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Keywords

epithelium, cell polarity, intestine, stem cell

Countries

United Kingdom, Hong Kong SAR China, China

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Employment (4)

Gurdon Institute: Cambridge, Cambridgeshire, GB

2015-03 to present | Wellcome Research Associate
Employment
Source: Self-asserted source
Jia Chen

Gurdon Institute: Cambridge, Cambridgeshire, GB

2013-03 to 2015-02 | Royal Society KC Wong Research Fellow
Employment
Source: Self-asserted source
Jia Chen

Hong Kong University of Science and Technology: Kowloon, HK

2011-12 to 2012-11 | Research Associate (Biochemistry)
Employment
Source: Self-asserted source
Jia Chen

Hong Kong University of Science and Technology: Kowloon, HK

2005-02 to 2006-08 | Research Assistant (Biochemistry)
Employment
Source: Self-asserted source
Jia Chen

Education and qualifications (3)

Hong Kong University of Science and Technology: Kowloon, Hong Kong, HK

2006-09 to 2011-11 | Ph.D. (Biochemistry)
Education
Source: Self-asserted source
Jia Chen

University of Hong Kong: Hong Kong, HK

2002-09 to 2004-10 | M.Phil (Institute of Molecular Biology)
Education
Source: Self-asserted source
Jia Chen

Nankai University: Tianjin, Tianjin, CN

1998-09 to 2002-09 | B.Sc. (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Jia Chen

Funding (1)

Using Drosophila Gut as a model to study the development of intestine epithelial cell polarity

2013-03 to 2015-02 | Award
Royal Society (Manchester, GB)
Source: Self-asserted source
Jia Chen

Works (18)

Apical-basal polarity in the gut.

Seminars in cell & developmental biology
2023-01-18 | Journal article
DOI: 10.1016/j.semcdb.2022.12.007
PMID: 36670034
Contributors: Thottacherry JJ; Chen J; Johnston DS
Source: Self-asserted source
Jia Chen

Dissection, Fixation, and Immunostaining of the Drosophila Midgut

Cell Polarity Signaling: Methods and Protocols
2022 | Book chapter
Part of ISSN: 1064-3745
Source: Self-asserted source
Jia Chen

De novo apical domain formation inside the Drosophila adult midgut epithelium

eLife
2022-09-28 | Journal article | Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing - original draft, Writing - review & editing
DOI: 10.7554/eLife.76366
Contributors: Jia Chen; Daniel St Johnston
Source: Self-asserted source
Jia Chen
grade
Preferred source (of 2)‎

Epithelial Cell Polarity During Drosophila Midgut Development

Frontiers in Cell and Developmental Biology
2022-06-30 | Review
DOI: 10.3389/fcell.2022.886773
Part of ISSN: 2296-634X
Contributors: Jia Chen
Source: Self-asserted source
Jia Chen

De novo apical domain formation inside the Drosophila adult midgut epithelium

2021-12-11 | Preprint
DOI: 10.1101/2021.12.10.472136
Contributors: Jia Chen; Daniel St Johnston
Source: check_circle
Crossref

An alternative mode of epithelial polarity in the Drosophila midgut.

PLoS biology
2018-10-19 | Journal article
DOI: 10.1371/journal.pbio.3000041
PMID: 30339698
PMC: PMC6209374
Source: Self-asserted source
Jia Chen
grade
Preferred source (of 2)‎

An alternative mode of epithelial polarity in the Drosophila midgut

2018-04-24 | Other
DOI: 10.1101/307579
Contributors: Jia Chen; Aram-Christopher Sayadian; Nick Lowe; Holly E. Lovegrove; Daniel St Johnston
Source: check_circle
Crossref

Unexpected Heterodivalent Recruitment of NOS1AP to nNOS Reveals Multiple Sites for Pharmacological Intervention in Neuronal Disease Models.

2015-05-13 | Journal article
DOI: 10.1523/JNEUROSCI.0037-15.2015
Source: Self-asserted source
Jia Chen

Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl.

2014-04 | Journal article
DOI: 10.1038/cr.2014.16
Source: Self-asserted source
Jia Chen

Structural Insights into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain

2013-06 | Journal article
DOI: 10.1016/j.str.2013.04.004
Source: Self-asserted source
Jia Chen

The Par3/Par6/aPKC complex and epithelial cell polarity.

2013-06-10 | Journal article
DOI: 10.1016/j.yexcr.2013.03.021
Source: Self-asserted source
Jia Chen

Regulation of Microtubule Stability and Organization by Mammalian Par3 in Specifying Neuronal Polarity

2013-01-14 | Journal article
DOI: 10.1016/j.devcel.2012.11.014
Source: Self-asserted source
Jia Chen

The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Protein Suggests a Supramodular Organization of the Membrane-associated Guanylate Kinase (MAGUK) Family Scaffold Protein Core

2011-11-18 | Journal article
DOI: 10.1074/jbc.C111.293084
Source: Self-asserted source
Jia Chen

Extensions of PDZ domains as important structural and functional elements

2010-08 | Journal article
DOI: 10.1007/s13238-010-0099-6
Source: Self-asserted source
Jia Chen

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

2008-08-06 | Journal article
DOI: 10.1038/emboj.2008.138
Source: Self-asserted source
Jia Chen

PDZ Domains of Par-3 as Potential Phosphoinositide Signaling Integrators

2007-12-14 | Journal article
DOI: 10.1016/j.molcel.2007.10.028
Source: Self-asserted source
Jia Chen

Proteomics of buccal squamous cell carcinoma: The involvement of multiple pathways in tumorigenesis

2004-08 | Journal article
DOI: 10.1002/pmic.200300762
Source: Self-asserted source
Jia Chen

Identification of tumor-associated proteins in oral tongue squamous cell carcinoma by proteomics

2004-01 | Journal article
DOI: 10.1002/pmic.200300550
Source: Self-asserted source
Jia Chen
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