Personal information

Molecular Biology, Gene Transcription, Muscle Differentiation, Cancer Biology, Epigenetics, Pediatric Diseases

Biography

I am working as an Additional Professor of Human Genetics in National Institute of Mental Health and Neurosciences (NIMHANS), India

Activities

Employment (7)

National Institute of Mental Health and Neurosciences: Bengaluru, Karnataka, IN

2023-07-01 to present | Additional Professor (Human Genetics)
Employment
Source: Self-asserted source
Mathivanan Jothi

National Institute of Mental Health and Neuro Sciences: Bangalore, Karnataka, IN

2020-07-01 to 2023-06-30 | Associate Professor (Human Genetics)
Employment
Source: Self-asserted source
Mathivanan Jothi

National Institute of Mental Health and Neurosciences: Bangalore, Karnataka, IN

2017-01-05 to 2020-06-30 | Assistant Professor (Human Genetics)
Employment
Source: Self-asserted source
Mathivanan Jothi

Bharathiar University: Coimbatore, Tamil Nadu, IN

2014-06-08 to 2017-01-04 | UGC-Assistant Professor (Biotechnology)
Employment
Source: Self-asserted source
Mathivanan Jothi

Ospedale San Raffaele: Milano, Lombardia, IT

2013-03-01 to 2014-07-09 | DTI-IMPORT fellow (Division of Regenerative Medicine, Stem Cells and Gene Therapy)
Employment
Source: Self-asserted source
Mathivanan Jothi

Roswell Park Cancer Institute: Buffalo, NY, US

2008-04-01 to 2013-02-27 | Post-Doctoral Associate (Cell Stress Biology)
Employment
Source: Self-asserted source
Mathivanan Jothi

Cleveland Clinic: Cleveland, OH, US

2007-12-26 to 2008-03-31 | Post Doctoral Research Fellow (Molecular Genetics)
Employment
Source: Self-asserted source
Mathivanan Jothi

Education and qualifications (3)

National Institute of Mental Health and Neuro Sciences: Bangalore, Karnataka, IN

2003-04-24 to 2007-08-07 | PhD (Human Genetics)
Education
Source: Self-asserted source
Mathivanan Jothi

University of Madras: Chennai, TN, IN

2000-08-24 to 2002-05-02 | MSc (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Mathivanan Jothi

Bharathiar University: Coimbatore, Tamil Nadu, IN

1997-06-01 to 2000-04-31 | BSc (Biochemistry (Kongunadu College of Arts and Science))
Education
Source: Self-asserted source
Mathivanan Jothi

Professional activities (1)

American Association for Cancer Research: Philadelphia, PA, US

2010-01-08 to present | Active member
Membership
Source: Self-asserted source
Mathivanan Jothi

Funding (1)

Evaluation Of Pax3 As A Targeted Therapeutics For Pediatric Solid Tumors

2017-04-01 to 2018-03-31 | Grant
Science and Engineering Research Board (New Delhi, IN)
GRANT_NUMBER:

SERB_1987052588

Source: Self-asserted source
Mathivanan Jothi via DimensionsWizard

Works (26)

Metavinculin mediates differentiation cues into myogenic gene expression

2024-02-22 | Preprint
Contributors: Abinayaselvi Murugan; Nandeesh Bevinahalli Nanjegowda; Mathivanan Jothi
Source: check_circle
Crossref

Restoration of functional PAX3 transcriptional factor enhanced neuronal differentiation in PAX3b isoform-depleted neuroblastoma cells

Cell and Tissue Research
2023-01 | Journal article
Contributors: Narenkumar Muralidharan; Abinayaselvi Murugan; Prabhuraj Andiperumal Raj; Mathivanan Jothi
Source: check_circle
Crossref

Restoration of functional PAX3 transcriptional factor enhanced neuronal differentiation in PAX3b isoform depleted neuroblastoma cells

2022-07-18 | Preprint
Contributors: Narenkumar Muralidharan; Abinayaselvi Murugan; Prabhuraj Andiperumal Raj; Mathivanan Jothi
Source: check_circle
Crossref

A new 7-diethylamino-4-hydroxycoumarin based reversible colorimetric/fluorometric probe for sequential detection of Al3+/PPi and its potential use in biodetection and bioimaging applications

New Journal of Chemistry
2021 | Journal article
Contributors: Moorthy Mathivanan; Balamurugan Tharmalingam; Thangaraj Devaraj; Abinayaselvi Murugan; Chia-Her Lin; Mathivanan Jothi; Balasubramanian Murugesapandian
Source: check_circle
Crossref
grade
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Selective detection of pyrophosphate anion by zinc ensemble of C-3-symmetric triaminoguanidine-pyrrole conjugate and its biosensing applications

Analytica Chimica Acta
2020 | Journal article
Contributors: Tharmalingam, Balamurugan; Mathivanan, Moorthy; Mani, Kailasam Saravana; Kaminsky, Werner; Raghunath, Azhwar; Jothi, Mathivanan; Perumal, Ekambaram; Murugesapandian, Balasubramanian
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Smart phone assisted quinoline-hemicyanine based fluorescent probe for the selective detection of glutathione and the application in living cells

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
2020 | Journal article
Contributors: Mani, Kailasam Saravana; Rajamanik, Ramar; Ilanchelian, Malaichamy; Muralidharan, Narenkumar; Jothi, Mathivanan; Rajendran, Subramaniam Parameswaran
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Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells

Oncotarget
2018 | Journal article
Contributors: David W. Wolff; Min-Hyung Lee; Mathivanan Jothi; Munmun Mal; Fengzhi Li; Asoke K. Mal
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p38α MAPK disables KMT1A-mediated repression of myogenic differentiation program

Skeletal Muscle
2016 | Journal article
EID:

2-s2.0-84983364647

Contributors: Chatterjee, B.; Wolff, D.W.; Jothi, M.; Mal, M.; Mal, A.K.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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A Rare Presentation of Retiform Hemangioendothelioma in the External Auditory Canal

Case Reports in Otolaryngology
2014 | Journal article
Contributors: Ezhil Arasan Jothi; Muthuchitra Sundaram; Jeyalakshmidevi Namasivayam; Mathivanan Jothi
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Crossref
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Long noncoding RNAs, emerging players in muscle differentiation and disease

Skeletal Muscle
2014 | Journal article
EID:

2-s2.0-84897373291

Contributors: Neguembor, M.V.; Jothi, M.; Gabellini, D.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma

Molecular Cancer Therapeutics
2013 | Journal article
EID:

2-s2.0-84890518783

Contributors: Jothi, M.; Mal, M.; Keller, C.; Mal, A.K.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell

Cell Cycle
2012 | Journal article
EID:

2-s2.0-84857982296

Contributors: Jothi, M.; Nishijo, K.; Keller, C.; Mal, A.K.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma

Oncotarget
2012 | Journal article
EID:

2-s2.0-84872783337

Contributors: Jothi, M.; Mal, A.K.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier

Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma

Oncotarget
2012 | Journal article
Contributors: Mathivanan Jothi; Asoke K. Mal
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Histone methyltransferase KMT1A restrains entry of alveolar rhabdomyosarcoma cells into a myogenic differentiated state

Cancer Research
2011 | Journal article
EID:

2-s2.0-79957913522

Contributors: Lee, M.-H.; Jothi, M.; Gudkov, A.V.; Mal, A.K.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
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Transcriptionally inactive PAX3-FKHR fails to induce ARMS cells differentiation

Cancer Research
2010 | Journal article
Contributors: Jothi, Mathivanan; Keller, Charles; Mal, Asoke K.
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FUNCTIONAL MODULATION OF THE P53 GENE AND ITS PROTEIN IN HUMAN BRAIN TUMORS

Annals of Neurosciences
2008 | Journal article
Contributors: Keshava, Rohini; Jothi, Mathivanan; Gope, Mohan L.; Gope, Rajalakshmi
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Altered structure and deregulated expression of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors

Molecular and Cellular Biochemistry
2007 | Journal article
EID:

2-s2.0-34547618845

Contributors: Mathivanan, J.; Rohini, K.; Gope, M.L.; Anandh, B.; Gope, R.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
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Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors

Molecular and Cellular Biochemistry
2007 | Journal article
EID:

2-s2.0-34250009394

Contributors: Rohini, K.; Mathivanan, J.; Prabhu, P.D.A.H.; Subbakrishna, D.K.; Gope, M.L.; Chandramouli, B.A.; Sampath, S.; Anandh, B.; Gope, R.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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POSSIBLE ROLE OF THE TUMOR SUPPRESSOR GENE RETINOBLASTOMA (RBI) IN HUMAN BRAIN TUMOR DEVELOPMENT

Annals of Neurosciences
2007 | Journal article
Contributors: Jothi, Mathivanan; Keshava, Rohini; Gope, Mohan L.; Gope, Rajalakshmi
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Age dependent phosphorylation and deregulation of p53 in human vestibular schwannomas

Molecular Carcinogenesis
2006 | Journal article
EID:

2-s2.0-31044432520

Contributors: Dayalan, A.H.P.P.; Jothi, M.; Keshava, R.; Thomas, R.; Gope, M.L.; Doddaballapur, S.K.; Somanna, S.; Prabaraj, S.S.; Ashwathnarayanarao, C.B.; Gope, R.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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THE P53 GENE AND HUMAN VESTIBULAR SCHWANNOMAS

Annals of Neurosciences
2006 | Journal article
Contributors: Dayalan, Antony H. P. P.; Keshava, Rohini; Jothi, Mathivanan; Gope, Mohan L.; Gope, Rajalakshmi
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The P53 Gene And Human Vestibular Schwannomas (vol 13, pg 77, 2006)

Annals of Neurosciences
2006 | Journal article
Contributors: Dayalan, Antony H. P. P.; Keshava, Rohini; Jothi, Mathivanan; Gope, Mohan L.; Gope, Rajalakshmi
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THE TUMOR SUPPRESSOR GENE RETINOBLASTOMA (RB1) IN HUMAN VESTIBULAR SCHWANNOMAS

Annals of Neurosciences
2006 | Journal article
Contributors: Dayalan, Antony H. P. P.; Thomas, Remy; Jothi, Mathivanan; Keshava, Rohini; Gope, Mohan L.; Gope, Rajalakshmi
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Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas

Molecular and Cellular Biochemistry
2005 | Journal article
EID:

2-s2.0-20244368347

Contributors: Thomas, R.; Prabhu, P.D.A.H.; Mathivanan, J.; Rohini; Sivakumar, D.; Jayakumar, P.N.; Devi, B.I.; Satish, S.; Sastry, K.V.R.; Gope, R.
Source: Self-asserted source
Mathivanan Jothi via Scopus - Elsevier
grade
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Structure and expression of p53 gene and altered phosphorylation of p53 protein in human vestibular schwannomas

The FEBS Journal
2005 | Journal article
Contributors: Prabhu, PAH; Mathivanan, J; Rohini, K; Thomas, R; Chandramouli, B; Gope, R
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Peer review (20 reviews for 3 publications/grants)

Review activity for Asian Pacific journal of cancer prevention. (1)
Review activity for Journal of cellular physiology. (3)
Review activity for Life sciences. (16)