Personal information

Other IDs

Loop profile: 766809

Keywords

Blood-brain barrier, Ischaemic stroke, Cerebrospinal fluid, Intracranial pressure

Countries

United Kingdom

Activities

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Education and qualifications (1)

King's College London: London, GB

PhD (Neuroscience/Physiology)
Education
Source: Self-asserted source
Adjanie Patabendige

Works (38)

Blood–brain barrier disruption in dementia: Nano‐solutions as new treatment options

The European journal of neuroscience
2023-12-28 | Journal article | Author
DOI: 10.1111/ejn.16229
DOI: 10.1111/ejn.16229
SOURCE-WORK-ID:

840a11ad-12d1-4fee-8602-845253562625

PMID: 38154805
EID:

2-s2.0-85180876733
Contributors: Ceinwyn G Cooper; Konstantinos N Kafetzis; Adjanie Patabendige; Aristides Tagalakis
Source: check_circle
Edge Hill University

EXTH-36. COMBINING ONC201 AND PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA (DMG); THE PRECLINICAL RESULTS UNDERPINNING THE INTERNATIONAL PHASE II CLINICAL TRIAL (NCT05009992)

Neuro-Oncology
2023-11-10 | Journal article | Author
DOI: 10.1093/neuonc/noad179.0889
SOURCE-WORK-ID:

3ebec889-be07-4239-aad9-3a0651387a6b
Contributors: Evangeline Jackson; Ryan Duchatel; Dilana Staudt; Mika Persson; Abdul Mannan; Sridevi Yadavilli; Sarah Parackal; Shaye Game; Wai Chin Chong; W Samantha Jayasekara et al.
Source: check_circle
Edge Hill University

ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.

Cancer research
2023-05 | Journal article
DOI: 10.1158/0008-5472.can-23-0186
PMID: 37145169
Contributors: Jackson ER; Duchatel RJ; Staudt DE; Persson ML; Mannan A; Yadavilli S; Parackal S; Game S; Chong WC; Jayasekara WSN et al.
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

The role of the blood–brain barrier during neurological disease and infection

Biochemical Society Transactions
2023-04-26 | Journal article
DOI: 10.1042/BST20220830
Contributors: Adjanie Patabendige; Damir Janigro
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Editorial: Cerebrospinal fluid dynamics and intracranial pressure elevation–Novel insights on molecular and physiological mechanisms, and implications for neurological disease

Frontiers in Molecular Neuroscience
2022 | Journal article
DOI: 10.3389/fnmol.2022.1119980
EID:

2-s2.0-85146123500

Part of ISSN: 16625099
Contributors: Patabendige, A.; Vinje, V.; Stoodley, M.
Source: Self-asserted source
Adjanie Patabendige via Scopus - Elsevier

Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke

Neural Regeneration Research
2022-04-29 | Journal article | Author
SOURCE-WORK-ID:

335762be-f09d-4d25-8284-7fd77125d283

EID:

2-s2.0-85132261059
Contributors: Adjanie Patabendige; Ruoli Chen
Source: check_circle
Edge Hill University
grade
Preferred source (of 3)‎

An Improved In Vitro Porcine Blood-Brain Barrier Model for Permeability Screening and Functional Studies.

Methods in molecular biology (Clifton, N.J.)
2022-01 | Journal article
DOI: 10.1007/978-1-0716-2289-6_7
PMID: 35733042
Contributors: Patabendige A
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Hypothermia and rewarming prior to reperfusion, prevents intracranial pressure elevation after ischaemic stroke in rats: an investigation to define the importance of cooling during reperfusion

ResearchSquare
2021 | Other
DOI: 10.21203/rs.3.rs-846595
EID:

2-s2.0-85132482365
Contributors: Omileke, D.; Azarpeykan, S.; Bothwell, S.W.; Pepperall, D.; Beard, D.J.; Coupland, K.; Patabendige, A.; Spratt, N.J.
Source: Self-asserted source
Adjanie Patabendige via Scopus - Elsevier

Short-duration hypothermia induction in rats using models for studies examining clinical relevance and mechanisms

Journal of Visualized Experiments
2021 | Journal article
DOI: 10.3791/62325
EID:

2-s2.0-85102550670

Part of ISSN: 1940087X
Contributors: Omileke, D.; Bothwell, S.; Beard, D.J.; Mackovski, N.; Azarpeykan, S.; Coupland, K.; Patabendige, A.; Spratt, N.
Source: Self-asserted source
Adjanie Patabendige via Scopus - Elsevier
grade
Preferred source (of 2)‎

Decreased Intracranial Pressure Elevation and Cerebrospinal Fluid Outflow Resistance: A Potential Mechanism of Hypothermia Cerebroprotection Following Experimental Stroke

Brain Sciences
2021-11 | Journal article | Author
DOI: 10.3390/brainsci11121589
Contributors: Daniel Omileke; Steven W. Bothwell; Debbie Pepperall; Daniel Beard; Kirsten Coupland; Adjanie Patabendige; Neil J. Spratt
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats

Scientific Reports
2021-11-16 | Journal article | Author
DOI: 10.1038/s41598-021-01838-7
SOURCE-WORK-ID:

bfdf61be-b511-407a-a8c1-bde1ae9d485f

EID:

2-s2.0-85119125918
Contributors: Daniel Omileke; Sara Azarpeykan; Steven William Bothwell; Debbie Pepperall; Daniel J. Beard; Kirsten Coupland; Adjanie Patabendige; Neil J. Spratt
Source: check_circle
Edge Hill University

Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats

Frontiers in Neurology
2021-09-20 | Journal article | Author
DOI: 10.3389/fneur.2021.684353
SOURCE-WORK-ID:

bf47bf50-f938-42f9-a094-ec36e4b76454

EID:

2-s2.0-85116407719
Contributors: Daniel Omileke; Debbie Gai Pepperall; Steven W Bothwell; Nikolce Mackovski; Sara Azarpeykan; Daniel J. Beard; Kirsten Coupland; Adjanie Patabendige; Neil J Spratt
Source: check_circle
Edge Hill University

CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats

Brain Sciences
2021-08 | Journal article | Author
DOI: 10.3390/brainsci11091117
Contributors: Steven W Bothwell; Daniel Omileke; Adjanie Patabendige; Neil J Spratt
Source: check_circle
Multidisciplinary Digital Publishing Institute

Hypothermia and rewarming prior to reperfusion, prevents intracranial pressure elevation after ischaemic stroke in rats: an investigation to define the importance of cooling during reperfusion

2021-08 | Preprint
DOI: 10.21203/rs.3.rs-846595/v1
PPR: PPR388873
Contributors: Omileke D; Azarpeykan S; Bothwell SW; Pepperall D; Beard DJ; Coupland K; Patabendige A; Spratt NJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia

Frontiers in Molecular Neuroscience
2021-08-09 | Journal article | Author
DOI: 10.3389/fnmol.2021.712779
SOURCE-WORK-ID:

29036bb1-163c-4249-8b08-5db8133fc516

EID:

2-s2.0-85113783002
Contributors: Steven W. Bothwell; Daniel Omileke; Rebecca J. Hood; Debbie Gai Pepperall; Sara Azarpeykan; Adjanie Patabendige; Neil J. Spratt
Source: check_circle
Edge Hill University

Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?

Open Biology
2021-04 | Journal article
DOI: 10.1098/rsob.200396
Contributors: Ritambhara Aryal; Adjanie Patabendige
Source: check_circle
Crossref

Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke

International Journal of Molecular Sciences
2021-04-20 | Journal article
DOI: 10.3390/ijms22084280
Contributors: Adjanie Patabendige; Ayesha Singh; Stuart Jenkins; Jon Sen; Ruoli Chen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Spinal cerebrospinal fluid flow is increased in rats with elevated intracranial pressure 18 hours after cortical ischaemic stroke

ResearchSquare
2020 | Other
DOI: 10.21203/rs.3.rs-84123
EID:

2-s2.0-85145758412
Contributors: Bothwell, S.W.; Omileke, D.; Pepperall, D.-G.; Patabendige, A.; Spratt, N.J.
Source: Self-asserted source
Adjanie Patabendige via Scopus - Elsevier

Spinal cerebrospinal fluid flow is increased in rats with elevated intracranial pressure 18 hours after cortical ischaemic stroke

2020-10 | Preprint
DOI: 10.21203/rs.3.rs-84123/v1
OTHER-ID:

PPR221140
Contributors: Bothwell SW; Omileke D; Pepperall D; Patabendige A; Spratt NJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

Fluids and Barriers of the CNS
2019-12 | Journal article
DOI: 10.1186/s12987-019-0129-6
Contributors: Steven William Bothwell; Damir Janigro; Adjanie Patabendige
Source: check_circle
Crossref

Correction to: A26 Cerebrospinal fluid outflow resistance is increased following small-moderate ischaemic stroke.

Fluids and barriers of the CNS
2019-07 | Journal article
PMC: PMC6621977
Contributors: Patabendige A; MacKovski N; Pepperall D; Hood R; Spratt N
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Cerebrospinal fluid outflow resistance is increased following small‑moderate ischaemic stroke

Fluids and Barriers of the CNS
2019-06 | Conference paper
Part of DOI: 10.1186/s12987-019-0135-8
Part of ISSN: 2045-8118
Source: Self-asserted source
Adjanie Patabendige

DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Neuro-oncology
2019-04 | Journal article
PMC: PMC6477226
Contributors: Duchatel R; Jackson E; Patabendige A; Cain J; Tsoli M; Monje M; Alvaro F; Ziegler D; Dun M
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Japanese encephalitis virus infection increases blood-brain barrier permeability in a human model by inducing a strong pro-inflammatory endothelial response

Mendeley
2018 | Dataset
DOI: 10.17632/hzzbg2z7bm.1
Contributors: Adjanie Patabendige
Source: check_circle
DataCite

Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model

Molecular and Cellular Neuroscience
2018-06 | Journal article
DOI: 10.1016/j.mcn.2018.04.002
Contributors: Adjanie Patabendige; Benedict D. Michael; Alister G. Craig; Tom Solomon
Source: check_circle
Crossref

Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein.

2015-08 | Journal article
DOI: 10.1128/jvi.03645-14
PMID: 25972559
PMC: PMC4505677
Contributors: Ferguson MC; Saul S; Fragkoudis R; Weisheit S; Cox J; Patabendige A; Sherwood K; Watson M; Merits A; Fazakerley JK
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Semliki Forest virus strain SFV6, complete genome

National Library of Medicine (US), National Center for Biotechnology Information
2015-08-06 | Dataset
Source: Self-asserted source
Adjanie Patabendige

Arthropod-borne viral encephalititdes

Infections of the Central Nervous System
2014 | Book chapter
Part of ISBN: 978-1451173727
Source: Self-asserted source
Adjanie Patabendige

Primary porcine brain microvessel endothelial cell isolation and culture.

2014-10 | Journal article
DOI: 10.1002/0471142301.ns0327s69
PMID: 25297692
Contributors: Patabendige A; Abbott NJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Arthropod-borne viral encephalitides

Arthropod-borne viral encephalitides
2014-05 | Book chapter
ISBN: 978-1451173727
Source: check_circle
Researchfish

EFFECT OF TYSABRI AND AQP4-IGG ON AN IN-VITRO MODEL OF BBB

Journal of Neurology, Neurosurgery & Psychiatry
2014-01 | Journal article
DOI: 10.1136/jnnp-2014-309236.162
Source: check_circle
Researchfish
grade
Preferred source (of 2)‎

THE BBB IN ENCEPHALITIS: INFLAMMATION & A ROLE FOR STEROIDS?

Journal of Neurology, Neurosurgery & Psychiatry
2014-01 | Journal article
DOI: 10.1136/jnnp-2014-309236.124
Source: check_circle
Researchfish
grade
Preferred source (of 2)‎

A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells.

2013-07 | Journal article
DOI: 10.1016/j.brainres.2013.04.006
PMID: 23603406
PMC: PMC3694295
Contributors: Patabendige A; Skinner RA; Morgan L; Abbott NJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance.

2013-07 | Journal article
DOI: 10.1016/j.brainres.2012.06.057
PMID: 22789905
PMC: PMC3694297
Contributors: Patabendige A; Skinner RA; Abbott NJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

The value of in vitro models of the blood-brain barrier and their uses.

Alternatives to laboratory animals : ATLA
2012-01 | Journal article
PMID: 23398338
WOSUID:

000208852300017
Source: check_circle
Researchfish
grade
Preferred source (of 2)‎

Toward a humanised alternative to the use of laboratory animals for blood-brain barrier research.

Alternatives to laboratory animals : ATLA
2012-01 | Journal article
PMID: 23215666
WOSUID:

000312414600025
Source: check_circle
Researchfish
grade
Preferred source (of 2)‎

Structure and function of the blood-brain barrier.

2010-01 | Journal article
DOI: 10.1016/j.nbd.2009.07.030
PMID: 19664713
Contributors: Abbott NJ; Patabendige AA; Dolman DE; Yusof SR; Begley DJ
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Assays to predict drug permeation across the blood-brain barrier, and distribution to brain.

2008-11 | Journal article
DOI: 10.2174/138920008786485182
PMID: 18991587
Contributors: Abbott NJ; Dolman DE; Patabendige AK
Source: Self-asserted source
Adjanie Patabendige via Europe PubMed Central

Peer review (6 reviews for 5 publications/grants)

Review activity for Cells. (1)
Review activity for Fluids and barriers of the CNS. (2)
Review activity for International journal of molecular sciences. (1)
Review activity for Proteomes. (1)
Review activity for UK Research and Innovation (1)
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