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Employment (2)

Institut Pasteur: Paris, FR

2021-04 to present | PI (Immunology and Neuroscience)
Employment
Source: Self-asserted source
Aleksandra Deczkowska

Weizmann Institute of Science: Rehovot, IL

2017-05 to 2021-03 | Post-Doc (Immunology)
Employment
Source: Self-asserted source
Aleksandra Deczkowska

Education and qualifications (3)

Weizmann Institute of Science: Rehovot, IL

2013-11-01 to 2017-05-15 | MSc+PhD (Neurobiology)
Education
Source: Self-asserted source
Aleksandra Deczkowska

Warsaw University of Life Sciences: Warsaw, PL

2007-10 to 2011-02 | BE (Biochenology)
Education
Source: Self-asserted source
Aleksandra Deczkowska

Gent University: Gent, BE

2010-02 to 2010-06 | BE (VIB)
Education
Source: Self-asserted source
Aleksandra Deczkowska

Works (27)

Not so aDAMant after all: Plasticity of phagocytic microglia

Immunity
2024-06 | Journal article
Contributors: Aleksandra Deczkowska
Source: check_circle
Crossref

Microbial and immune factors regulate brain maintenance and aging

Current Opinion in Neurobiology
2022-10 | Journal article
Contributors: Laetitia Travier; Roshani Singh; Daniel Sáenz Fernández; Aleksandra Deczkowska
Source: check_circle
Crossref

The interaction of CD4<sup>+</sup> helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response.

Nature cancer
2022-03-03 | Journal article
Contributors: Merav Cohen; Giladi A; Barboy O; Hamon P; Li B; Zada M; Gurevich-Shapiro A; Cristian Gabriel Beccaria; David E; Barbara Maier et al.
Source: Self-asserted source
Aleksandra Deczkowska

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses.

Journal of visualized experiments : JoVE
2022-02-03 | Journal article
Contributors: Amaia Dominguez Belloso; Schmutz S; sophie novault; Travier L; Deczkowska A
Source: Self-asserted source
Aleksandra Deczkowska

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

Nature Medicine
2021-06 | Journal article
Contributors: Aleksandra Deczkowska; Eyal David; Pierluigi Ramadori; Dominik Pfister; Michal Safran; Baoguo Li; Amir Giladi; Diego Adhemar Jaitin; Oren Barboy; Merav Cohen et al.
Source: check_circle
Crossref

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Nature
2021-04-15 | Journal article
Contributors: Dominik Pfister; Nicolás Gonzalo Núñez; Roser Pinyol; Olivier Govaere; Matthias Pinter; Marta Szydlowska; Revant Gupta; Mengjie Qiu; Aleksandra Deczkowska; Assaf Weiner et al.
Source: check_circle
Crossref

Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies.

Life science alliance
2020-12-04 | Journal article
Contributors: Merav Cohen; Giladi A; Raposo C; Zada M; Li B; Julia Ruckh; Deczkowska A; Boaz Mohar; Ravid Shechter; Lichtenstein RG et al.
Source: Self-asserted source
Aleksandra Deczkowska

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway.

Cell
2020-06-01 | Journal article
Contributors: Deczkowska A; Weiner A; Amit I
Source: Self-asserted source
Aleksandra Deczkowska

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients.

Cell
2020-05-08 | Journal article
Contributors: Bost P; Giladi A; Yang Liu; Bendjelal Y; Xu G; David E; Blecher-Gonen R; Cohen M; Medaglia C; Li H et al.
Source: Self-asserted source
Aleksandra Deczkowska

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Cell
2019-06-27 | Journal article
Contributors: Jaitin DA; Lorenz Adlung; Thaiss CA; Weiner A; Li B; Hélène, C. Descamps; Patrick Lundgren; Camille BLERIOT; Liu Z; Deczkowska A et al.
Source: Self-asserted source
Aleksandra Deczkowska

Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress.

Science advances
2019-05-29 | Journal article | Author
Contributors: Alexander Kertser; Kuti Baruch; Aleksandra Deczkowska; Weiner A; Tommaso Croese; Mor Kenigsbuch; Cooper I; Michael Tsoory; Ben-Hamo S; Ido Amit et al.
Source: Self-asserted source
Aleksandra Deczkowska
grade
Preferred source (of 2)‎

Targeting neuro-immune communication in neurodegeneration: Challenges and opportunities.

The Journal of experimental medicine
2018-10-09 | Journal article
Contributors: Deczkowska A; Michal Schwartz
Source: Self-asserted source
Aleksandra Deczkowska

Microglial immune checkpoint mechanisms

Nature Neuroscience
2018-06 | Journal article
Contributors: Aleksandra Deczkowska; Ido Amit; Michal Schwartz
Source: check_circle
Crossref

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.

Cell
2018-05-01 | Journal article
Contributors: Deczkowska A; Keren-Shaul H; Weiner A; Colonna M; Schwartz M; Amit I
Source: Self-asserted source
Aleksandra Deczkowska

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner

Nature Communications
2017-09-28 | Journal article
Contributors: Aleksandra Deczkowska; Orit Matcovitch-Natan; Afroditi Tsitsou-Kampeli; Sefi Ben-Hamo; Raz Dvir-Szternfeld; Amit Spinrad; Oded Singer; Eyal David; Deborah R. Winter; Lucas K. Smith et al.
Source: check_circle
Crossref

Let's talk about language barriers.

Science (New York, N.Y.)
2017-06-01 | Journal article
Contributors: Deczkowska A
Source: Self-asserted source
Aleksandra Deczkowska

NIX-ing mitochondria: from development to pathology.

The EMBO journal
2017-05-22 | Journal article
Contributors: Deczkowska A; Michal Schwartz
Source: Self-asserted source
Aleksandra Deczkowska

Neurological Disease as a Failure of Brain-Immune Crosstalk: The Multiple Faces of Neuroinflammation.

Trends in immunology
2016-09-06 | Journal article
Contributors: Schwartz M; Deczkowska A
Source: Self-asserted source
Aleksandra Deczkowska

Microglia development follows a stepwise program to regulate brain homeostasis.

Science (New York, N.Y.)
2016-06-23 | Journal article
Contributors: Matcovitch-Natan O; Deborah R. Winter; Giladi A; Stephanie Vargas Aguilar; Amit Spinrad; Sarrazin S; Ben-Yehuda H; David E; Zelada González F; Perrin P et al.
Source: Self-asserted source
Aleksandra Deczkowska

Making Ends Meet: Myeloid Cells Catalyze Blood Vessel Repair in the Brain.

Immunity
2016-05-01 | Journal article
Contributors: Deczkowska A; Schwartz M
Source: Self-asserted source
Aleksandra Deczkowska

Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology.

Trends in immunology
2016-02-11 | Journal article
Contributors: Deczkowska A; Kuti Baruch; Schwartz M
Source: Self-asserted source
Aleksandra Deczkowska

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.

Nature medicine
2016-01-18 | Journal article
Contributors: Kuti Baruch; Deczkowska A; Rosenzweig N; Tsitsou-Kampeli A; Sharif AM; Matcovitch-Natan O; Kertser A; David E; Amit I; Schwartz M
Source: Self-asserted source
Aleksandra Deczkowska

Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.

Nature communications
2015-08-18 | Journal article
Contributors: Kuti Baruch; Rosenzweig N; Kertser A; Deczkowska A; Sharif AM; Amit Spinrad; Tsitsou-Kampeli A; Sarel A; Cahalon L; Schwartz M
Source: Self-asserted source
Aleksandra Deczkowska

TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice.

Journal of autoimmunity
2015-04-22 | Journal article
Contributors: Wen J; Jessica Doerner; Weidenheim K; Xia Y; Stock A; Michaelson JS; Kuti Baruch; Deczkowska A; Maria Gulinello; Schwartz M et al.
Source: Self-asserted source
Aleksandra Deczkowska

Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

Science (New York, N.Y.)
2014-08-21 | Journal article
Contributors: Kuti Baruch; Deczkowska A; David E; Joseph M. Castellano; Miller O; Kertser A; Berkutzki T; Zohar Barnett-Itzhaki; Bezalel D; Tony Wyss-Coray et al.
Source: Self-asserted source
Aleksandra Deczkowska

CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.

Frontiers in immunology
2013-11-19 | Journal article
Contributors: Eric Shifrut; Kuti Baruch; Gal H; Ndifon W; Deczkowska A; Schwartz M; Friedman N
Source: Self-asserted source
Aleksandra Deczkowska

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging.

Proceedings of the National Academy of Sciences of the United States of America
2013-01-18 | Journal article
Contributors: Kuti Baruch; Ron-Harel N; Gal H; Deczkowska A; Eric Shifrut; Ndifon W; Mirlas-Neisberg N; Cardon M; Vaknin I; Cahalon L et al.
Source: Self-asserted source
Aleksandra Deczkowska

Peer review (10 reviews for 4 publications/grants)

Review activity for Cell reports. (2)
Review activity for Immunity. (5)
Review activity for JoVE. (2)
Review activity for Science immunology. (1)