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Scopus Author ID: 55206255300

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Employment (1)

University of Nebraska Medical Center: Omaha, Nebraska, US

2020-10-01 to present | Assistant Professor (Pathology, Microbiology, and Immunology)
Employment
Source: Self-asserted source
Leonardo Augusto

Works (22)

Francisella tularensis universal stress protein contributes to persistence during growth arrest and paraquat-induced superoxide stress

Journal of Bacteriology
2025-02-20 | Journal article
DOI: 10.1128/jb.00377-24
Contributors: Benjamin Girardo; Yinshi Yue; Oksana Lockridge; Amanda M. Bartling; Lawrence M. Schopfer; Leonardo Augusto; Marilynn A. Larson; Michael Y. Galperin
Source: check_circle
Crossref

Metabolic Adaptability and Nutrient Scavenging in Toxoplasma gondii: Insights from Ingestion Pathway-Deficient Mutants

2024-11-27 | Preprint
DOI: 10.1101/2024.11.27.625683
Contributors: Patrick A. Rimple; Einar B. Olafsson; Benedikt M. Markus; Fengrong Wang; Leonardo Augusto; Sebastian Lourido; Vern B. Carruthers
Source: check_circle
Crossref

Synthetic hemozoin as a nanocarrier for cross-presentation

Immunobiology
2024-09 | Journal article
DOI: 10.1016/j.imbio.2024.152837
Part of ISSN: 0171-2985
Contributors: Letícia Torres-Dias; Rebeca Santana Souza; Jessica Carolina Alves Moreira; Douglas de Oliveira Paggi; Jônatas Bussador do Amaral; André Luis Lacerda Bachi; Leonardo Augusto; Marina Tiemi Shio
Source: Self-asserted source
Leonardo Augusto

Coxiella burnetii inhibits nuclear translocation of TFEB, the master transcription factor for lysosomal biogenesis

Journal of Bacteriology
2024-08-22 | Journal article
DOI: 10.1128/jb.00150-24
Contributors: Brigham Killips; Emily J. Bremer Heaton; Leonardo Augusto; Anders Omsland; Stacey D. Gilk; Patricia A. Champion
Source: check_circle
Crossref

Selective host autophagy is induced during the intracellular parasite Toxoplasma gondii infection controlling amino acid levels

mSphere
2024-07-30 | Journal article
DOI: 10.1128/msphere.00369-24
Contributors: Matthew D. White; Rajendra K. Angara; Leticia Torres Dias; Dhananjay D. Shinde; Vinai C. Thomas; Leonardo Augusto; Ira J. Blader
Source: check_circle
Crossref

Host autophagy is exploited by the intracellular parasiteToxoplasma gondiito enhance amino acids levels

2023-12-08 | Preprint
DOI: 10.1101/2023.12.08.570852
Contributors: Matthew D. White; Rajendra K. Angara; Leticia Torres Dias; Dhananjay D. Shinde; Vinai C. Thomas; Leonardo Augusto
Source: check_circle
Crossref

<i>Coxiella burnetii</i>actively blocks IL-17-induced oxidative stress in macrophages

2023-03-15 | Preprint
DOI: 10.1101/2023.03.15.532774
Contributors: Tatiana M. Clemente; Leonardo Augusto; Rajendra K. Angara; Stacey Gilk
Source: Self-asserted source
Leonardo Augusto

Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche

mBio
2022-02-22 | Journal article
DOI: 10.1128/mbio.03073-21
Part of ISSN: 2150-7511
Source: Self-asserted source
Leonardo Augusto

TgIF2K-B Is an eIF2α Kinase in Toxoplasma gondii That Responds to Oxidative Stress and Optimizes Pathogenicity.

mBio
2021-01-26 | Journal article
DOI: 10.1128/mbio.03160-20
PMID: 33500345
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Host sensing and signal transduction during Toxoplasma stage conversion.

Molecular microbiology
2020-10-28 | Journal article
DOI: 10.1111/mmi.14634
PMID: 33118234
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Toxoplasma gondii Co-opts the Unfolded Protein Response To Enhance Migration and Dissemination of Infected Host Cells.

mBio
2020-07-07 | Journal article
DOI: 10.1128/mbio.00915-20
PMID: 32636244
PMC: PMC7343987
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii.

PLoS pathogens
2019-06-13 | Journal article
DOI: 10.1371/journal.ppat.1007746
PMID: 31194856
PMC: PMC6564765
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation.

mBio
2019-04-30 | Journal article
DOI: 10.1128/mbio.00381-19
PMID: 31040237
PMC: PMC6495372
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii.

Antimicrobial agents and chemotherapy
2018-10-24 | Journal article
DOI: 10.1128/aac.01442-18
PMID: 30181373
PMC: PMC6201070
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Translational Control in the Latency of Apicomplexan Parasites.

Trends in parasitology
2017-09-20 | Journal article
DOI: 10.1016/j.pt.2017.08.006
PMID: 28942109
PMC: PMC5705472
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Expression of non-acetylatable lysines 10 and 14 of histone H4 impairs transcription and replication in Trypanosoma cruzi.

Molecular and biochemical parasitology
2015-11-19 | Journal article
DOI: 10.1016/j.molbiopara.2015.11.001
PMID: 26602446
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Ikaros could be a key factor in the maintenance of "B-side" of B-1 cells.

Immunobiology
2015-06-19 | Journal article
DOI: 10.1016/j.imbio.2015.06.010
PMID: 26141488
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Characterization of Trypanosoma cruzi Sirtuins as Possible Drug Targets for Chagas Disease.

Antimicrobial agents and chemotherapy
2015-05-26 | Journal article
DOI: 10.1128/aac.04694-14
PMID: 26014945
PMC: PMC4505258
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

A membrane-bound eIF2 alpha kinase located in endosomes is regulated by heme and controls differentiation and ROS levels in Trypanosoma cruzi.

PLoS pathogens
2015-02-06 | Journal article
DOI: 10.1371/journal.ppat.1004618
PMID: 25658109
PMC: PMC4450062
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Oral exposure to Phytomonas serpens attenuates thrombocytopenia and leukopenia during acute infection with Trypanosoma cruzi.

PloS one
2013-07-02 | Journal article
DOI: 10.1371/journal.pone.0068299
PMID: 23844182
PMC: PMC3699546
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms.

PloS one
2011-11-16 | Journal article
DOI: 10.1371/journal.pone.0027904
PMID: 22114724
PMC: PMC3218062
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎

Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.

The Journal of biological chemistry
2010-05-21 | Journal article
DOI: 10.1074/jbc.m110.120212
PMID: 20495004
PMC: PMC2911323
Source: Self-asserted source
Leonardo Augusto
grade
Preferred source (of 2)‎
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