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ethnbotany, medicinal plants, microbiology, biological activity, pharmacology
Morocco

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Education and qualifications (2)

Sidi Mohamed Ben Abdellah University: Fes, MA

2019 to present | PhD student ( Faculty of Science and Technology Fez)
Education
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Naoufal El Hachlafi

Sidi Mohamed Ben Abdellah University: Fes, MA

2017-09 to 2019-07 | Master's Degree in Sciences and Techniques in Microbial Biotechnology ( Faculty of Science and Technology Fez)
Education
Source: Self-asserted source
Naoufal El Hachlafi

Works (45)

Biochemical insights into specialized plant metabolites: Advancing cosmeceutical applications for skin benefits

Journal of Agriculture and Food Research
2025-03 | Journal article
Contributors: Amine Elbouzidi; Mounir Haddou; Abdellah Baraich; Mohamed Taibi; Naoufal El Hachlafi; Ashutosh Pareek; François Mesnard; Mohamed Addi
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Mixture design as an innovative tool to optimize the antioxidant and antibacterial activity of moroccan essential oils: Clinopodium nepeta, Ruta montana, and Dittrichia viscosa

Kuwait Journal of Science
2025-01 | Journal article
Contributors: Nesrine Benkhaira; Mouhcine Fadil; Naoufal El Hachlafi; Rachid Flouchi; Mohammed Lachkar; Saad Ibnsouda Koraichi; Kawtar Fikri-Benbrahim
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Optimization of the Antibacterial Activity of a Three-Component Essential Oil Mixture from Moroccan Thymus satureioides, Lavandula angustifolia, and Origanum majorana Using a Simplex–Centroid Design

Pharmaceuticals
2025-01-07 | Journal article
Contributors: Amine Elbouzidi; Mohamed Taibi; Naoufal El Hachlafi; Mounir Haddou; Mohamed Jeddi; Abdellah Baraich; Saad Bougrine; Ramzi A. Mothana; Mohammed F. Hawwal; Waleed A. Alobaid et al.
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Chemical Composition and Assessment of the Anti-Inflammatory, Antioxidant, Cytotoxic and Skin Enzyme Inhibitory Activities of Citrus sinensis (L.) Osbeck Essential Oil and Its Major Compound Limonene

Pharmaceuticals
2024-12-08 | Journal article
Contributors: Naoufal El Hachlafi; Amine Elbouzidi; Amine Batbat; Mohamed Taibi; Mohamed Jeddi; Mohamed Addi; Hanae Naceiri Mrabti; Kawtar Fikri-Benbrahim
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Natural sources and pharmacological properties of santalenes and santalols

Industrial Crops and Products
2024-08 | Journal article
Part of ISSN: 0926-6690
Contributors: Naoufal El Hachlafi; Nesrine Benkhaira; Ibrahim Mssillou; Jihane Touhtouh; Tarik Aanniz; Imane Chamkhi; Nasreddine El Omari; Asaad Khalid; Ashraf N. Abdalla; Sara Aboulagras et al.
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Naoufal El Hachlafi

Formulation of a Three-Component Essential Oil Mixture from Lavandula dentata, Rosmarinus officinalis, and Myrtus communis for Improved Antioxidant Activity

Pharmaceuticals
2024-08-15 | Journal article
Contributors: Amine Elbouzidi; Mohamed Taibi; Naoufal El Hachlafi; Mounir Haddou; Mohamed Jeddi; Abdellah Baraich; Aya Aouraghe; Reda Bellaouchi; Ramzi A. Mothana; Mohammed F. Hawwal et al.
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Isolation of Arborescin from Artemisia absinthium L. and Study of Its Antioxidant and Antimicrobial Potential by Use of In Vitro and In Silico Approaches

Separations
2024-07-05 | Journal article
Contributors: Asmae Hbika; Amine Elbouzidi; Mohamed Taibi; Safae Ouahabi; El Hassania Loukili; Abdelhamid Bouyanzer; Meryem Idrissi Yahyaoui; Abdeslam Asehraou; Naoufal El Hachlafi; Ahmad Mohammad Salamatullah et al.
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Extraction of Bioactive Compound-Rich Essential Oil from <i>Cistus ladanifer</i> L. by Microwave-Assisted Hydrodistillation: GC-MS Characterization, In Vitro Pharmacological Activities, and Molecular Docking

Separations
2024-06 | Journal article | Author
Contributors: Naoufal El Hachlafi; Fahd Kandsi; Amine Elbouzidi; Fatima Zahra Lafdil; Ghizlane Nouioura; Emad M. Abdallah; Rhizlan Abdnim; Mohamed Bnouham; Samiah Al-Mijalli; Hanae Naceiri mrabti et al.
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Multidisciplinary Digital Publishing Institute
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Phytochemical analysis and acute toxicity of Solanum elaeagnifolium extract in Swiss albino mice

Scientific African
2024-06 | Journal article
Contributors: Mohammed Bouslamti; Ghizlane Nouioura; Fahd Kandsi; Naoufal El Hachlafi; Amal Elrherabi; Badiaa Lyoussi; Ahmed Samir Benjelloun
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Petroselinum crispum L., essential oil as promising source of bioactive compounds, antioxidant, antimicrobial activities: In vitro and in silico predictions

Heliyon
2024-04 | Journal article
Part of ISSN: 2405-8440
Contributors: Ghizlane NOUIOURA ; Mohamed El fadili; Naoufal El Hachlafi; Hatem A. Abuelizz; Ahmed Elfallaki Elidrissi; Mohamed Ferioun; Najoua Soulo; Sara Er-rahmani; Badiaa Lyoussi; Elhoussine Derwich
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Naoufal El Hachlafi

Design of three-component essential oil extract mixture from Cymbopogon flexuosus, Carum carvi, and Acorus calamus with enhanced antioxidant activity

Scientific Reports
2024-04-22 | Journal article
Part of ISSN: 2045-2322
Contributors: Hamza Assaggaf; Mohamed Jeddi; Hanae Naceiri Mrabti; Amine Ez-zoubi; Ahmed Qasem; Ammar Attar; Bey Hing Goh; Sang Loon Tan; Abdelhakim Bouyahya; Khang Wen Goh et al.
Source: Self-asserted source
Naoufal El Hachlafi

Chitosan-grafted Cyclodextrin via Click Chemistry as an Encapsulating Agent to Enhance the Antibacterial Activity of Thymol

Current Bioactive Compounds
2024-01-25 | Journal article
Part of ISSN: 1573-4072
Contributors: Amine Ez-zoubi; Naoufal Elhachlafi; Yassine Ez zoubi; Hicham Zarroual; Wafae Moustaid; Riham Sghyar; Farah Abdellah
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Naoufal El Hachlafi

Phytochemical profile, assessment of antimicrobial and antioxidant properties of essential oils of Artemisia herba-alba Asso., and Artemisia dracunculus L.: Experimental and computational approaches

Journal of Molecular Structure
2023-12 | Journal article
Contributors: Hanae Naceiri Mrabti; Naoufal El Hachlafi; Samiah Hamad Al-Mijalli; Mohamed Jeddi; Amine Elbouzidi; Emad M. Abdallah; Rachid Flouchi; Hamza Assaggaf; Ahmed Qasem; Gokhan Zengin et al.
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Exploration of Novel Antibacterial and Anti-adhesive Formulations from three Chemically Characterized Essential oils: Optimization using experimental design methodology

Scientific African
2023-11 | Journal article
Contributors: Naoufal El Hachlafi; Nesrine Benkhaira; Nouhaila Zouine; Mouhcine Fadil; Mohamed Jeddi; Samir Jeddi; Rachid Flouchi; Saad Ibnsouda Koraichi; Kawtar Fikri-Benbrahim
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GC/MS Profiling, In Vitro Antidiabetic Efficacy of Origanum compactum Benth. Essential Oil and In Silico Molecular Docking of Its Major Bioactive Compounds

Catalysts
2023-11-13 | Journal article
Contributors: Hamza Assaggaf; Naoufal El Hachlafi; Mohamed El fadili; Amine Elbouzidi; Hayat Ouassou; Mohamed Jeddi; Sulaiman Mohammed Alnasser; Ahmed Qasem; Ammar Attar; Ammar AL-Farga et al.
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Application of mixture design for the optimum antibacterial action of chemically-analyzed essential oils and investigation of the antiadhesion ability of their optimal mixtures on 3D printing material

Bioprinting
2023-10 | Journal article
Part of ISSN: 2405-8866
Contributors: Nesrine Benkhaira; Nouhaila Zouine; Mouhcine Fadil; Saad Ibnsouda Koraichi; Naoufal El Hachlafi; Mohamed Jeddi; Mohammed Lachkar; Kawtar Fikri-Benbrahim
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Naoufal El Hachlafi

Integrated analysis of antimicrobial, antioxidant, and phytochemical properties of Cinnamomum verum: A comprehensive In vitro and In silico study

Biochemical Systematics and Ecology
2023-10 | Journal article
Part of ISSN: 0305-1978
Contributors: Samiah Hamad Al-Mijalli; Hanae Naceiri Mrabti; Naoufal El Hachlafi; Taha El Kamili; Amine Elbouzidi; Emad M. Abdallah; Rachid Flouchi ; Hamza Assaggaf; Ahmed Qasem; Gokhan Zengin et al.
Source: Self-asserted source
Naoufal El Hachlafi

Combination of sweet orange, lentisk and lemon eucalyptus essential oils: Optimization of a new complete antimicrobial formulation using a mixture design methodology

Heliyon
2023-09 | Journal article
Contributors: Samiah Hamad Al-Mijalli; Mohamed Jeddi; Naoufal El Hachlafi; Emad M. Abdallah; Hamza Assaggaf; Ahmed Qasem; Bodour S. Rajab; Learn-Han Lee; Abdelhakim Bouyahya; Khang Wen Goh et al.
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Phytochemical analysis and evaluation of antimicrobial, antioxidant, and antidiabetic activities of essential oils from Moroccan medicinal plants: Mentha suaveolens, Lavandula stoechas, and Ammi visnaga

Biomedicine & Pharmacotherapy
2023-08 | Journal article
Contributors: Naoufal El Hachlafi; Nesrine Benkhaira; Samiah Hamad Al-Mijalli; Hanae Naceiri Mrabti; Rhizlan Abdnim; Emad M. Abdallah; Mohamed Jeddi; Mohamed Bnouham; Learn-Han Lee; Chrismawan Ardianto et al.
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Combination of Chemically-Characterized Essential Oils from Eucalyptus polybractea, Ormenis mixta, and Lavandula burnatii: Optimization of a New Complete Antibacterial Formulation Using Simplex-Centroid Mixture Design

Advances in Pharmacological and Pharmaceutical Sciences
2023-08-21 | Journal article
Contributors: Mohamed Jeddi; Naoufal El Hachlafi; Mouhcine Fadil; Nesrine Benkhaira; Samir Jeddi; Zineb Benziane Ouaritini; Kawtar Fikri-Benbrahim; Kuldeep Singh
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Dysphania ambrosioides (L.) Mosyakin and Clemants: bridging traditional knowledge, photochemistry, preclinical investigations, and toxicological validation for health benefits

Naunyn-Schmiedeberg's Archives of Pharmacology
2023-08-08 | Journal article
Part of ISSN: 0028-1298
Part of ISSN: 1432-1912
Contributors: Fahd Kandsi; Fatima Zahra Lafdil; Naoufal El Hachlafi; Mohamed Jeddi; Mohammed Bouslamti; Mohamed El Fadili; Sara Seddoqi; Nadia Gseyra
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Naoufal El Hachlafi

Antioxidant, Volatile Compounds; Antimicrobial, Anti-Inflammatory, and Dermatoprotective Properties of Cedrus atlantica (Endl.) Manetti Ex Carriere Essential Oil: In Vitro and In Silico Investigations

Molecules
2023-08-06 | Journal article
Contributors: Naoufal El Hachlafi; Hanae Naceiri Mrabti; Samiah Hamad Al-Mijalli; Mohamed Jeddi; Emad M. Abdallah; Nesrine Benkhaira; Hanine Hadni; Hamza Assaggaf; Ahmed Qasem; Khang Wen Goh et al.
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Bioactive compounds from Prosopis species as potential oxidative stress and inflammation modulators: an update on mechanisms

Minerva Biotechnology and Biomolecular Research
2023-06 | Journal article
Part of ISSN: 2724-542X
Part of ISSN: 2724-5934
Contributors: Javad SHARIFI-RAD; Naoual EL MENYIY; Alibek YDYRYS; Naoufal EL HACHLAFI; Nasreddine EL OMARI; Afaf A. ALDAHISH; Farukh SHAROPOV; Abdelhakim BOUYAHYA; Jelena ŽIVKOVIĆ; Charles O. ADETUNJI et al.
Source: Self-asserted source
Naoufal El Hachlafi

HPLC-UV-MS/MS Profiling of Phenolics from Euphorbia nicaeensis (All.) Leaf and Stem and Its Antioxidant and Anti-protein Denaturation Activities

progress in microbes & molecular biology
2023-06-11 | Journal article | Conceptualization
Contributors: Naoufal El Hachlafi
Source: Self-asserted source
Naoufal El Hachlafi

Natural sources, biological effects, and pharmacological properties of cynaroside

Biomedicine &amp; Pharmacotherapy
2023-05 | Journal article
Part of ISSN: 0753-3322
Contributors: Abdelhakim Bouyahya; Douae Taha; Taoufiq Benali; Gokhan Zengin; Nasreddine El Omari; Naoufal El Hachlafi; Asaad Khalid; Ashraf N. Abdalla; Chrismawan Ardianto; Ching Siang Tan et al.
Source: Self-asserted source
Naoufal El Hachlafi

Ethnobotanical survey on plants used during the COVID-19 pandemic in Taza (Morocco) and population satisfaction according to the "Rules of Association" approach

Journal of Pharmacy & Pharmacognosy Research
2023-05-01 | Journal article
Contributors: Rachid Flouchi; Mohamed El Far; Nour Elhouda El Atrache; Sabah El Kassmi; Youssra Ezzarouali; Nesrine Benkhaira; Naoufal El Hachlafi; Kawtar Fikri-Benbrahim
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Chemical Profile and Bioactivity of the Essential Oil of Teucrium Takoumitense: An Endemic Lamiaceae from Southeast Morocco

Acta Botanica Hungarica
2023-04-25 | Journal article
Part of ISSN: 0236-6495
Part of ISSN: 1588-2578
Contributors: H. Elbouny; O. El-Guourrami; B. Ouahzizi; N. El Hachlafi; M. Bammou; K. Sellam; C. Alem
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Naoufal El Hachlafi

Moroccan Medicinal Plants Used to Treat Cancer: Ethnomedicinal Study and Insights into Pharmacological Evidence

Evidence-Based Complementary and Alternative Medicine
2022-10-25 | Journal article
Contributors: Naoufal El Hachlafi; Nesrine Benkhaira; Mohamed Ferioun; Fahd Kandsi; Mohamed Jeddi; Abderrahim Chebat; Mohamed Addi; Christophe Hano; Kawtar Fikri-Benbrahim; Rajeev K. Singla
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Dietary Phenolic Compounds as Anticancer Natural Drugs: Recent Update on Molecular Mechanisms and Clinical Trials

Foods
2022-10-23 | Journal article
Contributors: Saad Bakrim; Nasreddine El Omari; Naoufal El Hachlafi; Youssef Bakri; Learn-Han Lee; Abdelhakim Bouyahya
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Pharmacological Properties of Trichostatin A, Focusing on the Anticancer Potential: A Comprehensive Review

Pharmaceuticals
2022-10-08 | Journal article
Contributors: Abdelhakim Bouyahya; Nasreddine El Omari; Mohamed Bakha; Tarik Aanniz; Naoual El Menyiy; Naoufal El Hachlafi; Aicha El Baaboua; Mohamed El-Shazly; Mohammed Merae Alshahrani; Ahmed Abdullah Al Awadh et al.
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Advances in Dietary Phenolic Compounds to Improve Chemosensitivity of Anticancer Drugs

Cancers
2022-09-21 | Journal article
Contributors: Abdelhakim Bouyahya; Nasreddine El Omari; Saad Bakrim; Naoufal El Hachlafi; Abdelaali Balahbib; Polrat Wilairatana; Mohammad S. Mubarak
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Incidence of surgical site infections and prediction of risk factors in a hospital center in Morocco

The Journal of Infection in Developing Countries
2022-07-28 | Journal article
Contributors: Rachid Flouchi; Mohamed El Far; Abdelaziz Hibatallah; Abderrahim Elmniai; Ibtissam Rhbibou; Ibrahim Touzani; Naoufal El Hachlafi; Kawtar Fikri-Benbrahim
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Chemical Compounds of Berry-Derived Polyphenols and Their Effects on Gut Microbiota, Inflammation, and Cancer

Molecules
2022-05-20 | Journal article
Contributors: Abdelhakim Bouyahya; Nasreddine El Omari; Naoufal EL Hachlafi; Meryem El Jemly; Maryam Hakkour; Abdelaali Balahbib; Naoual El Menyiy; Saad Bakrim; Hanae Naceiri Mrabti; Aya Khouchlaa et al.
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Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations

Environmental Science and Pollution Research
2022-04 | Journal article
Part of ISSN: 0944-1344
Part of ISSN: 1614-7499
Contributors: Muhammad Idrees Khan; Abdelhakim Bouyahya; Naoufal E. L. Hachlafi; Naoual El Menyiy; Muhammad Akram; Sabira Sultana; Gokhan Zengin; Lilya Ponomareva; Mohammad Ali Shariati; Oluwafemi Adeleke Ojo et al.
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Naoufal El Hachlafi

Genetic diversity, antimicrobial, nutritional, and phytochemical properties of Chenopodium album: A comprehensive review

Food Research International
2022-04 | Journal article
Part of ISSN: 0963-9969
Contributors: Imane Chamkhi; saoulajan charfi; Naoufal El Hachlafi; Hamza Mechchate; Fatima-Ezzahrae Guaouguaou; Nasreddine El Omari; Saad Bakrim; Abdelaali Balahbib; Gokhan Zengin; Abdelhakim Bouyahya
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Naoufal El Hachlafi

Natural Bioactive Compounds Targeting Histone Deacetylases in Human Cancers: Recent Updates

Molecules
2022-04 | Journal article | Author
Contributors: Abdelhakim Bouyahya; Naoufal El Hachlafi; Tarik Aanniz; Ilhame Bourais; Hamza Mechchate; Taoufiq Benali; Mohammad Ali Shariati; Pavel Burkov; Jose Manuel Lorenzo Rodriguez; Polrat Wilairatana et al.
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Multidisciplinary Digital Publishing Institute
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Vegetables and Their Bioactive Compounds as Anti-Aging Drugs

Molecules
2022-04 | Journal article | Author
Contributors: Hamza Mechchate; Aicha El Allam; Nasreddine El Omari; Naoufal El Hachlafi; Mohammad Ali Shariati; Polrat Wilairatana; Mohammad Mubarak; Abdelhakim Bouyahya
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Multidisciplinary Digital Publishing Institute
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Health beneficial and pharmacological properties of p-cymene

Food and Chemical Toxicology
2021 | Journal article
EID:

2-s2.0-85105811960

Part of ISSN: 18736351 02786915
Contributors: Balahbib, A.; El Omari, N.; Hachlafi, N.E.; Lakhdar, F.; El Menyiy, N.; Salhi, N.; Mrabti, H.N.; Bakrim, S.; Zengin, G.; Bouyahya, A.
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Naoufal El Hachlafi via Scopus - Elsevier

In Vitro and in Vivo Biological Investigations of Camphene and Its Mechanism Insights: A Review

Food Reviews International
2021 | Journal article
EID:

2-s2.0-85108986034

Part of ISSN: 15256103 87559129
Contributors: Hachlafi, N.E.L.; Aanniz, T.; Menyiy, N.E.; Baaboua, A.E.; Omari, N.E.; Balahbib, A.; Shariati, M.A.; Zengin, G.; Fikri-Benbrahim, K.; Bouyahya, A.
Source: Self-asserted source
Naoufal El Hachlafi via Scopus - Elsevier

Sources, health benefits, and biological properties of zeaxanthin

Trends in Food Science &amp; Technology
2021-12 | Journal article | Author
Part of ISSN: 0924-2244
Contributors: Abdelhakim Bouyahya; Nasreddine El Omari; Meryem Hakkur; Naoufal El Hachlafi; saoulajan charfi; Abdelaali Balahbib; Fatima-Ezzahrae Guaouguaou; Maksim Rebezov; Nikolai; Mohammad Ali Shariati et al.
Source: Self-asserted source
Naoufal El Hachlafi
grade
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Health Benefits and Pharmacological Properties of Hinokitiol

Processes
2021-09-18 | Journal article
Contributors: Naoufal El Hachlafi; Fatima Lakhdar; Aya Khouchlaa; Saad Bakrim; Nasreddine El Omari; Abdelaali Balahbib; Mohammad Ali Shariati; Gokhan Zengin; Kawtar Fikri-Benbrahim; Giustino Orlando et al.
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Microbiological Monitoring of the Environment Using the “Association Rules” Approach and Disinfection Procedure Evaluation in a Hospital Center in Morocco

Journal of Environmental and Public Health
2021-07-05 | Journal article
Contributors: Rachid Flouchi; Abderrahim Elmniai; Mohamed El Far; Ibrahim Touzani; Naoufal El Hachlafi; Kawtar Fikri-Benbrahim; Arun S. Kharat
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Crossref

Main Therapeutic Uses of Some Moroccan Hot Springs’ Waters

Evidence-Based Complementary and Alternative Medicine
2021-06-21 | Journal article
Contributors: Kawtar Fikri-Benbrahim; Asmae Houti; Abdelhakim El Ouali Lalami; Rachid Flouchi; Naoufal El Hachlafi; Mariam Houti; Saad Rachiq; Deborah A. Kennedy
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Ethnopharmacology, Phytochemistry, and Pharmacological Properties of Thymus satureioides Coss.

Evidence-Based Complementary and Alternative Medicine
2021-01-27 | Journal article
Contributors: Naoufal El Hachlafi; Abderrahim Chebat; Kawtar Fikri-Benbrahim; Armando Zarrelli
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Ethnopharmacological study of medicinal plants used for chronic diseases treatment in Rabat-SaleKenitra region (Morocco)

Ethnobotany Research and Applications
2020-05-24 | Journal article
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Naoufal El Hachlafi
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Peer review (40 reviews for 20 publications/grants)

Review activity for Acta ecologica Sinica. (3)
Review activity for Antibiotics. (1)
Review activity for Applied sciences. (1)
Review activity for Asian journal of pharmaceutical sciences. (2)
Review activity for Biomedicine & pharmacotherapy. (2)
Review activity for Biomedicines. (1)
Review activity for Cancers. (1)
Review activity for Cells. (1)
Review activity for Food chemistry. (2)
Review activity for Foods. (2)
Review activity for Heliyon. (1)
Review activity for Industrial crops and products. (2)
Review activity for International journal of molecular sciences. (5)
Review activity for Journal of herbal medicine. (1)
Review activity for Micromachines. (1)
Review activity for Microorganisms. (3)
Review activity for Molecules. (6)
Review activity for Pharmaceuticals. (1)
Review activity for Plants. (3)
Review activity for Separations. (1)