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Biography
Cancer Research: Dr. Feng is Director of the Laboratory of Zebrafish Genetics and Cancer Therapeutics. Dr. Feng’s research interests focus on identifying novel genes and pathways that are essential for MYC-related tumor transformation and progression, particularly for T-Lymphoblastic Lymphoma/Leukemia and Neuroblastoma. The research strategy of Dr. Feng’s research is to combine the analysis of human cancer genomic databases with the genetic and imaging capacities of the zebrafish system.
Current research areas in Dr. Feng’s laboratory include:
1) To determine the molecular mechanisms underlying tumor cell intravasation and tumor progression.
2) To test the identified genes’ therapeutic potential in treating MYC-related cancers and to characterize their molecular relevance to MYC.
3) To identify additional genes and pathways that, when mutated, delay the initiation and progression of MYC-related cancers.
The long-term goal of Dr. Feng’s research is to discover novel molecular therapies to target critical components of MYC-driven oncogenic pathways, thus providing treatment alternatives that are more specific and less toxic.
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Works (50 of 53)
WOS:000447600004395
WOS:000389969800112
WOS:000331385002396
WOS:000209701505163
10.1038/leu.2012.116
22538478
10.1016/j.ccr.2012.02.010
22439933
WOS:000209701301305
10.1084/jem.20101691
21727187
10.1016/j.ccr.2010.09.009
20951945
10.1016/j.ydbio.2010.07.020
20659444
WOS:000272725804641
10.1002/gcc.20623
18973135
10.1111/j.1365-2141.2007.06625.x
17593023
10.1016/j.cub.2007.04.055
17509881
WOS:000242440001664
10.1073/pnas.0408708102
15827121
10.4161/cc.2.5.527
12963835