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Other IDs

Loop profile: 889048

Countries

Netherlands, United States

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Employment (2)

University of California, San Francisco: San Francisco, US

2023-10-01 to present | Postdoc (Pharmaceutical chemistry)
Employment
Source: Self-asserted source
Niek van Hilten

Leiden University: Leiden, NL

2018-10-01 to 2023-09-14 | PhD Candidate (Leiden Institute of Chemistry)
Employment
Source: Self-asserted source
Niek van Hilten

Education and qualifications (4)

Leiden University: Leiden, NL

2018-10-01 to 2023-09-14 | PhD (Leiden Institute of Chemistry)
Education
Source: Self-asserted source
Niek van Hilten

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

2015-09-01 to 2017-12-31 | MSc (Molecular Life Sciences)
Education
Source: Self-asserted source
Niek van Hilten

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

2013-09-01 to 2015-08-31 | BSc (Molecular Life Sciences)
Education
Source: Self-asserted source
Niek van Hilten

Radboud Universiteit Nijmegen: Nijmegen, Gelderland, NL

2010-09-01 to 2013-08-31 | BSc (Natural Sciences)
Education
Source: Self-asserted source
Niek van Hilten

Works (14)

Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation

Cell Reports
2024-03 | Journal article
DOI: 10.1016/j.celrep.2024.113866
Part of ISSN: 2211-1247
Contributors: Harry Warner; Giulia Franciosa; Guus van der Borg; Britt Coenen; Felix Faas; Claire Koenig; Rinse de Boer; René Classens; Sjors Maassen; Maksim V. Baranov et al.
Source: Self-asserted source
Niek van Hilten

When Data Are Lacking: Physics-Based Inverse Design of Biopolymers Interacting with Complex, Fluid Phases

Journal of Chemical Theory and Computation
2024-02-27 | Journal article | Author
DOI: 10.1021/acs.jctc.3c00874
Part of ISSN: 1549-9618
Part of ISSN: 1549-9626
Contributors: Jeroen Methorst; Niek van Hilten; Art Hoti; Kai Steffen Stroh; Herre Jelger Risselada
Source: Self-asserted source
Niek van Hilten

PMIpred: a physics-informed web server for quantitative protein–membrane interaction prediction

Bioinformatics
2024-02-01 | Journal article | Author
DOI: 10.1093/bioinformatics/btae069
Part of ISSN: 1367-4803
Part of ISSN: 1367-4811
Contributors: Niek van Hilten; Nino Verwei; Jeroen Methorst; Carsten Nase; Andrius Bernatavicius; Herre Jelger Risselada
Source: Self-asserted source
Niek van Hilten

Phase‐Separated Lipid‐Based Nanoparticles: Selective Behavior At The Nano‐Bio Interface

Advanced Materials
2023-11-21 | Journal article
DOI: 10.1002/adma.202310872
Part of ISSN: 0935-9648
Part of ISSN: 1521-4095
Contributors: Panagiota Papadopoulou; Rianne van der Pol; Niek van Hilten; Winant L. van Os; Roy Pattipeiluhu; Gabriela Arias‐Alpizar; Renzo A. Knol; Willem Noteborn; Mohammad‐Amin Moradi; Maria J. Ferraz et al.
Source: Self-asserted source
Niek van Hilten
grade
Preferred source (of 2)‎

Inverse design of curvature-sensing antiviral peptides

2023-09-14 | Dissertation or Thesis
OTHER-ID:

8cdfc4f9-b592-4ddd-86dc-1eacc1eefb28
Contributors: Hilten; N. van
Source: check_circle
Leiden University

Physics-based generative model of curvature sensing peptides; distinguishing sensors from binders

Science Advances
2023-03-15 | Journal article | Author
DOI: 10.1126/sciadv.ade8839
Part of ISSN: 2375-2548
Contributors: Niek van Hilten; Jeroen Methorst; Nino Verwei; Herre Jelger Risselada
Source: Self-asserted source
Niek van Hilten

Azobenzene-based amino acids for the photocontrol of coiled-coil peptides

Bioconjugate Chemistry
2023-01-27 | Journal article
DOI: 10.1021/acs.bioconjchem.2c00534
OTHER-ID:

21a56469-c0f1-45d1-b5bf-fa86ae24e8ec
Contributors: Crone; N.S. A.; Hilten; N. van; Ham; A. van der; Risselada. H.J.; Kros; A.; Boyle; A.L.
Source: check_circle
Leiden University

Efficient Quantification of Lipid Packing Defect Sensing by Amphipathic Peptides: Comparing Martini 2 and 3 with CHARMM36

Journal of Chemical Theory and Computation
2022-06-16 | Journal article
DOI: 10.1021/acs.jctc.2c00222
Part of ISSN: 1549-9618
Part of ISSN: 1549-9626
Source: Self-asserted source
Niek van Hilten
grade
Preferred source (of 2)‎

Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor.

Journal of medicinal chemistry
2020-09-25 | Journal article
DOI: 10.1021/acs.jmedchem.0c00964
PMID: 32977721
Source: Self-asserted source
Niek van Hilten

Membrane Thinning Induces Sorting of Lipids and the Amphipathic Lipid Packing Sensor (ALPS) Protein Motif

Frontiers in Physiology
2020-04-16 | Journal article
DOI: 10.3389/fphys.2020.00250
Part of ISSN: 1664-042X
Source: Self-asserted source
Niek van Hilten
grade
Preferred source (of 2)‎

Virtual Compound Libraries in Computer-Assisted Drug Discovery.

Journal of chemical information and modeling
2019-01 | Journal article
DOI: 10.1021/acs.jcim.8b00737
PMID: 30624918
Contributors: van Hilten N; Chevillard F; Kolb P
Source: Self-asserted source
Niek van Hilten via Europe PubMed Central

Potent metabolic sialylation inhibitors based on C-5 modified fluorinated sialic acids

Journal of Medicinal Chemistry
2018 | Journal article
DOI: 10.1021/acs.jmedchem.8b01757
Part of ISSN: 0022-2623
Contributors: Torben Heise; Johan Pijnenborg; Christian Büll; Niek van Hilten; Esther Kers-Rebel; Natasja Balneger; Hidde Elferink; Gosse J Adema; Thomas J. Boltje
Source: Self-asserted source
Niek van Hilten via Crossref Metadata Search

Binding-Site Compatible Fragment Growing Applied to the Design of β2-Adrenergic Receptor Ligands.

Journal of medicinal chemistry
2018-01 | Journal article
PMID: 29364664
Contributors: Chevillard F; Rimmer H; Betti C; Pardon E; Ballet S; van Hilten N; Steyaert J; Diederich WE; Kolb P
Source: Self-asserted source
Niek van Hilten via Europe PubMed Central

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.

Angewandte Chemie (International ed. in English)
2017-03 | Journal article
DOI: 10.1002/anie.201612193
PMID: 28194834
Source: Self-asserted source
Niek van Hilten via Europe PubMed Central
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