Personal information

Other IDs

Loop profile: 589287

Activities

Collapse all

Employment (3)

Paul-Ehrlich-Institut: Langen, DE

2015-06-01 to present | PostDoc-Fellow (Molecular Biotechnology and Gene Therapy)
Employment
Source: Self-asserted source
Frederic B. Thalheimer

Goethe University Frankfurt DE: Frankfurt am Main, Hessen, DE

2012-12-01 to 2015-05-31 | PhD Candidate and Junior PostDoc (LOEWE Center for Cell and Gene Therapy and Department of Medicine)
Employment
Source: Self-asserted source
Frederic B. Thalheimer

Georg-Speyer-Haus: Frankfurt, DE

2009-11-01 to 2012-11-29 | PhD Student (Cellular Immunity)
Employment
Source: Self-asserted source
Frederic B. Thalheimer

Works (19)

Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models

EMBO Molecular Medicine
2024-03-21 | Journal article
DOI: 10.1038/s44321-024-00055-9
Contributors: Arezoo Jamali; Naphang Ho; Angela Braun; Elham Adabi; Frederic B Thalheimer; Christian J Buchholz
Source: check_circle
Crossref

AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery

Biomaterials
2023-12 | Journal article
DOI: 10.1016/j.biomaterials.2023.122399
Contributors: Samuel A. Theuerkauf; Elena Herrera-Carrillo; Fabian John; Luca J. Zinser; Mariano A. Molina; Vanessa Riechert; Frederic B. Thalheimer; Kathleen Börner; Dirk Grimm; Petr Chlanda et al.
Source: check_circle
Crossref

In vivo generation of CAR T cells in the presence of human myeloid cells

Molecular Therapy - Methods & Clinical Development
2022-09 | Journal article
DOI: 10.1016/j.omtm.2022.06.004
Contributors: Naphang Ho; Shiwani Agarwal; Michela Milani; Alessio Cantore; Christian J. Buchholz; Frederic B. Thalheimer
Source: check_circle
Crossref

Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.

Blood advances
2020-11-01 | Journal article
DOI: 10.1182/bloodadvances.2020002229
PMID: 33216892
PMC: PMC7686896
Source: Self-asserted source
Frederic B. Thalheimer

Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4.

Frontiers in immunology
2020-08-28 | Journal article
DOI: 10.3389/fimmu.2020.02028
PMID: 32983147
PMC: PMC7483584
Source: Self-asserted source
Frederic B. Thalheimer

In Vivo Generation of CAR T Cells Selectively in Human CD4<sup>+</sup> Lymphocytes.

Molecular therapy : the journal of the American Society of Gene Therapy
2020-05-16 | Journal article
DOI: 10.1016/j.ymthe.2020.05.005
PMID: 32485137
Source: Self-asserted source
Frederic B. Thalheimer

In vivo generated human CAR T cells eradicate tumor cells

OncoImmunology
2019-12-02 | Journal article
DOI: 10.1080/2162402x.2019.1671761
Part of ISSN: 2162-402X
Source: Self-asserted source
Frederic B. Thalheimer

GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.

Molecular therapy. Methods & clinical development
2019-07-23 | Journal article
DOI: 10.1016/j.omtm.2019.07.004
PMID: 31463334
PMC: PMC6706527
Source: Self-asserted source
Frederic B. Thalheimer

Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

Frontiers in Oncology
2019-02-14 | Journal article
DOI: 10.3389/fonc.2019.00052
Part of ISSN: 2234-943X
Source: Self-asserted source
Frederic B. Thalheimer

In vivo generation of human CD 19‐ CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

EMBO Molecular Medicine
2018-11 | Journal article
DOI: 10.15252/emmm.201809158
Part of ISSN: 1757-4676
Part of ISSN: 1757-4684
Source: Self-asserted source
Frederic B. Thalheimer

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy

Cell
2017-05 | Journal article
DOI: 10.1016/j.cell.2017.04.018
Part of ISSN: 0092-8674
Source: Self-asserted source
Frederic B. Thalheimer

DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival.

Stem cells (Dayton, Ohio)
2016-01-26 | Journal article
DOI: 10.1002/stem.2282
PMID: 26731607
PMC: PMC4832267
Source: Self-asserted source
Frederic B. Thalheimer

STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.

Nature communications
2015-11-25 | Journal article
DOI: 10.1038/ncomms9928
PMID: 26603207
PMC: PMC4674773
Source: Self-asserted source
Frederic B. Thalheimer

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal.

Cell reports
2015-06-18 | Journal article
DOI: 10.1016/j.celrep.2015.05.038
PMID: 26095368
Source: Self-asserted source
Frederic B. Thalheimer

The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia.

PLoS genetics
2015-04-28 | Journal article
DOI: 10.1371/journal.pgen.1005144
PMID: 25919613
PMC: PMC4412790
Source: Self-asserted source
Frederic B. Thalheimer

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Nature
2015-02-18 | Journal article
DOI: 10.1038/nature14131
PMID: 25707806
Source: Self-asserted source
Frederic B. Thalheimer

Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.

Stem cell reports
2014-06-19 | Journal article
DOI: 10.1016/j.stemcr.2014.05.010
PMID: 25068120
PMC: PMC4110750
Source: Self-asserted source
Frederic B. Thalheimer

Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells.

Proceedings of the National Academy of Sciences of the United States of America
2013-12-03 | Journal article
DOI: 10.1073/pnas.1312509110
PMID: 24302766
PMC: PMC3870723
Source: Self-asserted source
Frederic B. Thalheimer

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.

Blood
2010-10-22 | Journal article
DOI: 10.1182/blood-2010-07-292722
PMID: 20971954
Source: Self-asserted source
Frederic B. Thalheimer
How many people are using ORCID?