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Pharmacist and passionate Natural Product Chemist

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Employment (5)

Freie Universität Berlin: Berlin, DE

2023-08-01 to present | Professor (Institute of Pharmacy)
Employment
Source: Self-asserted source
Timo H. J. Niedermeyer

Martin Luther University Halle-Wittenberg: Halle, DE

2017-04 to 2023-07-31 | Professor (Institute for Pharmacy)
Employment
Source: Self-asserted source
Timo H. J. Niedermeyer

Eberhard Karls Universität Tübingen: Tübingen, Baden-Württemberg, DE

2013-11 to 2017-03 | Assistant Professor (Institute for Microbiology and Infection Medicine)
Employment
Source: Self-asserted source
Timo H. J. Niedermeyer

Cyano Biotech GmbH: Berlin, Berlin, DE

2008-09 to 2013-11 | Head of Natural Product R&D (Natural Product R&D)
Employment
Source: Self-asserted source
Timo H. J. Niedermeyer

Riemser Arzneimittel AG: Greifswald, Mecklenburg-Vorpommern, DE

2004-12 to 2008-08 | Research Scientist, Team Leder Stability Studies (CMC)
Employment
Source: Self-asserted source
Timo H. J. Niedermeyer

Education and qualifications (4)

Universität Leipzig: Leipzig, Sachsen, DE

2005-09 to 2007-10 (Chemistry)
Education
Source: Self-asserted source
Timo H. J. Niedermeyer

Ernst-Moritz-Arndt Universität Greifswald: Greifswald, Mecklenburg-Vorpommern, DE

2002-06 to 2004-11 | Dr. rer. nat (Pharmacy)
Education
Source: Self-asserted source
Timo H. J. Niedermeyer

Prenz'l Apotheke: Berlin, Berlin, DE

2001-11 to 2002-05
Education
Source: Self-asserted source
Timo H. J. Niedermeyer

Cardiff University: Cardiff, Cardiff, GB

2001-05 to 2001-11 (Pharmacy)
Education
Source: Self-asserted source
Timo H. J. Niedermeyer

Works (47)

Bulbillosins A - E, azaphilones from Tengochaeta bulbillosa sp. nov. (Chaetomiaceae), a root endophyte of the Chinese medicinal plant Aster tataricus

IMA Fungus
2025-02-17 | Journal article
DOI: 10.3897/imafungus.16.141036
Contributors: Diana Astrid Barrera-Adame; Yasmina Marin-Felix; Ana Kristin Wegener; Michael Lalk; Marc Stadler; Timo H. J. Niedermeyer
Source: check_circle
Crossref

Derivatization of Microcystins Can Increase Target Inhibition while Reducing Cellular Uptake

Journal of Natural Products
2025-01-24 | Journal article
DOI: 10.1021/acs.jnatprod.4c00688
Contributors: Laura L. Sallandt; Clemens A. Wolf; Sabine Schuster; Heike Enke; Dan Enke; Gerhard Wolber; Timo H. J. Niedermeyer
Source: check_circle
Crossref

UV–vis absorbance spectra, molar extinction coefficients and circular dichroism spectra for the two cyanobacterial metabolites anabaenopeptin A and anabaenopeptin B

Data in Brief
2024-12 | Journal article
DOI: 10.1016/j.dib.2024.110914
Contributors: Till Steiner; Franziska Schanbacher; Wolfram Lorenzen; Heike Enke; Elisabeth M.-L. Janssen; Timo H.J. Niedermeyer; Karl Gademann
Source: check_circle
Crossref

Mass Spectrometry Imaging of Coniine and Other Hemlock Alkaloids after On-Tissue Derivatization Reveals Distinct Alkaloid Distributions in the Plant

Journal of Natural Products
2024-10-25 | Journal article
DOI: 10.1021/acs.jnatprod.4c00445
Contributors: Diana A. Barrera-Adame; Sabine Schuster; Timo H. J. Niedermeyer
Source: check_circle
Crossref

More than just an eagle killer: The freshwater cyanobacterium <i>Aetokthonos hydrillicola</i> produces highly toxic dolastatin derivatives.

Proceedings of the National Academy of Sciences of the United States of America
2023-09 | Journal article
DOI: 10.1073/pnas.2219230120
PMID: 37751550
Contributors: Schwark M; Martínez Yerena JA; Röhrborn K; Hrouzek P; Divoká P; Štenclová L; Delawská K; Enke H; Vorreiter C; Wiley F et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Occurrence of aetokthonotoxin producer in natural samples - A PCR protocol for easy detection.

Harmful algae
2023-03 | Journal article
DOI: 10.1016/j.hal.2023.102425
PMID: 37220978
Contributors: Štenclová L; Wilde SB; Schwark M; Cullen JL; McWhorter SA; Niedermeyer THJ; Henderson WM; Mareš J
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Development of an agar-plug cultivation system for bioactivity assays of actinomycete strain collections

PLOS ONE
2021-11-05 | Journal article
DOI: 10.1371/journal.pone.0258934
Contributors: Nico Ortlieb; Marcos Pileggi; Elke Klenk; Andreas Kulik; Timo Horst Johannes Niedermeyer
Source: check_circle
Crossref

Codiaeum variegatum (L.) Rumph. ex A. Juss. (Euphorbiaceae): An overview of its botanical diversity, traditional uses, phytochemistry, pharmacological effects and perspectives towards developing its plant-based products

Journal of Ethnopharmacology
2021-09 | Journal article
DOI: 10.1016/j.jep.2021.114244
Contributors: Emmanuel Mfotie Njoya; Paul Moundipa Fewou; Timo H.J. Niedermeyer
Source: check_circle
Crossref

Bioreporters for direct mode of action-informed screening of antibiotic producer strains

Cell Chemical Biology
2021-08 | Journal article
DOI: 10.1016/j.chembiol.2021.02.022
Contributors: Katharina W. Wex; Julian S. Saur; Franziska Handel; Nico Ortlieb; Vladislav Mokeev; Andreas Kulik; Timo H.J. Niedermeyer; Yvonne Mast; Stephanie Grond; Anne Berscheid et al.
Source: check_circle
Crossref

Total Synthesis of Aetokthonotoxin, the Cyanobacterial Neurotoxin Causing Vacuolar Myelinopathy

Chemistry – A European Journal
2021-08-19 | Journal article
DOI: 10.1002/chem.202101848
Contributors: Manuel G. Ricardo; Markus Schwark; Dayma Llanes; Timo H. J. Niedermeyer; Bernhard Westermann
Source: check_circle
Crossref

Total Synthesis of Aetokthonotoxin, the Cyanobacterial Neurotoxin Causing Vacuolar Myelinopathy

Chemistry – A European Journal
2021-07-30 | Journal article
DOI: 10.1002/chem.202102615
Contributors: Manuel G. Ricardo; Markus Schwark; Dayma Llanes; Timo H. J. Niedermeyer; Bernhard Westermann
Source: check_circle
Crossref

Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy.

Science (New York, N.Y.)
2021-03 | Journal article
DOI: 10.1126/science.aax9050
PMID: 33766860
PMC: PMC8318203
Contributors: Breinlinger S; Phillips TJ; Haram BN; Mareš J; Martínez Yerena JA; Hrouzek P; Sobotka R; Henderson WM; Schmieder P; Williams SM et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Discovery of Thanafactin A, a Linear, Proline-Containing Octalipopeptide from Pseudomonas sp. SH-C52, Motivated by Genome Mining

Journal of Natural Products
2021-01-22 | Journal article
DOI: 10.1021/acs.jnatprod.0c01174
Contributors: Norbert Kirchner; Carolina Cano-Prieto; Anna-Christina Schulz-Fincke; Michael Gütschow; Nico Ortlieb; Julia Moschny; Timo H. J. Niedermeyer; Jeannie Horak; Michael Lämmerhofer; Menno van der Voort et al.
Source: check_circle
Crossref

Ambigols from the Cyanobacterium Fischerella ambigua Increase Prodigiosin Production in Serratia spp

ACS Chemical Biology
2020-11-20 | Journal article
DOI: 10.1021/acschembio.0c00554
Contributors: Tomasz Chilczuk; Rita Monson; Peter Schmieder; Vesselin Christov; Heike Enke; George Salmond; Timo Horst Johannes Niedermeyer
Source: check_circle
Crossref

Halogenation‐Guided Chemical Screening Provides Insight into Tjipanazole Biosynthesis by the Cyanobacterium Fischerella ambigua

ChemBioChem
2020-08-03 | Journal article
DOI: 10.1002/cbic.202000025
Contributors: Tomasz Chilczuk; Till F. Schäberle; Sahel Vahdati; Ute Mettal; Mustafa El Omari; Heike Enke; Michael Wiese; Gabriele M. König; Timo H. J. Niedermeyer
Source: check_circle
Crossref

Precursor-Directed Biosynthesis and Fluorescence Labeling of Clickable Microcystins

Journal of Natural Products
2020-06-26 | Journal article
DOI: 10.1021/acs.jnatprod.0c00251
Contributors: Julia Moschny; Wolfram Lorenzen; Alexandra Hilfer; Robert Eckenstaler; Stefan Jahns; Heike Enke; Dan Enke; Philipp Schneider; Ralf A. Benndorf; Timo H. J. Niedermeyer
Source: check_circle
Crossref

Nostotrebin 6 Related Cyclopentenediones and δ-Lactones with Broad Activity Spectrum Isolated from the Cultivation Medium of the Cyanobacterium Nostoc sp. CBT1153

Journal of Natural Products
2020-02-28 | Journal article
DOI: 10.1021/acs.jnatprod.9b00885
Contributors: Ronja Kossack; Steffen Breinlinger; Trang Nguyen; Julia Moschny; Jan Straetener; Anne Berscheid; Heike Brötz-Oesterhelt; Heike Enke; Tanja Schirmeister; Timo H. J. Niedermeyer
Source: check_circle
Crossref

Hapalindoles from the Cyanobacterium Hapalosiphon sp. Inhibit T Cell Proliferation.

Planta medica
2019-11 | Journal article
DOI: 10.1055/a-1045-5178
PMID: 31777053
Contributors: Chilczuk T; Steinborn C; Breinlinger S; Zimmermann-Klemd AM; Huber R; Enke H; Enke D; Niedermeyer THJ; Gründemann C
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Draft Genome Sequence of the Novonestmycin-Producing Strain Streptomyces sp. Z26, Isolated from Potato Rhizosphere in Morocco

Microbiology Resource Announcements
2019-01-03 | Journal article
DOI: 10.1128/MRA.01514-18
Contributors: Anina Buchmann; Carolina Cano-Prieto; Ahmed Nafis; Mustapha Barakate; Mohamed Baz; Lahcen Hassani; Nico Ortlieb; Timo H. J. Niedermeyer; Harald Gross; Catherine Putonti
Source: check_circle
Crossref

Xanthocidin Derivatives from the Endophytic Streptomyces sp. AcE210 Provide Insight into Xanthocidin Biosynthesis

ChemBioChem
2018-12-04 | Journal article
DOI: 10.1002/cbic.201800467
Contributors: Nico Ortlieb; Karin Bretzel; Andreas Kulik; Julian Haas; Steffen Lüdeke; Nadine Keilhofer; Silvia Diane Schrey; Harald Gross; Timo Horst Johannes Niedermeyer
Source: check_circle
Crossref

Draft Genome Sequence of the Xanthocidin-Producing Strain Streptomyces sp. AcE210, Isolated from a Root Nodule of Alnus glutinosa (L.)

Microbiology Resource Announcements
2018-10-11 | Journal article
DOI: 10.1128/MRA.01190-18
Contributors: Nico Ortlieb; Nadine Keilhofer; Silvia D. Schrey; Harald Gross; Timo H. J. Niedermeyer; Irene L. G. Newton
Source: check_circle
Crossref

Identification of a novel aminopolycarboxylic acid siderophore gene cluster encoding the biosynthesis of ethylenediaminesuccinic acid hydroxyarginine (EDHA).

Metallomics : integrated biometal science
2018-05 | Journal article
DOI: 10.1039/c8mt00009c
PMID: 29667664
Contributors: Spohn M; Edenhart S; Alanjary M; Ziemert N; Wibberg D; Kalinowski J; Niedermeyer THJ; Stegmann E; Wohlleben W
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Effects of extracts and compounds from Tricholoma populinum Lange on degranulation and IL-2/IL-8 secretion of immune cells.

Zeitschrift fur Naturforschung. C, Journal of biosciences
2017-07 | Journal article
DOI: 10.1515/znc-2016-0247
PMID: 28315853
Contributors: Merdivan S; Jenett-Siems K; Siems K; Niedermeyer THJ; Schultze N; Steinborn C; Gründemann C; Lindequist U
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).

Scientific reports
2016-09 | Journal article
DOI: 10.1038/srep32958
PMID: 27604544
PMC: PMC5015106
Contributors: Schreuder H; Liesum A; Lönze P; Stump H; Hoffmann H; Schiell M; Kurz M; Toti L; Bauer A; Kallus C et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Annotating and Interpreting Linear and Cyclic Peptide Tandem Mass Spectra.

Methods in molecular biology (Clifton, N.J.)
2016-01 | Journal article
DOI: 10.1007/978-1-4939-3375-4_13
PMID: 26831710
Contributors: Niedermeyer TH
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2.

Marine drugs
2016-01 | Journal article
DOI: 10.3390/md14010021
PMID: 26805858
PMC: PMC4728517
Contributors: Preisitsch M; Heiden SE; Beerbaum M; Niedermeyer TH; Schneefeld M; Herrmann J; Kumpfmüller J; Thürmer A; Neidhardt I; Wiesner C et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.

Journal of natural products
2015-12 | Journal article
DOI: 10.1021/acs.jnatprod.5b00768
PMID: 26684177
Contributors: Preisitsch M; Niedermeyer TH; Heiden SE; Neidhardt I; Kumpfmüller J; Wurster M; Harmrolfs K; Wiesner C; Enke H; Müller R et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Anti-infective Natural Products from Cyanobacteria.

2015-10 | Journal article
DOI: 10.1055/s-0035-1546055
PMID: 26085049
Contributors: Niedermeyer TH
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tu 365.

2015-10 | Journal article
PMID: 26433383
Contributors: Iftime D; Kulik A; Härtner T; Rohrer S; Niedermeyer TH; Stegmann E; Weber T; Wohlleben W
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2.

2015-09 | Journal article
DOI: 10.1038/ja.2015.79
PMID: 26412301
Contributors: Preisitsch M; Harmrolfs K; Pham HT; Heiden SE; Füssel A; Wiesner C; Pretsch A; Swiatecka-Hagenbruch M; Niedermeyer TH; Müller R et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2.

2015-03 | Journal article
DOI: 10.1038/ja.2014.118
PMID: 25182484
Contributors: Preisitsch M; Harmrolfs K; Pham HT; Heiden SE; Füssel A; Wiesner C; Pretsch A; Swiatecka-Hagenbruch M; Niedermeyer TH; Müller R et al.
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Engineering cyanobacteria for industrial products

2014 | Other
DOI:

10.1002/9781118402238.ch19

ISBN:

9781118402238
Source: Self-asserted source
Timo H. J. Niedermeyer via Crossref Metadata Search

Isolation of Microcystins from the Cyanobacterium Planktothrix rubescens Strain No80

2014 | Journal article
DOI:

10.1007/s13659-013-0001-3

Part of ISSN:

2192-2195
Source: Self-asserted source
Timo H. J. Niedermeyer via Crossref Metadata Search

Selectivity and Potency of Microcystin Congeners against OATP1B1 and OATP1B3 Expressing Cancer Cells.

2014 | Journal article
DOI:

10.1371/journal.pone.0091476

PMID:

24614281

PMC:

PMC3948918
Contributors: Niedermeyer TH; Daily A; Swiatecka-Hagenbruch M; Moscow JA
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

2013 | Journal article
DOI:

10.1007/s13659-013-0036-5

Part of ISSN:

2192-2209
Source: Self-asserted source
Timo H. J. Niedermeyer via Crossref Metadata Search

Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi.

2013-08 | Journal article
PMC: PMC4131579
Contributors: Niedermeyer THJ; Jira T; Lalk M; Lindequist U
Source: Self-asserted source
Timo H. J. Niedermeyer via Europe PubMed Central

10 Natural product drug discovery from microalgae

Other
DOI:

10.1515/9783110298321.169

ISBN:

9783110298321
Source: Self-asserted source
Timo H. J. Niedermeyer via Crossref Metadata Search

Antiviral Terpenoid Constituents ofGanodermapfeifferi

Journal article
DOI:

10.1021/np0501886
Source: Self-asserted source
Timo H. J. Niedermeyer

Inhibition of Human 5-Lipoxygenase and Anti-Neoplastic Effects by 2-Amino-1,4-Benzoquinones

Journal article
DOI:

10.2174/1573406410602060591
Source: Self-asserted source
Timo H. J. Niedermeyer

Laccase-induced cross-coupling of 4-aminobenzoic acid with para-dihydroxylated compounds 2,5-dihydroxy-N-(2-hydroxyethyl)-benzamide and 2,5-dihydroxybenzoic acid methyl ester

Journal article
DOI:

10.1016/j.molcatb.2005.06.001
Source: Self-asserted source
Timo H. J. Niedermeyer

mMass as a Software Tool for the Annotation of Cyclic Peptide Tandem Mass Spectra

Journal article
DOI:

10.1371/journal.pone.0044913
Source: Self-asserted source
Timo H. J. Niedermeyer

Novel Cephalosporins Synthesized by Amination of 2,5-Dihydroxybenzoic Acid Derivatives Using Fungal Laccases II

Journal article
DOI:

10.1248/cpb.55.412
Source: Self-asserted source
Timo H. J. Niedermeyer

Novel Penicillins Synthesized by Biotransformation Using Laccase from Trametes spec.

Journal article
DOI:

10.1248/cpb.54.632
Source: Self-asserted source
Timo H. J. Niedermeyer

Nuclear amination catalyzed by fungal laccases: Comparison of laccase catalyzed amination with known chemical routes to aminoquinones

Journal article
DOI:

10.1016/j.molcatb.2006.12.006
Source: Self-asserted source
Timo H. J. Niedermeyer

Nuclear Amination Catalyzed by Fungal Laccases: Reaction Products of p-Hydroquinones and Primary Aromatic Amines.

Journal article
DOI:

10.1002/chin.200532095
Source: Self-asserted source
Timo H. J. Niedermeyer

Nuclear Amination Catalyzed by Fungal Laccases:  Reaction Products ofp-Hydroquinones and Primary Aromatic Amines

Journal article
DOI:

10.1021/jo048454s
Source: Self-asserted source
Timo H. J. Niedermeyer

The Pharmacological Potential of Mushrooms

Journal article
DOI:

10.1093/ecam/neh107
Source: Self-asserted source
Timo H. J. Niedermeyer

Peer review (10 reviews for 3 publications/grants)

Review activity for ACS chemical biology. (3)
Review activity for Journal of natural products. (6)
Review activity for Journal of organic chemistry. (1)
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