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Cancer, Cell-free DNA, Next-generation sequencing, Digital droplet PCR, Quantitative PCR, Liquid biopsy, Circulating tumour cells
United Kingdom

Activities

Employment (6)

University of Leicester: Leicester, Leicestershire, GB

2024-08-01 to present | Associate Professor (Genetics, Genomics and Cancer Sciences)
Employment
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2017-01-01 to 2024-07-31 | Lecturer in Cancer Early Detection (Leicester Cancer Research Centre)
Employment
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2012-04-01 to 2016-12-31 | Senior Research Associate (Cancer Studies)
Employment
Source: Self-asserted source
David Guttery

University of Nottingham: Nottingham, Nottinghamshire, GB

2010-04-01 to 2012-03-31 | Research Fellow (Genetics and Genomics)
Employment
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2009-08-01 to 2010-03-31 | Research Associate (Cancer Studies)
Employment
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2008-11-01 to 2009-08-01 | Postdoctoral Scientist (MRC Toxicology Unit)
Employment
Source: Self-asserted source
David Guttery

Education and qualifications (4)

University of Leicester: Leicester, England, GB

2017-09-01 to 2019-05-31 | PGCAPP (College of Life Sciences)
Qualification
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2005-09-01 to 2008-10-01 | PhD in Molecular Breast Pathology (Cancer Studies)
Education
Source: Self-asserted source
David Guttery

University of Leicester: Leicester, Leicestershire, GB

2004-09-01 to 2005-07-01 | MSc in Molecular Pathology and Toxicology (Cancer Studies)
Education
Source: Self-asserted source
David Guttery

University of Wolverhampton: Wolverhampton, Staffordshire, GB

1999-09-01 to 2003-06-01 | BSc (Hons) Medicinal Biochemistry (Applied Sciences)
Education
Source: Self-asserted source
David Guttery

Professional activities (1)

Higher Education Academy: York, GB

2019-06-26 to present | Fellow
Membership
Source: Self-asserted source
David Guttery

Funding (6)

Can Artificial Intelligence predict the tumour genotype of screen-detected breast cancers by analysing mammograms?

2018-10 to 2019-10 | Grant
LPMI/Hope Against Cancer (Leicester, GB)
Source: Self-asserted source
David Guttery

Nucleosome mapping of circulating DNA as a surrogate for tracking transcriptional reprogramming in endocrine therapy-resistant metastatic breast cancer

2018-10 to 2019-10 | Grant
Royal Society (London, GB)
GRANT_NUMBER:

RGS\R2\180088

Source: Self-asserted source
David Guttery

Utilising Cancer Genetic Evolution for Early Detection and Monitoring of Breast Cancer

2017-03 to 2022-03 | Award
Cancer Research UK (London, GB)
Source: Self-asserted source
David Guttery

Targeted sequencing of cell-free DNA to detect acquired resistance to hormonal therapy in ER-positive breast cancer.

2014-06 to 2014-12 | Grant
University of Leicester (Leicester, Leicestershire, GB)
Source: Self-asserted source
David Guttery

Targeted deep sequencing of cfDNA for real-time monitoring of breast cancer

Source: Self-asserted source
David Guttery via DimensionsWizard

The ECMC cross-centre placement and skills sharing scheme

2014-03 to 2015-03 | Grant
Experimental Cancer Medicine Centre (Leicester, Leicester, GB)
Source: Self-asserted source
David Guttery

Works (50 of 59)

Items per page:
Page 1 of 2

DivergentPlasmodiumkinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis

Life Science Alliance
2025-06 | Journal article
Contributors: Ryuji Yanase; Mohammad Zeeshan; David JP Ferguson; Robert Markus; Declan Brady; Andrew R Bottrill; Anthony A Holder; David S Guttery; Rita Tewari
Source: check_circle
Crossref

DivergentPlasmodiumkinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis

2024-09-22 | Preprint
Contributors: Ryuji Yanase; Mohammad Zeeshan; David J. P. Ferguson; Robert Marcus; Declan Brady; Andrew R. Bottrill; Anthony A. Holder; David S. Guttery; Rita Tewari
Source: check_circle
Crossref

BioMalPar XX: looking back on, and forward from, 20 years of malaria research

Trends in Parasitology
2024-08 | Journal article
Contributors: Nedal-Djamil Darif; Markus Ganter; Jerzy Michal Dziekan; Nicole Kilian; Nicolas Brancucci; Caroline Ng; Laura E. de Vries; David Guttery; Nisha Philip; Justin A. Boddey et al.
Source: check_circle
Crossref

The molecular mechanisms driving Plasmodium cell division

Biochemical Society Transactions
2024-04-24 | Journal article
Contributors: David S. Guttery; Mohammad Zeeshan; Anthony A. Holder; Rita Tewari
Source: check_circle
Crossref

Meiosis in Plasmodium: how does it work?

Trends in Parasitology
2023-10 | Journal article
Contributors: David S. Guttery; Mohammad Zeeshan; Anthony A. Holder; Eelco C. Tromer; Rita Tewari
Source: check_circle
Crossref

GFNet: A Deep Learning Framework for Breast Mass Detection

Electronics
2023-03-28 | Journal article
Contributors: Xiang Yu; Ziquan Zhu; Yoav Alon; David S. Guttery; Yudong Zhang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Comparison of phenomics and cfDNA in a large breast screening population: the Breast Screening and Monitoring Study (BSMS)

Oncogene
2023-03-10 | Journal article
Contributors: Justin Stebbing; Panteleimon G. Takis; Caroline J. Sands; Lynn Maslen; Matthew R. Lewis; Kelly Gleason; Karen Page; David Guttery; Daniel Fernandez-Garcia; Lindsay Primrose et al.
Source: check_circle
Crossref

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

British Journal of Cancer
2022-11-09 | Journal article
Contributors: Daniel Fernandez-Garcia; Georgios Nteliopoulos; Robert K. Hastings; Amelia Rushton; Karen Page; Rebecca C. Allsopp; Bana Ambasager; Kelly Gleason; David S. Guttery; Simak Ali et al.
Source: check_circle
Crossref

PeMNet for Pectoral Muscle Segmentation

Biology
2022-01-14 | Journal article
Contributors: Xiang Yu; Shui-Hua Wang; Juan Manuel Górriz; Xian-Wei Jiang; David S. Guttery; Yu-Dong Zhang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Deep Spatio-Temporal Representation and Ensemble Classification for Attention Deficit/Hyperactivity Disorder

IEEE Transactions on Neural Systems and Rehabilitation Engineering
2021 | Journal article
Contributors: Shuaiqi Liu; Ling Zhao; Xu Wang; Qi Xin; Jie Zhao; David S. Guttery; Yu-Dong Zhang
Source: check_circle
Crossref

ResNet-SCDA-50 for Breast Abnormality Classification

IEEE/ACM Transactions on Computational Biology and Bioinformatics
2021-01-01 | Journal article
Contributors: Xiang Yu; Cheng Kang; David S. Guttery; Seifedine Kadry; Yang Chen; Yu-Dong Zhang
Source: check_circle
Crossref

Plasmodium DEH is ER-localized and crucial for oocyst mitotic division during malaria transmission

Life Science Alliance
2020-12 | Journal article
Contributors: David S Guttery; Rajan Pandey; David JP Ferguson; Richard J Wall; Declan Brady; Dinesh Gupta; Anthony A Holder; Rita Tewari
Source: check_circle
Crossref

MRE11 Is Crucial for Malaria Parasite Transmission and Its Absence Affects Expression of Interconnected Networks of Key Genes Essential for Life

Cells
2020-12-03 | Journal article
Contributors: David S. Guttery; Abhinay Ramaprasad; David J. P. Ferguson; Mohammad Zeeshan; Rajan Pandey; Declan Brady; Anthony A. Holder; Arnab Pain; Rita Tewari
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

MRE11 is crucial for malaria transmission and its absence affects expression of interconnected networks of key genes essential for life

2020-08-24 | Preprint
Contributors: David S. Guttery; Abhinay Ramaprasad; David J. P. Ferguson; Mohammad Zeeshan; Rajan Pandey; Declan Brady; Anthony A. Holder; Arnab Pain; Rita Tewari
Source: check_circle
Crossref

Utility of Circulating Tumor DNA for Detection and Monitoring of Endometrial Cancer Recurrence and Progression

Cancers
2020-08-10 | Journal article
Contributors: Esther L. Moss; Diviya N. Gorsia; Anna Collins; Pavandeep Sandhu; Nalini Foreman; Anupama Gore; Joey Wood; Christopher Kent; Lee Silcock; David S. Guttery
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Patient acceptability of ctDNA testing in endometrial cancer follow-up

2020-07-16 | Other
Contributors: A Relton; A Collins; DS Guttery; D Gorsia; HJ McDermott; EL Moss
Source: check_circle
Crossref

Differences in the molecular profile of endometrial cancers from British White and British South Asian women

PLOS ONE
2020-06-10 | Journal article
Contributors: Konstantinos Polymeros; Hiromu Suzuki; David S. Guttery; Roger Hew; Rachael Bishop; Elizabeth Stannard; Salvador Macip; Paul Symonds; Esther L. Moss
Source: check_circle
Crossref

Utility of circulating tumor DNA for detection and monitoring of endometrial cancer recurrence and progression

2020-03-06 | Other
Contributors: Esther L. Moss; Diviya N. Gorsia; Anna Collins; Pavandeep Sandhu; Nalini Foreman; Anu Gore; Joey Wood; Christopher Kent; Lee Silcock; David S. Guttery
Source: check_circle
Crossref

A Heuristic Neural Network Structure Relying on Fuzzy Logic for Images Scoring

IEEE Transactions on Fuzzy Systems
2020-01-13 | Journal article
Part of ISSN: 1063-6706
Part of ISSN: 1941-0034
Source: Self-asserted source
David Guttery
grade
Preferred source (of 2)‎

In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth—a clinically relevant distinction

Modern Pathology
2019 | Journal article
EID:

2-s2.0-85063809488

Contributors: Moore, D.A.; Sereno, M.; Das, M.; Baena Acevedo, J.D.; Sinnadurai, S.; Smith, C.; McSweeney, A.; Su, X.; Officer, L.; Jones, C. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Real-time dynamics of Plasmodium NDC80 as a marker for the kinetochore during atypical mitosis and meiosis

2019-09-13 | Other
Contributors: Rajan Pandey; Mohammad Zeeshan; David J.P. Ferguson; Robert Markus; Declan Brady; Emilie Daniel; Rebecca R. Stanway; Anthony A. Holder; David S. Guttery; Rita Tewari
Source: check_circle
Crossref

The liquid biopsy: towards standardisation in preparation for prime time.

The Lancet. Oncology
2019-06-01 | Journal article
Source: Self-asserted source
David Guttery

Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence

Clinical Cancer Research
2019-04-16 | Journal article
Part of ISSN: 1078-0432
Part of ISSN: 1557-3265
Source: Self-asserted source
David Guttery

Alcoholism Identification Based on an AlexNet Transfer Learning Model.

Frontiers in Psychiatry
2019-04-11 | Journal article
Source: Self-asserted source
David Guttery

Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

Cell Death and Disease
2018 | Journal article
EID:

2-s2.0-85052700588

Contributors: Myint, N.N.M.; Verma, A.M.; Fernandez-Garcia, D.; Sarmah, P.; Tarpey, P.S.; Al-Aqbi, S.S.; Cai, H.; Trigg, R.; West, K.; Howells, L.M. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Correction: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women [Breast Cancer Res., 12, 4, (2010) (R57)] DOI: 10.1186/bcr2618

Breast Cancer Research
2018 | Journal article
EID:

2-s2.0-85051021786

Contributors: Guttery, D.S.; Hancox, R.A.; Mulligan, K.T.; Hughes, S.; Lambe, S.M.; Howard Pringle, J.; Walker, R.A.; Louise Jones, J.; Shaw, J.A.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Erratum to: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis (Scientific Reports, (2018), 8, 1, (5610), 10.1038/s41598-018-23871-9)

Scientific Reports
2018 | Journal article
EID:

2-s2.0-85051852109

Contributors: Wall, R.J.; Ferguson, D.J.P.; Freville, A.; Franke-Fayard, B.; Brady, D.; Zeeshan, M.; Bottrill, A.R.; Wheatley, S.; Fry, A.M.; Janse, C.J. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Racial differences in endometrial cancer molecular portraits in The Cancer Genome Atlas

Oncotarget
2018 | Journal article
EID:

2-s2.0-85044789836

Contributors: Guttery, D.S.; Blighe, K.; Polymeros, K.; Paul Symonds, R.; Macip, S.; Moss, E.L.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Scientific reports
2018-04 | Journal article
Contributors: Wall RJ; Ferguson DJP; Freville A; Franke-Fayard B; Brady D; Zeeshan M; Bottrill AR; Wheatley S; Fry AM; Janse CJ et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Next generation sequencing of circulating cell-free DNA for evaluating mutations and gene amplification in metastatic breast cancer

Clinical Chemistry
2017 | Journal article
EID:

2-s2.0-85011628861

Contributors: Page, K.; Guttery, D.S.; Fernandez-Garcia, D.; Hills, A.; Hastings, R.K.; Luo, J.; Goddard, K.; Shahin, V.; Woodley-Barker, L.; Rosales, B.M. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

The genetics of gastroesophageal adenocarcinoma and the use of circulating cell free DNA for disease detection and monitoring

Expert Review of Molecular Diagnostics
2017 | Journal article
EID:

2-s2.0-85018645344

Contributors: Openshaw, M.R.; Richards, C.J.; Guttery, D.S.; Shaw, J.A.; Thomas, A.L.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.

Scientific reports
2017-11 | Journal article
Contributors: Saini E; Zeeshan M; Brady D; Pandey R; Kaiser G; Koreny L; Kumar P; Thakur V; Tatiya S; Katris NJ et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts.

2017-01 | Journal article
Contributors: Shaw JA; Guttery DS; Hills A; Fernandez-Garcia D; Page K; Rosales BM; Goddard KS; Hastings RK; Luo J; Ogle O et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer.

2016-12 | Journal article
Contributors: Page K; Guttery DS; Fernandez-Garcia D; Hills A; Hastings RK; Luo J; Goddard K; Shahin V; Woodley-Barker L; Rosales BM et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central

The role of ctDNA detection and the potential of the liquid biopsy for breast cancer monitoring.

2016-07 | Journal article
Contributors: Openshaw MR; Page K; Fernandez-Garcia D; Guttery D; Shaw JA
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

The pioneer factor PBX1 is a novel driver of metastatic progression in ER'-positive breast cancer

Oncotarget
2015 | Journal article
EID:

2-s2.0-84941215567

Contributors: Magnani, L.; Patten, D.K.; Nguyen, V.T.; Hong, S.-P.; Steel, J.H.; Patel, N.; Lombardo, Y.; Faronato, M.; Gomes, A.R.; Woodley, L. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes.

2015-11 | Journal article
Contributors: Roques M; Wall RJ; Douglass AP; Ramaprasad A; Ferguson DJ; Kaindama ML; Brusini L; Joshi N; Rchiad Z; Brady D et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Commit and Transmit: Molecular Players in Plasmodium Sexual Development and Zygote Differentiation.

2015-09 | Journal article
Contributors: Guttery DS; Roques M; Holder AA; Tewari R
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer.

2015-09 | Journal article
Contributors: Magnani L; Patten DK; Nguyen VT; Hong SP; Steel JH; Patel N; Lombardo Y; Faronato M; Gomes AR; Woodley L et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central

Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor-Positive Metastatic Breast Cancer.

2015-07 | Journal article
DOI:

10.1373/clinchem.2015.238717

PMID:

25979954

Contributors: Guttery DS; Page K; Hills A; Woodley L; Marchese SD; Rghebi B; Hastings RK; Luo J; Pringle JH; Stebbing J et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes.

2014 | Journal article
DOI:

10.1371/journal.pone.0115346

PMID:

25546409

PMC:

PMC4278903

Contributors: Blighe K; Kenny L; Patel N; Guttery DS; Page K; Gronau JH; Golshani C; Stebbing J; Coombes RC; Shaw JA
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer.

2014-12 | Journal article
DOI:

10.1007/s10549-014-3183-4

PMID:

25395314

Contributors: Palmieri C; Cleator S; Kilburn LS; Kim SB; Ahn SH; Beresford M; Gong G; Mansi J; Mallon E; Reed S et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation.

2014-07 | Journal article
DOI:

10.1016/j.chom.2014.05.020

PMID:

25011111

Contributors: Guttery DS; Poulin B; Ramaprasad A; Wall RJ; Ferguson DJ; Brady D; Patzewitz EM; Whipple S; Straschil U; Wright MH et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

An Ancient Protein Phosphatase, SHLP1, Is Critical to Microneme Development in Plasmodium Ookinetes and Parasite Transmission

Cell Reports
2013 | Journal article
DOI:

10.1016/j.celrep.2013.01.032

Contributors: Brady, D.; Ferguson, D.J.P.; Guttery, D.S.; Holder, A.A.; Patzewitz, E.-M.; Poulin, B.; Ramakrishnan, C.; Szöodoubleacuter, B.; Tewari, R.; Wall, R.J.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Determination of breast cancer dormancy: Analysis of circulating free DNA using SNP 6.0 arrays

Tumor Dormancy, Quiescence, and Senescence: Aging, Cancer, and Noncancer Pathologies
2013 | Book
EID:

2-s2.0-85027287313

Contributors: Shaw, J.; Blighe, K.; Page, K.; Guttery, D.; Coombes, R.C.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Hide and seek: Tell-tale signs of breast cancer lurking in the blood

Cancer and Metastasis Reviews
2013 | Journal article
DOI:

10.1007/s10555-012-9414-4

Contributors: Blighe, K.; Coombes, R.C.; Guttery, D.S.; Hills, A.; Marchese, S.D.; Page, K.; Shaw, J.A.; Stebbing, J.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

Influence of plasma processing on recovery and analysis of circulating nucleic acids.

2013 | Journal article
DOI:

10.1371/journal.pone.0077963

PMID:

24205045

PMC:

PMC3799744

Contributors: Page K; Guttery DS; Zahra N; Primrose L; Elshaw SR; Pringle JH; Blighe K; Marchese SD; Hills A; Woodley L et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite.

2013 | Journal article
DOI:

10.1242/bio.20136163

PMID:

24244852

PMC:

PMC3828762

Contributors: Poulin B; Patzewitz EM; Brady D; Silvie O; Wright MH; Ferguson DJ; Wall RJ; Whipple S; Guttery DS; Tate EW et al.
Source: Self-asserted source
David Guttery via Europe PubMed Central
grade
Preferred source (of 2)‎

A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development

PLoS Pathogens
2012 | Journal article
DOI:

10.1371/journal.ppat.1002554

Contributors: Brady, D.; Ferguson, D.J.P.; Guttery, D.S.; Holder, A.A.; Janse, C.J.; Klop, O.; Nieduszynski, C.A.; Poulin, B.; Sandrini, S.M.; Solyakov, L. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier

A Unique Protein Phosphatase with Kelch-Like Domains (PPKL) in Plasmodium Modulates Ookinete Differentiation, Motility and Invasion

PLoS Pathogens
2012 | Journal article
DOI:

10.1371/journal.ppat.1002948

Contributors: Brady, D.; Carroll, P.L.; Ferguson, D.J.P.; Green, J.L.; Guttery, D.S.; Holder, A.A.; Patzewitz, E.-M.; Poulin, B.; Ramakrishnan, C.; Sinden, R.E. et al.
Source: Self-asserted source
David Guttery via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (16 reviews for 9 publications/grants)

Review activity for BMJ open. (1)
Review activity for British journal of cancer. (3)
Review activity for Cell death discovery. (1)
Review activity for Cells. (1)
Review activity for EBioMedicine. (1)
Review activity for Genome medicine. (5)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
Review activity for Targeted oncology. (2)