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Employment (1)

The University of Texas at Austin: Austin, TX, US

2016-01-01 to present | Graduate Research Assistant (Molecular Biosciences)
Employment
Source: Self-asserted source
Tyler L. Dangerfield

Education and qualifications (2)

The University of Texas at Austin: Austin, TX, US

2016-01-01 to present | PhD Biochemistry (Molecular Biosciences)
Education
Source: Self-asserted source
Tyler L. Dangerfield

University of Texas at Austin: Austin, TX, US

2011-08-01 to 2015-12-15 | B.S. Biochemistry (Biochemistry)
Education
Source: Self-asserted source
Tyler L. Dangerfield

Works (19)

DNA targeting by compact Cas9d and its resurrected ancestor

Nature Communications
2025-01-07 | Journal article
DOI: 10.1038/s41467-024-55573-4
Contributors: Rodrigo Fregoso Ocampo; Jack P. K. Bravo; Tyler L. Dangerfield; Isabel Nocedal; Samatar A. Jirde; Lisa M. Alexander; Nicole C. Thomas; Anjali Das; Sarah Nielson; Kenneth A. Johnson et al.
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Crossref

Single-turnover kinetic analysis of non-LTR retrotransposition defines the mechanism and rate constants governing each step

2024-09-04 | Preprint
DOI: 10.21203/rs.3.rs-4992860/v1
Contributors: Kenneth Johnson; Tyler Dangerfield; Jun Zhou; Thomas Eickbush
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Crossref

Single-turnover kinetic analysis of non-LTR retrotransposition defines the mechanism and rate constants governing each step

2024-08-29 | Preprint
DOI: 10.1101/2024.08.28.610141
Contributors: Tyler L. Dangerfield; Jun Zhou; Thomas Eickbush; Kenneth A. Johnson
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Crossref

RNA targeting and cleavage by the type III-Dv CRISPR effector complex

Nature Communications
2024-04-18 | Journal article
DOI: 10.1038/s41467-024-47506-y
Contributors: Evan A. Schwartz; Jack P. K. Bravo; Mohd Ahsan; Luis A. Macias; Caitlyn L. McCafferty; Tyler L. Dangerfield; Jada N. Walker; Jennifer S. Brodbelt; Giulia Palermo; Peter C. Fineran et al.
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Crossref

DNA targeting by compact Cas9d and its resurrected ancestor

2024-04-08 | Preprint
DOI: 10.1101/2024.04.08.588528
Contributors: Rodrigo Fregoso Ocampo; Jack P. K. Bravo; Tyler Dangerfield; Isabel Nocedal; Samatar Jirde; Lisa M. Alexander; Anjali Das; Sarah Nielsen; Kenneth A. Johnson; Christopher T. Brown et al.
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Crossref

Unraveling the mechanisms of PAMless DNA interrogation by SpRY Cas9

2023-06-22 | Preprint
DOI: 10.1101/2023.06.22.546082
Contributors: Grace N. Hibshman; Jack P. K. Bravo; Hongshan Zhang; Tyler L. Dangerfield; Ilya J. Finkelstein; Kenneth A. Johnson; David W. Taylor
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Crossref

Substrate Specificity and Kinetics of RNA Hydrolysis by SARS-CoV-2 NSP10/14 Exonuclease

ACS Bio & Med Chem Au
2022-12-21 | Journal article
DOI: 10.1021/acsbiomedchemau.2c00046
Contributors: Tyler L. Dangerfield; Kenneth A. Johnson
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Crossref

Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D CRISPR-Cas effector complex

2022-06-14 | Preprint
DOI: 10.1101/2022.06.13.496011
Contributors: Evan A. Schwartz; Jack P.K. Bravo; Luis A. Macias; Caitlyn L. McCafferty; Tyler L. Dangerfield; Jada N. Walker; Jennifer S. Brodbelt; Peter C. Fineran; Robert D. Fagerlund; David W. Taylor
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Crossref

Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid

Journal of Biological Chemistry
2022-01 | Journal article
DOI: 10.1016/j.jbc.2021.101451
Contributors: Tyler L. Dangerfield; Serdal Kirmizialtin; Kenneth A. Johnson
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Crossref

High throughput quantification of short nucleic acid samples by capillary electrophoresis with automated data processing

Analytical Biochemistry
2021-09 | Journal article
DOI: 10.1016/j.ab.2021.114239
Contributors: Tyler L. Dangerfield; Nathan Z. Huang; Kenneth A. Johnson
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Crossref

Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid

2021-07-13 | Other
DOI: 10.1101/2021.07.13.452224
Contributors: Tyler L. Dangerfield; Serdal Kirmizialtin; Kenneth A. Johnson
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Crossref

Expression and purification of tag-free SARS-CoV-2 RNA-dependent RNA polymerase in Escherichia coli

STAR Protocols
2021-03 | Journal article
DOI: 10.1016/j.xpro.2021.100357
Contributors: Tyler L. Dangerfield; Nathan Z. Huang; Kenneth A. Johnson
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Crossref

Conformational dynamics during high-fidelity DNA replication and translocation defined using a DNA polymerase with a fluorescent artificial amino acid

Journal of Biological Chemistry
2021-01-03 | Journal article
DOI: 10.1074/jbc.RA120.016617
Contributors: Tyler L. Dangerfield; Kenneth A. Johnson
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Crossref
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Optimized incorporation of an unnatural fluorescent amino acid affords measurement of conformational dynamics governing high-fidelity DNA replication

Journal of Biological Chemistry
2020 | Journal article
DOI: 10.1074/jbc.ra120.015557
Part of ISSN: 0021-9258
Contributors: Tyler L. Dangerfield; Kenneth A. Johnson
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search

Visible Light Mediated Bidirectional Control over Carbonic Anhydrase Activity in Cells and in Vivo Using Azobenzenesulfonamides

Journal of the American Chemical Society
2020-07-04 | Journal article
DOI: 10.1021/jacs.0c05383
Part of ISSN: 0002-7863
Contributors: Kanchan Aggarwal; Timothy P. Kuka; Mandira Banik; Brenda P. Medellin; Chinh Q. Ngo; Da Xie; Yohaan Fernandes; Tyler L. Dangerfield; Elva Ye; Bailey Bouley et al.
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search

Exploring the Reaction Mechanism of HIV Reverse Transcriptase with a Nucleotide Substrate

The Journal of Physical Chemistry B
2020-05-04 | Journal article
DOI: 10.1021/acs.jpcb.0c02632
Part of ISSN: 1520-6106
Contributors: Hao Wang; Nathan Huang; Tyler Dangerfield; Kenneth A. Johnson; Jiali Gao; Ron Elber
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search

Remdesivir is a Delayed Translocation Inhibitor of SARS CoV-2 Replication

SSRN Electronic Journal
Journal article
DOI: 10.2139/ssrn.3749649
Part of ISSN: 1556-5068
Contributors: Jack Bravo; Tyler L. Dangerfield; David W. Taylor; Kenneth A. Johnson
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search

Remdesivir is a delayed translocation inhibitor of SARS CoV-2 replication in vitro

Other
DOI: 10.1101/2020.12.14.422718
Contributors: Jack PK Bravo; Tyler L Dangerfield; David W Taylor; Kenneth A Johnson
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search

Remdesivir is Effective in Combating COVID-19 Because it is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase

SSRN Electronic Journal
Journal article
DOI: 10.2139/ssrn.3707278
Part of ISSN: 1556-5068
Contributors: Tyler L. Dangerfield; Nathan Z. Huang; Kenneth A. Johnson
Source: Self-asserted source
Tyler L. Dangerfield via Crossref Metadata Search
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Preferred source (of 3)‎

Peer review (1 review for 1 publication/grant)

Review activity for PloS one. (1)
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