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Nanocarriers, Drug delivery, Biocatalysis, Bioseparation, Bioinformatic
Portugal

Biography

Dragana P C de Barros graduated in Biochemical Engineering and Biotechnology by University of Belgrade, Serbia. After graduation she was working around 5 years as an engineer in industry, first in the R&D Department and later on in the part of the Preparation and Manufacture Department. She decided to move to scientific research and in 2010 she completed her PhD in Biotechnology at Instituto Superior Tecnico (IST), Technical University of Lisbon, Portugal, having during her PhD studies trainees at University of Ulm, Germany, and collaboration with the Max-Planck Institute, Mainz, Germany. She developed environmentally friendly and multifunctional biphasic system (miniemulsion) for biosynthesis of aroma products, including bioprocess optimization studies, the protein and media engineering, optimization of reactions parameters, and reaction stability. After PhD she gain the postdoctoral project in Institute for Bioenginering and Bioscience, Instituto Superior Técnico (iBB/IST), and Molecular Simulation Laboratory, Instituto de Tecnologia Química e Biológica , Universidade Nova (MSL-ITQB/NOVA). During her work at ITQB/NOVA she developed a new semi-empirical model based on continuous electrostatic to study partition behaviour of therapeutic and industrial proteins in alternative purification systems (biphasic systems).
By finishing postdoctoral contract she stay one school year as an invited researcher in Department of Bioengineering, Instituto Superior Técnico, working also as a research scientist in iBB/IST. During 6 month (2016) of advanced scientific training in MaxSynBio research project (Max Planck Institute, Mainz, Germany) she developed a novel surface functionalized silica nano- and micro-structured capsule to capture bioactive compounds.
She also has 4 months’ professional experience (https://phdtrials.com/ , 2016) in clinical assessment of safety and efficacy of more than 50 commercial products and raw materials of Cosmetics products (in Spirit of Good Clinical Practices- GCP), for several clients (some of them from Fortune Global 500).
Currently she is research scientist, member of Biomolecular Diagnostic Laboratory at the ITQB NOVA, with the scientific interest including the crossover between experimental and modelling studies in the area of bioprocess and cutaneous drug delivery systems development. Present research interests involve applications of miniemulsions system in dermal drug delivery systems such as biodegradable nanostructured lipid carriers. In this context she is developing a novel naturally based lipid carriers with antimicrobial and antitumoral activity.
During her scientific career she also managed laboratory functions including organization and maintenance of lab space and equipment. Also participate in a training of Masters and PhD students in analytic techniques related with particles, protein and final product analysis. Participated in Master’s Examination Committees and as the invited referee for international peer –reviewed journals, show solid verbal and written communication skills.
Barros co-supervised 2 PhD theses in the area of lipid nanocarriers synthesis for bioactive compounds delivery and biopolymers synthesis using biocatalysts using miniemulsion technique. She also co-supervised 2 MSc theses in the area of protein separation in biphasic system as a part of the European Project INTENSO (FP7-KBBE-2012- 6). DPC de Barros published more than 20 peer-reviewed scientific papers, also has various communications published in the context of academic conferences, and numerous oral and poster communications. She published 2 book chapters in the area of nanoparticles engineering, biocompatibility and nanotoxicology in safety assessment of nanomaterials. Her wide experience in project managing as a team member in 5 national and international research projects was supported by Project Management course in 2020 by NOVA Doctoral School. As a team member she was involved in transfer technology programs such as COHiTEC-2007 program (http://antigo.cotecportugal.pt/en/), the ISCTE-IUL-MIT Venture Competition (www.mitportugal-iei.org/), and HiSeedTech-2018 program (http://hiseedtech.com/#header) .

Activities

Employment (4)

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica: Oeiras, Lisboa, PT

2018-07-01 to present | Reasercher
Employment
Source: Self-asserted source
Dragana P C de Barros

Instituto Superior Técnico, Univeresidade Lisboa: Lisboa, Lisboa, PT

2010-01-01 to 2018-06-30 | Postdoctoral Researcher (IBB -Institute for Bioengineering and Bioscience)
Employment
Source: Self-asserted source
Dragana P C de Barros

Universidade de Lisboa Instituto Superior Técnico: Lisboa, Lisboa, PT

2006 to 2010 | PhD student (Department of Bioengineering)
Employment
Source: Self-asserted source
Dragana P C de Barros

FIP “Grmec”-NOVOLINE : Belgrade, RS

1999 to 2004 | Engineer (Development and Research Department )
Employment
Source: Self-asserted source
Dragana P C de Barros

Funding (9)

Institute for Bioengineering and Biosciences

2019-01-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UID/BIO/04565/2019

Source: check_circle
CIÊNCIAVITAE

Untitled

2018-07-01 to 2024-06-30 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

DL 57/2016/CP1369/CT0006

Source: check_circle
CIÊNCIAVITAE

Aqueous two phase separation and electrically induced extraction as an integrated technological platform for proteins purification

2016-06 to 2017-11 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

iBB/2016/03

Source: check_circle
CIÊNCIAVITAE

(R, S)- Resolution-Separation of secondary alcohols by enzymatic miniemulsion technology

2012-03-01 to 2015-07-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/QUI-QUI/119210/2010

Source: check_circle
CIÊNCIAVITAE

GLYMAT: Synthesis of glycerol-based materials by cutinase using an integrated biocatalyst design process

2011-07-01 to 2013-09-30 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

ERA-Eula/0001/2009

Source: check_circle
CIÊNCIAVITAE

Protein-Aqueous Environment Interactions

2011-01-01 to 2013-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/EQU-EQU/112812/2009

Source: check_circle
CIÊNCIAVITAE

Predicting the partitioning coefficients of biomolecules in aqueos two phase system

2011 to 2016 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BPD/70409/2010

Source: check_circle
CIÊNCIAVITAE

Enzyme encapsulation

2007-09 to 2007-12 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

COST-STSM-865-02962

Source: check_circle
CIÊNCIAVITAE

Aroma ester synthesis using cutinase: a case study of an integrated biocatalyst design

2006-01 to 2010-07 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BD/24703/2005

Source: check_circle
CIÊNCIAVITAE

Peer review (7 reviews for 5 publications/grants)

Review activity for Biotechnology letters. (1)
Review activity for Biotechnology letters. (1)
Review activity for Chemical papers. (2)
Review activity for Journal of chemical technology and biotechnology. (2)
Review activity for Journal of microencapsulation (1)