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Activities

Employment (1)

Color: Burlingame, CA, US

2015-06 to present | Chief Science Officer (Scientific Affairs)
Employment
Source: Self-asserted source
Alicia Y Zhou

Education and qualifications (3)

UCSF Medical Center: San Francisco, CA, US

2012-08-01 to 2015-06-01 | Postdoctoral Fellow (Cell and Tissue Biology)
Education
Source: Self-asserted source
Alicia Y Zhou

Harvard University: Cambridge, MA, US

2006-09 to 2012-05 | Ph.D. (Biological and Biomedical Sciences)
Education
Source: Self-asserted source
Alicia Y Zhou

Massachusetts Institute of Technology: Cambridge, MA, US

2002-09 to 2006-06 | B.S. (Biology)
Education
Source: Self-asserted source
Alicia Y Zhou

Professional activities (1)

American Society of Human Genetics: Bethesda, Maryland, US

Membership
Source: Self-asserted source
Alicia Y Zhou

Funding (2)

Color's software-powered, high-touch delivery of genetic counseling sessions and pharmacogenomics consultations for return of genomic results

2019-08 to 2024-08 | Award
NIH Office of the Director (Md., Md., US)
GRANT_NUMBER:

1OT2OD028251

Source: Self-asserted source
Alicia Y Zhou

Characterization of IKBKE as a Breast Cancer Oncogene

2007-10-01 to 2008-09-01 | Grant
Congressionally Directed Medical Research Programs (Fort Detrick, US)
GRANT_NUMBER:

W81XWH-08-1-0763

Source: Self-asserted source
Alicia Y Zhou via DimensionsWizard

Works (34)

Model-driven mitigation measures for reopening schools during the COVID-19 pandemic

Proceedings of the National Academy of Sciences
2021-09-28 | Journal article
Contributors: Ryan Seamus McGee; Julian R. Homburger; Hannah E. Williams; Carl T. Bergstrom; Alicia Y. Zhou
Source: check_circle
Crossref

Proactive COVID-19 testing in a partially vaccinated population

2021-08-18 | Other
Contributors: Ryan S. McGee; Julian R. Homburger; Hannah E. Williams; Carl T. Bergstrom; Alicia Y. Zhou
Source: check_circle
Crossref

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.

Nature communications
2020-08-20 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Burden of hereditary cancer susceptibility in unselected patients with pancreatic ductal adenocarcinoma referred for germline screening.

Cancer medicine
2020-04-07 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Choosing a New Direction on a One-Way Street.

Cell
2020-04-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou

LEAP: Using machine learning to support variant classification in a clinical setting.

Human mutation
2020-04-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Patient acceptance of genetic testing for familial hypercholesterolemia in the CASCADE FH Registry

Journal of Clinical Lipidology
2020-03 | Journal article
Contributors: Samuel S. Gidding; Amanda Sheldon; Cynthia L. Neben; Hannah E. Williams; Sherman Law; Alicia Y. Zhou; Katherine Wilemon; Catherine D. Ahmed; Iris Kindt
Source: check_circle
Crossref

Color Data v2: a user-friendly, open-access database with hereditary cancer and hereditary cardiovascular conditions datasets.

Database : the journal of biological databases and curation
2020-01-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2019-12-23 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores.

Genome medicine
2019-11-26 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Ethnic disparities among men with prostate cancer undergoing germline testing.

Urologic oncology
2019-10-17 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Multi-Gene Panel Testing of 23,179 Individuals for Hereditary Cancer Risk Identifies Pathogenic Variant Carriers Missed by Current Genetic Testing Guidelines.

The Journal of molecular diagnostics : JMD
2019-06-11 | Journal article
Source: Self-asserted source
Alicia Y Zhou

A scalable, aggregated genotypic-phenotypic database for human disease variation.

Database : the journal of biological databases and curation
2019-01-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Cascade Genetic Testing of Relatives for Hereditary Cancer Risk: Results of an Online Initiative.

Journal of the National Cancer Institute
2019-01-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Rare <i>TP53</i> variant associated with Li-Fraumeni syndrome exhibits variable penetrance in a Saudi family.

NPJ genomic medicine
2018-12-19 | Journal article
Source: Self-asserted source
Alicia Y Zhou

Identification of a novel GREM1 duplication in a patient with multiple colon polyps.

Familial cancer
2018-05 | Journal article
Contributors: McKenna DB; Van Den Akker J; Zhou AY; Ryan L; Leon A; O'Connor R; Shah PD; Rustgi AK; Katona BW
Source: Self-asserted source
Alicia Y Zhou via Europe PubMed Central

A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing.

BMC genomics
2018-04 | Journal article
Contributors: van den Akker J; Mishne G; Zimmer AD; Zhou AY
Source: Self-asserted source
Alicia Y Zhou via Europe PubMed Central

Inherited predisposition to breast and ovarian cancer in non-Jewish populations in Israel.

Breast cancer research and treatment
2017-08-21 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Cancer recurrence monitoring using hyperpolarized [1-<sup>13</sup>C]pyruvate metabolic imaging in murine breast cancer model.

Magnetic resonance imaging
2017-07-15 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.

Nature medicine
2016-10-24 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer.

Nature medicine
2016-03-07 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.

Human molecular genetics
2015-10-15 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Cancer discovery
2014-12-12 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

TRAF2 is an NF-κB-activating oncogene in epithelial cancers.

Oncogene
2013-12-23 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.

eLife
2013-10-15 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex.

Cell reports
2013-02-28 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Structure and ubiquitination-dependent activation of TANK-binding kinase 1.

Cell reports
2013-02-28 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation.

Molecular and cellular biology
2012-09-24 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Characterization of IKBKE as a Breast Cancer Oncogene

2011-10-01 | Report
Contributors: Alicia Zhou
Source: Self-asserted source
Alicia Y Zhou via Crossref Metadata Search

Characterization of IKBKE as a Breast Cancer Oncogene

2010-10 | Report
Contributors: Alicia Zhou
Source: Self-asserted source
Alicia Y Zhou via Crossref Metadata Search

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.

Proceedings of the National Academy of Sciences of the United States of America
2010-08-16 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Characterization of IKBKE as a Breast Cancer Oncogene

2009-10-01 | Report
Contributors: Alicia Zhou
Source: Self-asserted source
Alicia Y Zhou via Crossref Metadata Search

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.

Molecular cell
2009-05-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

The epithelial-mesenchymal transition generates cells with properties of stem cells.

Cell
2008-05-01 | Journal article
Source: Self-asserted source
Alicia Y Zhou
grade
Preferred source (of 2)‎

Peer review (8 reviews for 4 publications/grants)

Review activity for American journal of human genetics. (2)
Review activity for Biochimica et biophysica acta. (3)
Review activity for Genetics in medicine. (2)
Review activity for Nature genetics. (1)