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Loop profile: 714056

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Employment (4)

Queen Mary University of London: London, London, GB

2020-07 to present | Lecturer in Pharmacology (Barts and The London School of Medicine and Dentistry )
Employment
Source: Self-asserted source
Paul C Armstrong

Queen Mary University of London: London, London, GB

2017-07 to 2020-07 | Postdoctoral Research Associate (Blizard Institute, Barts and The London School of Medicine and Dentistry )
Employment
Source: Self-asserted source
Paul C Armstrong

Queen Mary University of London: London, London, GB

2012-12-01 to 2017-06-30 | Postdoctoral Research Associate (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry )
Employment
Source: Self-asserted source
Paul C Armstrong

Baker IDI Heart and Diabetes Institute: Melbourne, Victoria, AU

2009 to 2012
Employment
Source: Self-asserted source
Paul C Armstrong

Education and qualifications (1)

Queen Mary University of London: London, London, GB

2005-10 to 2009-07 | PhD
Education
Source: Self-asserted source
Paul C Armstrong

Professional activities (2)

International Society on Thrombosis and Haemostasis : NC, NC, US

2020-11 to present | Member (Publications Committee)
Invited position
Source: Self-asserted source
Paul C Armstrong

International Society on Thrombosis and Haemostasis: NC, NC, US

2020-08 to present | Member (Early Career Committee)
Invited position
Source: Self-asserted source
Paul C Armstrong

Funding (2)

Exploring the phenotypic and functional consequences of platelet-monocyte binding within whole blood to elucidate its contribution to inflammation and immunothrombosis

2021-10 to 2022-10 | Grant
Barts Charity (London, GB)
Source: Self-asserted source
Paul C Armstrong

The association between platelet age and platelet function; relevance to thrombotic risk

Grant
British Heart Foundation (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.9401059
GRANT_NUMBER:

BHF-RG/19/8/34500
Source: Self-asserted source
Paul C Armstrong via DimensionsWizard

Works (50 of 74)

Items per page:
Page 1 of 2

Platelet mitochondrial transfer via extracellular vesicles modulates neutrophil phenotype and function

2025-01-29 | Preprint
DOI: 10.1101/2025.01.29.635414
Contributors: Harriet E. Allan; Nicola Dark; Paul Vulliamy; Marilena Crescente; Paul C. Armstrong; Plinio Ferreira; Timothy D. Warner
Source: check_circle
Crossref

Thrombocytopenia in murine schistosomiasis is associated with platelet uptake by liver macrophages that have a distinct activation phenotype

2024-11-03 | Preprint
DOI: 10.1101/2024.10.29.620826
Contributors: Joanna H Greenman; Shinjini Chakraborty; Lucie Moss; Paul C Armstrong; Paul M Kaye; Ian S Hitchcock; James P Hewitson
Source: check_circle
Crossref

Multiparameter phenotyping of platelets and characterization of the effects of agonists using machine learning

Research and Practice in Thrombosis and Haemostasis
2024-07 | Journal article
DOI: 10.1016/j.rpth.2024.102523
Contributors: Ami Vadgama; James Boot; Nicola Dark; Harriet E. Allan; Charles A. Mein; Paul C. Armstrong; Timothy D. Warner
Source: check_circle
Crossref

Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma

Arteriosclerosis, Thrombosis, and Vascular Biology
2024-03 | Journal article
DOI: 10.1161/ATVBAHA.123.318801
Contributors: Paul Vulliamy; Paul C. Armstrong
Source: check_circle
Crossref

What can we learn from senescent platelets, their transcriptomes and proteomes?

Platelets
2023-12-31 | Journal article
DOI: 10.1080/09537104.2023.2200838
Contributors: Harriet E. Allan; Ami Vadgama; Paul C. Armstrong; Timothy D. Warner
Source: check_circle
Crossref

Multi-parameter phenotyping of platelets and characterisation of the effects of agonists using machine learning

2023-12-10 | Preprint
DOI: 10.1101/2023.12.08.570628
Contributors: Ami Vadgama; James Boot; Harriet E. Allan; Charles A. Mein; Paul C. Armstrong; Timothy D. Warner
Source: check_circle
Crossref

Widening the Prostacyclin Paradigm: Tissue Fibroblasts Are a Critical Site of Production and Antithrombotic Protection

Arteriosclerosis, Thrombosis, and Vascular Biology
2023-10-12 | Journal article
DOI: 10.1161/ATVBAHA.123.318923
Contributors: Maria Vinokurova; Maria Elisa Lopes-Pires; Neringa Cypaite; Fisnik Shala; Paul C. Armstrong; Blerina Ahmetaj-Shala; Youssef Elghazouli; Rolf Nüsing; Bin Liu; Yingbi Zhou et al.
Source: check_circle
Crossref

Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

Blood Advances
2022-12-13 | Journal article
DOI: 10.1182/bloodadvances.2022007099
Contributors: Paul C. Armstrong; Harriet E. Allan; Nicholas S. Kirkby; Clemens Gutmann; Abhishek Joshi; Marilena Crescente; Jane A. Mitchell; Manuel Mayr; Timothy D. Warner
Source: check_circle
Crossref

Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity

Arteriosclerosis, Thrombosis, and Vascular Biology
2022-01 | Journal article
DOI: 10.1161/ATVBAHA.121.317113
Contributors: Abhishek Joshi; Lukas E. Schmidt; Sean A. Burnap; Ruifang Lu; Melissa V. Chan; Paul C. Armstrong; Ferheen Baig; Clemens Gutmann; Peter Willeit; Peter Santer et al.
Source: check_circle
Crossref

Tissue fibroblasts are a critical source of prostacyclin and anti-thrombotic protection

2022-01-12 | Preprint
DOI: 10.1101/2022.01.11.475814
Contributors: Jane A. Mitchell; Maria Vinokurova; Maria Elisa Lopes-Pires; Fisnik Shala; Paul C. Armstrong; Blerina Ahmetaj-Shala; Youssef Elghazouli; Bin Liu; Yingbi Zhou; Chuan-ming Hao et al.
Source: check_circle
Crossref

Platelet inhibition by P2Y12 antagonists is potentiated by adenosine signalling activators

British Journal of Pharmacology
2021-12 | Journal article
DOI: 10.1111/bph.15659
Contributors: Chih‐Chin Shih; Melissa V. Chan; Nicholas S. Kirkby; Ivana Vojnovic; Jane A. Mitchell; Paul C. Armstrong; Timothy D. Warner
Source: check_circle
Crossref

Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

2021-12-20 | Preprint
DOI: 10.1101/2021.12.17.473131
Contributors: Paul C Armstrong; Harriet E Allan; Nicholas S Kirkby; Abhishek Joshi; Clemens Gutmann; Marilena Crescente; Jane A Mitchell; Manuel Mayr; Timothy D Warner
Source: check_circle
Crossref

Impact of the COVID‐19 pandemic on education and clinical training

Journal of Thrombosis and Haemostasis
2021-09 | Journal article
DOI: 10.1111/jth.15470
Contributors: Muntadhar Al Moosawi; Aaron Iding; Paul Armstrong; Thita Chiasakul; Robert Campbell; Caterina Casari; Claire McLintock; Muntadhar Al Moosawi; Paul Armstrong; Rose Brazilek et al.
Source: check_circle
Crossref

Combination of cyclic nucleotide modulators with P2Y12 receptor antagonists as anti‐platelet therapy

Journal of Thrombosis and Haemostasis
2020-07 | Journal article
DOI: 10.1111/jth.14826
Contributors: Paul C. Armstrong; Plinio M. Ferreira; Melissa V. Chan; Martina H. Lundberg Slingsby; Marilena Crescente; Chih‐Chin Shih; Nicholas S. Kirkby; Adrian J. Hobbs; Timothy D. Warner
Source: check_circle
Crossref

Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients

Blood Advances
2020-06-23 | Journal article
DOI: 10.1182/bloodadvances.2020001776
Contributors: Paul Vulliamy; Samantha J. Montague; Scarlett Gillespie; Melissa V. Chan; Lucy A. Coupland; Robert K. Andrews; Timothy D. Warner; Elizabeth E. Gardiner; Karim Brohi; Paul C. Armstrong
Source: check_circle
Crossref

Platelet Reactivity in Individuals Over 65 Years Old Is not Modulated by Age

Circulation Research
2020-04-27 | Journal article
DOI: 10.1161/CIRCRESAHA.119.316324
Contributors: Melissa V Chan; Ming-Huei Chen; Temo Barwari; Jennifer E Huffman; Paul Charles Armstrong; Shih-Jen Hwang; Peter Santer; Brigitte Wierer; Manuel Mayr; Stefan Kiechl et al.
Source: check_circle
Crossref

Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage.

Proceedings of the National Academy of Sciences of the United States of America
2019-08-12 | Journal article
DOI: 10.1073/pnas.1904978116
PMID: 31405966
Source: Self-asserted source
Paul C Armstrong

Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)

British Journal of Pharmacology
2019-04 | Journal article
DOI: 10.1111/bph.14196
Contributors: Marilena Crescente; Laura Menke; Melissa V Chan; Paul C Armstrong; Timothy D Warner
Source: check_circle
Crossref

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2

Journal of Clinical Investigation
2019-03-25 | Journal article
DOI: 10.1172/JCI121985
Contributors: Serena Lucotti; Camilla Cerutti; Magali Soyer; Ana M. Gil-Bernabé; Ana L. Gomes; Philip D. Allen; Sean Smart; Bostjan Markelc; Karla Watson; Paul C. Armstrong et al.
Source: check_circle
Crossref

Inhibition of profibrotic microRNA-21 affects platelets and their releasate

JCI Insight
2018-11-02 | Journal article
DOI: 10.1172/jci.insight.123335
Contributors: Temo Barwari; Seda Eminaga; Ursula Mayr; Ruifang Lu; Paul C. Armstrong; Melissa V. Chan; Mahnaz Sahraei; Marta Fernández-Fuertes; Thomas Moreau; Javier Barallobre-Barreiro et al.
Source: check_circle
Crossref

Platelet responses to pharmacological and physiological interventions in middle‐aged men with different habitual physical activity levels

Acta Physiologica
2018-05 | Journal article
DOI: 10.1111/apha.13028
Contributors: M. H. Lundberg Slingsby; L. Gliemann; M. Thrane; N. Rytter; J. Egelund; M. V. Chan; P. C. Armstrong; T. D. Warner; Y. Hellsten
Source: check_circle
Crossref

Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet TherapiesHighlights

Arteriosclerosis, Thrombosis, and Vascular Biology
2017-03-09 | Journal article
DOI: 10.1161/atvbaha.116.308763
Contributors: Paul C. Armstrong; Thomas Hoefer; Rebecca B. Knowles; Arthur T. Tucker; Melissa A. Hayman; Plinio M. Ferreira; Melissa V. Chan; Timothy D. Warner
Source: Self-asserted source
Paul C Armstrong via Crossref Metadata Search

Association of MicroRNAs and YRNAs With Platelet Function.

2016-02 | Journal article
DOI: 10.1161/CIRCRESAHA.114.305663
PMID: 26646931
Contributors: Kaudewitz D; Skroblin P; Bender LH; Barwari T; Willeit P; Pechlaner R; Sunderland NP; Willeit K; Morton AC; Armstrong PC et al.
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

The importance of endothelium-derived mediators to the efficacy of dual anti-platelet therapy.

2016-01 | Journal article
PMID: 26822235
Contributors: Warner TD; Armstrong PC; Chan MV; Knowles RB
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

213 Synergy between Endothelial Mediators and P2Y12 Receptor Blockade as a Potential Determinant in Tailoring Anti-Platelet Therapy

Heart
2015 | Journal article
Source: Self-asserted source
Paul C Armstrong

Characterising cell-type interactions following platelet activation in a novel low volume whole blood assay

JOURNAL OF THROMBOSIS AND HAEMOSTASIS
2015 | Conference paper
Source: Self-asserted source
Paul C Armstrong

Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs

Circulation
2015 | Journal article
Source: Self-asserted source
Paul C Armstrong

Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction

Blood
2015 | Journal article
DOI: 10.1182/blood-2015-01-621656
PMID: 26215112
Source: Self-asserted source
Paul C Armstrong
grade
Preferred source (of 2)‎

Prostaglandin E1 potentiates the effects of P2Y12 blockade on ADP-mediated platelet aggregation in vitro: Insights using short thromboelastography

Platelets
2015 | Journal article
Source: Self-asserted source
Paul C Armstrong

Prostaglandin E1 potentiates the effects of P2Y12 blockade on ADP-mediated platelet aggregation in vitro: Insights using short thromboelastography.

2015 | Journal article
DOI: 10.3109/09537104.2014.1001832
PMID: 25734957
Contributors: Khanna V; Armstrong PC; Warner TD; Curzen N
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach

BMJ open
2015 | Journal article
Source: Self-asserted source
Paul C Armstrong

Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach.

2015 | Journal article
DOI: 10.1136/bmjopen-2014-005750
PMID: 25631307
PMC: PMC4316420
Contributors: Ross CL; Galloway-Phillipps N; Armstrong PC; Mitchell JA; Warner TD; Brearley C; Ito M; Tunstall T; Elkin S; Kon OM et al.
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

THE ANTI-PLATELET EFFECTIVENESS OF P2Y12 RECEPTOR BLOCKADE IS STRONGLY INFLUENCED BY THE ENDOTHELIUM-DERIVED MEDIATORS NITRIC OXIDE AND PROSTACYCLIN

HEART
2015 | Conference paper
Source: Self-asserted source
Paul C Armstrong

The effectiveness of P2Y12 receptor blockade is strongly determined by the presence of endothelial Mediators prostacyclin and nitric oxide

JOURNAL OF THROMBOSIS AND HAEMOSTASIS
2015 | Conference paper
Source: Self-asserted source
Paul C Armstrong

P2Y12 receptor blockade synergises strongly with nitric oxide and prostacyclin to inhibit platelet activation.

2015-11 | Journal article
PMID: 26561399
Contributors: Chan MV; Knowles RB; Lundberg MH; Tucker AT; Mohamed NA; Kirkby NS; Armstrong PC; Mitchell JA; Warner TD
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy.

2015-10 | Journal article
DOI: 10.1161/ATVBAHA.115.306219
PMID: 26272940
Contributors: Hoefer T; Armstrong PC; Finsterbusch M; Chan MV; Kirkby NS; Warner TD
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

Reply to letter regarding article, "evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs".

2015-10 | Journal article
DOI: 10.1161/CIRCULATIONAHA.115.017260
PMID: 26503755
Contributors: Ahmetaj-Shala B; Kirkby NS; Knowles R; Al'Yamani M; Mazi S; Wang Z; Tucker AT; Mackenzie LS; Armstrong PC; Nüsing RM et al.
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs.

2015-02 | Journal article
DOI: 10.1161/CIRCULATIONAHA.114.011591
PMID: 25492024
Contributors: Ahmetaj-Shala B; Kirkby NS; Knowles R; Al'Yamani M; Mazi S; Wang Z; Tucker AT; Mackenzie L; Armstrong PC; Nüsing RM et al.
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

The Effectiveness of P2Y12 Receptor Antagonist Therapy is Strongly Determined by Endothelial Mediators of Platelet Function

Circulation
2014 | Journal article
Source: Self-asserted source
Paul C Armstrong

GPIIb/IIIa inhibitors: From bench to bedside and back to bench again

Thrombosis and Haemostasis
2012 | Journal article
Source: Self-asserted source
Paul C Armstrong

Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis

2012 | Journal article
Source: Self-asserted source
Paul C Armstrong

Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis Validation of a Unique Noninvasive Method for Rapid and Sensitive Detection of Thrombi and Monitoring of Success or Failure of Thrombolysis in Mice

Circulation
2012 | Journal article
Source: Self-asserted source
Paul C Armstrong

Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose

Journal of Thrombosis and Haemostasis
2012 | Journal article
Source: Self-asserted source
Paul C Armstrong

Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and monitoring of success or failure of thrombolysis in mice.

2012-06 | Journal article
DOI: 10.1161/CIRCULATIONAHA.111.030312
PMID: 22647975
Contributors: Wang X; Hagemeyer CE; Hohmann JD; Leitner E; Armstrong PC; Jia F; Olschewski M; Needles A; Peter K; Ahrens I
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

GPIIb/IIIa inhibitors: from bench to bedside and back to bench again.

2012-05 | Journal article
DOI: 10.1160/TH11-10-0727
PMID: 22370973
Contributors: Armstrong PC; Peter K
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia

Arteriosclerosis, thrombosis, and vascular biology
2011 | Journal article
Source: Self-asserted source
Paul C Armstrong

GPVI and GPIb$α$ mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

PloS one
2011 | Journal article
Source: Self-asserted source
Paul C Armstrong

GPVI and GPIBI-alpha mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

PLoS ONE [P]
2011 | Journal article
Source: Self-asserted source
Paul C Armstrong

GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors.

2011 | Journal article
DOI: 10.1371/journal.pone.0019190
PMID: 21552524
PMC: PMC3084272
Contributors: Hu H; Armstrong PC; Khalil E; Chen YC; Straub A; Li M; Soosairajah J; Hagemeyer CE; Bassler N; Huang D et al.
Source: Self-asserted source
Paul C Armstrong via Europe PubMed Central

In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

Journal of Thrombosis and Haemostasis
2011 | Journal article
Source: Self-asserted source
Paul C Armstrong
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Peer review (3 reviews for 3 publications/grants)

Review activity for Cardiovascular research. (1)
Review activity for Nature cardiovascular research. (1)
Review activity for Thrombosis research. (1)
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