Personal information

Websites & social links

(Former) FAU HBOI Group Page
Github (Mostly Private)

Other IDs

ResearcherID: G-1445-2013

Keywords

cloud compute, genomics, bioinformatics, computational biology, hpc, big data, -omics, micr

Countries

United Kingdom, United States

Activities

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Employment (10)

Amazon Web Services Inc: London, GB

2021-07-04 to present | Worldwide Senior Solution Specialist Genomics
Employment
Source: Self-asserted source
Nick Dickens

Amazon Web Services EMEA: London, GB

2019-10 to 2021-07-04 | Specialist Solutions Architect (Genomics) (WWPS)
Employment
Source: Self-asserted source
Nick Dickens

Florida Atlantic University: Fort Pierce, Florida, US

2016-09 to 2019-10 | Associate Research Professor (Harbor Branch Oceanographic Institute)
Employment
Source: Self-asserted source
Nick Dickens

University of Glasgow: Glasgow, GB

2014-09 to 2016-09 | Bioinformatics Team Leader (Wellcome Trust Centre for Molecular Parasitology)
Employment
Source: Self-asserted source
Nick Dickens

University of Glasgow: Glasgow, GB

2012-11 to 2014-09 | Senior Bioinformatician (Wellcome Trust Centre for Molecular Parasitology)
Employment
Source: Self-asserted source
Nick Dickens

University of Glasgow: Glasgow, GB

2009-11 to 2012-11 | Bioinformatician (Post-Doc) (Wellcome Trust Centre for Molecular Parasitology)
Employment
Source: Self-asserted source
Nick Dickens

Institute of Cancer Research: Sutton, Surrey, GB

2006-11 to 2009-11 | Higher Scientific Officer (Bioinformatics Post-Doc) (Section of Haemato-Oncology)
Employment
Source: Self-asserted source
Nick Dickens

MRC Clinical Sciences Centre: London, GB

2005-05 to 2006-11 | Bioinformatician (Post-Doc) (Institute of Genetics and Molecular Medicine)
Employment
Source: Self-asserted source
Nick Dickens

MRC Functional Genetics Unit: Oxford, Oxfordshire, GB

2001-01 to 2002-01 | Bioinformatics Research Associate (Bioinformatics and Comparative Genomics)
Employment
Source: Self-asserted source
Nick Dickens

NV Organon: Oss, NL

2000-09 to 2001-01 | Bioinformatics Intern (Target Discovery Section)
Employment
Source: Self-asserted source
Nick Dickens

Education and qualifications (5)

AWS Certification: Seattle, WA, US

2021-04 to present | AWS Certified Solutions Architect - Professional (SVVT2R5L11VQQLKW)
Qualification
Source: Self-asserted source
Nick Dickens

AWS Certification: Seattle, WA, US

2020-10 to present | AWS Certified Developer - Associate (ZTCVQ8DJ2JBQQB9S)
Qualification
Source: Self-asserted source
Nick Dickens

AWS Certification: Seattle, WA, US

2020-06 to present | AWS Certified Solutions Architect - Associate (EFCXPZNCGN14QKCL)
Qualification
Source: Self-asserted source
Nick Dickens

University of Oxford: Oxford, GB

2002-01-01 to 2006-12-31 | DPhil Bioinformatics (Physiology Anatomy and Genetics)
Education
Source: Self-asserted source
Nick Dickens

Imperial College London: London, GB

1996-10-01 to 2000-07-01 | BSc Hons Applied Biology
Education
Source: Self-asserted source
Nick Dickens

Professional activities (4)

Florida Atlantic University Charles E Schmidt College of Science: Boca Raton, FL, US

2016-09 to present | Affiliate Associate Professor (unpaid) (Faculty)
Invited position
Source: Self-asserted source
Nick Dickens

Florida Atlantic University Harriet L Wilkes Honors College: Jupiter, FL, US

2017-09 to 2020-08 | Affiliate Associate Professor (unpaid) (Faculty)
Invited position
Source: Self-asserted source
Nick Dickens

FAU Harbor Branch Oceanographic Institute: Fort Pierce, FL, US

2018-04-01 to 2019-09-01 | Chair Faculty Assembly
Invited position
Source: Self-asserted source
Nick Dickens

FAU Harbor Branch Oceanographic Institute: Fort Pierce, FL, US

2017-09-01 to 2018-03-31 | Vice Chair Faculty Assembly
Invited position
Source: Self-asserted source
Nick Dickens

Funding (10)

Exploring the Blue Economy Biotechnology Potential of Deep-Water Habitats

2019-09-01 to 2021-08-31 | Grant
National Oceanic and Atmospheric Administration (Washington D.C., US)
URL: https://app.dimensions.ai/details/grant/grant.8661800
Part of GRANT_NUMBER:

NA19OAR0110302
Source: Self-asserted source
Nick Dickens

Genomics in Finfish Seedstocks (part of award)

2019-09 to 2024 | Award
U.S. Department of Agriculture (Washington, DC, US)
URL: https://www.fau.edu/newsdesk/articles/fau-usda-aquaculture.php
Source: Self-asserted source
Nick Dickens

Exploring Florida Whale Health in a Rapidly Changing Environment

2019-01 to 2019-12 | Grant
Florida Specialty License Plate Program (State of Florida, US)
Source: Self-asserted source
Nick Dickens

Biological and Molecular Functional Dynamics of Harmful Algal Blooms in Coastal Waters

2018-07 to 2019-06 | Grant
Harbor Branch Oceanographic Institute Foundation (Fort Pierce, Florida, US)
Source: Self-asserted source
Nick Dickens

CRACK-IT A multiscale model to minimise animal usage in leishmaniasis drug development (Phase 2)

2016-01 to 2019-01 | Grant
National Centre for the Replacement, Refinement and Reduction of Animals in Research (London, GB)
Source: Self-asserted source
Nick Dickens

Comparative transcriptomic analysis of central nervous system and bloodstream-resident trypanosomes in a murine model of human African sleeping sickness

2015-09 to 2017-04 | Grant
Wellcome Trust/University of Glasgow (London, GB)
Part of GRANT_NUMBER:

105614/Z/14/Z
Source: Self-asserted source
Nick Dickens

LeiSHield: A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries

2015-01 to 2015-12 | Grant
Institute Pasteur (Paris, FR)
Source: Self-asserted source
Nick Dickens

Using Bioinformatics Data Integration to Understand the Strategies Kinetoplastid Parasites Use for Diversification.

2014-10 to 2018-09 | Grant
EPSRC UK/Doctoral Training Centre in Cell and Proteomic Technologies (London, GB)
Part of GRANT_NUMBER:

EP/F500424/1
Source: Self-asserted source
Nick Dickens

The Cooperative Institute for Ocean Exploration, Research and Technology (CIOERT) Years 6-10

2014-07-01 to 2020-06-30 | Grant
National Oceanic and Atmospheric Administration (Washington D.C., US)
URL: https://app.dimensions.ai/details/grant/grant.4041537
Part of GRANT_NUMBER:

NA14OAR4320260
Source: Self-asserted source
Nick Dickens

Leishmania genome sequence diversity and disease tropism in Sudanese strains

2012-09 to 2014-03 | Grant
Wellcome Trust/University of Glasgow (London, GB)
Part of GRANT_NUMBER:

097821/Z/11/Z
Source: Self-asserted source
Nick Dickens

Works (45)

Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole

PLOS Neglected Tropical Diseases
2021-11-09 | Journal article
DOI: 10.1371/journal.pntd.0009939
Contributors: Pieter C. Steketee; Margaret A. Phillips; Federica Giordani; Isabel M. Vincent; Kathryn Crouch; Fiona Achcar; Nicholas J. Dickens; Liam J. Morrison; Annette MacLeod; Michael P. Barrett
Source: check_circle
Crossref

Defining the sediment prokaryotic communities of the Indian River Lagoon, FL, USA, an Estuary of National Significance.

PloS one
2020-10 | Journal article
DOI: 10.1371/journal.pone.0236305
PMID: 33105476
PMC: PMC7588086
Contributors: Bradshaw DJ; Dickens NJ; Trefry JH; McCarthy PJ
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Defining the sediment microbiome of the Indian River Lagoon, FL, USA, an Estuary of National Significance

2020-07 | Preprint
DOI: 10.1101/2020.07.07.191254
PPR: PPR184995
Contributors: Bradshaw DJ; Dickens NJ; Trefry JH; McCarthy PJ
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A

PLOS Pathogens
2020-05-28 | Journal article
DOI: 10.1371/journal.ppat.1008091
Contributors: Harshal Patil; Michael J. Blackman; Katie R. Hughes; Leandro Lemgruber; Nisha Philip; Nicholas Dickens; G. Lucas Starnes; Andrew. P. Waters
Source: check_circle
Crossref

Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens.

Cell reports
2020-01 | Journal article
DOI: 10.1016/j.celrep.2019.12.049
PMID: 31968257
PMC: PMC6988115
Contributors: Black JA; Crouch K; Lemgruber L; Lapsley C; Dickens N; Tosi LRO; Mottram JC; McCulloch R
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A

2019-10 | Other
DOI: 10.1101/811802
OTHER-ID:

PPR99136
Contributors: Patil H; Hughes K; Lemgruber L; Philip N; Dickens N; Waters AP
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.

PLoS neglected tropical diseases
2019-02 | Journal article
DOI: 10.1371/journal.pntd.0007052
PMID: 30716073
PMC: PMC6375703
Contributors: Pountain AW; Weidt SK; Regnault C; Bates PA; Donachie AM; Dickens NJ; Barrett MP
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

The ATR kinase of Trypanosoma brucei links DNA damage signalling and monoallelic control of surface antigen gene expression during antigenic variation

2018-10 | Other
DOI: 10.1101/435198
OTHER-ID:

PPR57637
Contributors: Black JA; Crouch K; Lemgruber L; Lapsley C; Dickens N; Mottram JC; McCulloch R
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis.

EBioMedicine
2018-09 | Journal article
DOI: 10.1016/j.ebiom.2018.09.029
PMID: 30268832
PMC: PMC6197651
Contributors: Carnielli JBT; Crouch K; Forrester S; Silva VC; Carvalho SFG; Damasceno JD; Brown E; Dickens NJ; Costa DL; Costa CHN et al.
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Sterol 14$α$-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

PLoS Neglected Tropical Diseases
2017 | Journal article
DOI: 10.1371/journal.pntd.0005649
PMID: 28622334
Part of ISBN: 1111111111
Source: Self-asserted source
Nick Dickens

Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity

Infection, Genetics and Evolution
2016 | Journal article
DOI: 10.1016/j.meegid.2016.10.029
Source: Self-asserted source
Nick Dickens

Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation

eLife
2016-05 | Journal article
DOI: 10.7554/eLife.12765
Source: Self-asserted source
Nick Dickens

Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe

Genome Biology
2015 | Journal article
DOI: 10.1186/s13059-015-0788-9
Source: Self-asserted source
Nick Dickens

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.

Nature
2014 | Journal article
DOI: 10.1038/nature12970
PMID: 24572359
ISBN:

1476-4687 (Electronic) 0028-0836 (Linking)
Source: Self-asserted source
Nick Dickens

Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen

PLoS Pathogens
2014 | Journal article
DOI: 10.1371/journal.ppat.1003886
PMID: 24453978
Source: Self-asserted source
Nick Dickens

The comparative genomics and phylogenomics of Leishmania amazonensis parasite

Evolutionary Bioinformatics
2014 | Journal article
DOI: 10.4137/EBO.S13759
Source: Self-asserted source
Nick Dickens

The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic Kinetoplastids Reveals a Parasite Tailored for Plants

PLoS Genetics
2014 | Journal article
DOI: 10.1371/journal.pgen.1004007
PMID: 24516393
Source: Self-asserted source
Nick Dickens

Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei

Cell Rep
2012 | Journal article
DOI:

10.1016/j.celrep.2012.06.007

Part of ISSN:

2211-1247
Contributors: Tiengwe, C.; Marcello, L.; Farr, H.; Dickens, N.; Kelly, S.; Swiderski, M.; Vaughan, D.; Gull, K.; Barry, J. D.; Bell, S. D. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

Genome Res
2011 | Journal article
DOI:

10.1101/gr.122945.111

Part of ISSN:

1549-5469
Contributors: Rogers, M. B.; Hilley, J. D.; Dickens, N. J.; Wilkes, J.; Bates, P. A.; Depledge, D. P.; Harris, D.; Her, Y.; Herzyk, P.; Imamura, H. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma

J Clin Oncol
2011 | Journal article
DOI:

10.1200/JCO.2010.28.0792

Part of ISSN:

1527-7755
Contributors: Johnson, D. C.; Corthals, S. L.; Walker, B. A.; Ross, F. M.; Gregory, W. M.; Dickens, N. J.; Lokhorst, H. M.; Goldschmidt, H.; Davies, F. E.; Durie, B. G. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

Blood
2010 | Journal article
DOI:

10.1182/blood-2010-04-279596

Part of ISSN:

1528-0020
Contributors: Walker, B. A.; Leone, P. E.; Chiecchio, L.; Dickens, N. J.; Jenner, M. W.; Boyd, K. D.; Johnson, D. C.; Gonzalez, D.; Dagrada, G. P.; Protheroe, R. K. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

EP2356255A2.pdf

2010 | Other
Source: Self-asserted source
Nick Dickens

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

Clin Cancer Res
2010 | Journal article
DOI:

10.1158/1078-0432.CCR-09-2831

Part of ISSN:

1078-0432
Contributors: Dickens, N. J.; Walker, B. A.; Leone, P. E.; Johnson, D. C.; Brito, J. L.; Zeisig, A.; Jenner, M. W.; Boyd, K. D.; Gonzalez, D.; Gregory, W. M. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

Blood
2010 | Journal article
DOI: 10.1182/blood-2010-01-263236
PMID: 20421453
Part of ISBN:

0006-4971
Source: Self-asserted source
Nick Dickens
grade
Preferred source (of 2)‎

MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

Haematologica
2009 | Journal article
DOI:

10.3324/haematol.13426

Part of ISSN:

1592-8721
Contributors: Brito, J. L.; Walker, B.; Jenner, M.; Dickens, N. J.; Brown, N. J.; Ross, F. M.; Avramidou, A.; Irving, J. A.; Gonzalez, D.; Davies, F. E. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

US20110301055.pdf

2009 | Other
Source: Self-asserted source
Nick Dickens

Methods for determining a prognosis in Multiple Myeloma

2009-12-04 | Patent
OTHER-ID:

PCT/GB2009/002815
Source: Self-asserted source
Nick Dickens

Deletions of CDKN2C in multiple myeloma: biological and clinical implications

Clin Cancer Res
2008 | Journal article
DOI:

10.1158/1078-0432.CCR-08-0347

Part of ISSN:

1078-0432
Contributors: Leone, P. E.; Walker, B. A.; Jenner, M. W.; Chiecchio, L.; Dagrada, G.; Protheroe, R. K.; Johnson, D. C.; Dickens, N. J.; Brito, J. L.; Else, M. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping Associations Thalidomide Mediated Venous Thrombotic Events in Myeloma Identified using Targeted Genotyping

Hematology
2008 | Journal article
DOI: 10.1182/blood-2008-02-140434
Source: Self-asserted source
Nick Dickens
grade
Preferred source (of 2)‎

Genome-wide co-expression analysis in multiple tissues

PLoS One
2008 | Journal article
DOI:

10.1371/journal.pone.0004033

Part of ISSN:

1932-6203
Contributors: Grieve, I. C.; Dickens, N. J.; Pravenec, M.; Kren, V.; Hubner, N.; Cook, S. A.; Aitman, T. J.; Petretto, E.; Mangion, J.
Source: Self-asserted source
Nick Dickens via ResearcherID

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

Blood
2007 | Journal article
DOI:

10.1182/blood-2007-02-075069

Part of ISSN:

0006-4971
Contributors: Jenner, M. W.; Leone, P. E.; Walker, B. A.; Ross, F. M.; Johnson, D. C.; Gonzalez, D.; Chiecchio, L.; Dachs Cabanas, E.; Dagrada, G. P.; Nightingale, M. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

eQTL Explorer: integrated mining of combined genetic linkage and expression experiments

Bioinformatics
2006 | Journal article
DOI:

10.1093/bioinformatics/btk007

Part of ISSN:

1367-4803
Contributors: Mueller, M.; Goel, A.; Thimma, M.; Dickens, N. J.; Aitman, T. J.; Mangion, J.
Source: Self-asserted source
Nick Dickens via ResearcherID

Heritability and tissue specificity of expression quantitative trait loci

PLoS Genet
2006 | Journal article
DOI:

10.1371/journal.pgen.0020172

Part of ISSN:

1553-7404
Contributors: Petretto, E.; Mangion, J.; Dickens, N. J.; Cook, S. A.; Kumaran, M. K.; Lu, H.; Fischer, J.; Maatz, H.; Kren, V.; Pravenec, M. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

Nature
2004 | Journal article
DOI:

10.1038/nature03154

Part of ISSN:

1476-4687
Contributors: International Chicken Genome Sequencing Consortium
Source: Self-asserted source
Nick Dickens via ResearcherID

Positional cloning of a novel gene influencing asthma from chromosome 2q14

Nat Genet
2003 | Journal article
DOI:

10.1038/ng1256

Part of ISSN:

1061-4036
Contributors: Allen, M.; Heinzmann, A.; Noguchi, E.; Abecasis, G.; Broxholme, J.; Ponting, C. P.; Bhattacharyya, S.; Tinsley, J.; Zhang, Y.; Holt, R. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

Trends Biochem Sci
2003 | Journal article
DOI:

10.1016/S0968-0004(03)00004-5

Part of ISSN:

0968-0004
Contributors: Maurer-Stroh, S.; Dickens, N. J.; Hughes-Davies, L.; Kouzarides, T.; Eisenhaber, F.; Ponting, C. P.
Source: Self-asserted source
Nick Dickens via ResearcherID

THoR: a tool for domain discovery and curation of multiple alignments

Genome Biol
2003 | Journal article
DOI:

10.1186/gb-2003-4-8-r52

Part of ISSN:

1465-6914
Contributors: Dickens, N. J.; Ponting, C. P.
Source: Self-asserted source
Nick Dickens via ResearcherID

Cadherin-like domains in alpha-dystroglycan, alpha/epsilon-sarcoglycan and yeast and bacterial proteins

Curr Biol
2002 | Journal article
Part of ISSN:

0960-9822
Contributors: Dickens, N. J.; Beatson, S.; Ponting, C. P.
Source: Self-asserted source
Nick Dickens via ResearcherID

Initial sequencing and comparative analysis of the mouse genome

Nature
2002 | Journal article
DOI:

10.1038/nature01262

Part of ISSN:

0028-0836
Contributors: Waterston, R. H.; Lindblad-Toh, K.; Birney, E.; Rogers, J.; Abril, J. F.; Agarwal, P.; Agarwala, R.; Ainscough, R.; Alexandersson, M.; An, P. et al.
Source: Self-asserted source
Nick Dickens via ResearcherID

Recent improvements to the SMART domain-based sequence annotation resource

Nucleic Acids Res
2002 | Journal article
Part of ISSN:

1362-4962
Contributors: Letunic, I.; Goodstadt, L.; Dickens, N. J.; Doerks, T.; Schultz, J.; Mott, R.; Ciccarelli, F.; Copley, R. R.; Ponting, C. P.; Bork, P.
Source: Self-asserted source
Nick Dickens via ResearcherID

Cadherin-like domains in alpha-dystroglycan, alpha/epsilon-sarcoglycan and yeast and bacterial proteins.

Current biology : CB
2002-03 | Journal article
DOI: 10.1016/s0960-9822(02)00748-0
PMID: 11909544
Contributors: Dickens NJ; Beatson S; Ponting CP
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Recent improvements to the SMART domain-based sequence annotation resource.

Nucleic acids research
2002-01 | Journal article
DOI: 10.1093/nar/30.1.242
PMID: 11752305
PMC: PMC99073
Contributors: Letunic I; Goodstadt L; Dickens NJ; Doerks T; Schultz J; Mott R; Ciccarelli F; Copley RR; Ponting CP; Bork P
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Genome cartography through domain annotation

Genome Biol
2001 | Journal article
Part of ISSN:

1465-6914
Contributors: Ponting, C. P.; Dickens, N. J.
Source: Self-asserted source
Nick Dickens via ResearcherID

Genome cartography through domain annotation.

Genome biology
2001-01 | Journal article
DOI: 10.1186/gb-2001-2-7-comment2006
PMID: 11521679
Contributors: Ponting CP; Dickens NJ
Source: Self-asserted source
Nick Dickens via Europe PubMed Central

Genome cartography through domain annotation

Genome biology
2001-01 | Journal article
PMC: PMC139413
Contributors: Ponting C; Dickens N
Source: Self-asserted source
Nick Dickens via Europe PubMed Central
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