Personal information

Japan

Activities

Employment (1)

Kanagawa Cancer Center Research Institute: Yokohama, Kanagawa, JP

2017-07-01 to present | Research Fellow (Division of Cancer Immunotherapy)
Employment
Source: Self-asserted source
Taku Kouro

Education and qualifications (8)

Takeda Pharmaceutical Company: Fujisawa, Kanagawa, JP

2012-04-01 to 2017-06-30 | Principal Scientist (Pharmaceutical Research Division)
Qualification
Source: Self-asserted source
Taku Kouro

National Institute of Biomedical Innovation: Ibaraki, Osaka, JP

2007-09-01 to 2012-03-31 | Project Leader (Department of Immunomodulation)
Qualification
Source: Self-asserted source
Taku Kouro

University of Toyama: Toyama, Toyama, JP

2007-04-01 to 2007-08-31 | Invited Associate Professor (Department of Immunobiology and Pharmacological Genetics)
Qualification
Source: Self-asserted source
Taku Kouro

Institute of Medical Science, University of Tokyo: Minato-ku, Tokyo, JP

2003-09-01 to 2007-03-31 | Associate Researcher (Department of Immunology)
Qualification
Source: Self-asserted source
Taku Kouro

Oklahoma Medical Research Foundation: Oklahoma City, OK, US

1999-04-01 to 2003-08-31 | Research Scientist / Senior Research Scientist (Immunobiology and Cancer Program)
Qualification
Source: Self-asserted source
Taku Kouro

Institute of Medical Science, University of Tokyo: Minato-ku, Tokyo, JP

1997-04-01 to 1999-03-31 | Research Fellow (Department of Immunology)
Qualification
Source: Self-asserted source
Taku Kouro

University of Tokyo: Tokyo, Tokyo, JP

1993-04-01 to 1997-03-31 | Ph.D. (Immunology) (Graduate School of Medicine)
Education
Source: Self-asserted source
Taku Kouro

Gunma University: Maebashi, Gunma, JP

1987-04-01 to 1993-03-31 (Faculty of Medicine)
Education
Source: Self-asserted source
Taku Kouro

Professional activities (1)

Kobe University: Kobe, Hyogo, JP

2008-04-01 to 2012-08-31 | Invited Professor
Invited position
Source: Self-asserted source
Taku Kouro

Works (50 of 68)

Items per page:
Page 1 of 2

Enhancing Mass spectrometry-based tumor immunopeptide identification: machine learning filter leveraging HLA binding affinity, aliphatic index and retention time deviation

Computational and Structural Biotechnology Journal
2024-12 | Journal article
Contributors: Feifei Wei; Taku Kouro; Yuko Nakamura; Hiroki Ueda; Susumu Iiizumi; Kyoko Hasegawa; Yuki Asahina; Takeshi Kishida; Soichiro Morinaga; Hidetomo Himuro et al.
Source: check_circle
Crossref

Prognostic Significance of Plasma Neutrophil Extracellular Trap Levels in Patients with Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors

Biomedicines
2024-08-12 | Journal article
Contributors: Shun Horaguchi; Yoshiro Nakahara; Yuka Igarashi; Taku Kouro; Feifei Wei; Kenta Murotani; Seiichi Udagawa; Naoko Higashijima; Norikazu Matsuo; Shuji Murakami et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Novel chimeric antigen receptor‐expressing T cells targeting the malignant mesothelioma‐specific antigen sialylated HEG1

International Journal of Cancer
2024-05-15 | Journal article
Contributors: Taku Kouro; Naoko Higashijima; Shun Horaguchi; Yasunobu Mano; Rika Kasajima; Huihui Xiang; Yuki Fujimoto; Hiroyuki Kishi; Hiroshi Hamana; Daisuke Hoshino et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Anti-human-TIGIT agonistic antibody ameliorates autoimmune diseases by inhibiting Tfh and Tph cells and enhancing Treg cells

Communications Biology
2023 | Journal article
Contributors: Kojima, Marenori; Suzuki, Katsuya; Takeshita, Masaru; Ohyagi, Masaki; Iizuka, Mana; Yamane, Humitsugu; Koga, Keiko; Kouro, Taku; Kassai, Yoshiaki; Yoshihara, Tomoki et al.
Source: check_circle
Web of Science Researcher Profile Sync

Clinical roles of soluble PD-1 and PD-L1 in plasma of NSCLC patients treated with immune checkpoint inhibitors

Cancer Immunology, Immunotherapy
2023 | Journal article
Contributors: Himuro, Hidetomo; Nakahara, Yoshiro; Igarashi, Yuka; Kouro, Taku; Higashijima, Naoko; Matsuo, Norikazu; Murakami, Shuji; Wei, Feifei; Horaguchi, Shun; Tsuji, Kayoko et al.
Source: check_circle
Web of Science Researcher Profile Sync

Machine learning for prediction of immunotherapeutic outcome in non-small-cell lung cancer based on circulating cytokine signatures

Journal for ImmunoTherapy of Cancer
2023-07 | Journal article
Contributors: Feifei Wei; Koichi Azuma; Yoshiro Nakahara; Haruhiro Saito; Norikazu Matsuo; Tomoyuki Tagami; Taku Kouro; Yuka Igarashi; Takaaki Tokito; Terufumi Kato et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Evaluation of X-ray and carbon-ion beam irradiation with chemotherapy for the treatment of cervical adenocarcinoma cells in 2D and 3D cultures

Cancer Cell International
2022 | Journal article
Contributors: Sekihara, Kazumasa; Himuro, Hidetomo; Saito, Nao; Ota, Yukihide; Kouro, Taku; Kusano, Yohsuke; Minohara, Shinichi; Hirayama, Ryoichi; Katoh, Hiroyuki; Sasada, Tetsuro et al.
Source: check_circle
Web of Science Researcher Profile Sync

Identification of HLA-binding neoepitopes through peptidome analysis with patient-derived xenografts

Cancer Science
2022 | Journal article
Contributors: Kouro, Taku; Kawamura, Takeshi; Ueda, Hiroki; Kishi, Hiroyuki; Aburatani, Hiroyuki; Sasada, Tetsuro
Source: check_circle
Web of Science Researcher Profile Sync

Exhaustion of CAR T cells: potential causes and solutions

Journal of Translational Medicine
2022-05-23 | Journal article
Contributors: Taku Kouro; Hidetomo Himuro; Tetsuro Sasada
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Efficient identification of HLA-binding neoepitopes through peptidome analysis with clinical tumor tissues

Cancer Science
2021 | Journal article
Contributors: Hasegawa, Kyoko; Kouro, Taku; Igarashi, Yuka; Kawamura, Takeshi; Ueda, Hiroki; Aburatani, Hiroyuki; Sasada, Tetsuro
Source: check_circle
Web of Science Researcher Profile Sync

Identification of novel HLA class II-restricted neoantigens derived from driver mutations

Cancers
2019 | Journal article
EID:

2-s2.0-85063333222

Part of ISSN: 20726694
Contributors: Iiizumi, S.; Ohtake, J.; Murakami, N.; Kouro, T.; Kawahara, M.; Isoda, F.; Hamana, H.; Kishi, H.; Nakamura, N.; Sasada, T.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Prospects for a personalized peptide vaccine against lung cancer

Expert Review of Vaccines
2019 | Journal article
EID:

2-s2.0-85069780416

Part of ISSN: 17448395 14760584
Contributors: Nakahara, Y.; Kouro, T.; Igarashi, Y.; Kawahara, M.; Sasada, T.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Fetal lymphoid progenitors become restricted to B-1 fates coincident with IL-7Rα expression

PLoS ONE
2016 | Journal article
EID:

2-s2.0-84993961092

Contributors: Iida, R.; Shinoda, K.; Hayano, Y.; Nagai, Y.; Takatsu, K.; Kouro, T.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Satb1 Protein Directs Hematopoietic Stem Cell Differentiation toward Lymphoid Lineages

Immunity
2013 | Journal article
EID:

2-s2.0-84879588905

Contributors: Satoh, Y.; Yokota, T.; Sudo, T.; Kondo, M.; Lai, A.; Kincade, P.; Kouro, T.; Iida, R.; Kokame, K.; Miyata, T. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Identification of Innate IL-5-Producing Cells and Their Role in Lung Eosinophil Regulation and Antitumor Immunity

Journal of Immunology
2012 | Journal article
EID:

2-s2.0-84863393516

Contributors: Ikutani, M.; Yanagibashi, T.; Ogasawara, M.; Tsuneyama, K.; Yamamoto, S.; Hattori, Y.; Kouro, T.; Itakura, A.; Nagai, Y.; Takaki, S. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Participation of B-1 cells in the nasal influenza vaccine-induced antibody production

The Journal of Immunology
2011 | Journal article
Contributors: Kouro, Taku; Iida, Ryuji; Hattori, Yuki; Shinoda, Kaori
Source: check_circle
Web of Science Researcher Profile Sync

Satb1 Determines Hematopoietic Stem Cell Differentiation Toward the Lymphoid Lineages

Blood
2011 | Journal article
Contributors: Satoh, Yusuke; Yokota, Takafumi; Kondo, Motonari; Kincade, Paul W.; Kouro, Taku; Iida, Ryuji; Kokame, Koichi; Miyata, Toshiyuki; Sudo, Takao; Tanaka, Hirokazu et al.
Source: check_circle
Web of Science Researcher Profile Sync

Chapter 6 Interleukin 5 in the Link Between the Innate and Acquired Immune Response

Advances in Immunology
2009 | Book
EID:

2-s2.0-60449105149

Contributors: Takatsu, K.; Kouro, T.; Nagai, Y.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Expression of IL-5Rα on B-1 cell progenitors in mouse fetal liver and involvement of Bruton's tyrosine kinase in their development

Immunology Letters
2009 | Journal article
EID:

2-s2.0-67349122298

Contributors: Kouro, T.; Ikutani, M.; Kariyone, A.; Takatsu, K.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

IL-5- and eosinophil-mediated inflammation: From discovery to therapy

International Immunology
2009 | Journal article
EID:

2-s2.0-70450175479

Contributors: Kouro, T.; Takatsu, K.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Participation of intercellular adhesion molecule-2 (CD102) in B lymphopoiesis

Immunology Letters
2008 | Journal article
EID:

2-s2.0-50449099273

Contributors: Yamashita, Y.; Kouro, T.; Miyake, K.; Takatsu, K.; Kido, M.A.; Tanaka, T.; Goto, M.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis

Journal of Immunology
2008 | Journal article
EID:

2-s2.0-58749092353

Contributors: Yokota, T.; Oritani, K.; Garrett, K.P.; Kouro, T.; Nishida, M.; Takahashi, I.; Ichii, M.; Satoh, Y.; Kincade, P.W.; Kanakura, Y.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

Journal of Experimental Medicine
2007 | Journal article
EID:

2-s2.0-36549072863

Contributors: Takahashi, K.; Shibata, T.; Akashi-Takamura, S.; Kiyokawa, T.; Wakabayashi, Y.; Tanimura, N.; Kobayashi, T.; Matsumoto, F.; Fukui, R.; Kouro, T. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

IL-5-induced hypereosinophilia suppiresses the antigen-induced immune response via a TGF-beta-dependent mechanism

The Journal of Immunology
2007 | Journal article
Contributors: Nakagome, Kazuyuki; Dohi, Makoto; Okunishi, Katsuhide; Tanaka, Ryoichi; Kouro, Taku; Kano, Mitsunobu R.; Miyazono, Kohei; Miyazaki, Jun-ichi; Takatsu, Kiyoshi; Yamamoto, Kazuhiko
Source: check_circle
Web of Science Researcher Profile Sync

IL-5-induced hypereosinophilia suppresses the antigen-induced immune response via a TGF-β-dependent mechanism

Journal of Immunology
2007 | Journal article
EID:

2-s2.0-34250856774

Contributors: Nakagome, K.; Dohi, M.; Okunishi, K.; Tanaka, R.; Kouro, T.; Kano, M.R.; Miyazono, K.; Miyazaki, J.-I.; Takatsu, K.; Yamamoto, K.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier

SFRP1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis

Blood
2007 | Journal article
Contributors: Yokota, Takafumi; Oritani, Kenji; Garrett, Karla P.; Kouro, Taku; Nishida, Makoto; Takahashi, Isao; Ichii, Michiko; Matsumura, Itaru; Kincade, Paul W.; Kanakura, Yuzuru
Source: check_circle
Web of Science Researcher Profile Sync

A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4

Journal of Immunology
2006 | Journal article
EID:

2-s2.0-33746214788

Contributors: Wakabayashi, Y.; Kobayashi, M.; Akashi-Takamura, S.; Tanimura, N.; Konno, K.; Takahashi, K.; Ishii, T.; Mizutani, T.; Iba, H.; Kouro, T. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Interleukin 5 plays an essential role in elicitation of contact sensitivity through dual effects on eosinophils and B-1 cells

International Archives of Allergy and Immunology
2006 | Journal article
EID:

2-s2.0-33745096612

Contributors: Itakura, A.; Kikuchi, Y.; Kouro, T.; Ikutani, M.; Takaki, S.; Askenase, P.W.; Takatsu, K.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential

Journal of Immunology
2006 | Journal article
EID:

2-s2.0-33747781772

Contributors: Perry, S.S.; Welner, R.S.; Kouro, T.; Kincade, P.W.; Sun, X.-H.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment

Immunity
2006 | Journal article
EID:

2-s2.0-33744978765

Contributors: Nagai, Y.; Garrett, K.P.; Ohta, S.; Bahrun, U.; Kouro, T.; Akira, S.; Takatsu, K.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

In vitro differentiation and measurement of B cell progenitor activity in culture.

Current protocols in immunology / edited by John E. Coligan ... [et al.]
2005 | Journal article
EID:

2-s2.0-45849129840

Contributors: Kouro, T.; Yokota, T.; Welner, R.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier

Isolation of prolymphocytes from bone marrow and fetal liver.

Current protocols in immunology / edited by John E. Coligan ... [et al.]
2005 | Journal article
EID:

2-s2.0-45849108797

Contributors: Kouro, T.; Yokota, T.; Welner, R.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier

Measurement of natural killer cell progenitor activity in culture.

Current protocols in immunology / edited by John E. Coligan ... [et al.]
2005 | Journal article
EID:

2-s2.0-45849108795

Contributors: Kouro, T.; Yokota, T.; Welner, R.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier

Possible paticipation of interleukin-5 in the early differentiation of B-1 cells

The FASEB Journal
2005 | Journal article
Contributors: Kouro, T; Ikutani, M; Takatsu, K
Source: check_circle
Web of Science Researcher Profile Sync

Role of IL-5 in the innate immune system and disease control

International Congress Series
2005 | Book
EID:

2-s2.0-33646443976

Contributors: Takatsu, K.; Moon, B.-g.; Itakura, A.; Tsukamoto, Y.; Horikawa, K.; Ikutani, M.; Kouro, T.; Takaki, S.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier

Roles of notch receptors in lymphopoiesis initiated with fetal and adult progenitors

The FASEB Journal
2004 | Journal article
Contributors: Huang, JX; Garrett, KP; Yokota, T; Kouro, T; Schmitt, TM; Zuniga-Pflucker, JC; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

Src Homology 2-containing 5-Inositol Phosphatase (SHIP) Suppresses an Early Stage of Lymphoid Cell Development through Elevated Interleukin-6 Production by Myeloid Cells in Bone Marrow

Journal of Experimental Medicine
2004 | Journal article
EID:

2-s2.0-1642581122

Contributors: Nakamura, K.; Kouro, T.; Kincade, P.W.; Malykhin, A.; Maeda, K.; Coggeshal, K.M.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Adiponectin, a Fat Cell Product, Influences the Earliest Lymphocyte Precursors in Bone Marrow Cultures by Activation of the Cyclooxygenase-Prostaglandin Pathway in Stromal Cells

Journal of Immunology
2003 | Journal article
EID:

2-s2.0-10744223271

Contributors: Yokota, T.; Meka, C.S.R.; Kouro, T.; Medina, K.L.; Igarashi, H.; Takahashi, M.; Oritani, K.; Funahashi, T.; Tomiyama, Y.; Matsuzawa, Y. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Early divergence of T cell progenitors from B and NK cell progenitors in bone marrow

The FASEB Journal
2003 | Journal article
Contributors: Kouro, T; Igarashi, H; Sakaguchi, N; Rothenberg, EV; Owen, JJT; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction

Nature Immunology
2003 | Journal article
EID:

2-s2.0-0037341617

Contributors: Suzuki, H.; Matsuda, S.; Terauchi, Y.; Fujiwara, M.; Ohteki, T.; Asano, T.; Behrens, T.W.; Kouro, T.; Takatsu, K.; Kadowaki, T. et al.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

RAG-1 gene expression signals loss of myelo-erythroid potential in fetal lymphocyte progenitors, that differ substantially from their adult counterparts

The FASEB Journal
2003 | Journal article
Contributors: Yokota, T; Kouro, T; Hirose, J; Igarashi, H; Gregory, SC; Garrett, KP; Sakaguchi, N; Owen, JJT; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

Unique properties of fetal lymphoid progenitors identified according to RAG1 gene expression

Immunity
2003 | Journal article
EID:

2-s2.0-0141567542

Contributors: Yokota, T.; Kouro, T.; Hirose, J.; Igarashi, H.; Garrett, K.P.; Gregory, S.C.; Sakaguchi, N.; Owen, J.J.T.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

A developing picture of lymphopoiesis in bone marrow

Immunological Reviews
2002 | Journal article
EID:

2-s2.0-0036862533

Contributors: Hirose, J.; Kouro, T.; Igarashi, H.; Yokota, T.; Sakaguchi, N.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

A role of estrogen receptor alpha in the regulation of B lymphopoiesis?

The FASEB Journal
2002 | Journal article
Contributors: Kouro, T; Harris, HA; Katzenellenbogen, JA; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

Adiponectin, a fat cell product, indirectly influences early lymphocyte precursors through a cyclooxygenase-2 dependent mechanism

The FASEB Journal
2002 | Journal article
Contributors: Yokota, T; Meka, CSR; Kouro, T; Medina, KL; Oritani, K; Tomiyama, Y; Matsuzawa, Y; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

Lymphoid lineage cells in adult murine bone marrow diverge from those of other blood cells at an early, hormone-sensitive stage

Seminars in immunology
2002 | Journal article
EID:

2-s2.0-19044397719

Contributors: Kincade, P.W.; Igarashi, H.; Medina, K.L.; Kouro, T.; Yokota, T.; Rossi, M.I.D.; Owen, J.J.; Garrett, K.P.; Sun, X.-H.; Sakaguchi, N.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Nature or nurture? Steady-state lymphocyte formation in adults does not recapitulate ontogeny

Immunological Reviews
2002 | Journal article
EID:

2-s2.0-0036749790

Contributors: Kincade, P.W.; Owen, J.J.T.; Igarashi, H.; Kouro, T.; Yokota, T.; Rossi, M.I.D.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

Relationships between early B- and NK-lineage lymphocyte precursors in bone marrow

Blood
2002 | Journal article
EID:

2-s2.0-0037111566

Contributors: Kouro, T.; Kumar, V.; Kincade, P.W.
Source: Self-asserted source
Taku Kouro via Scopus - Elsevier
grade
Preferred source (of 2)‎

A developmental switch in regulation of B lymphopoiesis

The FASEB Journal
2001 | Journal article
Contributors: Igarashi, H; Kouro, T; Medina, KL; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync

Adiponectin, an adipocyte-specific secretory protein, inhibits B lymphopoiesis in culture

The FASEB Journal
2001 | Journal article
Contributors: Yokota, T; Oritani, K; Kouro, T; Meka, R; Medina, KL; Tomiyama, Y; Matsuzawa, Y; Kincade, PW
Source: check_circle
Web of Science Researcher Profile Sync
Items per page:
Page 1 of 2

Peer review (30 reviews for 14 publications/grants)

Review activity for Antibodies. (1)
Review activity for Cancer medicine. (2)
Review activity for Cancer science. (1)
Review activity for Cancers. (3)
Review activity for Cells. (3)
Review activity for Diagnostics. (2)
Review activity for Immuno. (1)
Review activity for International journal of cancer. (2)
Review activity for International journal of molecular sciences. (7)
Review activity for Journal for immunotherapy of cancer. (2)
Review activity for npj precision oncology. (1)
Review activity for Pharmaceutics. (2)
Review activity for Translational lung cancer research. (1)
Review activity for Vaccines. (2)