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Tetraenone A: A New β-Ionone Derivative from <i>Tetraena aegyptia</i>

Metabolites
2023-12 | Journal article | Author
DOI: 10.3390/metabo13121202
Contributors: Ahmed Ashour; Asmaa E. Sherif; Selwan M. El-Sayed; Ji-Young Kim; Dae Sik Jang; Abtin Anvari; Abdelbasset Farahat; Sabrin R.M. Ibrahim; Gamal A. Mohamed; Bayan E. Ainousah et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

A Novel Hydroxyapatite/Vitamin B<sub>12</sub> Nanoformula for Treatment of Bone Damage: Preparation, Characterization, and Anti-Arthritic, Anti-Inflammatory, and Antioxidant Activities in Chemically Induced Arthritic Rats

Pharmaceuticals
2023-04 | Journal article | Author
DOI: 10.3390/ph16040551
Contributors: Amany Belal; Rehab Mahmoud; Eman E. Mohamed; Ahmed Farghali; Fatma Ibrahim Abo El-Ela; Amr Gamal; Fatma Mohamed Halfaya; Esraa Khaled; Abdelbasset Farahat; Ahmed Hassan et al.
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Multidisciplinary Digital Publishing Institute

A modular design for minor groove binding and recognition of mixed base pair sequences of DNA

Chemical Communications
2017 | Journal article
DOI: 10.1039/c7cc06246j
EID:

2-s2.0-85029612065
Contributors: Guo, P.; Paul, A.; Kumar, A.; Harika, N.K.; Wang, S.; Farahat, A.A.; Boykin, D.W.; Wilson, W.D.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties

European Journal of Medicinal Chemistry
2017 | Journal article
DOI: 10.1016/j.ejmech.2017.01.037
EID:

2-s2.0-85012237677
Contributors: Farahat, A.A.; Kumar, A.; Say, M.; Wenzler, T.; Brun, R.; Paul, A.; Wilson, W.D.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

European Journal of Medicinal Chemistry
2017 | Journal article
DOI: 10.1016/j.ejmech.2017.10.056
EID:

2-s2.0-85032984013
Contributors: Farahat, A.A.; Ismail, M.A.; Kumar, A.; Wenzler, T.; Brun, R.; Paul, A.; Wilson, W.D.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Drug Design, Development and Therapy
2017 | Journal article
DOI: 10.2147/DDDT.S120618
EID:

2-s2.0-85017210271
Contributors: da Silva, C.F.; Batista, D.G.J.; de Araújo, J.S.; Cunha-Junior, E.F.; Stephens, C.E.; Banerjee, M.; Farahat, A.A.; Akay, S.; Fisher, M.K.; Boykin, D.W. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis and antimicrobial activity of some novel substituted 3-(Thiophen-2-yl)pyrazole-Based heterocycles

Letters in Drug Design and Discovery
2017 | Journal article
DOI: 10.2174/1570180814666170327162447
EID:

2-s2.0-85032938086
Contributors: Abdel-Wahab, B.F.; Farahat, A.A.; Awad, G.E.A.; El-Hiti, G.A.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds

Saudi Pharmaceutical Journal
2017 | Journal article
DOI: 10.1016/j.jsps.2017.02.003
EID:

2-s2.0-85013059474
Contributors: Morsy, S.A.; Farahat, A.A.; Nasr, M.N.A.; Tantawy, A.S.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthetic profile of thiadiazoloquinazolines

Phosphorus, Sulfur and Silicon and the Related Elements
2017 | Journal article
DOI: 10.1080/10426507.2017.1354213
EID:

2-s2.0-85031096550
Contributors: Abdel-Wahab, B.F.; Farahat, A.A.; Bekheit, M.S.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Systematic synthetic and biophysical development of mixed sequence DNA binding agents

Organic and Biomolecular Chemistry
2017 | Journal article
DOI: 10.1039/c6ob02390h
EID:

2-s2.0-85010685648
Contributors: Paul, A.; Kumar, A.; Nanjunda, R.; Farahat, A.A.; Boykin, D.W.; Wilson, W.D.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Understanding Chemistry and Unique NMR Characters of Novel Amide and Ester Leflunomide Analogues

Magnetochemistry
2017-12 | Journal article
DOI: 10.3390/magnetochemistry3040041
Source: check_circle
Multidisciplinary Digital Publishing Institute

Investigation of the electrostatic and hydration properties of DNA minor groove-binding by a heterocyclic diamidine by osmotic pressure

Biophysical Chemistry
2016 | Journal article
DOI: 10.1016/j.bpc.2017.02.008
EID:

2-s2.0-85016556276
Contributors: Erlitzki, N.; Huang, K.; Xhani, S.; Farahat, A.A.; Kumar, A.; Boykin, D.W.; Poon, G.M.K.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Pharmacologic efficacy of PU.1 inhibition by heterocyclic dications: A mechanistic analysis

Nucleic Acids Research
2016 | Journal article
DOI: 10.1093/nar/gkw229
EID:

2-s2.0-84970016210
Contributors: Stephens, D.C.; Kim, H.M.; Kumar, A.; Farahat, A.A.; Boykin, D.W.; K Poon, G.M.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Phenotypic screening in vitro of novel aromatic amidines against Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy
2016 | Journal article
DOI: 10.1128/AAC.01788-15
EID:

2-s2.0-84979555896
Contributors: Simões-Silva, M.R.; Nefertiti, A.S.G.; De Araújo, J.S.; Batista, M.M.; Da Silva, P.B.; Bahia, M.T.; Menna-Barreto, R.S.; Pavão, B.P.; Green, J.; Farahat, A.A. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis and in vivo antifibrotic activity of novel leflunomide analogues

Letters in Drug Design and Discovery
2016 | Journal article
DOI: 10.2174/1570180813666160630125624
EID:

2-s2.0-84992187688
Contributors: Hamdi, A.; Said, E.; Farahat, A.A.; El-Bialy, S.A.A.; Massoud, M.A.M.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

Bioorganic and Medicinal Chemistry Letters
2016 | Journal article
DOI: 10.1016/j.bmcl.2016.03.082
EID:

2-s2.0-84978066139
Contributors: Zhu, X.; Farahat, A.A.; Mattamana, M.; Joice, A.; Pandharkar, T.; Holt, E.; Banerjee, M.; Gragg, J.L.; Hu, L.; Kumar, A. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI

Bioorganic and Medicinal Chemistry Letters
2016 | Journal article
DOI: 10.1016/j.bmcl.2016.11.006
EID:

2-s2.0-84997706228
Contributors: Farahat, A.A.; Bennett-Vaughn, C.; Mineva, E.M.; Kumar, A.; Wenzler, T.; Brun, R.; Liu, Y.; Wilson, W.D.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthetic Routes to Pyrazole-3(5)-carboxylates

Journal of Heterocyclic Chemistry
2016 | Journal article
DOI: 10.1002/jhet.1504
EID:

2-s2.0-84956748434
Contributors: Khidre, R.E.; Abdel-Wahab, B.F.; Farahat, A.A.; Mohamed, H.A.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthetic routes to thiazoloquinazolines

Chemistry of Heterocyclic Compounds
2016 | Journal article
DOI: 10.1007/s10593-016-1961-0
EID:

2-s2.0-84996486412
Contributors: Bekheit, M.S.; Farahat, A.A.; Abdel-Wahab, B.F.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

The Thiophene “Sigma-Hole” as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove

Chemistry - A European Journal
2016 | Journal article
DOI: 10.1002/chem.201603422
EID:

2-s2.0-84987650396
Contributors: Guo, P.; Paul, A.; Kumar, A.; Farahat, A.A.; Kumar, D.; Wang, S.; Boykin, D.W.; Wilson, W.D.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Copper(I) 3-methylsalicylate mediates the Chan-Lam N-arylation of heterocycles

Synthetic Communications
2015 | Journal article
DOI: 10.1080/00397911.2014.961196
EID:

2-s2.0-84945178359
Contributors: Farahat, A.A.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Resolution of mixed site DNA complexes with dimer-forming minor-groove binders by using electrospray ionization mass spectrometry: Compound structure and DNA sequence effects

Chemistry - A European Journal
2015 | Journal article
DOI: 10.1002/chem.201406322
EID:

2-s2.0-84925141900
Contributors: Laughlin, S.; Wang, S.; Kumar, A.; Farahat, A.A.; Boykin, D.W.; Wilson, W.D.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Copper(I) 3-methylsalicylate, an efficient catalyst for N-arylation of heterocycles under moderate reaction conditions

Tetrahedron Letters
2014 | Journal article
DOI: 10.1016/j.tetlet.2014.03.117
EID:

2-s2.0-84899642998
Contributors: Farahat, A.A.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

In vitro and in vivo studies of the biological activity of novel arylimidamides against Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy
2014 | Journal article
DOI: 10.1128/AAC.01403-13
EID:

2-s2.0-84903219297
Contributors: De Araújo, J.S.; Da Silva, C.F.; Batista, D.G.J.; Da Silva, P.B.; Meuser, M.B.; Aiub, C.A.F.; Da Silva, M.F.V.; Araújo-Lima, C.F.; Banerjee, M.; Farahat, A.A. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi

Parasitology
2014 | Journal article
DOI: 10.1017/S0031182014000407
EID:

2-s2.0-84920512101
Contributors: Timm, B.L.; Da Silva, P.B.; Batista, M.M.; Farahat, A.A.; Kumar, A.; Boykin, D.W.; Soeiro, M.N.C.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Structure-dependent binding of arylimidamides to the DNA minor groove

ChemBioChem
2014 | Journal article
DOI: 10.1002/cbic.201300622
EID:

2-s2.0-84890805530
Contributors: Chai, Y.; Munde, M.; Kumar, A.; Mickelson, L.; Lin, S.; Campbell, N.H.; Banerjee, M.; Akay, S.; Liu, Z.; Farahat, A.A. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines

Nucleic Acids Research
2014 | Journal article
DOI: 10.1093/nar/gkt955
EID:

2-s2.0-84893306183
Contributors: Munde, M.; Wang, S.; Kumar, A.; Stephens, C.E.; Farahat, A.A.; Boykin, D.W.; Wilson, W.D.; Poon, G.M.K.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine

Biochemistry
2014 | Journal article
DOI: 10.1021/bi401582t
EID:

2-s2.0-84896836233
Contributors: Munde, M.; Kumar, A.; Peixoto, P.; Depauw, S.; Ismail, M.A.; Farahat, A.A.; Paul, A.; Say, M.V.; David-Cordonnier, M.-H.; Boykin, D.W. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

4-Dimethylamino-1-(4-methoxyphenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3- carbonitrile

Acta Crystallographica Section E: Structure Reports Online
2013 | Journal article
DOI: 10.1107/S1600536813004893
EID:

2-s2.0-84874869014
Contributors: Abdel-Wahab, B.F.; Mohamed, H.A.; Farahat, A.A.; Ng, S.W.; Tiekink, E.R.T.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Facile synthesis of aryl-pyridyl, pyridazinyl, pyrazinyl, and triazinyl acetonitriles

Journal of Heterocyclic Chemistry
2013 | Journal article
DOI: 10.1002/jhet.1535
EID:

2-s2.0-84878435809
Contributors: Farahat, A.A.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

Nucleic Acids Research
2013 | Journal article
DOI: 10.1093/nar/gks971
EID:

2-s2.0-84871748962
Contributors: Nhili, R.; Peixoto, P.; Depauw, S.; Flajollet, S.; Dezitter, X.; Munde, M.M.; Ismail, M.A.; Kumar, A.; Farahat, A.A.; Stephens, C.E. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

2-Chloroquinoline-3-carbaldehydes: Synthesis, reactionsand applications

Arkivoc
2012 | Journal article
EID:

2-s2.0-84866934600
Contributors: Abdel-Wahab, B.F.; Khidre, R.E.; Farahat, A.A.; El-AhI, A.-A.S.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships

Bioorganic and Medicinal Chemistry Letters
2012 | Journal article
DOI: 10.1016/j.bmcl.2012.06.037
EID:

2-s2.0-84867873428
Contributors: Reid, C.S.; Farahat, A.A.; Zhu, X.; Pandharkar, T.; Boykin, D.W.; Werbovetz, K.A.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: In vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies

Antimicrobial Agents and Chemotherapy
2012 | Journal article
DOI: 10.1128/AAC.06404-11
EID:

2-s2.0-84862569242
Contributors: Zhu, X.; Liu, Q.; Yang, S.; Parman, T.; Green, C.E.; Mirsalis, J.C.; Soeiro, M.D.N.C.; De Souza, E.M.; Da Silva, C.F.; Batista, D.D.G.J. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents

Current Pharmaceutical Design
2012 | Journal article
DOI: 10.2174/138161212799958422
EID:

2-s2.0-84860198232
Contributors: Nanjunda, R.; Musetti, C.; Kumar, A.; Ismail, M.A.; Farahat, A.A.; Wang, S.; Sissi, C.; Palumbo, M.; Boykin, D.W.; Wilson, W.D.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form - DB1965 - against Trypanosoma cruzi infection

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0030356
EID:

2-s2.0-84856116592
Contributors: da Silva, C.F.; Batista, D.G.J.; Oliveira, G.M.; de Souza, E.M.; Hammer, E.R.; da Silva, P.B.; Daliry, A.; Araujo, J.S.; Britto, C.; Rodrigues, A.C.M. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Suzuki-Miyaura coupling reactions of 3,5-dichloro-1,2,4-thiadiazole

Heterocycles
2012 | Journal article
DOI: 10.3987/COM-12-12533
EID:

2-s2.0-84866662305
Contributors: Farahat, A.A.; Boykina, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis and antiviral activity of benzimidazolyl-and triazolyl-1,3,5- triazines

Medicinal Chemistry Research
2012 | Journal article
DOI: 10.1007/s00044-011-9574-8
EID:

2-s2.0-84861907791
Contributors: Maarouf, A.R.; Farahat, A.A.; Selim, K.B.; Eisa, H.M.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides

European Journal of Medicinal Chemistry
2012 | Journal article
DOI: 10.1016/j.ejmech.2012.06.058
EID:

2-s2.0-84865777343
Contributors: Banerjee, M.; Farahat, A.A.; Kumar, A.; Wenzler, T.; Brun, R.; Munde, M.M.; Wilson, W.D.; Zhu, X.; Werbovetz, K.A.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Unusual regioselective reactions of 2,4-bis(methylsulfanyl)pyrimidine under modified suzuki and stille cross-coupling conditions

Synthesis
2012 | Journal article
DOI: 10.1055/s-0031-1289615
EID:

2-s2.0-84655161531
Contributors: Farahat, A.A.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Exploration of larger central ring linkers in furamidine analogues: Synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties

Bioorganic and Medicinal Chemistry
2011 | Journal article
DOI: 10.1016/j.bmc.2011.02.045
EID:

2-s2.0-79953222151
Contributors: Farahat, A.A.; Paliakov, E.; Kumar, A.; Barghash, A.-E.M.; Goda, F.E.; Eisa, H.M.; Wenzler, T.; Brun, R.; Liu, Y.; Wilson, W.D. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Induced topological changes in DNA complexes: Influence of DNA sequences and small molecule structures

Nucleic Acids Research
2011 | Journal article
DOI: 10.1093/nar/gkq1362
EID:

2-s2.0-79959898511
Contributors: Hunt, R.A.; Munde, M.; Kumar, A.; Ismail, M.A.; Farahat, A.A.; Arafa, R.K.; Say, M.; Batista-Parra, A.; Tevis, D.; Boykin, D.W. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Pyrazole-3(4)-carbaldehyde: Synthesis, reactions and biological activity

Arkivoc
2011 | Journal article
EID:

2-s2.0-79960386118
Contributors: Abdel-Wahab, B.F.; Khidre, R.E.; Farahat, A.A.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Synthetic accesses to azolylthiazoles

Heterocycles
2011 | Journal article
DOI: 10.3987/REV-11-717
EID:

2-s2.0-84055212358
Contributors: Abdel-Wahab, B.F.; Mohamed, H.A.; Farahat, A.A.; Dawood, K.M.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro

Parasitology
2011 | Journal article
DOI: 10.1017/S0031182011001429
EID:

2-s2.0-84862530700
Contributors: Da Silva, C.F.; Daliry, A.; Da Silva, P.B.; Akay, S.; Banerjee, M.; Farahat, A.A.; Fisher, M.K.; Hu, L.; Kumar, A.; Liu, Z. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA

Antimicrobial Agents and Chemotherapy
2011 | Journal article
DOI: 10.1128/AAC.00229-11
EID:

2-s2.0-80052834047
Contributors: Daliry, A.; Pires, M.Q.; Silva, C.F.; Pacheco, R.S.; Munde, M.; Stephens, C.E.; Kumar, A.; Ismail, M.A.; Liu, Z.; Farahat, A.A. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Water-mediated binding of agents that target the DNA minor groove

Journal of the American Chemical Society
2011 | Journal article
DOI: 10.1021/ja202006u
EID:

2-s2.0-79959864191
Contributors: Liu, Y.; Kumar, A.; Depauw, S.; Nhili, R.; David-Cordonnier, M.-H.; Lee, M.P.; Ismail, M.A.; Farahat, A.A.; Say, M.; Chackal-Catoen, S. et al.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

1H-benzimidazole-2-acetonitriles as synthon in fused benzimidazole synthesis

Journal of Heterocyclic Chemistry
2010 | Journal article
DOI: 10.1002/jhet.293
EID:

2-s2.0-77950332469
Contributors: Dawood, K.M.; Elwan, N.M.; Farahat, A.A.; Abdel-Wahab, B.F.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

2-Amino-4-thiazolidinones: Synthesis and reactions

Journal of Sulfur Chemistry
2010 | Journal article
DOI: 10.1080/17415993.2010.482155
EID:

2-s2.0-77955592811
Contributors: Metwally, M.A.; Farahat, A.A.; Abdel-Wahab, B.F.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier

Bichalcophenes: A concise synthesis of formyl ester- and cyano ester-substituted bithiophenes, bifurans, and furanothiophenes

Journal of Heterocyclic Chemistry
2010 | Journal article
DOI: 10.1002/jhet.295
EID:

2-s2.0-76149134124
Contributors: Farahat, A.A.; Kumar, A.; Barghash, A.E.-D.M.; Goda, F.E.; Eisa, H.M.; Boykin, D.W.
Source: Self-asserted source
Abdelbasset Farahat via Scopus - Elsevier
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Peer review (4 reviews for 3 publications/grants)

Review activity for Archiv der Pharmazie. (1)
Review activity for European journal of medicinal chemistry. (2)
Review activity for Results in chemistry. (1)
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