal article
DOI: 10.1007/s40261-020-00921-7
Part of ISSN: 1173-2563
Part of ISSN: 1179-1918
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 3)‎

Sex Bias and Genotype Influence on Opioid Safety Profile in Chronic Low Back Pain

The Clinical Journal of Pain
2020-06 | Journal article
DOI: 10.1097/ajp.0000000000000824
Part of ISSN: 0749-8047
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Presurgical risk model for chronic postsurgical pain based on six clinical predictors

Pain
2020-06-05 | Journal article
DOI: 10.1097/j.pain.0000000000001945
Part of ISSN: 0304-3959
Source: Self-asserted source
Javier Muriel

Personality and psychiatric disorders in chronic pain male affected by erectile dysfunction: prospective and observational study

International Journal of Impotence Research
2020-05-07 | Journal article
DOI: 10.1038/s41443-020-0294-9
Part of ISSN: 0955-9930
Part of ISSN: 1476-5489
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Endothelial nitric oxide synthase gene polymorphisms and erectile dysfunction in chronic pain

Gene: X
2019 | Journal article
DOI: 10.1016/j.gene.2019.100005
EID:

2-s2.0-85061100422

Part of ISSN: 25901583
Contributors: Segura, A.; Ballester, P.; Ajo, R.; Inda, M.-D.-M.; Urbano, A.; Muriel, J.; Ochando, I.; Margarit, C.; Martinez, E.; Peiró, A.M.
Source: Self-asserted source
Javier Muriel via Scopus - Elsevier

Gender based differences, pharmacogenetics and adverse events in chronic pain management.

The pharmacogenomics journal
2019-11-20 | Journal article
DOI: 10.1038/s41397-019-0118-9
PMID: 31745220
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Genetic Contribution in Low Back Pain: A Prospective Genetic Association Study.

Pain practice : the official journal of World Institute of Pain
2019-09-03 | Journal article
DOI: 10.1111/papr.12816
PMID: 31269327
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Evaluation of agomelatine for the treatment of sleep problems in adults with autism spectrum disorder and co-morbid intellectual disability.

Journal of psychopharmacology (Oxford, England)
2019-08-19 | Journal article
DOI: 10.1177/0269881119864968
PMID: 31423939
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Effectiveness and pharmacogenetics in a deprescription protocol in chronic pain patients and iatrogenic opioid dependence,Efectividad y farmacogenética en un protocolo de desprescripción en pacientes con dolor crónico y dependencia iatrogénica a opioides

Anales de la Real Academia Nacional de Farmacia
2018 | Journal article
EID:

2-s2.0-85050498189

Part of ISSN: 1697428X
Contributors: Muriel, J.; Margarit, C.; Flor, A.; Morales, D.; Peiró, A.
Source: Self-asserted source
Javier Muriel via Scopus - Elsevier

Pharmacogenetics and prediction of adverse events in prescription opioid use disorder patients.

Basic & clinical pharmacology & toxicology
2018-12-13 | Journal article
DOI: 10.1111/bcpt.13155
PMID: 30549211
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Health benefits of an adverse events reporting system for chronic pain patients using long-term opioids.

Acta anaesthesiologica Scandinavica
2018-08-14 | Journal article
DOI: 10.1111/aas.13243
PMID: 30109708
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

OPRM1 influence on and effectiveness of an individualized treatment plan for prescription opioid use disorder patients.

Annals of the New York Academy of Sciences
2018-05-20 | Journal article
DOI: 10.1111/nyas.13735
PMID: 29781244
Source: Self-asserted source
Javier Muriel
grade
Preferred source (of 2)‎

Enfermedad de Marfan y Síndromes relacionados

Enfermedades Minoritarias en el Adulto
Book chapter
Contributors: Javier Muriel; Rosario Sánchez
Source: Self-asserted source
Javier Muriel
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