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Works (33)

VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities

mBio
2023-10-31 | Journal article
Contributors: Taylor M. Gerson; Audrey M. Ott; Monika M. A. Karney; Jillian N. Socea; Daren R. Ginete; Lakshminarayan M. Iyer; L. Aravind; Ronald K. Gary; Helen J. Wing; Paul Babitzke
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Crossref

VirB, a key transcriptional regulator ofShigellavirulence, requires a CTP ligand for its regulatory activities

2023-05-17 | Preprint
Contributors: Taylor M. Gerson; Audrey M. Ott; Monika MA. Karney; Jillian N. Socea; Daren R. Ginete; Lakshminarayan M. Iyer; L. Aravind; Ronald K. Gary; Helen J. Wing
Source: check_circle
Crossref

Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing

Nucleic Acids Research
2023-05-08 | Journal article
Contributors: Michael A Picker; Monika M A Karney; Taylor M Gerson; Alexander D Karabachev; Juan C Duhart; Joy A McKenna; Helen J Wing
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Crossref

The AraC/XylS Protein MxiE and Its Coregulator IpgC Control a Negative Feedback Loop in the Transcriptional Cascade That Regulates Type III Secretion in Shigella flexneri

Journal of Bacteriology
2022-07-19 | Journal article
Part of ISSN: 0021-9193
Part of ISSN: 1098-5530
Contributors: Helen J. Wing
Source: Self-asserted source
Helen J. Wing
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Preferred source (of 2)‎

The AraC/XylS protein MxiE and its co-regulator IpgC control a negative feedback loop in the transcription cascade that regulates type III secretion in Shigella flexneri

2022-04-21 | Preprint
Contributors: Joy A. McKenna; Monika MA. Karney; Daniel K. Chan; Natasha Weatherspoon-Griffin; Brianda Becerra Larios; Maria Carolina Pilonieta; George P. Munson; Helen J. Wing
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Crossref

VirB, a Key Transcriptional Regulator of Virulence Plasmid Genes in Shigella flexneri, Forms DNA-Binding Site-Dependent Foci in the Bacterial Cytoplasm

Journal of Bacteriology
2021-05-07 | Journal article
Part of ISSN: 0021-9193
Part of ISSN: 1098-5530
Contributors: Helen J. Wing
Source: Self-asserted source
Helen J. Wing
grade
Preferred source (of 2)‎

VirB, a key transcriptional regulator of virulence plasmid genes in Shigella flexneri, forms DNA-binding site dependent foci in the bacterial cytoplasm

2020-11-22 | Preprint
Contributors: Jillian N. Socea; Grant R. Bowman; Helen J. Wing
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Crossref

The Antiactivator of Type III Secretion, OspD1, Is Transcriptionally Regulated by VirB and H-NS from Remote Sequences in Shigella flexneri

Journal of Bacteriology
2020-04-27 | Journal article
Contributors: Joy A. McKenna; Helen J. Wing; Laurie E. Comstock
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Crossref

The Antiactivator of Type III Secretion, OspD1, Is Transcriptionally Regulated by VirB and H-NS from Remote Sequences in Shigella flexneri.

Journal of Bacteriology
2020-04-27 | Journal article
Source: Self-asserted source
Helen J. Wing

Investigating the DNA-Binding Site for VirB, a Key Transcriptional Regulator of Shigella Virulence Genes, Using an In Vivo Binding Tool.

Genes
2019-02-15 | Journal article
Source: Self-asserted source
Helen J. Wing

Insights into transcriptional silencing and anti-silencing in Shigella flexneri: a detailed molecular analysis of the icsP virulence locus

Molecular Microbiology
2018 | Journal article
EID:

2-s2.0-85044265610

Contributors: Weatherspoon-Griffin, N.; Picker, M.A.; Pew, K.L.; Park, H.S.; Ginete, D.R.; Karney, M.M.A.; Usufzy, P.; Castellanos, M.I.; Duhart, J.C.; Harrison, D.J. et al.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Characterization of SlyA in Shigella flexneri identifies a novel role in virulence

Infection and Immunity
2016 | Journal article
EID:

2-s2.0-84962786834

Contributors: Weatherspoon-Griffin, N.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

H-NS, its family members and their regulation of virulence genes in Shigella species

Genes
2016 | Journal article
EID:

2-s2.0-85004000425

Contributors: Picker, M.A.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

The Genetic Organization and Transcriptional Regulation of Shigella Virulence Genes.

Shigella: Molecular and Cellular Biology.
2016 | Book chapter | Writing - original draft
Contributors: Helen J. Wing
Source: Self-asserted source
Helen J. Wing

Comparison of in vitro methods for the production of Paenibacillus larvae endospores

Journal of Microbiological Methods
2015 | Journal article
EID:

2-s2.0-84962640737

Contributors: Alvarado, I.; Elekonich, M.M.; Abel-Santos, E.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Protocols to test the activity of antimicrobial peptides against the honey bee pathogen Paenibacillus larvae

Journal of Microbiological Methods
2015 | Journal article
EID:

2-s2.0-84937844012

Contributors: Khilnani, J.C.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

The Geogenomic Mutational Atlas of Pathogens (GoMAP) web system

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84899806105

Contributors: Sargeant, D.P.; Hedden, M.W.; Deverasetty, S.; Strong, C.L.; Alaniz, I.J.; Bartlett, A.N.; Brandon, N.R.; Brooks, S.B.; Brown, F.A.; Bufi, F. et al.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Characterization of the ospz promoter in shigella flexneri and its regulation by virb and h-ns

Journal of Bacteriology
2013 | Journal article
EID:

2-s2.0-84877949370

Contributors: Basta, D.W.; Pew, K.L.; Immak, J.A.; Park, H.S.; Picker, M.A.; Wigley, A.F.; Hensley, C.T.; Pearson, J.S.; Hartland, E.L.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Virf-independent regulation of shigella virB transcription is mediated by the small RNA RyhB

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84862181134

Contributors: Broach, W.H.; Egan, N.; Wing, H.J.; Payne, S.M.; Murphy, E.R.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

The iron-responsive Fur/RyhB regulatory cascade modulates the Shigella outer membrane protease icsp

Infection and Immunity
2011 | Journal article
EID:

2-s2.0-80855140142

Contributors: Africa, L.A.A.; Murphy, E.R.; Egan, N.R.; Wigley, A.F.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Two promoters and two translation start sites control the expression of the Shigella flexneri outer membrane protease IcsP

Archives of Microbiology
2011 | Journal article
EID:

2-s2.0-79954416875

Contributors: Hensley, C.T.; Kamneva, O.K.; Levy, K.M.; Labahn, S.K.; Africa, L.A.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

VirB alleviates H-NS repression of the icsP promoter in Shigella flexneri from sites more than one kilobase upstream of the transcription start site

Journal of Bacteriology
2009 | Journal article
EID:

2-s2.0-67549105464

Contributors: Castellanos, M.I.; Harrison, D.J.; Smith, J.M.; Labahn, S.K.; Levy, K.M.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Modulation of an outer membrane protease contributes to the virulence defect of Shigella flexneri strains carrying a mutation in the virK locus

Infection and Immunity
2005 | Journal article
EID:

2-s2.0-12844275382

Contributors: Wing, H.J.; Goldman, S.R.; Ally, S.; Goldberg, M.B.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Regulation of IcsP, the Outer Membrane Protease of the Shigella Actin Tail Assembly Protein IcsA, by Virulence Plasmid Regulators VirF and VirB

Journal of Bacteriology
2004 | Journal article
EID:

2-s2.0-1642581490

Contributors: Wing, H.J.; Yan, A.W.; Goldman, S.R.; Goldberg, M.B.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

A novel promoter architecture for microaerobic activation by the anaerobic transcription factor FNR

Molecular Microbiology
2001 | Journal article
EID:

2-s2.0-0035136782

Contributors: Marshall, F.A.; Messenger, S.L.; Wyborn, N.R.; Guest, J.R.; Wing, H.; Busby, S.J.W.; Green, J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Analysis of interactions between activating region 1 of Escherichia coli FNR protein and the C-terminal domain of the RNA polymerase α subunit: Use of alanine scanning and suppression genetics

Molecular Microbiology
2000 | Journal article
EID:

2-s2.0-0033822626

Contributors: Lee, D.J.; Wing, H.J.; Savery, N.J.; Busby, S.J.W.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Role of activating region 1 of Escherichia coli FNR protein in transcription activation at class II promoters

Journal of Biological Chemistry
2000 | Journal article
EID:

2-s2.0-0034666325

Contributors: Wing, H.J.; Green, J.; Guest, J.R.; Busby, S.J.W.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Repression of transcription initiation by Escherichia coli FNR protein: Repression by FNR can be simple

FEMS Microbiology Letters
1998 | Journal article
EID:

2-s2.0-0032526674

Contributors: Williams, S.M.; Wing, H.J.; Busby, S.J.W.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Transcription activation by Escherichia coli FNR protein: Similarities to, and differences from, the CRP paradigm

Nucleic Acids Research
1998 | Journal article
EID:

2-s2.0-0032078948

Contributors: Li, B.; Wing, H.; Lee, D.; Wu, H.-C.; Busby, S.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Transcription activation at Class I FNR-dependent promoters: Identification of the activating surface of FNR and the corresponding contact site in the C-terminal domain of the RNA polymerase α subunit

Nucleic Acids Research
1997 | Journal article
EID:

2-s2.0-0030761738

Contributors: Williams, S.M.; Savery, N.J.; Busby, S.J.W.; Wing, H.J.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Regulation of promoters by two transcription activators: Evidence for a 'simultaneous touching' model

Biochemical Society Transactions
1996 | Journal article
EID:

2-s2.0-0029997755

Contributors: Savery, N.; Belyaeva, T.; Wing, H.; Busby, S.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Spacing requirements for transcription activation by Escherichia coli FNR protein

Journal of Bacteriology
1995 | Journal article
EID:

2-s2.0-0028853643

Contributors: Wing, H.J.; Williams, S.M.; Busby, S.J.W.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Transcription activation at Escherichia coli promoters dependent on the cyclic AMP receptor protein: Effects of binding sequences for the RNA polymerase α-subunit

Biochemical Journal
1995 | Journal article
EID:

2-s2.0-0029011384

Contributors: Savery, N.J.; Rhodius, V.A.; Wing, H.J.; Busby, S.J.W.
Source: Self-asserted source
Helen J. Wing via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)