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Works (37)

Transcriptional regulatory program controlled by MYB in T-cell acute lymphoblastic leukemia

Leukemia
2024-12 | Journal article
DOI: 10.1038/s41375-024-02455-9
Contributors: Xiaoman Shao; Rui Yokomori; Jolynn Zu Lin Ong; Haoqing Shen; Dennis Kappei; Leilei Chen; Allen Eng Juh Yeoh; Shi Hao Tan; Takaomi Sanda
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Crossref

Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia

Leukemia
2024-09 | Journal article
DOI: 10.1038/s41375-024-02331-6
Contributors: Hyoju Kim; Tze King Tan; Dean Zi Yang Lee; Xiao Zi Huang; Jolynn Zu Lin Ong; Michelle A. Kelliher; Allen Eng Juh Yeoh; Takaomi Sanda; Shi Hao Tan
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Crossref

Deciphering the regulatory landscape of murine splenic response to anemic stress at single-cell resolution

Blood Advances
2024-04-09 | Journal article
DOI: 10.1182/bloodadvances.2023011965
Contributors: Chong Yang; Rui Yokomori; Lee Hui Chua; Shi Hao Tan; Mun Yee Koh; Haruhito Totani; Takaomi Sanda; Toshio Suda
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Crossref

Correction to: TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia

Leukemia
2024-03 | Journal article
DOI: 10.1038/s41375-023-02125-2
Contributors: Shi Hao Tan; Tze King Tan; Rui Yokomori; Minghui Liao; Xiao Zi Huang; Allen Eng Juh Yeoh; Takaomi Sanda
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Crossref

ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors

Cell Reports
2023-12 | Journal article
DOI: 10.1016/j.celrep.2023.113541
Contributors: Lu Wang; Tze King Tan; Hyoju Kim; Dennis Kappei; Shi Hao Tan; A. Thomas Look; Takaomi Sanda
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Crossref

TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia

Leukemia
2023-10 | Journal article
DOI: 10.1038/s41375-023-01993-y
Contributors: Shi Hao Tan; Tze King Tan; Rui Yokomori; Minghui Liao; Xiao Zi Huang; Allen Eng Juh Yeoh; Takaomi Sanda
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Crossref

Data from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.c.6570596
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Data from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.c.6570596.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Supplementary Figures from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582487
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Figures from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582487.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Supplementary Materials and Methods from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582484
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Materials and Methods from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582484.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 1 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582481
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 1 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582481.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 2 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582478
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 2 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582478.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 3 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582475
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 3 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582475.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 4 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582472
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 4 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582472.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 5 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582469
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Supplementary Table 5 from Super Enhancer-Mediated Upregulation of <i>HJURP</i> Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

2023-04-10 | Preprint
DOI: 10.1158/0008-5472.22582469.v1
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47

Journal of Experimental Medicine
2022-12-05 | Journal article
DOI: 10.1084/jem.20220685
Contributors: Chong Yang; Rui Yokomori; Lee Hui Chua; Shi Hao Tan; Darren Qiancheng Tan; Kenichi Miharada; Takaomi Sanda; Toshio Suda
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Crossref

Lineage- and Stage-Specific Oncogenicity of IRF4

Experimental Hematology
2022-10 | Journal article
DOI: 10.1016/j.exphem.2022.07.300
Contributors: Stella Amanda; Tze King Tan; Shinsuke Iida; Takaomi Sanda
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Crossref

Requirement for TP73 and genetic alterations originating from its intragenic super-enhancer in adult T-cell leukemia

Leukemia
2022-09 | Journal article
DOI: 10.1038/s41375-022-01655-5
Contributors: Jolynn Zu Lin Ong; Rui Yokomori; Regina Wan Ju Wong; Tze King Tan; Ryuzo Ueda; Takashi Ishida; Shinsuke Iida; Takaomi Sanda
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Crossref

Loss of METTL3 attenuates blastic plasmacytoid dendritic cell neoplasm response to PRMT5 inhibition via IFN signaling

Blood Advances
2022-09-27 | Journal article
DOI: 10.1182/bloodadvances.2021006306
Contributors: Malini Rethnam; Darren Qiancheng Tan; Shi Hao Tan; Jia Li; Rui Yokomori; Ying Li; Henry Yang; Takaomi Sanda; Toshio Suda
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Crossref

IRF4 as an Oncogenic Master Transcription Factor

Cancers
2022-09-02 | Journal article
DOI: 10.3390/cancers14174314
Contributors: Regina Wan Ju Wong; Jolynn Zu Lin Ong; Madelaine Skolastika Theardy; Takaomi Sanda
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Crossref
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Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

Cancer Research
2022-02-01 | Journal article
DOI: 10.1158/0008-5472.CAN-21-0921
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Yongxia Chen; Jing-Yuan Chooi; Takaomi Sanda; Melissa J. Fullwood; Sinan Xiong; Sabrina H.M. Toh et al.
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Crossref

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma

Blood Cancer Journal
2021-02-12 | Journal article
DOI: 10.1038/s41408-021-00421-7
Contributors: Yunlu Jia; Jianbiao Zhou; Tze King Tan; Tae-Hoon Chung; Regina Wan Ju Wong; Jing-Yuan Chooi; Julia Sze Lynn Lim; Takaomi Sanda; Melissa Ooi; Sanjay De Mel et al.
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Crossref

Oncogenic transcriptional program driven by TAL1 in T-cell acute lymphoblastic leukemia

International Journal of Hematology
2019-01-25 | Journal article
DOI: 10.1007/s12185-018-2518-z
Contributors: Tze King Tan; Chujing Zhang; Takaomi Sanda
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Crossref

Identification of novel lncRNAs regulated by the TAL1 complex in T-cell acute lymphoblastic leukemia

Leukemia
2018-10-26 | Journal article
DOI: 10.1038/s41375-018-0110-4
Contributors: Phuong Cao Thi Ngoc; Shi Hao Tan; Tze King Tan; Min Min Chan; Zhenhua Li; Allen. E. J. Yeoh; Daniel G Tenen; Takaomi Sanda
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Crossref

Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia

Molecules
2018-05-02 | Journal article
DOI: 10.3390/molecules23051057
Contributors: Regina Wan Ju Wong; Takashi Ishida; Takaomi Sanda
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Crossref
grade
Preferred source (of 2)‎

ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis

Genes & Development
2017-12-01 | Journal article
DOI: 10.1101/gad.302646.117
Contributors: Wei Zhong Leong; Shi Hao Tan; Phuong Cao Thi Ngoc; Stella Amanda; Alice Wei Yee Yam; Wei-Siang Liau; Zhiyuan Gong; Lee N. Lawton; Daniel G. Tenen; Takaomi Sanda
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Crossref

RUNX1 in T-ALL: tumor suppressive or oncogenic?

Blood
2017-10-12 | Journal article
DOI: 10.1182/blood-2017-08-802181
Contributors: Takaomi Sanda
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Crossref

Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia

Leukemia
2017-08 | Journal article
DOI: 10.1038/leu.2016.392
Contributors: W S Liau; S H Tan; P C T Ngoc; C Q Wang; V Tergaonkar; H Feng; Z Gong; M Osato; A T Look; T Sanda
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Crossref

HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia

Leukemia
2016-01 | Journal article
DOI: 10.1038/leu.2015.222
Contributors: K Akahane; T Sanda; M R Mansour; T Radimerski; D J DeAngelo; D M Weinstock; A T Look
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Crossref

RUNX1 point mutations potentially identify a subset of early immature T-cell acute lymphoblastic leukaemia that may originate from differentiated T-cells

Gene
2014-07 | Journal article
DOI: 10.1016/j.gene.2014.04.074
Contributors: Michelle Meng Huang Mok; Linsen Du; Chelsia Qiuxia Wang; Vinay Tergaonkar; Te Chih Liu; Shirley Kow Yin Kham; Takaomi Sanda; Allen Eng-Juh Yeoh; Motomi Osato
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Peer review (14 reviews for 7 publications/grants)

Review activity for Cell reports. (1)
Review activity for Communications biology. (1)
Review activity for Genome medicine. (1)
Review activity for International journal of oral science. (1)
Review activity for Leukemia (4)
Review activity for Nature communications (4)
Review activity for Oncogene. (2)
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