Personal information

United States

Biography

At NIBR since 2008, Denise Yates has leads effort focused on developing the strategy and implementation of clinical imaging in the early phase proof of concept human trials for the Translational Medicine Cardiovascular, Respiratory and New Indications groups. In her role, she has lead the collaborative efforts with expert imaging centers in Radiology and Cardiology departments of high profile academic centers to implement state of the art technologies for robust Phase II clinical trials. In a role as Therapeutic Area head for Biomarker Development Cardiovascular and Metabolism she supports the biomarker development portfolio for cardiovascular trials that includes genomic, proteomic, metabolic and novel technology approaches. Prior to joining Novartis, Dr. Yates was a faculty member of Department of Radiology, Massachusetts General Hospital at the Martinos Center for Biomedical Imaging and Assistant Professor, Harvard Medical School since 1999. She has served as scientific reviewer for the American Heart Association, journal reviewer for Circulation, CV imaging and has authored over 60 publications and conference proceedings.

Activities

Employment (2)

Novartis Institutes for BioMedical Research Inc: Cambridge, MA, US

2008-11-19 to present | CVM Therapeutic Area Head (Biomarker Development)
Employment
Source: Self-asserted source
Denise Yates

Massachusetts General Hospital: Boston, Massachusetts, US

1997-09 to 2008-10 | Assistant Professor (Radiology)
Employment
Source: Self-asserted source
Denise Yates

Education and qualifications (2)

University of North Carolina System: Chapel Hill, NC, US

1987-09 to 1992-12 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Denise Yates

American University: Washington, DC, US

1982-09 to 1986-06 | Bachelor of Science (Mathematics)
Education
Source: Self-asserted source
Denise Yates

Works (21)

Data from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Data from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

Cancer Prevention Research
2024-09-04 | Journal article
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Figure S1 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Figure S1 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Figure S2 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Figure S2 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S1 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S1 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S2 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S2 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S3 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S3 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S4 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Supplementary Table S4 from Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial

2024-09-04 | Preprint
Contributors: Janghee Woo; Tingting Zhai; Fang Yang; Huilei Xu; Margaret L. Healey; Denise P. Yates; Michael T. Beste; David P. Steensma
Source: check_circle
Crossref

Effects of IL-1β inhibition on anemia and clonal hematopoiesis in the randomized CANTOS trial

Blood Advances
2023-12-26 | Journal article
Contributors: Janghee Woo; Darlene Lu; Andrew Lewandowski; Huilei Xu; Pablo Serrano; Margaret Healey; Denise P. Yates; Michael T. Beste; Peter Libby; Paul M. Ridker et al.
Source: check_circle
Crossref

Aptamer Proteomics for Biomarker Discovery in Heart Failure With Reduced Ejection Fraction

Circulation
2022-11 | Journal article
Contributors: Luqing Zhang; Jonathan W. Cunningham; Brian L. Claggett; Jaison Jacob; Michael M. Mendelson; Pablo Serrano-Fernandez; Sergio Kaiser; Denise P. Yates; Margaret Healey; Chien-Wei Chen et al.
Source: check_circle
Crossref

Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial

Circulation: Genomic and Precision Medicine
2021-12 | Journal article
Contributors: Huilei Xu; Claudia Hon; Sergio Kaiser; Pablo Serrano-Fernandez; Nicole Hartmann; Denise P. Yates; Margaret Healey; Arkady I. Gusev; Jason M. Laramie; Scott Kennedy et al.
Source: check_circle
Crossref

Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial

Cardiovascular Research
2021-01-01 | Journal article
Contributors: David Corcoran; Aleksandra Radjenovic; Ify R Mordi; Sheraz A Nazir; Simon J Wilson; Markus Hinder; Denise P Yates; Surendra Machineni; Jose Alcantara; Margaret F Prescott et al.
Source: check_circle
Crossref

<p>Efficacy and Safety of the CFTR Potentiator Icenticaftor (QBW251) in COPD: Results from a Phase 2 Randomized Trial</p>

International Journal of Chronic Obstructive Pulmonary Disease
2020-10 | Journal article
Contributors: Steven M Rowe; Ieuan Jones; Mark T Dransfield; Nazmul Haque; Stephen Gleason; Katy A Hayes; Kenneth Kulmatycki; Denise P Yates; Henry Danahay; Martin Gosling et al.
Source: check_circle
Crossref

Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement

Radiology: Cardiothoracic Imaging
2020-04-01 | Journal article
Contributors: Maja Hrabak-Paar; Achim Kircher; Saeed Al Sayari; Sebastien Kopp; Francesco Santini; Roland E. Schmieder; Nadjia Kachenoura; Denise Yates; Thomas Langenickel; Jens Bremerich et al.
Source: check_circle
Crossref